TY  - JOUR
AU  - Cvetić-Antić, Tijana
AU  - Janosević, Dusica
AU  - Maksimović, Vuk
AU  - Zivić, Miroslav
AU  - Budimir, Snežana M
AU  - Glamočlija, Jasmina
AU  - Mitrović, Aleksandra Lj.
PY  - 2020
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1383
AB  - We present changes in Tacitus bellus antioxidative system that specifically correspond to subsequent phases of hemibiotroph Fusarium verticillioides infection revealed by histological analysis. T. bellus response to spore germination 6 h post inoculation (hpi), manifested as first oxidative burst, was characterized by transient decrease in malondialdehyde (MDA) content, transient increase in catalase (CAT), low level of superoxide dismutase (SOD) and peroxidase (POD) activity, as well as with transient decrease in total antioxidant capacity (TAC), total phenol content (TPC) and phenylalanine ammonium lyase activity (PAL), and no changes in polyphenol oxidase (PPO) activity, or phenolic profile. During the biotrophic phase of F. verticillioides infection, characterized by hyphae spread intercellularly in epidermal and mesophyll tissue, the host antioxidative system was suppressed. The transition to necrotrophic phase of F. verticillioides infection (inter- and intracellular colonization and sporulation), occurred 3-4 days post inoculation (dpi). During the necrotrophic phase, 5-7 dpi, slowed progression of colonization of T. bellus mesophyll cells occurred and it coincided with sharp increase in MDA content and CAT, SOD and POD activities, but the drop in TAC, TPC content, and PPO activity, as well as the production of phytotoxin fusaric acid. Presented results add to the knowledge of events and mechanisms related to the transition from biotrophy to necrotrophy in F. verticillioides.
PB  - Elsevier Gmbh, Munich
T2  - Journal of Plant Physiology
T1  - Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro
VL  - 244
DO  - 10.1016/j.jplph.2019.153086
ER  - 

@article{
author = "Cvetić-Antić, Tijana and Janosević, Dusica and Maksimović, Vuk and Zivić, Miroslav and Budimir, Snežana M and Glamočlija, Jasmina and Mitrović, Aleksandra Lj.",
year = "2020",
abstract = "We present changes in Tacitus bellus antioxidative system that specifically correspond to subsequent phases of hemibiotroph Fusarium verticillioides infection revealed by histological analysis. T. bellus response to spore germination 6 h post inoculation (hpi), manifested as first oxidative burst, was characterized by transient decrease in malondialdehyde (MDA) content, transient increase in catalase (CAT), low level of superoxide dismutase (SOD) and peroxidase (POD) activity, as well as with transient decrease in total antioxidant capacity (TAC), total phenol content (TPC) and phenylalanine ammonium lyase activity (PAL), and no changes in polyphenol oxidase (PPO) activity, or phenolic profile. During the biotrophic phase of F. verticillioides infection, characterized by hyphae spread intercellularly in epidermal and mesophyll tissue, the host antioxidative system was suppressed. The transition to necrotrophic phase of F. verticillioides infection (inter- and intracellular colonization and sporulation), occurred 3-4 days post inoculation (dpi). During the necrotrophic phase, 5-7 dpi, slowed progression of colonization of T. bellus mesophyll cells occurred and it coincided with sharp increase in MDA content and CAT, SOD and POD activities, but the drop in TAC, TPC content, and PPO activity, as well as the production of phytotoxin fusaric acid. Presented results add to the knowledge of events and mechanisms related to the transition from biotrophy to necrotrophy in F. verticillioides.",
publisher = "Elsevier Gmbh, Munich",
journal = "Journal of Plant Physiology",
title = "Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro",
volume = "244",
doi = "10.1016/j.jplph.2019.153086"
}

Cvetić-Antić, T., Janosević, D., Maksimović, V., Zivić, M., Budimir, S. M., Glamočlija, J.,& Mitrović, A. Lj.. (2020). Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro. in Journal of Plant Physiology
Elsevier Gmbh, Munich., 244.
https://doi.org/10.1016/j.jplph.2019.153086

Cvetić-Antić T, Janosević D, Maksimović V, Zivić M, Budimir SM, Glamočlija J, Mitrović AL. Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro. in Journal of Plant Physiology. 2020;244.
doi:10.1016/j.jplph.2019.153086 .

Cvetić-Antić, Tijana, Janosević, Dusica, Maksimović, Vuk, Zivić, Miroslav, Budimir, Snežana M, Glamočlija, Jasmina, Mitrović, Aleksandra Lj., "Biochemical and histological characterization of succulent plant Tacitus bellus response to Fusarium verticillioides infection in vitro" in Journal of Plant Physiology, 244 (2020),
https://doi.org/10.1016/j.jplph.2019.153086 . .

TY  - CONF
AU  - Zmejkoski, Danica Z.
AU  - Spasojević, Dragica
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Orlovska, Irina
AU  - Kozirovska, Natalia
AU  - Radotić, Ksenija
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2913
AB  - Biofilm-forming bacteria are recognized as a major impediment to wound healing. The aim of this study was to improve design of the formulations used for care of biofilm-infected wounds. Since lignins and lignin-derived compounds are known to have antibacterial properties especially efficient against biofilm-forming pathogens, the gel and membrane type of materials of enzymatically synthesized lignin model compound, dehydrogenative polymer of coniferyl alcohol (DHP) with alginate (Alg) and bacterial cellulose (BC) synthesized by culture Komagataeibacter intermedius IMBG180, were composed. The hydrogels were tested on Gram-negative P. aeruginosa (ATCC 27853) and S. typhimurium (ATCC 13311), Gram-positive bacteria L. monocytogenes (NCTC 7973) and S. aureus (ATCC 6538), as well as S. aureus #1*, S. aureus #2*, P. aeruginosa* and Serratia sp.* clinical human isolates obtained from patients’ wounds. DHP-Alg showed activity against all ofthe tested bacteria with minimal inhibitory concentrations (MICs) of 0.002–0.45 mg/mL and minimal bactericidal concentrations (MBCs) of 0.004–0.90 mg/mL. L. monocytogenes was the most susceptible. DHP-BC exhibited antibacterial activity on all tested bacteria, with exception of P. aeruginosa and S. aureus #1*. MICs and MBCs were in range of 0.22-0.42 mg/mL and 0.22-0.88 mg/mL, respectively. DHP-Alg gel and DHP-BC membranes, after initial release in the first hour of 34% and 19.26% of DHP, respectively, allowed the slow and continuous release of DHP in PBS solution. After 24 hours the amount of released antimicrobial substance from DHP-Alg and DHP-BC were 42.13% and 46.2%, respectively. Based on all obtained results, both hydrogels have the potential to be used in medical treatments as antibacterial agents.
PB  - Национална и универзитетска библиотека „Св. Климент Охридски“, Скопје
C3  - 25th Congress of SCTM
T1  - Antimicrobial composite polymers as potential agents in chronic wound healing
SP  - 223
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2913
ER  - 

