TY  - JOUR
AU  - Cvetanovic-Zobenica, Katarina
AU  - Lačnjevac, Uroš
AU  - Etinski, Mihajlo
AU  - Vasiljević-Radović, Dana
AU  - Stanisavljev, Dragomir
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1256
AB  - Rising demands for renewable energy sources have led to the development of dye sensitized solar cells. It is a challenge to find a good and low cost sensitizer, which has a low environmental impact. In this work, we conducted spectroscopic and electrochemical experiments, as well as quantum-chemical calculations of the natural pigment hypericin, in order to provide insight into its sensitizing efficiency. To this end, three identical cells were made and characterized. Although this pigment exhibited good adsorption onto a semiconductor surface, a high molar absorption coefficient (43700 L mol(-1) cm(-1)) and favorable alignment of energy levels and provided a long lifetime of electrons (17.8 ms) in the TiO2 photoanode, it was found that the efficiency of hypericin-sensitized solar cells was very low, only 0.0245%. We suggest that this inefficiency originated from a low injection of electrons into the conduction band of TiO2. This conclusion is supported by the density functional theory calculations which revealed a low electron density in the anchoring groups of electronically excited hypericin. The results of this work could be valuable not only in the photovoltaic aspect, but also for application of hypericin in medicine in photodynamic therapy.
PB  - Royal Soc Chemistry, Cambridge
T2  - Photochemical & Photobiological Sciences
T1  - Influence of the electron donor properties of hypericin on its sensitizing ability in DSSCs
EP  - 2030
IS  - 8
SP  - 2023
VL  - 18
DO  - 10.1039/c9pp00188c
ER  - 

@article{
author = "Cvetanovic-Zobenica, Katarina and Lačnjevac, Uroš and Etinski, Mihajlo and Vasiljević-Radović, Dana and Stanisavljev, Dragomir",
year = "2019",
abstract = "Rising demands for renewable energy sources have led to the development of dye sensitized solar cells. It is a challenge to find a good and low cost sensitizer, which has a low environmental impact. In this work, we conducted spectroscopic and electrochemical experiments, as well as quantum-chemical calculations of the natural pigment hypericin, in order to provide insight into its sensitizing efficiency. To this end, three identical cells were made and characterized. Although this pigment exhibited good adsorption onto a semiconductor surface, a high molar absorption coefficient (43700 L mol(-1) cm(-1)) and favorable alignment of energy levels and provided a long lifetime of electrons (17.8 ms) in the TiO2 photoanode, it was found that the efficiency of hypericin-sensitized solar cells was very low, only 0.0245%. We suggest that this inefficiency originated from a low injection of electrons into the conduction band of TiO2. This conclusion is supported by the density functional theory calculations which revealed a low electron density in the anchoring groups of electronically excited hypericin. The results of this work could be valuable not only in the photovoltaic aspect, but also for application of hypericin in medicine in photodynamic therapy.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Photochemical & Photobiological Sciences",
title = "Influence of the electron donor properties of hypericin on its sensitizing ability in DSSCs",
pages = "2030-2023",
number = "8",
volume = "18",
doi = "10.1039/c9pp00188c"
}

Cvetanovic-Zobenica, K., Lačnjevac, U., Etinski, M., Vasiljević-Radović, D.,& Stanisavljev, D.. (2019). Influence of the electron donor properties of hypericin on its sensitizing ability in DSSCs. in Photochemical & Photobiological Sciences
Royal Soc Chemistry, Cambridge., 18(8), 2023-2030.
https://doi.org/10.1039/c9pp00188c

Cvetanovic-Zobenica K, Lačnjevac U, Etinski M, Vasiljević-Radović D, Stanisavljev D. Influence of the electron donor properties of hypericin on its sensitizing ability in DSSCs. in Photochemical & Photobiological Sciences. 2019;18(8):2023-2030.
doi:10.1039/c9pp00188c .

