CeO2 (nanoceria) is the most important rare-earth oxide and potent free radical scavenger, due to coexistence of Ce3+ and Ce4+ ions and formation of oxygen vacancies on its surface. These nanoparticles can collect reactive oxygen species (ROS) and protect healthy cells from oxidative stress, but they also show cytotoxicity. This dual behavior of nanoceria represents a great pharmacological potential, such as improving the treatment of cancers, drug delivery and catalysis. We established the method for synthesizing these nanoparticles, which was particularly challenging because of their low solubility. To facilitate nanoparticle’s entry into the cells, we further coated these nanoparticles with the addition of carbohydrate (glucose, levan or pullulan) in the reaction mixture during and after the synthesis of nanoceria. We investigated by which of two applied methods of synthesis gave more soluble ceria nanoparticles.
TY - CONF
AU - Milenković, Ivana
AU - Radotić, Ksenija
AU - Matović, Branko
PY - 2015
UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/1826
AB - CeO2 (nanoceria) is the most important rare-earth oxide and potent free radical scavenger, due to coexistence of Ce3+ and Ce4+ ions and formation of oxygen vacancies on its surface. These nanoparticles can collect reactive oxygen species (ROS) and protect healthy cells from oxidative stress, but they also show cytotoxicity. This dual behavior of nanoceria represents a great pharmacological potential, such as improving the treatment of cancers, drug delivery and catalysis. We established the method for synthesizing these nanoparticles, which was particularly challenging because of their low solubility. To facilitate nanoparticle’s entry into the cells, we further coated these nanoparticles with the addition of carbohydrate (glucose, levan or pullulan) in the reaction mixture during and after the synthesis of nanoceria. We investigated by which of two applied methods of synthesis gave more soluble ceria nanoparticles.
PB - Scientific association for development and affirmation of new technologies
C3 - 2nd International Conference ’’Modern methods of testing and evaluation in science’’
T1 - The methods for nanoceria’s coating in order to improve its solubility
SP - 208
UR - https://hdl.handle.net/21.15107/rcub_rimsi_1826
ER -
@conference{
author = "Milenković, Ivana and Radotić, Ksenija and Matović, Branko",
year = "2015",
abstract = "CeO2 (nanoceria) is the most important rare-earth oxide and potent free radical scavenger, due to coexistence of Ce3+ and Ce4+ ions and formation of oxygen vacancies on its surface. These nanoparticles can collect reactive oxygen species (ROS) and protect healthy cells from oxidative stress, but they also show cytotoxicity. This dual behavior of nanoceria represents a great pharmacological potential, such as improving the treatment of cancers, drug delivery and catalysis. We established the method for synthesizing these nanoparticles, which was particularly challenging because of their low solubility. To facilitate nanoparticle’s entry into the cells, we further coated these nanoparticles with the addition of carbohydrate (glucose, levan or pullulan) in the reaction mixture during and after the synthesis of nanoceria. We investigated by which of two applied methods of synthesis gave more soluble ceria nanoparticles.",
publisher = "Scientific association for development and affirmation of new technologies",
journal = "2nd International Conference ’’Modern methods of testing and evaluation in science’’",
title = "The methods for nanoceria’s coating in order to improve its solubility",
pages = "208",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_1826"
}
Milenković, I., Radotić, K.,& Matović, B.. (2015). The methods for nanoceria’s coating in order to improve its solubility. in 2nd International Conference ’’Modern methods of testing and evaluation in science’’
Scientific association for development and affirmation of new technologies., 208.
https://hdl.handle.net/21.15107/rcub_rimsi_1826
Milenković I, Radotić K, Matović B. The methods for nanoceria’s coating in order to improve its solubility. in 2nd International Conference ’’Modern methods of testing and evaluation in science’’. 2015;:208.
https://hdl.handle.net/21.15107/rcub_rimsi_1826 .
Milenković, Ivana, Radotić, Ksenija, Matović, Branko, "The methods for nanoceria’s coating in order to improve its solubility" in 2nd International Conference ’’Modern methods of testing and evaluation in science’’ (2015):208,
https://hdl.handle.net/21.15107/rcub_rimsi_1826 .