@conference{
author = "Zmejkoski, Danica Z. and Spasojević, Dragica and Soković, Marina and Glamočlija, Jasmina and Orlovska, Irina and Kozirovska, Natalia and Radotić, Ksenija",
year = "2018",
abstract = "Biofilm-forming bacteria are recognized as a major impediment to wound healing. The aim of this study was to improve design of the formulations used for care of biofilm-infected wounds. Since lignins and lignin-derived compounds are known to have antibacterial properties especially efficient against biofilm-forming pathogens, the gel and membrane type of materials of enzymatically synthesized lignin model compound, dehydrogenative polymer of coniferyl alcohol (DHP) with alginate (Alg) and bacterial cellulose (BC) synthesized by culture Komagataeibacter intermedius IMBG180, were composed. The hydrogels were tested on Gram-negative P. aeruginosa (ATCC 27853) and S. typhimurium (ATCC 13311), Gram-positive bacteria L. monocytogenes (NCTC 7973) and S. aureus (ATCC 6538), as well as S. aureus #1*, S. aureus #2*, P. aeruginosa* and Serratia sp.* clinical human isolates obtained from patients’ wounds. DHP-Alg showed activity against all ofthe tested bacteria with minimal inhibitory concentrations (MICs) of 0.002–0.45 mg/mL and minimal bactericidal concentrations (MBCs) of 0.004–0.90 mg/mL. L. monocytogenes was the most susceptible. DHP-BC exhibited antibacterial activity on all tested bacteria, with exception of P. aeruginosa and S. aureus #1*. MICs and MBCs were in range of 0.22-0.42 mg/mL and 0.22-0.88 mg/mL, respectively. DHP-Alg gel and DHP-BC membranes, after initial release in the first hour of 34% and 19.26% of DHP, respectively, allowed the slow and continuous release of DHP in PBS solution. After 24 hours the amount of released antimicrobial substance from DHP-Alg and DHP-BC were 42.13% and 46.2%, respectively. Based on all obtained results, both hydrogels have the potential to be used in medical treatments as antibacterial agents.",
publisher = "Национална и универзитетска библиотека „Св. Климент Охридски“, Скопје",
journal = "25th Congress of SCTM",
title = "Antimicrobial composite polymers as potential agents in chronic wound healing",
pages = "223",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2913"
}

Zmejkoski, D. Z., Spasojević, D., Soković, M., Glamočlija, J., Orlovska, I., Kozirovska, N.,& Radotić, K.. (2018). Antimicrobial composite polymers as potential agents in chronic wound healing. in 25th Congress of SCTM
Национална и универзитетска библиотека „Св. Климент Охридски“, Скопје., 223.
https://hdl.handle.net/21.15107/rcub_rimsi_2913

Zmejkoski DZ, Spasojević D, Soković M, Glamočlija J, Orlovska I, Kozirovska N, Radotić K. Antimicrobial composite polymers as potential agents in chronic wound healing. in 25th Congress of SCTM. 2018;:223.
https://hdl.handle.net/21.15107/rcub_rimsi_2913 .

Zmejkoski, Danica Z., Spasojević, Dragica, Soković, Marina, Glamočlija, Jasmina, Orlovska, Irina, Kozirovska, Natalia, Radotić, Ksenija, "Antimicrobial composite polymers as potential agents in chronic wound healing" in 25th Congress of SCTM (2018):223,
https://hdl.handle.net/21.15107/rcub_rimsi_2913 .

TY  - JOUR
AU  - Zmejkoski, Danica
AU  - Spasojević, Dragica
AU  - Orlovska, Irina
AU  - Kozyrovska, Natalia
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Dmitrović, Svetlana
AU  - Matović, Branko
AU  - Tasić, Nikola
AU  - Maksimović, Vuk
AU  - Sosnin, Mikhail
AU  - Radotić, Ksenija
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1157
AB  - Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.
PB  - Elsevier, Amsterdam
T2  - International Journal of Biological Macromolecules
T1  - Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing
EP  - 503
SP  - 494
VL  - 118
DO  - 10.1016/j.ijbiomac.2018.06.067
ER  - 

@article{
author = "Zmejkoski, Danica and Spasojević, Dragica and Orlovska, Irina and Kozyrovska, Natalia and Soković, Marina and Glamočlija, Jasmina and Dmitrović, Svetlana and Matović, Branko and Tasić, Nikola and Maksimović, Vuk and Sosnin, Mikhail and Radotić, Ksenija",
year = "2018",
abstract = "Lignins and lignin-derived compounds are known to have antibacterial properties. The wound healing agents in the form of dressings produce faster skin repair and decrease pain in patients. In order to create an efficient antimicrobial agent in the form of dressing in the treatment of chronic wounds, a composite hydrogel of bacterial cellulose (BC) and dehydrogenative polymer of coniferyl alcohol (DHP), BC-DHP, was designed. Novel composite showed inhibitory or bactericidal effects against selected pathogenic bacteria, including clinically isolated ones. The highest release rate of DHP was in the first hour, while after 24 h there was still slow release of small amounts of DHP from BC-DHP during 72 h monitoring. High-performance liquid chromatography coupled with mass-spectrometry showed that BC-DHP releases DHP oligomers, which are proposed to be antimicrobially active DHP fractions. Scanning electron microscopy and atomic force microscopy micrographs proved a dose-dependent interaction of DHP with BC, which resulted in a decrease of the pore number and size in the cellulose membrane. The Fourier-transform infrared absorption spectra of the BC-DHP showed that DHP was partly bound to the BC matrix. The swelling and crystallinity degree were dose-dependent. All obtained results confirmed BC-DHP composite as a promising hydrogel for wounds healing.",
publisher = "Elsevier, Amsterdam",
journal = "International Journal of Biological Macromolecules",
title = "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing",
pages = "503-494",
volume = "118",
doi = "10.1016/j.ijbiomac.2018.06.067"
}

Zmejkoski, D., Spasojević, D., Orlovska, I., Kozyrovska, N., Soković, M., Glamočlija, J., Dmitrović, S., Matović, B., Tasić, N., Maksimović, V., Sosnin, M.,& Radotić, K.. (2018). Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules
Elsevier, Amsterdam., 118, 494-503.
https://doi.org/10.1016/j.ijbiomac.2018.06.067

Zmejkoski D, Spasojević D, Orlovska I, Kozyrovska N, Soković M, Glamočlija J, Dmitrović S, Matović B, Tasić N, Maksimović V, Sosnin M, Radotić K. Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing. in International Journal of Biological Macromolecules. 2018;118:494-503.
doi:10.1016/j.ijbiomac.2018.06.067 .

