TY  - CONF
AU  - Stojadinović, Gordana
AU  - Yadollahpour, Ali
AU  - Kesić, Srđan Ž.
AU  - Spasić, Slađana
PY  - 2019-07-10
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2467
AB  - Aims: Electroencephalography (EEG) measures could be a potential markers for prediction of repetitive transcranial magnetic stimulation (rTMS) outcomes in depression. The aim of this study was to investigate the value of alpha asymmetric index (AAI) in predicting treatment response in two different protocols of rTMS in patients with intractable major depression. 
Methods: Patients with intractable major depression (n=34) were divided into two treatment groups underwent two different rTMS protocols. The first group  received ten sessions 20 Hz rTMS  The second group received 10 Hz rTMS . The EEGs were recorded in all subjects pre- and post-intervention using a 19-channel, 10-20 electrodes placement protocol. Hamilton depression rating scale-17 items (HDRS-17) was used to divide the patients into responders and non-responder. The AAI in prefrontal (Fp1-Fp2), frontal (F3-F4 and F7-F8), and temporal (T3-T4) regions were calculated and compared between pre- and post-intervention in each group and between the responder and non-responder groups.
Results: In the 20 Hz rTMS group responders, 6 patients responded to the treatment, whereas 10 Hz rTMS showed 8 responders. In the responders of 20 Hz rTMS, the AAI at Fp1-Fp2, F3-F4, and T3-T4significantly decreased after the intervention (P=0.011, P=0.042, and P=0.035). The responders of 10 Hz rTMS showed significant reduction in the AAI at Fp1-Fp2 and T3-T4 regions after intervention (P= 0.023 and P=0.044). 
Conclusions: It seems AAI at prefrontal and temporal region scould be used for prediction of treatment response, regardless of rTMS protocol.
C3  - FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.
T1  - Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2467
ER  - 

@conference{
author = "Stojadinović, Gordana and Yadollahpour, Ali and Kesić, Srđan Ž. and Spasić, Slađana",
year = "2019-07-10",
abstract = "Aims: Electroencephalography (EEG) measures could be a potential markers for prediction of repetitive transcranial magnetic stimulation (rTMS) outcomes in depression. The aim of this study was to investigate the value of alpha asymmetric index (AAI) in predicting treatment response in two different protocols of rTMS in patients with intractable major depression. 
Methods: Patients with intractable major depression (n=34) were divided into two treatment groups underwent two different rTMS protocols. The first group  received ten sessions 20 Hz rTMS  The second group received 10 Hz rTMS . The EEGs were recorded in all subjects pre- and post-intervention using a 19-channel, 10-20 electrodes placement protocol. Hamilton depression rating scale-17 items (HDRS-17) was used to divide the patients into responders and non-responder. The AAI in prefrontal (Fp1-Fp2), frontal (F3-F4 and F7-F8), and temporal (T3-T4) regions were calculated and compared between pre- and post-intervention in each group and between the responder and non-responder groups.
Results: In the 20 Hz rTMS group responders, 6 patients responded to the treatment, whereas 10 Hz rTMS showed 8 responders. In the responders of 20 Hz rTMS, the AAI at Fp1-Fp2, F3-F4, and T3-T4significantly decreased after the intervention (P=0.011, P=0.042, and P=0.035). The responders of 10 Hz rTMS showed significant reduction in the AAI at Fp1-Fp2 and T3-T4 regions after intervention (P= 0.023 and P=0.044). 
Conclusions: It seems AAI at prefrontal and temporal region scould be used for prediction of treatment response, regardless of rTMS protocol.",
journal = "FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.",
title = "Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2467"
}

Stojadinović, G., Yadollahpour, A., Kesić, S. Ž.,& Spasić, S.. (2019-07-10). Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609..
https://hdl.handle.net/21.15107/rcub_rimsi_2467

Stojadinović G, Yadollahpour A, Kesić SŽ, Spasić S. Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.. 2019;.
https://hdl.handle.net/21.15107/rcub_rimsi_2467 .

