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Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement
dc.creator | Janjusević, Ljiljana | |
dc.creator | Pejin, Boris | |
dc.creator | Kaisarević, Sonja | |
dc.creator | Gorjanović, Stanislava | |
dc.creator | Pastor, Ferenc | |
dc.creator | Tesanović, Kristina | |
dc.creator | Karaman, Maja | |
dc.date.accessioned | 2022-04-05T15:15:24Z | |
dc.date.available | 2022-04-05T15:15:24Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1478-6419 | |
dc.identifier.uri | http://rimsi.imsi.bg.ac.rs/handle/123456789/1154 | |
dc.description.abstract | This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] . | en |
dc.publisher | Taylor & Francis Ltd, Abingdon | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172058/RS// | |
dc.rights | restrictedAccess | |
dc.source | Natural Product Research | |
dc.subject | Trametes versicolor | en |
dc.subject | hydroxybenzoic acids | en |
dc.subject | ethanol extract | en |
dc.subject | cytotoxic activity | en |
dc.subject | antiradical activity | en |
dc.subject | antioxidant activity | en |
dc.title | Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.epage | 967 | |
dc.citation.issue | 8 | |
dc.citation.other | 32(8): 963-967 | |
dc.citation.rank | M22 | |
dc.citation.spage | 963 | |
dc.citation.volume | 32 | |
dc.identifier.doi | 10.1080/14786419.2017.1366484 | |
dc.identifier.pmid | 28817965 | |
dc.identifier.scopus | 2-s2.0-85027868180 | |
dc.identifier.wos | 000423771400015 | |
dc.type.version | publishedVersion |