Zmejkoski, Danica, Spasojević, Dragica, Orlovska, Irina, Kozyrovska, Natalia, Soković, Marina, Glamočlija, Jasmina, Dmitrović, Svetlana, Matović, Branko, Tasić, Nikola, Maksimović, Vuk, Sosnin, Mikhail, Radotić, Ksenija, "Bacterial cellulose-lignin composite hydrogel as a promising agent in chronic wound healing" in International Journal of Biological Macromolecules, 118 (2018):494-503,
https://doi.org/10.1016/j.ijbiomac.2018.06.067 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Dimitrić-Marković, Jasmina
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
PY  - 2017
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1090
AB  - Anti-biofilm activity of three anthocyanidins (pelargonidin, cyanidin and delphinidin) was evaluated for the first time at in vitro conditions. All the compounds reduced the formation of Pseudomonas aeruginosa PAO1 biofilm at low sub-MIC (0.125 MIC) with delphinidin (c 56.25g/mL) being the most active (43%). In comparison, ampicillin (c 93.75g/mL) and streptomycin (c 21.25g/mL) (used as positive controls) were considerably less effective at the same sub-MIC (8 and 12%, respectively). Furthermore, at 0.5 MIC (c 225g/mL) this anthocyanidin molecule partly reduced the bacterial protrusions. However, no any of the aforementioned compounds inhibited the production of pyocyanin by the bacterial strain P. aeruginosa PAO1. Taken all together, the delphinidin scaffold could be taken into consideration for the design of the novel and more effective anti-biofilm agents inspired by the anthocyanidins.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1
EP  - 1180
IS  - 10
SP  - 1177
VL  - 31
DO  - 10.1080/14786419.2016.1222386
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Dimitrić-Marković, Jasmina and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina",
year = "2017",
abstract = "Anti-biofilm activity of three anthocyanidins (pelargonidin, cyanidin and delphinidin) was evaluated for the first time at in vitro conditions. All the compounds reduced the formation of Pseudomonas aeruginosa PAO1 biofilm at low sub-MIC (0.125 MIC) with delphinidin (c 56.25g/mL) being the most active (43%). In comparison, ampicillin (c 93.75g/mL) and streptomycin (c 21.25g/mL) (used as positive controls) were considerably less effective at the same sub-MIC (8 and 12%, respectively). Furthermore, at 0.5 MIC (c 225g/mL) this anthocyanidin molecule partly reduced the bacterial protrusions. However, no any of the aforementioned compounds inhibited the production of pyocyanin by the bacterial strain P. aeruginosa PAO1. Taken all together, the delphinidin scaffold could be taken into consideration for the design of the novel and more effective anti-biofilm agents inspired by the anthocyanidins.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1",
pages = "1180-1177",
number = "10",
volume = "31",
doi = "10.1080/14786419.2016.1222386"
}

Pejin, B., Ciric, A., Dimitrić-Marković, J., Glamočlija, J., Nikolic, M.,& Soković, M.. (2017). An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 31(10), 1177-1180.
https://doi.org/10.1080/14786419.2016.1222386

Pejin B, Ciric A, Dimitrić-Marković J, Glamočlija J, Nikolic M, Soković M. An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1. in Natural Product Research. 2017;31(10):1177-1180.
doi:10.1080/14786419.2016.1222386 .

Pejin, Boris, Ciric, Ana, Dimitrić-Marković, Jasmina, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1" in Natural Product Research, 31, no. 10 (2017):1177-1180,
https://doi.org/10.1080/14786419.2016.1222386 . .

TY  - JOUR
AU  - Spasojević, Dragica
AU  - Zmejkoski, Danica
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
AU  - Milošević, Verica Lj.
AU  - Jaric, Ivana
AU  - Stojanović, Marijana
AU  - Marinković, Emilija
AU  - Barisani-Asenbauer, Talin
AU  - Prodanović, Radivoje
AU  - Jovanović, Milos
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/983
AB  - Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP-Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments.
PB  - Elsevier, Amsterdam
T2  - International Journal of Antimicrobial Agents
T1  - Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment
EP  - 735
IS  - 6
SP  - 732
VL  - 48
DO  - 10.1016/j.ijantimicag.2016.08.014
ER  - 

@article{
author = "Spasojević, Dragica and Zmejkoski, Danica and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina and Milošević, Verica Lj. and Jaric, Ivana and Stojanović, Marijana and Marinković, Emilija and Barisani-Asenbauer, Talin and Prodanović, Radivoje and Jovanović, Milos and Radotić, Ksenija",
year = "2016",
abstract = "Nowadays bacterial resistance to known antibiotics is a serious health problem. In order to achieve more efficient treatment, lately there is an effort to find new substances, such as certain biomaterials, that are non-toxic to humans with antibiotic potential. Lignins and lignin-derived compounds have been proposed to be good candidates for use in medicine and health maintenance. In this study, the antibacterial activity of the lignin model polymer dehydrogenate polymer (DHP) in alginate hydrogel (Alg) was studied. The obtained results show that DHP-Alg has strong antimicrobial activity against several bacterial strains and biofilms and does not have a toxic effect on human epithelial cells. These results strongly suggest its application as a wound healing agent or as an adjunct substance for wound treatments.",
publisher = "Elsevier, Amsterdam",
journal = "International Journal of Antimicrobial Agents",
title = "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment",
pages = "735-732",
number = "6",
volume = "48",
doi = "10.1016/j.ijantimicag.2016.08.014"
}

Spasojević, D., Zmejkoski, D., Glamočlija, J., Nikolic, M., Soković, M., Milošević, V. Lj., Jaric, I., Stojanović, M., Marinković, E., Barisani-Asenbauer, T., Prodanović, R., Jovanović, M.,& Radotić, K.. (2016). Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents
Elsevier, Amsterdam., 48(6), 732-735.
https://doi.org/10.1016/j.ijantimicag.2016.08.014

Spasojević D, Zmejkoski D, Glamočlija J, Nikolic M, Soković M, Milošević VL, Jaric I, Stojanović M, Marinković E, Barisani-Asenbauer T, Prodanović R, Jovanović M, Radotić K. Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment. in International Journal of Antimicrobial Agents. 2016;48(6):732-735.
doi:10.1016/j.ijantimicag.2016.08.014 .

Spasojević, Dragica, Zmejkoski, Danica, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, Milošević, Verica Lj., Jaric, Ivana, Stojanović, Marijana, Marinković, Emilija, Barisani-Asenbauer, Talin, Prodanović, Radivoje, Jovanović, Milos, Radotić, Ksenija, "Lignin model compound in alginate hydrogel: a strong antimicrobial agent with high potential in wound treatment" in International Journal of Antimicrobial Agents, 48, no. 6 (2016):732-735,
https://doi.org/10.1016/j.ijantimicag.2016.08.014 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Horvatović, Mladen
AU  - Jurca, Tamara
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/955
AB  - The antimicrobial activity of five crude extracts of the freshwater bryozoan Pectinatella magnifica (Leidy, 1851) was evaluated in vitro for the first time. P. magnifica acetone extract exhibited the highest antibacterial activity (minimum inhibitory concentrations (MIC) 0.004-0.350mg/mL and MBC 0.007-0.500mg/mL), while its methanol extract showed the most promising antifungal activity (MIC 0.03-0.12mg/mL and MFC 0.06-0.25mg/mL). Furthermore, at a concentration of 0.25 MIC, the methanol extract reduced biofilm formation of the bacterial strain Pseudomonas aeruginosa PAO1 in a considerable extent (59.14%). FTIR spectra of the most active extracts indicate the presence of carbonyl compounds, long-chain alcohols and/or sterols. According to the experimental data obtained, P. magnifica methanol extract may be considered as a good resource of novel natural products with potent antibiofilm activity against the bacterium well known for its resistance. [GRAPHCIS].
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica
EP  - 1843
IS  - 16
SP  - 1839
VL  - 30
DO  - 10.1080/14786419.2015.1068773
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Horvatović, Mladen and Jurca, Tamara and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina",
year = "2016",
abstract = "The antimicrobial activity of five crude extracts of the freshwater bryozoan Pectinatella magnifica (Leidy, 1851) was evaluated in vitro for the first time. P. magnifica acetone extract exhibited the highest antibacterial activity (minimum inhibitory concentrations (MIC) 0.004-0.350mg/mL and MBC 0.007-0.500mg/mL), while its methanol extract showed the most promising antifungal activity (MIC 0.03-0.12mg/mL and MFC 0.06-0.25mg/mL). Furthermore, at a concentration of 0.25 MIC, the methanol extract reduced biofilm formation of the bacterial strain Pseudomonas aeruginosa PAO1 in a considerable extent (59.14%). FTIR spectra of the most active extracts indicate the presence of carbonyl compounds, long-chain alcohols and/or sterols. According to the experimental data obtained, P. magnifica methanol extract may be considered as a good resource of novel natural products with potent antibiofilm activity against the bacterium well known for its resistance. [GRAPHCIS].",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica",
pages = "1843-1839",
number = "16",
volume = "30",
doi = "10.1080/14786419.2015.1068773"
}

Pejin, B., Ciric, A., Horvatović, M., Jurca, T., Glamočlija, J., Nikolic, M.,& Soković, M.. (2016). An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 30(16), 1839-1843.
https://doi.org/10.1080/14786419.2015.1068773

Pejin B, Ciric A, Horvatović M, Jurca T, Glamočlija J, Nikolic M, Soković M. An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica. in Natural Product Research. 2016;30(16):1839-1843.
doi:10.1080/14786419.2015.1068773 .

