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Effect of ethyl pyruvate on central nervous system inflammation
(Elsevier Science Bv, Amsterdam, 2014)
The ongoing success of dimethyl fumarate (DMF; Tecfidera) opens a perspective for further development of the redox strategy in multiple sclerosis (MS) treatment. The mechanisms of anti-inflammatory and neuroprotective ...
A Comparative Analysis of Multiple Sclerosis-Relevant Anti-Inflammatory Properties of Ethyl Pyruvate and Dimethyl Fumarate
(Amer Assoc Immunologists, Bethesda, 2015)
Dimethyl fumarate (DMF), a new drug for multiple sclerosis (MS) treatment, acts against neuroinflammation via mechanisms that are triggered by adduct formation with thiol redox switches. Ethyl pyruvate (EP), an off-the-shelf ...