Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro
Nema prikaza
Autori
Pejin, BorisCiric, Ana
Dimitrić-Marković, Jasmina
Glamočlija, Jasmina
Nikolic, Milos
Stanimirović, Bojana
Soković, Marina
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.
Ključne reči:
Pseudomonas aeruginosa PAO1 / Flavonoids / Anti-quorum sensing effects / Anti-biofilm activityIzvor:
Current Pharmaceutical Biotechnology, 2015, 16, 8, 733-737Izdavač:
- Bentham Science Publ Ltd, Sharjah
Finansiranje / projekti:
- Karakterizacija i primena metabolita gljiva i utvrđivanje potencijala novih biofungicida (RS-MESTD-Basic Research (BR or ON)-173032)
- Dinamika nelinearnih fizičkohemijskih i biohemijskih sistema sa modeliranjem i predviđanjem njihovih ponašanja pod neravnotežnim uslovima (RS-MESTD-Basic Research (BR or ON)-172015)
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-MESTD-Basic Research (BR or ON)-172053)
DOI: 10.2174/1389201016666150505121951
ISSN: 1389-2010
PubMed: 25941888
WoS: 000355731400008
Scopus: 2-s2.0-84931826402
Institucija/grupa
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Ciric, Ana AU - Dimitrić-Marković, Jasmina AU - Glamočlija, Jasmina AU - Nikolic, Milos AU - Stanimirović, Bojana AU - Soković, Marina PY - 2015 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/852 AB - This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance. PB - Bentham Science Publ Ltd, Sharjah T2 - Current Pharmaceutical Biotechnology T1 - Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro EP - 737 IS - 8 SP - 733 VL - 16 DO - 10.2174/1389201016666150505121951 ER -
@article{ author = "Pejin, Boris and Ciric, Ana and Dimitrić-Marković, Jasmina and Glamočlija, Jasmina and Nikolic, Milos and Stanimirović, Bojana and Soković, Marina", year = "2015", abstract = "This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.", publisher = "Bentham Science Publ Ltd, Sharjah", journal = "Current Pharmaceutical Biotechnology", title = "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro", pages = "737-733", number = "8", volume = "16", doi = "10.2174/1389201016666150505121951" }
Pejin, B., Ciric, A., Dimitrić-Marković, J., Glamočlija, J., Nikolic, M., Stanimirović, B.,& Soković, M.. (2015). Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology Bentham Science Publ Ltd, Sharjah., 16(8), 733-737. https://doi.org/10.2174/1389201016666150505121951
Pejin B, Ciric A, Dimitrić-Marković J, Glamočlija J, Nikolic M, Stanimirović B, Soković M. Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology. 2015;16(8):733-737. doi:10.2174/1389201016666150505121951 .
Pejin, Boris, Ciric, Ana, Dimitrić-Marković, Jasmina, Glamočlija, Jasmina, Nikolic, Milos, Stanimirović, Bojana, Soković, Marina, "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro" in Current Pharmaceutical Biotechnology, 16, no. 8 (2015):733-737, https://doi.org/10.2174/1389201016666150505121951 . .