Pejin, Boris, Ciric, Ana, Horvatović, Mladen, Jurca, Tamara, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica" in Natural Product Research, 30, no. 16 (2016):1839-1843,
https://doi.org/10.1080/14786419.2015.1068773 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Karaman, Ivo
AU  - Horvatović, Mladen
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/954
AB  - The antibiofilm and possible antiquorum sensing effects against the strain Pseudomonas aeruginosa PAO1 of five crude extracts of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) were evaluated in vitro for the first time. H. punctata ethyl acetate extract (HpEtAc) exhibited the highest antibiofilm activity reducing the biofilm formation of P. aeruginosa PAO1 in the range of 80.63-88.13%. While all tested extracts reduced the twitching motility of the aforementioned bacterial strain, HpEtAc showed to be the most effective. Finally, at a concentration of 0.5 MIC, the same extract mostly inhibited the production of pyocyanin by P. aeruginosa PAO1 (71.53%). In comparison both with the positive controls used (streptomycin and ampicillin, 67.13 and 69.77%, respectively), HpEtAc was found to inhibit pyocyanin in a higher extent. An extensive chemical characterisation of this particular extract may result in isolation and identification of novel lead compounds targeting P. aeruginosa, an opportunistic human pathogen. [GRAPHCIS].
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1
EP  - 1850
IS  - 16
SP  - 1847
VL  - 30
DO  - 10.1080/14786419.2015.1072714
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Karaman, Ivo and Horvatović, Mladen and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina",
year = "2016",
abstract = "The antibiofilm and possible antiquorum sensing effects against the strain Pseudomonas aeruginosa PAO1 of five crude extracts of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) were evaluated in vitro for the first time. H. punctata ethyl acetate extract (HpEtAc) exhibited the highest antibiofilm activity reducing the biofilm formation of P. aeruginosa PAO1 in the range of 80.63-88.13%. While all tested extracts reduced the twitching motility of the aforementioned bacterial strain, HpEtAc showed to be the most effective. Finally, at a concentration of 0.5 MIC, the same extract mostly inhibited the production of pyocyanin by P. aeruginosa PAO1 (71.53%). In comparison both with the positive controls used (streptomycin and ampicillin, 67.13 and 69.77%, respectively), HpEtAc was found to inhibit pyocyanin in a higher extent. An extensive chemical characterisation of this particular extract may result in isolation and identification of novel lead compounds targeting P. aeruginosa, an opportunistic human pathogen. [GRAPHCIS].",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1",
pages = "1850-1847",
number = "16",
volume = "30",
doi = "10.1080/14786419.2015.1072714"
}

Pejin, B., Ciric, A., Karaman, I., Horvatović, M., Glamočlija, J., Nikolic, M.,& Soković, M.. (2016). In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 30(16), 1847-1850.
https://doi.org/10.1080/14786419.2015.1072714

Pejin B, Ciric A, Karaman I, Horvatović M, Glamočlija J, Nikolic M, Soković M. In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1. in Natural Product Research. 2016;30(16):1847-1850.
doi:10.1080/14786419.2015.1072714 .

Pejin, Boris, Ciric, Ana, Karaman, Ivo, Horvatović, Mladen, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1" in Natural Product Research, 30, no. 16 (2016):1847-1850,
https://doi.org/10.1080/14786419.2015.1072714 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Dimitrić-Marković, Jasmina
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Stanimirović, Bojana
AU  - Soković, Marina
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/852
AB  - This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Biotechnology
T1  - Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro
EP  - 737
IS  - 8
SP  - 733
VL  - 16
DO  - 10.2174/1389201016666150505121951
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Dimitrić-Marković, Jasmina and Glamočlija, Jasmina and Nikolic, Milos and Stanimirović, Bojana and Soković, Marina",
year = "2015",
abstract = "This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Biotechnology",
title = "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro",
pages = "737-733",
number = "8",
volume = "16",
doi = "10.2174/1389201016666150505121951"
}

Pejin, B., Ciric, A., Dimitrić-Marković, J., Glamočlija, J., Nikolic, M., Stanimirović, B.,& Soković, M.. (2015). Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology
Bentham Science Publ Ltd, Sharjah., 16(8), 733-737.
https://doi.org/10.2174/1389201016666150505121951

Pejin B, Ciric A, Dimitrić-Marković J, Glamočlija J, Nikolic M, Stanimirović B, Soković M. Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology. 2015;16(8):733-737.
doi:10.2174/1389201016666150505121951 .

Pejin, Boris, Ciric, Ana, Dimitrić-Marković, Jasmina, Glamočlija, Jasmina, Nikolic, Milos, Stanimirović, Bojana, Soković, Marina, "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro" in Current Pharmaceutical Biotechnology, 16, no. 8 (2015):733-737,
https://doi.org/10.2174/1389201016666150505121951 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/832
AB  - Anti-quorum sensing activity of the diterpene phytol was evaluated in vitro for the first time. This compound (at three sub-MIC concentrations - 0.5, 0.25 and 0.125 MIC, respectively) reduced the formation of Pseudomonas aeruginosa PAO1 biofilm in the range of 74.00-84.33% exhibiting higher activity than the both positive controls used, streptomycin and ampicillin. Phytol (0.5 MIC) also effectively reduced P. aeruginosa twitching and flagella motility. Indeed, the bacteria treated were incapable of producing a twitching zone and had almost round, smooth and regular colony edges. Finally, the tested compound (0.5 MIC) exhibited good P. aeruginosa pyocyanin inhibitory activity (51.94%) practically to the same extent as streptomycin (52.09%). According to the experimental data obtained, this phytol property may inspire design of medical foods targeting P. aeruginosa quorum sensing activity.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - In vitro anti-quorum sensing activity of phytol
EP  - 377
IS  - 4
SP  - 374
VL  - 29
DO  - 10.1080/14786419.2014.945088
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina",
year = "2015",
abstract = "Anti-quorum sensing activity of the diterpene phytol was evaluated in vitro for the first time. This compound (at three sub-MIC concentrations - 0.5, 0.25 and 0.125 MIC, respectively) reduced the formation of Pseudomonas aeruginosa PAO1 biofilm in the range of 74.00-84.33% exhibiting higher activity than the both positive controls used, streptomycin and ampicillin. Phytol (0.5 MIC) also effectively reduced P. aeruginosa twitching and flagella motility. Indeed, the bacteria treated were incapable of producing a twitching zone and had almost round, smooth and regular colony edges. Finally, the tested compound (0.5 MIC) exhibited good P. aeruginosa pyocyanin inhibitory activity (51.94%) practically to the same extent as streptomycin (52.09%). According to the experimental data obtained, this phytol property may inspire design of medical foods targeting P. aeruginosa quorum sensing activity.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "In vitro anti-quorum sensing activity of phytol",
pages = "377-374",
number = "4",
volume = "29",
doi = "10.1080/14786419.2014.945088"
}

Pejin, B., Ciric, A., Glamočlija, J., Nikolic, M.,& Soković, M.. (2015). In vitro anti-quorum sensing activity of phytol. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 29(4), 374-377.
https://doi.org/10.1080/14786419.2014.945088

Pejin B, Ciric A, Glamočlija J, Nikolic M, Soković M. In vitro anti-quorum sensing activity of phytol. in Natural Product Research. 2015;29(4):374-377.
doi:10.1080/14786419.2014.945088 .

