In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1
Нема приказа
Аутори
Pejin, BorisCiric, Ana
Karaman, Ivo
Horvatović, Mladen
Glamočlija, Jasmina
Nikolic, Milos
Soković, Marina
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The antibiofilm and possible antiquorum sensing effects against the strain Pseudomonas aeruginosa PAO1 of five crude extracts of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) were evaluated in vitro for the first time. H. punctata ethyl acetate extract (HpEtAc) exhibited the highest antibiofilm activity reducing the biofilm formation of P. aeruginosa PAO1 in the range of 80.63-88.13%. While all tested extracts reduced the twitching motility of the aforementioned bacterial strain, HpEtAc showed to be the most effective. Finally, at a concentration of 0.5 MIC, the same extract mostly inhibited the production of pyocyanin by P. aeruginosa PAO1 (71.53%). In comparison both with the positive controls used (streptomycin and ampicillin, 67.13 and 69.77%, respectively), HpEtAc was found to inhibit pyocyanin in a higher extent. An extensive chemical characterisation of this particular extract may result in isolation and identification of novel lead compounds targeting P. aeruginos...a, an opportunistic human pathogen. [GRAPHCIS].
Кључне речи:
extracts / Bryozoa / antiquorum sensing activity / antibiofilm activityИзвор:
Natural Product Research, 2016, 30, 16, 1847-1850Издавач:
- Taylor & Francis Ltd, Abingdon
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-MESTD-Basic Research (BR or ON)-172053)
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-MESTD-Basic Research (BR or ON)-173032)
DOI: 10.1080/14786419.2015.1072714
ISSN: 1478-6419
PubMed: 26264659
WoS: 000382554700012
Scopus: 2-s2.0-84939180206
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Ciric, Ana AU - Karaman, Ivo AU - Horvatović, Mladen AU - Glamočlija, Jasmina AU - Nikolic, Milos AU - Soković, Marina PY - 2016 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/954 AB - The antibiofilm and possible antiquorum sensing effects against the strain Pseudomonas aeruginosa PAO1 of five crude extracts of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) were evaluated in vitro for the first time. H. punctata ethyl acetate extract (HpEtAc) exhibited the highest antibiofilm activity reducing the biofilm formation of P. aeruginosa PAO1 in the range of 80.63-88.13%. While all tested extracts reduced the twitching motility of the aforementioned bacterial strain, HpEtAc showed to be the most effective. Finally, at a concentration of 0.5 MIC, the same extract mostly inhibited the production of pyocyanin by P. aeruginosa PAO1 (71.53%). In comparison both with the positive controls used (streptomycin and ampicillin, 67.13 and 69.77%, respectively), HpEtAc was found to inhibit pyocyanin in a higher extent. An extensive chemical characterisation of this particular extract may result in isolation and identification of novel lead compounds targeting P. aeruginosa, an opportunistic human pathogen. [GRAPHCIS]. PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1 EP - 1850 IS - 16 SP - 1847 VL - 30 DO - 10.1080/14786419.2015.1072714 ER -
@article{ author = "Pejin, Boris and Ciric, Ana and Karaman, Ivo and Horvatović, Mladen and Glamočlija, Jasmina and Nikolic, Milos and Soković, Marina", year = "2016", abstract = "The antibiofilm and possible antiquorum sensing effects against the strain Pseudomonas aeruginosa PAO1 of five crude extracts of the freshwater bryozoan Hyalinella punctata (Hancock, 1850) were evaluated in vitro for the first time. H. punctata ethyl acetate extract (HpEtAc) exhibited the highest antibiofilm activity reducing the biofilm formation of P. aeruginosa PAO1 in the range of 80.63-88.13%. While all tested extracts reduced the twitching motility of the aforementioned bacterial strain, HpEtAc showed to be the most effective. Finally, at a concentration of 0.5 MIC, the same extract mostly inhibited the production of pyocyanin by P. aeruginosa PAO1 (71.53%). In comparison both with the positive controls used (streptomycin and ampicillin, 67.13 and 69.77%, respectively), HpEtAc was found to inhibit pyocyanin in a higher extent. An extensive chemical characterisation of this particular extract may result in isolation and identification of novel lead compounds targeting P. aeruginosa, an opportunistic human pathogen. [GRAPHCIS].", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1", pages = "1850-1847", number = "16", volume = "30", doi = "10.1080/14786419.2015.1072714" }
Pejin, B., Ciric, A., Karaman, I., Horvatović, M., Glamočlija, J., Nikolic, M.,& Soković, M.. (2016). In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1. in Natural Product Research Taylor & Francis Ltd, Abingdon., 30(16), 1847-1850. https://doi.org/10.1080/14786419.2015.1072714
Pejin B, Ciric A, Karaman I, Horvatović M, Glamočlija J, Nikolic M, Soković M. In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1. in Natural Product Research. 2016;30(16):1847-1850. doi:10.1080/14786419.2015.1072714 .
Pejin, Boris, Ciric, Ana, Karaman, Ivo, Horvatović, Mladen, Glamočlija, Jasmina, Nikolic, Milos, Soković, Marina, "In vitro antibiofilm activity of the freshwater bryozoan Hyalinella punctata: a case study of Pseudomonas aeruginosa PAO1" in Natural Product Research, 30, no. 16 (2016):1847-1850, https://doi.org/10.1080/14786419.2015.1072714 . .