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A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

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2013
657.pdf (822.7Kb)
Authors
Pejin, Boris
Tommonaro, Giuseppina
Iodice, Carmine
Tešević, Vele
Vajs, Vlatka E
De Rosa, Salvatore
Article (Published version)
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Abstract
The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.
Keywords:
secondary metabolite / Lichen / biological activity
Source:
Journal of Enzyme Inhibition and Medicinal Chemistry, 2013, 28, 4, 876-878
Publisher:
  • Informa Healthcare, London
Funding / projects:
  • Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-172053)
  • The membranes as sites of interaction between the intracellular and apoplastic environments: studies of the bioenergetics and signaling using biophysical and biochemical techniques. (RS-173040)

DOI: 10.3109/14756366.2012.677839

ISSN: 1475-6366

PubMed: 22512723

WoS: 000321693400030

Scopus: 2-s2.0-84869076601
[ Google Scholar ]
21
15
URI
http://rimsi.imsi.bg.ac.rs/handle/123456789/660
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Institut za multidisciplinarna istraživanja
TY  - JOUR
AU  - Pejin, Boris
AU  - Tommonaro, Giuseppina
AU  - Iodice, Carmine
AU  - Tešević, Vele
AU  - Vajs, Vlatka E
AU  - De Rosa, Salvatore
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/660
AB  - The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.
PB  - Informa Healthcare, London
T2  - Journal of Enzyme Inhibition and Medicinal Chemistry
T1  - A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity
EP  - 878
IS  - 4
SP  - 876
VL  - 28
DO  - 10.3109/14756366.2012.677839
ER  - 
@article{
author = "Pejin, Boris and Tommonaro, Giuseppina and Iodice, Carmine and Tešević, Vele and Vajs, Vlatka E and De Rosa, Salvatore",
year = "2013",
abstract = "The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.",
publisher = "Informa Healthcare, London",
journal = "Journal of Enzyme Inhibition and Medicinal Chemistry",
title = "A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity",
pages = "878-876",
number = "4",
volume = "28",
doi = "10.3109/14756366.2012.677839"
}
Pejin, B., Tommonaro, G., Iodice, C., Tešević, V., Vajs, V. E.,& De Rosa, S.. (2013). A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity. in Journal of Enzyme Inhibition and Medicinal Chemistry
Informa Healthcare, London., 28(4), 876-878.
https://doi.org/10.3109/14756366.2012.677839
Pejin B, Tommonaro G, Iodice C, Tešević V, Vajs VE, De Rosa S. A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity. in Journal of Enzyme Inhibition and Medicinal Chemistry. 2013;28(4):876-878.
doi:10.3109/14756366.2012.677839 .
Pejin, Boris, Tommonaro, Giuseppina, Iodice, Carmine, Tešević, Vele, Vajs, Vlatka E, De Rosa, Salvatore, "A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity" in Journal of Enzyme Inhibition and Medicinal Chemistry, 28, no. 4 (2013):876-878,
https://doi.org/10.3109/14756366.2012.677839 . .

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