Cvetanovic-Zobenica, Katarina, Lačnjevac, Uroš, Etinski, Mihajlo, Vasiljević-Radović, Dana, Stanisavljev, Dragomir, "Influence of the electron donor properties of hypericin on its sensitizing ability in DSSCs" in Photochemical & Photobiological Sciences, 18, no. 8 (2019):2023-2030,
https://doi.org/10.1039/c9pp00188c . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Dimitrić-Marković, Jasmina
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Soković, Marina
PY  - 2017
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1090
AB  - Anti-biofilm activity of three anthocyanidins (pelargonidin, cyanidin and delphinidin) was evaluated for the first time at in vitro conditions. All the compounds reduced the formation of Pseudomonas aeruginosa PAO1 biofilm at low sub-MIC (0.125 MIC) with delphinidin (c 56.25g/mL) being the most active (43%). In comparison, ampicillin (c 93.75g/mL) and streptomycin (c 21.25g/mL) (used as positive controls) were considerably less effective at the same sub-MIC (8 and 12%, respectively). Furthermore, at 0.5 MIC (c 225g/mL) this anthocyanidin molecule partly reduced the bacterial protrusions. However, no any of the aforementioned compounds inhibited the production of pyocyanin by the bacterial strain P. aeruginosa PAO1. Taken all together, the delphinidin scaffold could be taken into consideration for the design of the novel and more effective anti-biofilm agents inspired by the anthocyanidins.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1
EP  - 1180
IS  - 10
SP  - 1177
VL  - 31
DO  - 10.1080/14786419.2016.1222386
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Dimitrić-Marković, Jasmina and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina",
year = "2017",
abstract = "Anti-biofilm activity of three anthocyanidins (pelargonidin, cyanidin and delphinidin) was evaluated for the first time at in vitro conditions. All the compounds reduced the formation of Pseudomonas aeruginosa PAO1 biofilm at low sub-MIC (0.125 MIC) with delphinidin (c 56.25g/mL) being the most active (43%). In comparison, ampicillin (c 93.75g/mL) and streptomycin (c 21.25g/mL) (used as positive controls) were considerably less effective at the same sub-MIC (8 and 12%, respectively). Furthermore, at 0.5 MIC (c 225g/mL) this anthocyanidin molecule partly reduced the bacterial protrusions. However, no any of the aforementioned compounds inhibited the production of pyocyanin by the bacterial strain P. aeruginosa PAO1. Taken all together, the delphinidin scaffold could be taken into consideration for the design of the novel and more effective anti-biofilm agents inspired by the anthocyanidins.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1",
pages = "1180-1177",
number = "10",
volume = "31",
doi = "10.1080/14786419.2016.1222386"
}

Pejin, B., Ciric, A., Dimitrić-Marković, J., Glamočlija, J., Nikolic, M.,& Soković, M.. (2017). An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 31(10), 1177-1180.
https://doi.org/10.1080/14786419.2016.1222386

Pejin B, Ciric A, Dimitrić-Marković J, Glamočlija J, Nikolic M, Soković M. An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1. in Natural Product Research. 2017;31(10):1177-1180.
doi:10.1080/14786419.2016.1222386 .

Pejin, Boris, Ciric, Ana, Dimitrić-Marković, Jasmina, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "An insight into anti-biofilm and anti-quorum sensing activities of the selected anthocyanidins: the case study of Pseudomonas aeruginosa PAO1" in Natural Product Research, 31, no. 10 (2017):1177-1180,
https://doi.org/10.1080/14786419.2016.1222386 . .

TY  - JOUR
AU  - Dimitrić-Marković, Jasmina
AU  - Pejin, Boris
AU  - Milenković, Dejan
AU  - Amic, Dragan
AU  - Begović, Nebojša
AU  - Mojović, Miloš
AU  - Marković, Zoran S.
PY  - 2017
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1103
AB  - Naturally occurring flavonoids, delphinidin, pelargonidin and malvin, were investigated experimentally and theoretically for their ability to scavenge hydroxyl and nitric oxide radicals. Electron spin resonance (ESR) spectroscopy was used to determine antiradical activity of the selected compounds and M05-2X/6-311+G(d,p) level of theory for the calculation of reaction enthalpies related to three possible mechanisms of free radical scavenging activity, namely HAT, SET-PT and SPLET. The results obtained show that the molecules investigated reacted with hydroxyl radical via both HAT and SPLET in the solvents investigated. These results point to HAT as implausible for the reaction with nitric oxide radical in all the solvents investigated. SET-PT also proved to be thermodynamically unfavourable for all three molecules in the solvents considered.
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms
EP  - 446
SP  - 440
VL  - 218
DO  - 10.1016/j.foodchem.2016.09.106
ER  - 

