Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode
Само за регистроване кориснике
2012
Аутори
Stoiljković, Z.Z.Avramov-Ivić, Milka L
Petrović, S.D.
Mijin, Dušan
Stevanović, Sanja I.
Lačnjevac, Uroš
Marinković, Aleksandar
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The oxidative behaviour of amlodipine besylate was studied. The gold electrode and Au/o-MWCNT (oxidized multi-wall carbon nanotubes) were used for determination of amlodipine besylate standard and as a content of Alopres tablet, in 0.05 M NaHCO3 and in phosphate buffer (pH=11) by cyclic voltammetry and square-wave anodic stripping voltammetry. Electrode surfaces were characterized by AFM in the presence of amlodipine and the concentrations of drugs in electrolytes were simultaneously followed by HPLC. The linear dependency of the anodic currents of amlodipine besylate as standard and in Alopres tablet vs. concentration was observed in both electrolytes, but in phosphate buffer for the higher concentrations. The peak currents obtained in all experiments are more than fifty-fold higher comparing to all previously published results concerning the glassy carbon electrode and the carbon paste electrode. The gold electrode is better catalyst for anodic oxidation of amlodipine besylate than g...lassy carbone. The results obtained with Au/o-MWCNT show lower anodic activity comparing to previously published GC/o-MWCNT. GC/o-MWCNT is better catalyst than Au/o-MWCNT under similar experimental conditions.
Кључне речи:
o-MWCNT / gold electrode / atomic force microscopy / amlodipineИзвор:
International Journal of Electrochemical Science, 2012, 7, 3, 2288-2303Издавач:
- Electrochemical Science Group, Beograd
Финансирање / пројекти:
- Проучавање синтезе, структуре и активности органских једињења природног и синтетског порекла (RS-MESTD-Basic Research (BR or ON)-172013)
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Stoiljković, Z.Z. AU - Avramov-Ivić, Milka L AU - Petrović, S.D. AU - Mijin, Dušan AU - Stevanović, Sanja I. AU - Lačnjevac, Uroš AU - Marinković, Aleksandar PY - 2012 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/610 AB - The oxidative behaviour of amlodipine besylate was studied. The gold electrode and Au/o-MWCNT (oxidized multi-wall carbon nanotubes) were used for determination of amlodipine besylate standard and as a content of Alopres tablet, in 0.05 M NaHCO3 and in phosphate buffer (pH=11) by cyclic voltammetry and square-wave anodic stripping voltammetry. Electrode surfaces were characterized by AFM in the presence of amlodipine and the concentrations of drugs in electrolytes were simultaneously followed by HPLC. The linear dependency of the anodic currents of amlodipine besylate as standard and in Alopres tablet vs. concentration was observed in both electrolytes, but in phosphate buffer for the higher concentrations. The peak currents obtained in all experiments are more than fifty-fold higher comparing to all previously published results concerning the glassy carbon electrode and the carbon paste electrode. The gold electrode is better catalyst for anodic oxidation of amlodipine besylate than glassy carbone. The results obtained with Au/o-MWCNT show lower anodic activity comparing to previously published GC/o-MWCNT. GC/o-MWCNT is better catalyst than Au/o-MWCNT under similar experimental conditions. PB - Electrochemical Science Group, Beograd T2 - International Journal of Electrochemical Science T1 - Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode EP - 2303 IS - 3 SP - 2288 VL - 7 UR - https://hdl.handle.net/21.15107/rcub_cer_1019 ER -
@article{ author = "Stoiljković, Z.Z. and Avramov-Ivić, Milka L and Petrović, S.D. and Mijin, Dušan and Stevanović, Sanja I. and Lačnjevac, Uroš and Marinković, Aleksandar", year = "2012", abstract = "The oxidative behaviour of amlodipine besylate was studied. The gold electrode and Au/o-MWCNT (oxidized multi-wall carbon nanotubes) were used for determination of amlodipine besylate standard and as a content of Alopres tablet, in 0.05 M NaHCO3 and in phosphate buffer (pH=11) by cyclic voltammetry and square-wave anodic stripping voltammetry. Electrode surfaces were characterized by AFM in the presence of amlodipine and the concentrations of drugs in electrolytes were simultaneously followed by HPLC. The linear dependency of the anodic currents of amlodipine besylate as standard and in Alopres tablet vs. concentration was observed in both electrolytes, but in phosphate buffer for the higher concentrations. The peak currents obtained in all experiments are more than fifty-fold higher comparing to all previously published results concerning the glassy carbon electrode and the carbon paste electrode. The gold electrode is better catalyst for anodic oxidation of amlodipine besylate than glassy carbone. The results obtained with Au/o-MWCNT show lower anodic activity comparing to previously published GC/o-MWCNT. GC/o-MWCNT is better catalyst than Au/o-MWCNT under similar experimental conditions.", publisher = "Electrochemical Science Group, Beograd", journal = "International Journal of Electrochemical Science", title = "Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode", pages = "2303-2288", number = "3", volume = "7", url = "https://hdl.handle.net/21.15107/rcub_cer_1019" }
Stoiljković, Z.Z., Avramov-Ivić, M. L., Petrović, S.D., Mijin, D., Stevanović, S. I., Lačnjevac, U.,& Marinković, A.. (2012). Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode. in International Journal of Electrochemical Science Electrochemical Science Group, Beograd., 7(3), 2288-2303. https://hdl.handle.net/21.15107/rcub_cer_1019
Stoiljković Z, Avramov-Ivić ML, Petrović S, Mijin D, Stevanović SI, Lačnjevac U, Marinković A. Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode. in International Journal of Electrochemical Science. 2012;7(3):2288-2303. https://hdl.handle.net/21.15107/rcub_cer_1019 .
Stoiljković, Z.Z., Avramov-Ivić, Milka L, Petrović, S.D., Mijin, Dušan, Stevanović, Sanja I., Lačnjevac, Uroš, Marinković, Aleksandar, "Voltammetric and Square-Wave Anodic Stripping Determination of Amlodipine Besylate on Gold Electrode" in International Journal of Electrochemical Science, 7, no. 3 (2012):2288-2303, https://hdl.handle.net/21.15107/rcub_cer_1019 .