Pejin, Boris, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "In vitro anti-quorum sensing activity of phytol" in Natural Product Research, 29, no. 4 (2015):374-377,
https://doi.org/10.1080/14786419.2014.945088 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ciric, Ana D
AU  - Nikolic, Milos MN
AU  - Radotić, Ksenija
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/759
AB  - The antiradical activity of phytol was evaluated by electron paramagnetic resonance towards hydroxyl radical (root OH), superoxide anion radical (), methoxy radical (root CH2OH), carbon-dioxide anion radical (), as well as towards nitric-oxide radical (root NO) and 2,2-diphenyl-1-picrylhydrazyl (root DPPH) radical. It reduced the production of all tested radicals showing more promising activity against , root CH2OH and root DPPH radicals (56%, 50% and 48%, respectively) in comparison with root NO, and root OH radicals (38%, 23% and 15%, respectively). The antimicrobial activity of phytol was evaluated by the microdilution method against eight bacterial and eight fungal strains. To varying degrees, it was proven to be active against all tested bacteria and fungi (MIC 0.003-0.038mg/mL and MBC 0.013-0.052mg/mL, MIC 0.008-0.016mg/mL and MFC 0.090-0.520mg/mL, respectively). According to the obtained results, medical foods containing phytol may support development of new therapies for heart disease.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Further in vitro evaluation of antiradical and antimicrobial activities of phytol
EP  - 376
IS  - 6
SP  - 372
VL  - 28
DO  - 10.1080/14786419.2013.869692
ER  - 

@article{
author = "Pejin, Boris and Savić, Aleksandar G and Soković, Marina and Glamočlija, Jasmina and Ciric, Ana D and Nikolic, Milos MN and Radotić, Ksenija and Mojović, Miloš",
year = "2014",
abstract = "The antiradical activity of phytol was evaluated by electron paramagnetic resonance towards hydroxyl radical (root OH), superoxide anion radical (), methoxy radical (root CH2OH), carbon-dioxide anion radical (), as well as towards nitric-oxide radical (root NO) and 2,2-diphenyl-1-picrylhydrazyl (root DPPH) radical. It reduced the production of all tested radicals showing more promising activity against , root CH2OH and root DPPH radicals (56%, 50% and 48%, respectively) in comparison with root NO, and root OH radicals (38%, 23% and 15%, respectively). The antimicrobial activity of phytol was evaluated by the microdilution method against eight bacterial and eight fungal strains. To varying degrees, it was proven to be active against all tested bacteria and fungi (MIC 0.003-0.038mg/mL and MBC 0.013-0.052mg/mL, MIC 0.008-0.016mg/mL and MFC 0.090-0.520mg/mL, respectively). According to the obtained results, medical foods containing phytol may support development of new therapies for heart disease.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Further in vitro evaluation of antiradical and antimicrobial activities of phytol",
pages = "376-372",
number = "6",
volume = "28",
doi = "10.1080/14786419.2013.869692"
}

Pejin, B., Savić, A. G., Soković, M., Glamočlija, J., Ciric, A. D., Nikolic, M. M., Radotić, K.,& Mojović, M.. (2014). Further in vitro evaluation of antiradical and antimicrobial activities of phytol. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(6), 372-376.
https://doi.org/10.1080/14786419.2013.869692

Pejin B, Savić AG, Soković M, Glamočlija J, Ciric AD, Nikolic MM, Radotić K, Mojović M. Further in vitro evaluation of antiradical and antimicrobial activities of phytol. in Natural Product Research. 2014;28(6):372-376.
doi:10.1080/14786419.2013.869692 .

Pejin, Boris, Savić, Aleksandar G, Soković, Marina, Glamočlija, Jasmina, Ciric, Ana D, Nikolic, Milos MN, Radotić, Ksenija, Mojović, Miloš, "Further in vitro evaluation of antiradical and antimicrobial activities of phytol" in Natural Product Research, 28, no. 6 (2014):372-376,
https://doi.org/10.1080/14786419.2013.869692 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Talevska, Aleksandra
AU  - Ciric, Ana
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Talevski, Trajce
AU  - Soković, Marina
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/806
AB  - The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching and flagella motility) of two crude extracts (methanol and acetone) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for the first time. Both extracts demonstrated P. aeruginosa pyocyanin inhibitory activity, reducing its production for 49.90% and 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% and 53.99%, respectively) than ampicillin (30.84%). Finally, O. rotunda extracts effectively reduced twitching and flagella motility of P. aeruginosa. Taken all together, these results suggest that endemic sponge species from the oldest lake in Europe may offer novel bioactive natural products with promising medicinal potential towards P. aeruginosa infections.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa
EP  - 2333
IS  - 24
SP  - 2330
VL  - 28
DO  - 10.1080/14786419.2014.934239
ER  - 

@article{
author = "Pejin, Boris and Talevska, Aleksandra and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and Talevski, Trajce and Soković, Marina",
year = "2014",
abstract = "The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching and flagella motility) of two crude extracts (methanol and acetone) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for the first time. Both extracts demonstrated P. aeruginosa pyocyanin inhibitory activity, reducing its production for 49.90% and 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% and 53.99%, respectively) than ampicillin (30.84%). Finally, O. rotunda extracts effectively reduced twitching and flagella motility of P. aeruginosa. Taken all together, these results suggest that endemic sponge species from the oldest lake in Europe may offer novel bioactive natural products with promising medicinal potential towards P. aeruginosa infections.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa",
pages = "2333-2330",
number = "24",
volume = "28",
doi = "10.1080/14786419.2014.934239"
}

Pejin, B., Talevska, A., Ciric, A., Glamočlija, J., Nikolic, M., Talevski, T.,& Soković, M.. (2014). Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(24), 2330-2333.
https://doi.org/10.1080/14786419.2014.934239

Pejin B, Talevska A, Ciric A, Glamočlija J, Nikolic M, Talevski T, Soković M. Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa. in Natural Product Research. 2014;28(24):2330-2333.
doi:10.1080/14786419.2014.934239 .

Pejin, Boris, Talevska, Aleksandra, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, Talevski, Trajce, Soković, Marina, "Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa" in Natural Product Research, 28, no. 24 (2014):2330-2333,
https://doi.org/10.1080/14786419.2014.934239 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Talevska, Aleksandra
AU  - Ciric, Ana
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Talevski, Trajce
AU  - Soković, Marina
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/784
AB  - The antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepwater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)
EP  - 1494
IS  - 18
SP  - 1489
VL  - 28
DO  - 10.1080/14786419.2014.911297
ER  - 

@article{
author = "Pejin, Boris and Talevska, Aleksandra and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and Talevski, Trajce and Soković, Marina",
year = "2014",
abstract = "The antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepwater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)",
pages = "1494-1489",
number = "18",
volume = "28",
doi = "10.1080/14786419.2014.911297"
}

Pejin, B., Talevska, A., Ciric, A., Glamočlija, J., Nikolic, M., Talevski, T.,& Soković, M.. (2014). In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937). in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(18), 1489-1494.
https://doi.org/10.1080/14786419.2014.911297

Pejin B, Talevska A, Ciric A, Glamočlija J, Nikolic M, Talevski T, Soković M. In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937). in Natural Product Research. 2014;28(18):1489-1494.
doi:10.1080/14786419.2014.911297 .

