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Selenotriapine - An isostere of the most studied thiosemicarbazone with pronounced pro-apoptotic activity, low toxicity and ability to challenge phenotype reprogramming of 3-D mammary adenocarcinoma tumors
(Elsevier, Amsterdam, 2020)
Triapine, the most studied alpha-N-heterocyclic thiosemicarbazone, revealed potent activity against advanced leukemia, but was ineffective against a variety of solid tumors. Moreover, methemoglobinemia, which is a side ...
Anti-cancer effects of wedelolactone: interactions with copper and subcellular localization
(Royal Soc Chemistry, Cambridge, 2018)
Wedelactone (WL), a plant polyphenolic derivative of coumestan, represents a promising anti-cancer agent. The underlying mechanisms of its action are not fully understood and appear to involve interplay with copper ions. ...
Electrostatically driven energy shift of molecular orbitals of benzene and nicotine in carbon nanotube gaps
(Springer, Dordrecht, 2021)
The requirement for controllable frontier orbital energy shift in single-molecule devices based on electronic (tunneling) transport yielded several rules for device design that lean on molecular level pinning to the ...
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2019)
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3 '-methoxyavarone, 4 '-(methylamino)avarone and 3 '-(methylamino)avarone was evaluated and compared to cytostatics ...
Silicon acquisition and accumulation in plant and its significance for agriculture
(Elsevier Sci Ltd, Oxford, 2018)
Although silicon (Si) is ubiquitous in soil and plant, evidence is still lacking that Si is essential for higher plants. However, it has been well documented that Si is beneficial for healthy growth of many plant species. ...
Shattering impact fragmentation of slender nanoprojectiles
(Springer, Dordrecht, 2019)
Molecular dynamics simulations of the rigid-anvil collision test are performed to achieve the complete pulverization of slender nanoprojectiles. The simulation setup mimics the traditional Taylor test (the flat-ended ...
Putative targets of direction-selective retinal ganglion cells in the tectum opticum of cyprinid fish
(Elsevier Science Bv, Amsterdam, 2019)
Responses of direction selective (DS) units of retinal and tectal origin were recorded extracellularly from the tectum opticum (TO) of immobilized fish. The data were collected from three cyprinid species - goldfish, carp ...
Structural, Magnetic, DFT, and Biological Studies of Mononuclear and Dinuclear Cu-II Complexes with Bidentate N-Heteroaromatic Schiff Base Ligands
(Wiley-V C H Verlag Gmbh, Weinheim, 2015)
Copper(II) complexes with the condensation derivative of methyl hydrazinoacetate and 2-acetylpyridine were synthesized. The X-ray crystal structures for both complexes revealed that they are polymerized isomers. A common ...
In vitro evaluation of cytotoxic and mutagenic activity of avarol
(Taylor & Francis Ltd, Abingdon, 2016)
The cytotoxicity of avarol, a main secondary metabolite of the Mediterranean sponge Dysidea avara, was in vitro screened by MTT assay against four human tumour cell lines. The colon HT-29 tumour cells practically showed ...
Electrodeposited AgPd alloy coatings as efficient catalysts for the ethanol oxidation reaction
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
The Pd and three AgPd alloy layers (AgPd1, AgPd2 and AgPd3) were electrodeposited onto Au disc electrodes from the solution containing high concentration of chloride ions (>12 M). All coatings were investigated by scanning ...