A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

2013
Authors
Pejin, Boris
Tommonaro, Giuseppina

Iodice, Carmine
Tešević, Vele

Vajs, Vlatka E
De Rosa, Salvatore
Article (Published version)
Metadata
Show full item recordAbstract
The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.
Keywords:
secondary metabolite / Lichen / biological activitySource:
Journal of Enzyme Inhibition and Medicinal Chemistry, 2013, 28, 4, 876-878Publisher:
- Informa Healthcare, London
Funding / projects:
- Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-172053)
- The membranes as sites of interaction between the intracellular and apoplastic environments: studies of the bioenergetics and signaling using biophysical and biochemical techniques. (RS-173040)
DOI: 10.3109/14756366.2012.677839
ISSN: 1475-6366
PubMed: 22512723
WoS: 000321693400030
Scopus: 2-s2.0-84869076601
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Institution/Community
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Tommonaro, Giuseppina AU - Iodice, Carmine AU - Tešević, Vele AU - Vajs, Vlatka E AU - De Rosa, Salvatore PY - 2013 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/660 AB - The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors. PB - Informa Healthcare, London T2 - Journal of Enzyme Inhibition and Medicinal Chemistry T1 - A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity EP - 878 IS - 4 SP - 876 VL - 28 DO - 10.3109/14756366.2012.677839 ER -
@article{ author = "Pejin, Boris and Tommonaro, Giuseppina and Iodice, Carmine and Tešević, Vele and Vajs, Vlatka E and De Rosa, Salvatore", year = "2013", abstract = "The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.", publisher = "Informa Healthcare, London", journal = "Journal of Enzyme Inhibition and Medicinal Chemistry", title = "A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity", pages = "878-876", number = "4", volume = "28", doi = "10.3109/14756366.2012.677839" }
Pejin, B., Tommonaro, G., Iodice, C., Tešević, V., Vajs, V. E.,& De Rosa, S.. (2013). A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity. in Journal of Enzyme Inhibition and Medicinal Chemistry Informa Healthcare, London., 28(4), 876-878. https://doi.org/10.3109/14756366.2012.677839
Pejin B, Tommonaro G, Iodice C, Tešević V, Vajs VE, De Rosa S. A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity. in Journal of Enzyme Inhibition and Medicinal Chemistry. 2013;28(4):876-878. doi:10.3109/14756366.2012.677839 .
Pejin, Boris, Tommonaro, Giuseppina, Iodice, Carmine, Tešević, Vele, Vajs, Vlatka E, De Rosa, Salvatore, "A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity" in Journal of Enzyme Inhibition and Medicinal Chemistry, 28, no. 4 (2013):876-878, https://doi.org/10.3109/14756366.2012.677839 . .