Stojadinović, Gordana, Yadollahpour, Ali, Kesić, Srđan Ž., Spasić, Slađana, "Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation" in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609. (2019-07-10),
https://hdl.handle.net/21.15107/rcub_rimsi_2467 .

TY  - CONF
AU  - Kesić, Srđan Ž.
AU  - Yadollahpour, Ali
AU  - Riahi, F.
AU  - Naraghi, M.
AU  - Stojadinović, Gordana
AU  - Spasić, Slađana
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2383
AB  - Background and Aims: Neurofeedback treatment (NFT) may enhance attention performance in healthy individuals. This study investigated the effects of single session NFT on attention in healthy individuals performing a visual attention task. 
Methods: This was an open-label single-blinded trial conducted on 14 healthy university students (n=14; mean=23.35±0.58 years) of a major medical university in Iran. The subjects underwent a single session NFT while performing attentional network task (ANT). The NFT protocol was theta suppression/beta-1enhancement applied at Cz for 20 min. Before and immediately after NFT, EEG signals were recorded in subjects while performing ANT. EEGs were recorded using a 19 channel device and 10-20 placement protocol.
Results: The single session NFT increased the theta/beta-1 ratio in most of the electrode sites and the increase was statistically significant compared to the pre-intervention in the T6 site (p=0.011). The ratio decreased in just three sites of C3, Fz, and Cz, of them Fz showed a significant reduction (p=0.026). Contrary, the theta/alpha ratio decreased in most of the electrodes where the reductions were statistically significant in P3, P4, Cz, Pz (p<0.05), and C3 (p<0.01). The F7, F8, T3, and T4 showed no significant increased theta/alpha ratio. The central, temporal and occipital regions were involved in the NFT induced changes. Single NFT did not significantly change alerting, executive, or orienting networks of ANT.
Conclusions: Theta/beta-1 and theta/alpha ratios can be reliably used to assess NFT induced attention enhancement. However, single NFT did not induce clinical outcomes and repeated sessions seem necessary to modulate alerting, executive, or orienting networks of ANT.
C3  - FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369
T1  - Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention
IS  - 369
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2383
ER  - 

@conference{
author = "Kesić, Srđan Ž. and Yadollahpour, Ali and Riahi, F. and Naraghi, M. and Stojadinović, Gordana and Spasić, Slađana",
year = "2019",
abstract = "Background and Aims: Neurofeedback treatment (NFT) may enhance attention performance in healthy individuals. This study investigated the effects of single session NFT on attention in healthy individuals performing a visual attention task. 
Methods: This was an open-label single-blinded trial conducted on 14 healthy university students (n=14; mean=23.35±0.58 years) of a major medical university in Iran. The subjects underwent a single session NFT while performing attentional network task (ANT). The NFT protocol was theta suppression/beta-1enhancement applied at Cz for 20 min. Before and immediately after NFT, EEG signals were recorded in subjects while performing ANT. EEGs were recorded using a 19 channel device and 10-20 placement protocol.
Results: The single session NFT increased the theta/beta-1 ratio in most of the electrode sites and the increase was statistically significant compared to the pre-intervention in the T6 site (p=0.011). The ratio decreased in just three sites of C3, Fz, and Cz, of them Fz showed a significant reduction (p=0.026). Contrary, the theta/alpha ratio decreased in most of the electrodes where the reductions were statistically significant in P3, P4, Cz, Pz (p<0.05), and C3 (p<0.01). The F7, F8, T3, and T4 showed no significant increased theta/alpha ratio. The central, temporal and occipital regions were involved in the NFT induced changes. Single NFT did not significantly change alerting, executive, or orienting networks of ANT.
Conclusions: Theta/beta-1 and theta/alpha ratios can be reliably used to assess NFT induced attention enhancement. However, single NFT did not induce clinical outcomes and repeated sessions seem necessary to modulate alerting, executive, or orienting networks of ANT.",
journal = "FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369",
title = "Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention",
number = "369",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2383"
}

Kesić, S. Ž., Yadollahpour, A., Riahi, F., Naraghi, M., Stojadinović, G.,& Spasić, S.. (2019). Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369(369).
https://hdl.handle.net/21.15107/rcub_rimsi_2383

Kesić SŽ, Yadollahpour A, Riahi F, Naraghi M, Stojadinović G, Spasić S. Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369. 2019;(369).
https://hdl.handle.net/21.15107/rcub_rimsi_2383 .