Pejin, Boris, Talevska, Aleksandra, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, Talevski, Trajce, Soković, Marina, "In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)" in Natural Product Research, 28, no. 18 (2014):1489-1494,
https://doi.org/10.1080/14786419.2014.911297 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Iodice, Carmine
AU  - Tommonaro, Giuseppina
AU  - Stanimirović, Bojana
AU  - Ciric, Ana
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - De Rosa, Salvatore
AU  - Soković, Marina
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/776
AB  - This work extends in vitro screening of antimicrobial activity of the sesquiterpene hydroquinone avarol, a main secondary metabolite of the Mediterranean sponge species Dysidea avara. The antimicrobial activity was in part evaluated by microdilution method against selected bacterial and fungal strains. Additionally, the screening included evaluation of anti-quorum sensing (anti-QS) effects. At a different extent avarol was proven to be active against all the microorganisms tested (MIC 0.002-0.008 mg/mL and MBC 0.004-0.016 mg/mL; MIC 0.004-0.015 mg/mL and MFC 0.008-0.030 mg/mL; respectively). This marine natural product also showed moderate anti-QS effects, reducing Pseudomonas aeruginosa PAO1 biofilm formation (75%), its twitching and protrusions motilities as well as pyocianin production (39%). According to the best of our knowledge, this is the first report both on avarol anti Gram-negative bacterial activity and anti-QS effects.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Biotechnology
T1  - Further in vitro Evaluation of Antimicrobial Activity of the Marine Sesquiterpene Hydroquinone Avarol
EP  - 588
IS  - 6
SP  - 583
VL  - 15
DO  - 10.2174/138920101506140910152253
ER  - 

@article{
author = "Pejin, Boris and Iodice, Carmine and Tommonaro, Giuseppina and Stanimirović, Bojana and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and De Rosa, Salvatore and Soković, Marina",
year = "2014",
abstract = "This work extends in vitro screening of antimicrobial activity of the sesquiterpene hydroquinone avarol, a main secondary metabolite of the Mediterranean sponge species Dysidea avara. The antimicrobial activity was in part evaluated by microdilution method against selected bacterial and fungal strains. Additionally, the screening included evaluation of anti-quorum sensing (anti-QS) effects. At a different extent avarol was proven to be active against all the microorganisms tested (MIC 0.002-0.008 mg/mL and MBC 0.004-0.016 mg/mL; MIC 0.004-0.015 mg/mL and MFC 0.008-0.030 mg/mL; respectively). This marine natural product also showed moderate anti-QS effects, reducing Pseudomonas aeruginosa PAO1 biofilm formation (75%), its twitching and protrusions motilities as well as pyocianin production (39%). According to the best of our knowledge, this is the first report both on avarol anti Gram-negative bacterial activity and anti-QS effects.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Biotechnology",
title = "Further in vitro Evaluation of Antimicrobial Activity of the Marine Sesquiterpene Hydroquinone Avarol",
pages = "588-583",
number = "6",
volume = "15",
doi = "10.2174/138920101506140910152253"
}

Pejin, B., Iodice, C., Tommonaro, G., Stanimirović, B., Ciric, A., Glamočlija, J., Nikolic, M., De Rosa, S.,& Soković, M.. (2014). Further in vitro Evaluation of Antimicrobial Activity of the Marine Sesquiterpene Hydroquinone Avarol. in Current Pharmaceutical Biotechnology
Bentham Science Publ Ltd, Sharjah., 15(6), 583-588.
https://doi.org/10.2174/138920101506140910152253

Pejin B, Iodice C, Tommonaro G, Stanimirović B, Ciric A, Glamočlija J, Nikolic M, De Rosa S, Soković M. Further in vitro Evaluation of Antimicrobial Activity of the Marine Sesquiterpene Hydroquinone Avarol. in Current Pharmaceutical Biotechnology. 2014;15(6):583-588.
doi:10.2174/138920101506140910152253 .

Pejin, Boris, Iodice, Carmine, Tommonaro, Giuseppina, Stanimirović, Bojana, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, De Rosa, Salvatore, Soković, Marina, "Further in vitro Evaluation of Antimicrobial Activity of the Marine Sesquiterpene Hydroquinone Avarol" in Current Pharmaceutical Biotechnology, 15, no. 6 (2014):583-588,
https://doi.org/10.2174/138920101506140910152253 . .

TY  - JOUR
AU  - Bukvicki, Danka R
AU  - Stojković, Dejan S
AU  - Soković, Marina
AU  - Vannini, Lucia
AU  - Montanari, Chiara
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Veljic, Milan M
AU  - Grujic, Slavica
AU  - Marin, Petar D.
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/760
AB  - The dominant compounds in Satureja horvatii oil were p-cymene (33.14%), thymol (26.11%) and thymol methyl ether (15.08%). The minimum inhibitory concentration (MIC) varied from 0.03 to 0.57 mg/mL for bacteria, and from 0.56 to 2.23 mg/mL for yeast strains, while minimum bactericidal/yeast-cidal concentration (MBC/MYC) varied from 0.07 to 1.15 mg/mL and 1.11 to 5.57 mg/mL for bacteria and yeasts, respectively. The antiradical potential of the essential oil was evaluated using hydroxyl radical (center dot OH) generated in Fenton reaction. The meat preserving potential of essential oil from Satureja horvatii was investigated against L monocytogenes. Essential oil successfully inhibited development of L monocytogenes in pork meat. Sensorial evaluation on flavor and color of meat was performed. The color and flavor of meat treated with essential oil improved after 4 days of storage. S. horvatii essential oil can act as a potent inhibitor of food spoiling microorganisms, in meat products and also can be a useful source of natural antioxidants.
PB  - Elsevier Sci Ltd, Oxford
T2  - Meat Science
T1  - Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat
EP  - 1360
IS  - 3
SP  - 1355
VL  - 96
DO  - 10.1016/j.meatsci.2013.11.024
ER  - 

@article{
author = "Bukvicki, Danka R and Stojković, Dejan S and Soković, Marina and Vannini, Lucia and Montanari, Chiara and Pejin, Boris and Savić, Aleksandar G and Veljic, Milan M and Grujic, Slavica and Marin, Petar D.",
year = "2014",
abstract = "The dominant compounds in Satureja horvatii oil were p-cymene (33.14%), thymol (26.11%) and thymol methyl ether (15.08%). The minimum inhibitory concentration (MIC) varied from 0.03 to 0.57 mg/mL for bacteria, and from 0.56 to 2.23 mg/mL for yeast strains, while minimum bactericidal/yeast-cidal concentration (MBC/MYC) varied from 0.07 to 1.15 mg/mL and 1.11 to 5.57 mg/mL for bacteria and yeasts, respectively. The antiradical potential of the essential oil was evaluated using hydroxyl radical (center dot OH) generated in Fenton reaction. The meat preserving potential of essential oil from Satureja horvatii was investigated against L monocytogenes. Essential oil successfully inhibited development of L monocytogenes in pork meat. Sensorial evaluation on flavor and color of meat was performed. The color and flavor of meat treated with essential oil improved after 4 days of storage. S. horvatii essential oil can act as a potent inhibitor of food spoiling microorganisms, in meat products and also can be a useful source of natural antioxidants.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Meat Science",
title = "Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat",
pages = "1360-1355",
number = "3",
volume = "96",
doi = "10.1016/j.meatsci.2013.11.024"
}

Bukvicki, D. R., Stojković, D. S., Soković, M., Vannini, L., Montanari, C., Pejin, B., Savić, A. G., Veljic, M. M., Grujic, S.,& Marin, P. D.. (2014). Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. in Meat Science
Elsevier Sci Ltd, Oxford., 96(3), 1355-1360.
https://doi.org/10.1016/j.meatsci.2013.11.024

Bukvicki DR, Stojković DS, Soković M, Vannini L, Montanari C, Pejin B, Savić AG, Veljic MM, Grujic S, Marin PD. Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. in Meat Science. 2014;96(3):1355-1360.
doi:10.1016/j.meatsci.2013.11.024 .

