Претраживање
Приказ резултата 1-10 од 39
Evaluation of genotoxic potential oftert-butylquinone and its derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2020)
Tert-butylquinone (TBQ) and its alkylamino and aralkylamino derivatives are of high interest as a potential antitumor agent. Therefore, it was necessary to investigate if the compounds exert undesirable activities such as ...
The anthropogenic impact on water quality of the river danube in Serbia: microbiological analysis and genotoxicity monitoring
(Srpsko biološko društvo, Beograd, i dr., 2011)
The aim of this work was to examine the impact of urban wastewaters on the water quality of the Danube River in Serbia. Samples of water and sediments for microbiological analysis and genotoxicity monitoring were collected ...
In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study
(Oxford University Press, 2023)
Environmental studies which aim to assess the ecological impact of chemical and other types of pollution should employ a complex weight-of-evidence approach with multiple lines of evidence (LoEs). This study focused on in ...
In vitro evaluation of cytotoxic and mutagenic activity of avarol
(Taylor & Francis Ltd, Abingdon, 2016)
The cytotoxicity of avarol, a main secondary metabolite of the Mediterranean sponge Dysidea avara, was in vitro screened by MTT assay against four human tumour cell lines. The colon HT-29 tumour cells practically showed ...
Comet assay and cytogenetic findings in differential diagnosis of fanconi anemia
(Društvo genetičara Srbije, Beograd, 2019)
Fanconi anemia (FA) is a complex genetic disease with a variety of congenital and hematological symptoms, including the predisposition for cancer development. The main hallmark of FA cells, an increased chromosomal fragility, ...
Raspberry seeds extract selectively inhibits the growth of human lung cancer cells in vitro
(Taylor & Francis Ltd, Abingdon, 2021)
This study was focused on in vitro cytotoxicity screening of the raspberry seeds methanol extract towards a number of cancer cell lines of human origin. The tested extract at the preferred concentrations (IC50 lt 30 mu ...
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2019)
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3 '-methoxyavarone, 4 '-(methylamino)avarone and 3 '-(methylamino)avarone was evaluated and compared to cytostatics ...
Assesment of genotoxic pollution of the Danube River with comet assay in different tissues of common bream (Abramis brama L. 1758)
(Serbian Genetic Society, Belgrade, Serbia, 2014)
The aim of this study was to assess the genotoxic potential of Danube River at the site Višnjica (downstream Belgrade) on monthly basis over year 2014 in tissues of common bream (A. brama). The level of DNA damage in the ...
Comet assay – a sensitive method for detection DNA damage and primary monitoring of ecosystem pollution pressure
(Institute of Marine Biology, University of Montenegro, 2019)
Untreated municipal wastewaters are one of the major negative contributors on freshwater quality, and consequently on ecosystem balance. Some compounds such as pharmaceuticals, cosmetic products, etc. could be genotoxic ...
Sensitivity of invasive alien fish in Serbia black bullhead Ameiurus melas (Rafinesque, 1820) as a bioindicator of genotoxicity
(EUROPEAN ENVIRONMENTAL MUTAGENESIS & GENOMICS SOCIETY, 2022)
Invasive alien fish species represent one of the greatest threats to the biodiversity and ecological status of freshwater ecosystems. Within their management, their application as bioindicators of pollution in monitoring ...