Kesić, Srđan Ž., Yadollahpour, Ali, Riahi, F., Naraghi, M., Stojadinović, Gordana, Spasić, Slađana, "Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention" in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369, no. 369 (2019),
https://hdl.handle.net/21.15107/rcub_rimsi_2383 .

TY  - BOOK
AU  - Spasić, Slađana
AU  - Kesić, Srđan Ž.
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2839
PB  - Frontiers Media SA.
T2  - Frontiers in Phyiology: Fractal Physiology
T1  - Nonlinearity in Living Systems: Theoretical and Practical Perspectives on Metrics of Physiological Signal Complexity
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2839
ER  - 

@book{
author = "Spasić, Slađana and Kesić, Srđan Ž.",
year = "2019",
publisher = "Frontiers Media SA.",
journal = "Frontiers in Phyiology: Fractal Physiology",
title = "Nonlinearity in Living Systems: Theoretical and Practical Perspectives on Metrics of Physiological Signal Complexity",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2839"
}

Spasić, S.,& Kesić, S. Ž.. (2019). Nonlinearity in Living Systems: Theoretical and Practical Perspectives on Metrics of Physiological Signal Complexity. in Frontiers in Phyiology: Fractal Physiology
Frontiers Media SA...
https://hdl.handle.net/21.15107/rcub_rimsi_2839

Spasić S, Kesić SŽ. Nonlinearity in Living Systems: Theoretical and Practical Perspectives on Metrics of Physiological Signal Complexity. in Frontiers in Phyiology: Fractal Physiology. 2019;.
https://hdl.handle.net/21.15107/rcub_rimsi_2839 .

Spasić, Slađana, Kesić, Srđan Ž., "Nonlinearity in Living Systems: Theoretical and Practical Perspectives on Metrics of Physiological Signal Complexity" in Frontiers in Phyiology: Fractal Physiology (2019),
https://hdl.handle.net/21.15107/rcub_rimsi_2839 .

TY  - CONF
AU  - Kesić, Srđan Ž.
AU  - Spasić, Slađana
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2402
PB  - Srpsko biološko društvo
C3  - DRUGI KONGRES BIOLOGA SRBIJE osnovna i primenjena istraživanja metodika nastave KNJIGA SAŽETAKA, Kladovo (Usmeno izlaganje)
T1  - Higučijeva fraktalna dimenzija u analizi fizioloških signala: od matematičke teorije do biološke prakse
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2402
ER  - 

@conference{
author = "Kesić, Srđan Ž. and Spasić, Slađana",
year = "2018",
publisher = "Srpsko biološko društvo",
journal = "DRUGI KONGRES BIOLOGA SRBIJE osnovna i primenjena istraživanja metodika nastave KNJIGA SAŽETAKA, Kladovo (Usmeno izlaganje)",
title = "Higučijeva fraktalna dimenzija u analizi fizioloških signala: od matematičke teorije do biološke prakse",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2402"
}

Kesić, S. Ž.,& Spasić, S.. (2018). Higučijeva fraktalna dimenzija u analizi fizioloških signala: od matematičke teorije do biološke prakse. in DRUGI KONGRES BIOLOGA SRBIJE osnovna i primenjena istraživanja metodika nastave KNJIGA SAŽETAKA, Kladovo (Usmeno izlaganje)
Srpsko biološko društvo..
https://hdl.handle.net/21.15107/rcub_rimsi_2402

Kesić SŽ, Spasić S. Higučijeva fraktalna dimenzija u analizi fizioloških signala: od matematičke teorije do biološke prakse. in DRUGI KONGRES BIOLOGA SRBIJE osnovna i primenjena istraživanja metodika nastave KNJIGA SAŽETAKA, Kladovo (Usmeno izlaganje). 2018;.
https://hdl.handle.net/21.15107/rcub_rimsi_2402 .

