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dc.creatorStanić, Marina
dc.creatorZivić, Miroslav
dc.creatorHadzibrahimović, Mirzeta
dc.creatorPajdic, Aleksandra
dc.creatorKrizak, Strahinja
dc.creatorŽižić, Milan
dc.creatorZakrzewska, Joanna
dc.date.accessioned2022-04-05T14:52:18Z
dc.date.available2022-04-05T14:52:18Z
dc.date.issued2014
dc.identifier.issn0354-4664
dc.identifier.urihttp://rimsi.imsi.bg.ac.rs/handle/123456789/809
dc.description.abstractThe effects of long-term exposure (5 h) of Phycomyces blakesleeanus mycelium to 5 mM KCN on respiration and phosphate metabolites were tested. Exposure to cyanide, antimycin A and azide lead to a decrease in the activity of cyanide-sensitive respiration (CSR), and the ratio of core polyphosphates (PPc) and inorganic phosphates (Pi), which is a good indicator of the metabolic state of a cell. After 5 h of incubation, the activity of CSR returned to control values. For this, the recovery of cytochrome c oxid.ase (COX) was required. In addition, the PPc/Pi ratio started to recover shortly after initiation of COX recovery, but never reached control values. This led us to conclude that the regulation of polyphosphate (PPn) levels in the cell is tightly coupled to respiratory chain functioning. In addition, acutely applied cyanide caused two different responses, observed by P-31 NMR spectroscopy, that were probably mediated through the mechanism of glycolytic oscillations, triggered by the effect of cyanide on mitochondria.en
dc.publisherSrpsko biološko društvo, Beograd, i dr.
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173040/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceArchives of Biological Sciences
dc.subjectsugar phosphatesen
dc.subjectpolyphosphatesen
dc.subjectPhycomyces blakesleeanusen
dc.subjectP-31 NMRen
dc.subjectcyanide sensitive respirationen
dc.titleEffect of long-term cyanide exposure on cyanide-sensitive respiration and phosphate metabolism in the fungus phycomyces blakesleeanusen
dc.typearticle
dc.rights.licenseBY-NC-ND
dc.citation.epage857
dc.citation.issue2
dc.citation.other66(2): 847-857
dc.citation.rankM23
dc.citation.spage847
dc.citation.volume66
dc.identifier.doi10.2298/ABS1402847S
dc.identifier.fulltexthttp://rimsi.imsi.bg.ac.rs/bitstream/id/968/806.pdf
dc.identifier.scopus2-s2.0-84904015691
dc.identifier.wos000342265800044
dc.type.versionpublishedVersion


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Приказ основних података о документу