Bukvicki, Danka R, Stojković, Dejan S, Soković, Marina, Vannini, Lucia, Montanari, Chiara, Pejin, Boris, Savić, Aleksandar G, Veljic, Milan M, Grujic, Slavica, Marin, Petar D., "Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat" in Meat Science, 96, no. 3 (2014):1355-1360,
https://doi.org/10.1016/j.meatsci.2013.11.024 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Glamočlija, Jasmina
AU  - Ciric, A.
AU  - Yong, H.-T.
AU  - Soković, Marina
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/639
AB  - The antimicrobial activity of the moss Rhodobryum ontariense tea was evaluated by microdilution method against eight bacterial (Bacillus cereus, Enterobacter cloacae, Escherichia coli, Listeria monocytogens, Micrococcus flavus, Pseudomonas aeruginosa, Salmonella typhimurium and Staphylococcus aureus) and eight fungal species (Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus versicolor, Candida albicans, Penicillium funiculosum, Penicillium ochrochloron and Trichoderma viride). The investigated water extract was proven to be active against all the bacteria and majority of the fungi tested, but to varying degrees. E. cloacae was the most sensitive bacterium (MIC 0.62 mg/mL and MBC 2.50 mg/mL while C. albicans was the most sensitive micro fungus (MIC 0.20 mg/mL and MFC 1.00 mg/mL). On the other hand, at tested concentration the extract did not show any activity against the fungi A. fumigatus and A. niger. These findings indicated a good potential of R. ontariense tea in searching for new antifungals against C. albicans, the fungus which have become a cause of major health concerns in hospital due to hospital-acquired infections.
PB  - Syscom 18 SRL
T2  - Revista de Chimie
T1  - The Moss Rhodobryum ontariense Tea, a Good Source of Natural Antifungals Against Candida albicans
EP  - 554
IS  - 5
SP  - 552
VL  - 64
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_639
ER  - 

@article{
author = "Pejin, Boris and Glamočlija, Jasmina and Ciric, A. and Yong, H.-T. and Soković, Marina",
year = "2013",
abstract = "The antimicrobial activity of the moss Rhodobryum ontariense tea was evaluated by microdilution method against eight bacterial (Bacillus cereus, Enterobacter cloacae, Escherichia coli, Listeria monocytogens, Micrococcus flavus, Pseudomonas aeruginosa, Salmonella typhimurium and Staphylococcus aureus) and eight fungal species (Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus versicolor, Candida albicans, Penicillium funiculosum, Penicillium ochrochloron and Trichoderma viride). The investigated water extract was proven to be active against all the bacteria and majority of the fungi tested, but to varying degrees. E. cloacae was the most sensitive bacterium (MIC 0.62 mg/mL and MBC 2.50 mg/mL while C. albicans was the most sensitive micro fungus (MIC 0.20 mg/mL and MFC 1.00 mg/mL). On the other hand, at tested concentration the extract did not show any activity against the fungi A. fumigatus and A. niger. These findings indicated a good potential of R. ontariense tea in searching for new antifungals against C. albicans, the fungus which have become a cause of major health concerns in hospital due to hospital-acquired infections.",
publisher = "Syscom 18 SRL",
journal = "Revista de Chimie",
title = "The Moss Rhodobryum ontariense Tea, a Good Source of Natural Antifungals Against Candida albicans",
pages = "554-552",
number = "5",
volume = "64",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_639"
}

Pejin, B., Glamočlija, J., Ciric, A., Yong, H.-T.,& Soković, M.. (2013). The Moss Rhodobryum ontariense Tea, a Good Source of Natural Antifungals Against Candida albicans. in Revista de Chimie
Syscom 18 SRL., 64(5), 552-554.
https://hdl.handle.net/21.15107/rcub_rimsi_639

Pejin B, Glamočlija J, Ciric A, Yong H, Soković M. The Moss Rhodobryum ontariense Tea, a Good Source of Natural Antifungals Against Candida albicans. in Revista de Chimie. 2013;64(5):552-554.
https://hdl.handle.net/21.15107/rcub_rimsi_639 .

Pejin, Boris, Glamočlija, Jasmina, Ciric, A., Yong, H.-T., Soković, Marina, "The Moss Rhodobryum ontariense Tea, a Good Source of Natural Antifungals Against Candida albicans" in Revista de Chimie, 64, no. 5 (2013):552-554,
https://hdl.handle.net/21.15107/rcub_rimsi_639 .

TY  - JOUR
AU  - Nikolic, Milos MN
AU  - Marković, Tatjana
AU  - Mojović, Miloš
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Peric, Tamara O
AU  - Marković, Dejan Lj
AU  - Stević, Tatjana R
AU  - Soković, Marina
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/675
AB  - The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops and Products
T1  - Chemical composition and biological activity of Gaultheria procumbens L. essential oil
EP  - 567
SP  - 561
VL  - 49
DO  - 10.1016/j.indcrop.2013.06.002
ER  - 

@article{
author = "Nikolic, Milos MN and Marković, Tatjana and Mojović, Miloš and Pejin, Boris and Savić, Aleksandar G and Peric, Tamara O and Marković, Dejan Lj and Stević, Tatjana R and Soković, Marina",
year = "2013",
abstract = "The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops and Products",
title = "Chemical composition and biological activity of Gaultheria procumbens L. essential oil",
pages = "567-561",
volume = "49",
doi = "10.1016/j.indcrop.2013.06.002"
}

Nikolic, M. M., Marković, T., Mojović, M., Pejin, B., Savić, A. G., Peric, T. O., Marković, D. L., Stević, T. R.,& Soković, M.. (2013). Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products
Elsevier, Amsterdam., 49, 561-567.
https://doi.org/10.1016/j.indcrop.2013.06.002

Nikolic MM, Marković T, Mojović M, Pejin B, Savić AG, Peric TO, Marković DL, Stević TR, Soković M. Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products. 2013;49:561-567.
doi:10.1016/j.indcrop.2013.06.002 .

