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Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria

Authorized Users Only
2012
Authors
Pejin, Boris
Tommonaro, Giuseppina
Iodice, Carmine
Tešević, Vele
Vajs, Vlatka E
Article (Published version)
Metadata
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Abstract
A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease.
Keywords:
Phytochemistry / Lobariaceae / Depsidones / Alzheimer's disease
Source:
Asian Journal of Chemistry, 2012, 24, 7, 3261-3262
Publisher:
  • Asian Journal Of Chemistry, Sahibabad
Funding / projects:
  • Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-172053)

ISSN: 0970-7077

WoS: 000305034100107

[ Google Scholar ]
2
Handle
https://hdl.handle.net/21.15107/rcub_cherry_1306
URI
http://rimsi.imsi.bg.ac.rs/handle/123456789/538
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Institut za multidisciplinarna istraživanja
TY  - JOUR
AU  - Pejin, Boris
AU  - Tommonaro, Giuseppina
AU  - Iodice, Carmine
AU  - Tešević, Vele
AU  - Vajs, Vlatka E
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/538
AB  - A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease.
PB  - Asian Journal Of Chemistry, Sahibabad
T2  - Asian Journal of Chemistry
T1  - Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria
EP  - 3262
IS  - 7
SP  - 3261
VL  - 24
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1306
ER  - 
@article{
author = "Pejin, Boris and Tommonaro, Giuseppina and Iodice, Carmine and Tešević, Vele and Vajs, Vlatka E",
year = "2012",
abstract = "A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease.",
publisher = "Asian Journal Of Chemistry, Sahibabad",
journal = "Asian Journal of Chemistry",
title = "Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria",
pages = "3262-3261",
number = "7",
volume = "24",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1306"
}
Pejin, B., Tommonaro, G., Iodice, C., Tešević, V.,& Vajs, V. E.. (2012). Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria. in Asian Journal of Chemistry
Asian Journal Of Chemistry, Sahibabad., 24(7), 3261-3262.
https://hdl.handle.net/21.15107/rcub_cherry_1306
Pejin B, Tommonaro G, Iodice C, Tešević V, Vajs VE. Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria. in Asian Journal of Chemistry. 2012;24(7):3261-3262.
https://hdl.handle.net/21.15107/rcub_cherry_1306 .
Pejin, Boris, Tommonaro, Giuseppina, Iodice, Carmine, Tešević, Vele, Vajs, Vlatka E, "Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria" in Asian Journal of Chemistry, 24, no. 7 (2012):3261-3262,
https://hdl.handle.net/21.15107/rcub_cherry_1306 .

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