Kesić, Srđan Ž., Spasić, Slađana, "Higučijeva fraktalna dimenzija u analizi fizioloških signala: od matematičke teorije do biološke prakse" in DRUGI KONGRES BIOLOGA SRBIJE osnovna i primenjena istraživanja metodika nastave KNJIGA SAŽETAKA, Kladovo (Usmeno izlaganje) (2018),
https://hdl.handle.net/21.15107/rcub_rimsi_2402 .

TY  - CONF
AU  - Kesić, Srđan Ž.
AU  - Spasić, Slađana
AU  - Stojadinović, Gordana
AU  - Petković, Branka
AU  - Todorović, Dajana
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2388
PB  - Belgrade: Serbian Physiological Society
C3  - 3rd Congress of Physiological Sciences of Serbia With International Participation
T1  - Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2388
ER  - 

@conference{
author = "Kesić, Srđan Ž. and Spasić, Slađana and Stojadinović, Gordana and Petković, Branka and Todorović, Dajana",
year = "2014",
publisher = "Belgrade: Serbian Physiological Society",
journal = "3rd Congress of Physiological Sciences of Serbia With International Participation",
title = "Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2388"
}

Kesić, S. Ž., Spasić, S., Stojadinović, G., Petković, B.,& Todorović, D.. (2014). Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe. in 3rd Congress of Physiological Sciences of Serbia With International Participation
Belgrade: Serbian Physiological Society..
https://hdl.handle.net/21.15107/rcub_rimsi_2388

Kesić SŽ, Spasić S, Stojadinović G, Petković B, Todorović D. Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe. in 3rd Congress of Physiological Sciences of Serbia With International Participation. 2014;.
https://hdl.handle.net/21.15107/rcub_rimsi_2388 .

Kesić, Srđan Ž., Spasić, Slađana, Stojadinović, Gordana, Petković, Branka, Todorović, Dajana, "Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe" in 3rd Congress of Physiological Sciences of Serbia With International Participation (2014),
https://hdl.handle.net/21.15107/rcub_rimsi_2388 .

TY  - JOUR
AU  - Kesić, Srđan Ž.
AU  - Nikolić, Ljiljana
AU  - Janać, Branka
AU  - Spasić, Slađana
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2398
AB  - The components of complex bioelectrical activity – action potential (AP), interspike interval (ISI) and the quiet interburst interval (IBI), along with the effects of 2.7 mT and 10 mT static magnetic fields, were identified and examined in the spontaneously active Br neuron of the subesophageal ganglion complex of the garden snail Helix pomatia by fractal analysis using Higuchi’s fractal dimension (FD). The normalized mean of the empirical FD distributions of bursting activity of the Br neuron were formed under different experimental conditions: before (Control), during (MF), and after exposure to the static magnetic field (AMF). Using the fractal analysis method for the first time, a separation of the AP, ISI and IBI components was successfully achieved. Our results show that fractal analysis with deconvolution of the normalized mean of the empirical FD distributions into Gaussian functions is a useful tool for revealing the effects of magnetic fields on the complexity of neuronal bioelectric activity and its AP, ISI and IBI components.
PB  - Serbian Biological Society
PB  - Institute for Biological Research "Siniša Stanković", Serbia
PB  - Serbian Biological Society, Institute for BFaculty of Biology, University of Belgrade
PB  - Department of Biology and Ecology, Faculty of Science, University of Novi Sad
PB  - Institute for the Application of Nuclear Energy
T2  - Archives of Biological Sciences
T1  - Using Higuchi’s fractal dimension in fine analysis of the effects of 2.7 mT and 10 mT static magnetic fields on the complex bursting activity of the snail BR neuron
EP  - 572
IS  - 2
SP  - 563
VL  - 66
DO  - 10.2298/ABS1402563K
ER  - 

