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Ekogenotoksikološka procena kvaliteta površinskih voda komet testom na različitim tkivima klena (Squalius cephalus L.) / Ecogenotoxicological evaluation of surface water quality with comet assay on different tissues of european chub (Squalius cephalus L.)
(Univerzitet u Beogradu, Biološki fakultet, 2016)
Intenzivni procesi proizvodnje i oslobađanje velikog broja hemijskih agenasa, kao i metala u spoljašnju sredinu, najvećim delom u rečne tokove, dovela je do potrebe za primenom testova koji će detektovati njihov genotoksični ...
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2019)
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3 '-methoxyavarone, 4 '-(methylamino)avarone and 3 '-(methylamino)avarone was evaluated and compared to cytostatics ...
Comet assay and cytogenetic findings in differential diagnosis of fanconi anemia
(Društvo genetičara Srbije, Beograd, 2019)
Fanconi anemia (FA) is a complex genetic disease with a variety of congenital and hematological symptoms, including the predisposition for cancer development. The main hallmark of FA cells, an increased chromosomal fragility, ...
In vitro evaluation of cytotoxic and mutagenic activity of avarol
(Taylor & Francis Ltd, Abingdon, 2016)
The cytotoxicity of avarol, a main secondary metabolite of the Mediterranean sponge Dysidea avara, was in vitro screened by MTT assay against four human tumour cell lines. The colon HT-29 tumour cells practically showed ...
The anthropogenic impact on water quality of the river danube in Serbia: microbiological analysis and genotoxicity monitoring
(Srpsko biološko društvo, Beograd, i dr., 2011)
The aim of this work was to examine the impact of urban wastewaters on the water quality of the Danube River in Serbia. Samples of water and sediments for microbiological analysis and genotoxicity monitoring were collected ...
Evaluation of genotoxic potential oftert-butylquinone and its derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2020)
Tert-butylquinone (TBQ) and its alkylamino and aralkylamino derivatives are of high interest as a potential antitumor agent. Therefore, it was necessary to investigate if the compounds exert undesirable activities such as ...
In situ detection of the genotoxic potential as one of the lines of evidence in the weight-of-evidence approach—the Joint Danube Survey 4 Case Study
(Oxford University Press, 2023)
Environmental studies which aim to assess the ecological impact of chemical and other types of pollution should employ a complex weight-of-evidence approach with multiple lines of evidence (LoEs). This study focused on in ...
Assesment of genotoxic pollution of the Danube River with comet assay in different tissues of common bream (Abramis brama L. 1758)
(Serbian Genetic Society, Belgrade, Serbia, 2014)
The aim of this study was to assess the genotoxic potential of Danube River at the site Višnjica (downstream Belgrade) on monthly basis over year 2014 in tissues of common bream (A. brama). The level of DNA damage in the ...
Bioassays in assessment of genotoxicity and toxicity of freshwater bodies
(EUROPEAN ENVIRONMENTAL MUTAGENESIS & GENOMICS SOCIETY, 2019)
Untreated urban wastewaters impose high pressure on receiving water bodies. Pollution pressure may triger a cascade of events in exposed organisms, affecting different levels of biological organisation. Fish are a widely ...
Cytostatics as emerging pollutants – is there a threat for aquatic invertebrates?
(University of Agriculture in Krakow, 2018)
Seeking for a better quality of life, consumption of pharmaceuticals is constantly increasing. Pharmaceuticals are designed to be more potent, degradation resistant, to affect protein targets at relatively low doses. Many ...