Nikolic, Milos MN, Marković, Tatjana, Mojović, Miloš, Pejin, Boris, Savić, Aleksandar G, Peric, Tamara O, Marković, Dejan Lj, Stević, Tatjana R, Soković, Marina, "Chemical composition and biological activity of Gaultheria procumbens L. essential oil" in Industrial Crops and Products, 49 (2013):561-567,
https://doi.org/10.1016/j.indcrop.2013.06.002 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Glamočlija, Jasmina
AU  - Ciric, A.
AU  - Radotić, Ksenija
AU  - Vajs, Vlatka E
AU  - Tešević, Vele
AU  - Hegediš, Aleksandar
AU  - Karaman, I.
AU  - Horvatović, Mladen
AU  - Soković, Marina
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/614
AB  - The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).
PB  - Inst Materials Physics
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Antimicrobial activity of the freshwater bryozoan hyalinella punctata (Hancock, 1850)
EP  - 1026
IS  - 3
SP  - 1021
VL  - 7
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1565
ER  - 

@article{
author = "Pejin, Boris and Glamočlija, Jasmina and Ciric, A. and Radotić, Ksenija and Vajs, Vlatka E and Tešević, Vele and Hegediš, Aleksandar and Karaman, I. and Horvatović, Mladen and Soković, Marina",
year = "2012",
abstract = "The antimicrobial activity of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) was tested by microdilution method against eight bacteria and eight fungi for the first time. All five crude extracts (hexane, acetone, dimethyl sulfoxide, methanol and water) showed good antibacterial and antifungal potential in vitro wherein the acetone extract was the most active (MICs 0.50-7.00 mu g/ml and MBCs 2.50-10.00 mu g/ml).",
publisher = "Inst Materials Physics",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Antimicrobial activity of the freshwater bryozoan hyalinella punctata (Hancock, 1850)",
pages = "1026-1021",
number = "3",
volume = "7",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1565"
}

Pejin, B., Glamočlija, J., Ciric, A., Radotić, K., Vajs, V. E., Tešević, V., Hegediš, A., Karaman, I., Horvatović, M.,& Soković, M.. (2012). Antimicrobial activity of the freshwater bryozoan hyalinella punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics., 7(3), 1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565

Pejin B, Glamočlija J, Ciric A, Radotić K, Vajs VE, Tešević V, Hegediš A, Karaman I, Horvatović M, Soković M. Antimicrobial activity of the freshwater bryozoan hyalinella punctata (Hancock, 1850). in Digest Journal of Nanomaterials and Biostructures. 2012;7(3):1021-1026.
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

Pejin, Boris, Glamočlija, Jasmina, Ciric, A., Radotić, Ksenija, Vajs, Vlatka E, Tešević, Vele, Hegediš, Aleksandar, Karaman, I., Horvatović, Mladen, Soković, Marina, "Antimicrobial activity of the freshwater bryozoan hyalinella punctata (Hancock, 1850)" in Digest Journal of Nanomaterials and Biostructures, 7, no. 3 (2012):1021-1026,
https://hdl.handle.net/21.15107/rcub_cherry_1565 .

TY  - JOUR
AU  - Stajic, Mirjana M
AU  - Glamočlija, Jasmina
AU  - Maksimović, Vuk
AU  - Vukojević, Jelena B
AU  - Simonic, Jasmina
AU  - Zervakis, George
PY  - 2011
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/458
AB  - Ganoderma lucidum is a well-known medicinal mushroom species in which polysaccharides are one of the major sources of biological activity. The species was considered as a species-complex due to significant variations in morphological, biochemical, and genetic features among populations with a worldwide distribution. This fact was the basis for setting the aim of this research: to study intraspecific diversity in polysaccharide production and intracellular sugar composition among selected G. lucidum strains. The presence of intraspecific diversity among 10 G. lucidum strains, from different areas worldwide, was noted. Values of produced mycelia biomass and intracellular polysaccharides were found in wide ranges (3.1-28.2 g L-1 and 20.0-53.3 mg g(-1), respectively), while differences in extracellular polysaccharide amounts were minor (0.2-1.5 mg mL(-1)). The significant quantitative and qualitative differences in intracellular sugar composition were noted. Glucose was the predominant sugar in almost all strains except one (HAI 447), where sucrose was dominant. The potential of polysaccharide production and intracellular sugar composition could be one more taxonomic criterion for strain characterization within G. lucidum. The differences in intracellular sugar composition and proportions could be reflected in features of produced polysaccharides and also in their biological activities.
PB  - Begell House Inc, Danbury
T2  - International Journal of Medicinal Mushrooms
T1  - A Comparative Assessment of the Potential of Polysaccharide Production and Intracellular Sugar Composition within Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (Aphyllophoromycetideae)
EP  - 158
IS  - 2
SP  - 153
VL  - 13
DO  - 10.1615/IntJMedMushr.v13.i2.70
ER  - 

@article{
author = "Stajic, Mirjana M and Glamočlija, Jasmina and Maksimović, Vuk and Vukojević, Jelena B and Simonic, Jasmina and Zervakis, George",
year = "2011",
abstract = "Ganoderma lucidum is a well-known medicinal mushroom species in which polysaccharides are one of the major sources of biological activity. The species was considered as a species-complex due to significant variations in morphological, biochemical, and genetic features among populations with a worldwide distribution. This fact was the basis for setting the aim of this research: to study intraspecific diversity in polysaccharide production and intracellular sugar composition among selected G. lucidum strains. The presence of intraspecific diversity among 10 G. lucidum strains, from different areas worldwide, was noted. Values of produced mycelia biomass and intracellular polysaccharides were found in wide ranges (3.1-28.2 g L-1 and 20.0-53.3 mg g(-1), respectively), while differences in extracellular polysaccharide amounts were minor (0.2-1.5 mg mL(-1)). The significant quantitative and qualitative differences in intracellular sugar composition were noted. Glucose was the predominant sugar in almost all strains except one (HAI 447), where sucrose was dominant. The potential of polysaccharide production and intracellular sugar composition could be one more taxonomic criterion for strain characterization within G. lucidum. The differences in intracellular sugar composition and proportions could be reflected in features of produced polysaccharides and also in their biological activities.",
publisher = "Begell House Inc, Danbury",
journal = "International Journal of Medicinal Mushrooms",
title = "A Comparative Assessment of the Potential of Polysaccharide Production and Intracellular Sugar Composition within Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (Aphyllophoromycetideae)",
pages = "158-153",
number = "2",
volume = "13",
doi = "10.1615/IntJMedMushr.v13.i2.70"
}

Stajic, M. M., Glamočlija, J., Maksimović, V., Vukojević, J. B., Simonic, J.,& Zervakis, G.. (2011). A Comparative Assessment of the Potential of Polysaccharide Production and Intracellular Sugar Composition within Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (Aphyllophoromycetideae). in International Journal of Medicinal Mushrooms
Begell House Inc, Danbury., 13(2), 153-158.
https://doi.org/10.1615/IntJMedMushr.v13.i2.70

Stajic MM, Glamočlija J, Maksimović V, Vukojević JB, Simonic J, Zervakis G. A Comparative Assessment of the Potential of Polysaccharide Production and Intracellular Sugar Composition within Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (Aphyllophoromycetideae). in International Journal of Medicinal Mushrooms. 2011;13(2):153-158.
doi:10.1615/IntJMedMushr.v13.i2.70 .

Stajic, Mirjana M, Glamočlija, Jasmina, Maksimović, Vuk, Vukojević, Jelena B, Simonic, Jasmina, Zervakis, George, "A Comparative Assessment of the Potential of Polysaccharide Production and Intracellular Sugar Composition within Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt.:Fr.)P. Karst. (Aphyllophoromycetideae)" in International Journal of Medicinal Mushrooms, 13, no. 2 (2011):153-158,
https://doi.org/10.1615/IntJMedMushr.v13.i2.70 . .