@article{
author = "Dimitrić-Marković, Jasmina and Pejin, Boris and Milenković, Dejan and Amic, Dragan and Begović, Nebojša and Mojović, Miloš and Marković, Zoran S.",
year = "2017",
abstract = "Naturally occurring flavonoids, delphinidin, pelargonidin and malvin, were investigated experimentally and theoretically for their ability to scavenge hydroxyl and nitric oxide radicals. Electron spin resonance (ESR) spectroscopy was used to determine antiradical activity of the selected compounds and M05-2X/6-311+G(d,p) level of theory for the calculation of reaction enthalpies related to three possible mechanisms of free radical scavenging activity, namely HAT, SET-PT and SPLET. The results obtained show that the molecules investigated reacted with hydroxyl radical via both HAT and SPLET in the solvents investigated. These results point to HAT as implausible for the reaction with nitric oxide radical in all the solvents investigated. SET-PT also proved to be thermodynamically unfavourable for all three molecules in the solvents considered.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms",
pages = "446-440",
volume = "218",
doi = "10.1016/j.foodchem.2016.09.106"
}

Dimitrić-Marković, J., Pejin, B., Milenković, D., Amic, D., Begović, N., Mojović, M.,& Marković, Z. S.. (2017). Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms. in Food Chemistry
Elsevier Sci Ltd, Oxford., 218, 440-446.
https://doi.org/10.1016/j.foodchem.2016.09.106

Dimitrić-Marković J, Pejin B, Milenković D, Amic D, Begović N, Mojović M, Marković ZS. Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms. in Food Chemistry. 2017;218:440-446.
doi:10.1016/j.foodchem.2016.09.106 .

Dimitrić-Marković, Jasmina, Pejin, Boris, Milenković, Dejan, Amic, Dragan, Begović, Nebojša, Mojović, Miloš, Marković, Zoran S., "Antiradical activity of delphinidin, pelargonidin and malvin towards hydroxyl and nitric oxide radicals: The energy requirements calculations as a prediction of the possible antiradical mechanisms" in Food Chemistry, 218 (2017):440-446,
https://doi.org/10.1016/j.foodchem.2016.09.106 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Ciric, Ana
AU  - Dimitrić-Marković, Jasmina
AU  - Glamočlija, Jasmina
AU  - Nikolic, Milos
AU  - Stanimirović, Bojana
AU  - Soković, Marina
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/852
AB  - This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Biotechnology
T1  - Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro
EP  - 737
IS  - 8
SP  - 733
VL  - 16
DO  - 10.2174/1389201016666150505121951
ER  - 

@article{
author = "Pejin, Boris and Ciric, Ana and Dimitrić-Marković, Jasmina and Glamočlija, Jasmina and Nikolic, Milos and Stanimirović, Bojana and Soković, Marina",
year = "2015",
abstract = "This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects of four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin and morin/using the strain Pseudomonas aeruginosa PAO1. At a concentration of 0.5 MIC quercetin was the only compound found to potently reduce both P. aeruginosa biofilm formation (95%) and its twitching motility. The chemical scaffold of quercetin, a common dietary polyphenol, may actually inspire development of novel and more effective medicinal agents targeting P. aeruginosa, the bacterium well known for its resistance.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Biotechnology",
title = "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro",
pages = "737-733",
number = "8",
volume = "16",
doi = "10.2174/1389201016666150505121951"
}

Pejin, B., Ciric, A., Dimitrić-Marković, J., Glamočlija, J., Nikolic, M., Stanimirović, B.,& Soković, M.. (2015). Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology
Bentham Science Publ Ltd, Sharjah., 16(8), 733-737.
https://doi.org/10.2174/1389201016666150505121951

Pejin B, Ciric A, Dimitrić-Marković J, Glamočlija J, Nikolic M, Stanimirović B, Soković M. Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro. in Current Pharmaceutical Biotechnology. 2015;16(8):733-737.
doi:10.2174/1389201016666150505121951 .

Pejin, Boris, Ciric, Ana, Dimitrić-Marković, Jasmina, Glamočlija, Jasmina, Nikolic, Milos, Stanimirović, Bojana, Soković, Marina, "Quercetin Potently Reduces Biofilm Formation of the Strain Pseudomonas aeruginosa PAO1 in vitro" in Current Pharmaceutical Biotechnology, 16, no. 8 (2015):733-737,
https://doi.org/10.2174/1389201016666150505121951 . .