Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa
Нема приказа
Аутори
Pejin, BorisTalevska, Aleksandra
Ciric, Ana
Glamočlija, Jasmina
Nikolic, Milos
Talevski, Trajce
Soković, Marina
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching and flagella motility) of two crude extracts (methanol and acetone) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for the first time. Both extracts demonstrated P. aeruginosa pyocyanin inhibitory activity, reducing its production for 49.90% and 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% and 53.99%, respectively) than ampicillin (30.84%). Finally, O. rotunda extracts effectively reduced twitching and flagella motility of P. aeruginosa. Taken all together, these results suggest that endemic sponge species from the oldest lake in Europe may offer novel bioactive natural products with promising medicinal potential towards P. aeruginosa infections.
Кључне речи:
Porifera / Ochridaspongia rotunda / Lake Ohrid / bioactivityИзвор:
Natural Product Research, 2014, 28, 24, 2330-2333Издавач:
- Taylor & Francis Ltd, Abingdon
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-MESTD-Basic Research (BR or ON)-172053)
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-MESTD-Basic Research (BR or ON)-173032)
DOI: 10.1080/14786419.2014.934239
ISSN: 1478-6419
PubMed: 25039944
WoS: 000342326700016
Scopus: 2-s2.0-84908662200
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Talevska, Aleksandra AU - Ciric, Ana AU - Glamočlija, Jasmina AU - Nikolic, Milos AU - Talevski, Trajce AU - Soković, Marina PY - 2014 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/806 AB - The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching and flagella motility) of two crude extracts (methanol and acetone) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for the first time. Both extracts demonstrated P. aeruginosa pyocyanin inhibitory activity, reducing its production for 49.90% and 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% and 53.99%, respectively) than ampicillin (30.84%). Finally, O. rotunda extracts effectively reduced twitching and flagella motility of P. aeruginosa. Taken all together, these results suggest that endemic sponge species from the oldest lake in Europe may offer novel bioactive natural products with promising medicinal potential towards P. aeruginosa infections. PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa EP - 2333 IS - 24 SP - 2330 VL - 28 DO - 10.1080/14786419.2014.934239 ER -
@article{ author = "Pejin, Boris and Talevska, Aleksandra and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and Talevski, Trajce and Soković, Marina", year = "2014", abstract = "The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching and flagella motility) of two crude extracts (methanol and acetone) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for the first time. Both extracts demonstrated P. aeruginosa pyocyanin inhibitory activity, reducing its production for 49.90% and 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% and 53.99%, respectively) than ampicillin (30.84%). Finally, O. rotunda extracts effectively reduced twitching and flagella motility of P. aeruginosa. Taken all together, these results suggest that endemic sponge species from the oldest lake in Europe may offer novel bioactive natural products with promising medicinal potential towards P. aeruginosa infections.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa", pages = "2333-2330", number = "24", volume = "28", doi = "10.1080/14786419.2014.934239" }
Pejin, B., Talevska, A., Ciric, A., Glamočlija, J., Nikolic, M., Talevski, T.,& Soković, M.. (2014). Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa. in Natural Product Research Taylor & Francis Ltd, Abingdon., 28(24), 2330-2333. https://doi.org/10.1080/14786419.2014.934239
Pejin B, Talevska A, Ciric A, Glamočlija J, Nikolic M, Talevski T, Soković M. Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa. in Natural Product Research. 2014;28(24):2330-2333. doi:10.1080/14786419.2014.934239 .
Pejin, Boris, Talevska, Aleksandra, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, Talevski, Trajce, Soković, Marina, "Anti-quorum sensing activity of selected sponge extracts: a case study of Pseudomonas aeruginosa" in Natural Product Research, 28, no. 24 (2014):2330-2333, https://doi.org/10.1080/14786419.2014.934239 . .