Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin
Само за регистроване кориснике
2016
Чланак у часопису (Објављена верзија)

Метаподаци
Приказ свих података о документуАпстракт
Catechins are transformed into dinitrosocatechins (diNOcats) and then oxidized to the quinones by salivary nitrite under conditions simulating the stomach. This manuscript deals with formation of stable radicals in the NO group of diNOcat during nitrite-induced oxidation of (+)-catechin and diNOcat at pH 2. We postulated two mechanisms for the stable radical formation; one is nitrous acid-induced oxidation of diNOcat in the A-ring, and the other intermolecular charge transfer from the A-ring of diNOcat and/or diNOcat quinone to the quinone moiety of the B-ring of diNOcat quinone. In addition, an unstable phenoxyl radical, which might be transformed into quinone, was also produced, accompanying the formation of the stable radical on the NO group. Taking the above results into account, we mainly focus on the adverse effects of the radicals and quinone, which may be produced from (+)-catechin in the stomach under the conditions of high salivary nitrite concentrations.
Кључне речи:
Stomach / Nitroxyl radical / Nitrous acid / Charge transfer complex / 6,8-Dinitrosocatechin / (+)-CatechinИзвор:
Food Chemistry, 2016, 194, 1116-1122Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Kyushu Dental University
- Модификације антиоксидативног метаболизма биљака са циљем повећања толеранције на абиотски стрес и идентификација нових биомаркера са применом у ремедијацији и мониторингу деградираних станишта (RS-43010)
DOI: 10.1016/j.foodchem.2015.08.081
ISSN: 0308-8146
PubMed: 26471661
WoS: 000364248900143
Scopus: 2-s2.0-84940922086
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Morina, Filis AU - Takahama, Umeo AU - Mojović, Miloš AU - Popovic-Bijelic, Ana AU - Veljović-Jovanović, Sonja PY - 2016 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/939 AB - Catechins are transformed into dinitrosocatechins (diNOcats) and then oxidized to the quinones by salivary nitrite under conditions simulating the stomach. This manuscript deals with formation of stable radicals in the NO group of diNOcat during nitrite-induced oxidation of (+)-catechin and diNOcat at pH 2. We postulated two mechanisms for the stable radical formation; one is nitrous acid-induced oxidation of diNOcat in the A-ring, and the other intermolecular charge transfer from the A-ring of diNOcat and/or diNOcat quinone to the quinone moiety of the B-ring of diNOcat quinone. In addition, an unstable phenoxyl radical, which might be transformed into quinone, was also produced, accompanying the formation of the stable radical on the NO group. Taking the above results into account, we mainly focus on the adverse effects of the radicals and quinone, which may be produced from (+)-catechin in the stomach under the conditions of high salivary nitrite concentrations. PB - Elsevier Sci Ltd, Oxford T2 - Food Chemistry T1 - Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin EP - 1122 SP - 1116 VL - 194 DO - 10.1016/j.foodchem.2015.08.081 ER -
@article{ author = "Morina, Filis and Takahama, Umeo and Mojović, Miloš and Popovic-Bijelic, Ana and Veljović-Jovanović, Sonja", year = "2016", abstract = "Catechins are transformed into dinitrosocatechins (diNOcats) and then oxidized to the quinones by salivary nitrite under conditions simulating the stomach. This manuscript deals with formation of stable radicals in the NO group of diNOcat during nitrite-induced oxidation of (+)-catechin and diNOcat at pH 2. We postulated two mechanisms for the stable radical formation; one is nitrous acid-induced oxidation of diNOcat in the A-ring, and the other intermolecular charge transfer from the A-ring of diNOcat and/or diNOcat quinone to the quinone moiety of the B-ring of diNOcat quinone. In addition, an unstable phenoxyl radical, which might be transformed into quinone, was also produced, accompanying the formation of the stable radical on the NO group. Taking the above results into account, we mainly focus on the adverse effects of the radicals and quinone, which may be produced from (+)-catechin in the stomach under the conditions of high salivary nitrite concentrations.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Food Chemistry", title = "Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin", pages = "1122-1116", volume = "194", doi = "10.1016/j.foodchem.2015.08.081" }
Morina, F., Takahama, U., Mojović, M., Popovic-Bijelic, A.,& Veljović-Jovanović, S.. (2016). Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin. in Food Chemistry Elsevier Sci Ltd, Oxford., 194, 1116-1122. https://doi.org/10.1016/j.foodchem.2015.08.081
Morina F, Takahama U, Mojović M, Popovic-Bijelic A, Veljović-Jovanović S. Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin. in Food Chemistry. 2016;194:1116-1122. doi:10.1016/j.foodchem.2015.08.081 .
Morina, Filis, Takahama, Umeo, Mojović, Miloš, Popovic-Bijelic, Ana, Veljović-Jovanović, Sonja, "Formation of stable radicals in catechin/nitrous acid systems: Participation of dinitrosocatechin" in Food Chemistry, 194 (2016):1116-1122, https://doi.org/10.1016/j.foodchem.2015.08.081 . .