dc.creator | Spasojević, Dragica | |
dc.creator | Mutavdžić, Dragosav | |
dc.creator | Simonović Radosavljević, Jasna | |
dc.creator | Mitrović, Aleksandra Lj. | |
dc.creator | Đikanović, Daniela | |
dc.creator | Radotić, Ksenija | |
dc.date.accessioned | 2023-03-01T10:25:19Z | |
dc.date.available | 2023-03-01T10:25:19Z | |
dc.date.issued | 2022 | |
dc.identifier.isbn | 978-86-82475-41-5 | |
dc.identifier.uri | http://rimsi.imsi.bg.ac.rs/handle/123456789/1749 | |
dc.description.abstract | Controlled drug delivery systems are of great interest in modern science and medicine. This study was oriented towards encapsulation of synthetic lignin (DHP) into alginate beads and investigation of its release kinetic. Encapsulation was achieved by the ionotropic gelation method. In vitro release profiles were fitted into four release kinetic models (zero-order, first-order, Higuchi, and Korsmeyer-Peppas). According to the in vitro release, data alginate beads showed initial burst release followed by prolonged release. The best correlation was found for the Korsmeyer-Peppas model (R2 = 0.948), with an n value lower than 0.43, indicating the DHP transport mechanism was controlled by quasi-Fickian diffusion. This delivery system could be promising for chronic wound care and antibacterial treatment. | sr |
dc.language.iso | en | sr |
dc.publisher | Society of Physical Chemists of Serbia | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200053/RS// | sr |
dc.rights | closedAccess | sr |
dc.source | 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry | sr |
dc.subject | synthetic lignin | sr |
dc.subject | alginate beads | sr |
dc.subject | kinetic models | sr |
dc.title | KINETIC RELEASE STUDY OF SYNTHETIC LIGNIN (DHP) FROM CALCIUM ALGINATE BEADS | sr |
dc.type | conferenceObject | sr |
dc.rights.license | ARR | sr |
dc.citation.volume | 2 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_rimsi_1749 | |
dc.type.version | publishedVersion | sr |