@article{
author = "Kesić, Srđan Ž. and Nikolić, Ljiljana and Janać, Branka and Spasić, Slađana",
year = "2014",
abstract = "The components of complex bioelectrical activity – action potential (AP), interspike interval (ISI) and the quiet interburst interval (IBI), along with the effects of 2.7 mT and 10 mT static magnetic fields, were identified and examined in the spontaneously active Br neuron of the subesophageal ganglion complex of the garden snail Helix pomatia by fractal analysis using Higuchi’s fractal dimension (FD). The normalized mean of the empirical FD distributions of bursting activity of the Br neuron were formed under different experimental conditions: before (Control), during (MF), and after exposure to the static magnetic field (AMF). Using the fractal analysis method for the first time, a separation of the AP, ISI and IBI components was successfully achieved. Our results show that fractal analysis with deconvolution of the normalized mean of the empirical FD distributions into Gaussian functions is a useful tool for revealing the effects of magnetic fields on the complexity of neuronal bioelectric activity and its AP, ISI and IBI components.",
publisher = "Serbian Biological Society, Institute for Biological Research "Siniša Stanković", Serbia, Serbian Biological Society, Institute for BFaculty of Biology, University of Belgrade, Department of Biology and Ecology, Faculty of Science, University of Novi Sad, Institute for the Application of Nuclear Energy",
journal = "Archives of Biological Sciences",
title = "Using Higuchi’s fractal dimension in fine analysis of the effects of 2.7 mT and 10 mT static magnetic fields on the complex bursting activity of the snail BR neuron",
pages = "572-563",
number = "2",
volume = "66",
doi = "10.2298/ABS1402563K"
}

Kesić, S. Ž., Nikolić, L., Janać, B.,& Spasić, S.. (2014). Using Higuchi’s fractal dimension in fine analysis of the effects of 2.7 mT and 10 mT static magnetic fields on the complex bursting activity of the snail BR neuron. in Archives of Biological Sciences
Serbian Biological Society., 66(2), 563-572.
https://doi.org/10.2298/ABS1402563K

Kesić SŽ, Nikolić L, Janać B, Spasić S. Using Higuchi’s fractal dimension in fine analysis of the effects of 2.7 mT and 10 mT static magnetic fields on the complex bursting activity of the snail BR neuron. in Archives of Biological Sciences. 2014;66(2):563-572.
doi:10.2298/ABS1402563K .

Kesić, Srđan Ž., Nikolić, Ljiljana, Janać, Branka, Spasić, Slađana, "Using Higuchi’s fractal dimension in fine analysis of the effects of 2.7 mT and 10 mT static magnetic fields on the complex bursting activity of the snail BR neuron" in Archives of Biological Sciences, 66, no. 2 (2014):563-572,
https://doi.org/10.2298/ABS1402563K . .

TY  - JOUR
AU  - Grbić, Gordana
AU  - Ćulić, Milka
AU  - Martać, Ljiljana
AU  - Kesić, Srđan Ž.
AU  - Soković, Marina
AU  - Spasić, Slađana
AU  - Đoković, Dejan
PY  - 2006
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2945
AB  - We have decided to detect the seizure brain activity induced by camphor essential oil in rats, as there are still reports of severe intoxication in humans by camphor. The experiments were performed on adult Wistar male rats. The surgery and the acute electrophysiological recordings were done under pentobarbital sodium anesthesia. Local field potentials of cerebral parietal cortex were recorded. The rats were injected by camphor essential oil (150-675 μl/kg b.w., in 1 ml of saline, i.p). We analyzed by Fast Fourier Transform the digitized electrocortical signals before and up 2-3 h after essential oil administration at the sampling rate of 256 Hz. There was a great increase of the mean total power spectra, a relative increase of the power in delta range and decreases of theta and beta ranges when seizural activity with spikes and waves of large amplitude occurred at the level of cerebral cortex 5-30 min after administration of camphor oil at doses >300 μl/kg b.w. It is necessary to investigate further the dose dependent effectiveness of each terpenoid constituent of camphor essential oil on brain activity in order to elucidate the relative safety of the usage of essential oils with these terpenoids.
PB  - Serbian Union of Biological Sciences
T2  - Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica
T1  - Trovanje kamforom - spektralna analiza aktivnosti mozga pacova
T1  - Camphor oil poisoning: Spectral analysis of rat brain activity
EP  - 238
IS  - 3
SP  - 233
VL  - 42
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2945
ER  - 

