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Effects of 5-fluorouracil on erythrocytes in relation to its cardiotoxicity: Membrane structure and functioning
(Amer Chemical Soc, Washington, 2005)
In the present study, we showed that the antineoplastic drug 5-fluorouracil (5-FU) induces in vitro exposure-time/dose-dependent changes on the level of an erythrocyte's morphology, ionic balance, and membrane fluidity. ...
P-31 NMR spectroscopy and polarographic combined study of erythrocytes treated with 5-fluorouracil - Cardiotoxicity-related changes in ATP, 2,3-BPG, and O-2 metabolism
(New York Acad Sciences, New York, 2005)
Antineoplastic drug 5-fluorouracil (5-FU) frequently shows cardiotoxic effects, the mechanism of which has not yet been elucidated. The objective of the present study was to explore effects of 5-FU on metabolism of ATP, ...