Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes
Abstract
The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intraperitoneal administration of camphor essential oil (450-675 mu l/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of ictal ECoG sequences were lower than those before camphor oil administration.
Keywords:
seizure / rats / fractal dimension / electrocortical activity / Camphor oilSource:
Archives of Biological Sciences, 2008, 60, 4, 547-553Publisher:
- Srpsko biološko društvo, Beograd, i dr.
Funding / projects:
- Efekti traumatskih, neurotoksičnih i neuroprotektivnih faktora na električnu aktivnost mozga sisara. Analiza i modeliranje (RS-143021)
- Institute for Medicinal Plant Research Belgrade
DOI: 10.2298/ABS0804547G
ISSN: 0354-4664
WoS: 000262112000006
Scopus: 2-s2.0-57749107422
Collections
Institution/Community
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Grbic, G. AU - Culic, M. AU - Martać, Ljiljana AU - Soković, Marina AU - Spasić, Slađana AU - Doković, D. PY - 2008 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/239 AB - The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intraperitoneal administration of camphor essential oil (450-675 mu l/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of ictal ECoG sequences were lower than those before camphor oil administration. PB - Srpsko biološko društvo, Beograd, i dr. T2 - Archives of Biological Sciences T1 - Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes EP - 553 IS - 4 SP - 547 VL - 60 DO - 10.2298/ABS0804547G ER -
@article{ author = "Grbic, G. and Culic, M. and Martać, Ljiljana and Soković, Marina and Spasić, Slađana and Doković, D.", year = "2008", abstract = "The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intraperitoneal administration of camphor essential oil (450-675 mu l/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of ictal ECoG sequences were lower than those before camphor oil administration.", publisher = "Srpsko biološko društvo, Beograd, i dr.", journal = "Archives of Biological Sciences", title = "Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes", pages = "553-547", number = "4", volume = "60", doi = "10.2298/ABS0804547G" }
Grbic, G., Culic, M., Martać, L., Soković, M., Spasić, S.,& Doković, D.. (2008). Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes. in Archives of Biological Sciences Srpsko biološko društvo, Beograd, i dr.., 60(4), 547-553. https://doi.org/10.2298/ABS0804547G
Grbic G, Culic M, Martać L, Soković M, Spasić S, Doković D. Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes. in Archives of Biological Sciences. 2008;60(4):547-553. doi:10.2298/ABS0804547G .
Grbic, G., Culic, M., Martać, Ljiljana, Soković, Marina, Spasić, Slađana, Doković, D., "Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes" in Archives of Biological Sciences, 60, no. 4 (2008):547-553, https://doi.org/10.2298/ABS0804547G . .