@article{
author = "Grbić, Gordana and Ćulić, Milka and Martać, Ljiljana and Kesić, Srđan Ž. and Soković, Marina and Spasić, Slađana and Đoković, Dejan",
year = "2006",
abstract = "We have decided to detect the seizure brain activity induced by camphor essential oil in rats, as there are still reports of severe intoxication in humans by camphor. The experiments were performed on adult Wistar male rats. The surgery and the acute electrophysiological recordings were done under pentobarbital sodium anesthesia. Local field potentials of cerebral parietal cortex were recorded. The rats were injected by camphor essential oil (150-675 μl/kg b.w., in 1 ml of saline, i.p). We analyzed by Fast Fourier Transform the digitized electrocortical signals before and up 2-3 h after essential oil administration at the sampling rate of 256 Hz. There was a great increase of the mean total power spectra, a relative increase of the power in delta range and decreases of theta and beta ranges when seizural activity with spikes and waves of large amplitude occurred at the level of cerebral cortex 5-30 min after administration of camphor oil at doses >300 μl/kg b.w. It is necessary to investigate further the dose dependent effectiveness of each terpenoid constituent of camphor essential oil on brain activity in order to elucidate the relative safety of the usage of essential oils with these terpenoids.",
publisher = "Serbian Union of Biological Sciences",
journal = "Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica",
title = "Trovanje kamforom - spektralna analiza aktivnosti mozga pacova, Camphor oil poisoning: Spectral analysis of rat brain activity",
pages = "238-233",
number = "3",
volume = "42",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2945"
}

Grbić, G., Ćulić, M., Martać, L., Kesić, S. Ž., Soković, M., Spasić, S.,& Đoković, D.. (2006). Trovanje kamforom - spektralna analiza aktivnosti mozga pacova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica
Serbian Union of Biological Sciences., 42(3), 233-238.
https://hdl.handle.net/21.15107/rcub_rimsi_2945

Grbić G, Ćulić M, Martać L, Kesić SŽ, Soković M, Spasić S, Đoković D. Trovanje kamforom - spektralna analiza aktivnosti mozga pacova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica. 2006;42(3):233-238.
https://hdl.handle.net/21.15107/rcub_rimsi_2945 .

Grbić, Gordana, Ćulić, Milka, Martać, Ljiljana, Kesić, Srđan Ž., Soković, Marina, Spasić, Slađana, Đoković, Dejan, "Trovanje kamforom - spektralna analiza aktivnosti mozga pacova" in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica, 42, no. 3 (2006):233-238,
https://hdl.handle.net/21.15107/rcub_rimsi_2945 .

TY  - JOUR
AU  - Martać, Ljiljana
AU  - Kesić, Srđan Ž.
AU  - Ćulić, Milka
AU  - Grbić, Gordana
AU  - Spasić, Slađana
AU  - Sekulić, Slobodan
AU  - Lalošević, Dušan
PY  - 2006
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2877
AB  - The aim of our study was to investigate the electrophysiological effects of aluminium neurotoxicity. This animal model of neurodegenerative dementia was induced by chronic treatment of Wistarrats with aluminum chloride for 4 weeks - 2mg Al/kg, i.p, per day. Electrophysiological recordings of left and right somatosensory cortical areas of animals treated by aluminium and the control rats were done under Nembutal anesthesia. Analog to the digital one conversion of the recorded signals was performed at the sampling rate of 256 Hz. Spectral analysis of electrocortical activity during sequences of 120 s (divided in epochs of 8s) was obtained by Fast Fourier Transformation while fractal dimension (FD) of these signals was calculated by Higuchi's algorithm. The relative power spectra of cerebral activity were increased in delta frequency range and decreased in (8.1-32.0 Hz) range in aluminium treated animals compared to the controls. The average fractal dimension of electrocortical activity in aluminium treated animals was lower - 1.290 than the average fractal dimension of electrocortical activity in the control rats - 1.377. Spectral and fractal characteristics of brain activity could bean electrophysiological sign of developing neurodegenerative process similar to the Alzheimer's dementia.
T2  - Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica
T1  - Efekat neurotoksičnosti aluminijuma na elektrokortikalnu aktivnost mozga pacova
T1  - Effect of aluminium neurotoxicity on the rat brain electrocortical activity
EP  - 225
IS  - 3
SP  - 219
VL  - 42
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2877
ER  - 

@article{
author = "Martać, Ljiljana and Kesić, Srđan Ž. and Ćulić, Milka and Grbić, Gordana and Spasić, Slađana and Sekulić, Slobodan and Lalošević, Dušan",
year = "2006",
abstract = "The aim of our study was to investigate the electrophysiological effects of aluminium neurotoxicity. This animal model of neurodegenerative dementia was induced by chronic treatment of Wistarrats with aluminum chloride for 4 weeks - 2mg Al/kg, i.p, per day. Electrophysiological recordings of left and right somatosensory cortical areas of animals treated by aluminium and the control rats were done under Nembutal anesthesia. Analog to the digital one conversion of the recorded signals was performed at the sampling rate of 256 Hz. Spectral analysis of electrocortical activity during sequences of 120 s (divided in epochs of 8s) was obtained by Fast Fourier Transformation while fractal dimension (FD) of these signals was calculated by Higuchi's algorithm. The relative power spectra of cerebral activity were increased in delta frequency range and decreased in (8.1-32.0 Hz) range in aluminium treated animals compared to the controls. The average fractal dimension of electrocortical activity in aluminium treated animals was lower - 1.290 than the average fractal dimension of electrocortical activity in the control rats - 1.377. Spectral and fractal characteristics of brain activity could bean electrophysiological sign of developing neurodegenerative process similar to the Alzheimer's dementia.",
journal = "Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica",
title = "Efekat neurotoksičnosti aluminijuma na elektrokortikalnu aktivnost mozga pacova, Effect of aluminium neurotoxicity on the rat brain electrocortical activity",
pages = "225-219",
number = "3",
volume = "42",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2877"
}

Martać, L., Kesić, S. Ž., Ćulić, M., Grbić, G., Spasić, S., Sekulić, S.,& Lalošević, D.. (2006). Efekat neurotoksičnosti aluminijuma na elektrokortikalnu aktivnost mozga pacova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica, 42(3), 219-225.
https://hdl.handle.net/21.15107/rcub_rimsi_2877

Martać L, Kesić SŽ, Ćulić M, Grbić G, Spasić S, Sekulić S, Lalošević D. Efekat neurotoksičnosti aluminijuma na elektrokortikalnu aktivnost mozga pacova. in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica. 2006;42(3):219-225.
https://hdl.handle.net/21.15107/rcub_rimsi_2877 .

Martać, Ljiljana, Kesić, Srđan Ž., Ćulić, Milka, Grbić, Gordana, Spasić, Slađana, Sekulić, Slobodan, Lalošević, Dušan, "Efekat neurotoksičnosti aluminijuma na elektrokortikalnu aktivnost mozga pacova" in Acta biologica serbica - serija C: Acta physiologica et pharmacologica serbica, 42, no. 3 (2006):219-225,
https://hdl.handle.net/21.15107/rcub_rimsi_2877 .