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dc.creatorWillaert, Ronnie
dc.creatorVanden, Boer, Pieterjan
dc.creatorMalovichko, Anton
dc.creatorAlioscha-Perez, Mitchel
dc.creatorRadotić, Ksenija
dc.creatorBartolić, Dragana
dc.creatorKalauzi, Aleksandar
dc.creatorVillalba, Maria Ines
dc.creatorSanglard, Dominique
dc.creatorDietler, Giovanni
dc.creatorSahli, Hichem
dc.creatorKasas, Sandor
dc.date.accessioned2022-04-05T15:27:24Z
dc.date.available2022-04-05T15:27:24Z
dc.date.issued2020
dc.identifier.issn2375-2548
dc.identifier.urihttp://rimsi.imsi.bg.ac.rs/handle/123456789/1335
dc.description.abstractLiving single yeast cells show a specific cellular motion at the nanometer scale with a magnitude that is proportional to the cellular activity of the cell. We characterized this cellular nanomotion pattern of nonattached single yeast cells using classical optical microscopy. The distribution of the cellular displacements over a short time period is distinct from random motion. The range and shape of such nanomotion displacement distributions change substantially according to the metabolic state of the cell. The analysis of the nanomotion frequency pattern demonstrated that single living yeast cells oscillate at relatively low frequencies of around 2 hertz. The simplicity of the technique should open the way to numerous applications among which antifungal susceptibility tests seem the most straightforward.en
dc.publisherAmer Assoc Advancement Science, Washington
dc.relationBelgian Federal Science Policy Office (Belspo)Belgian Federal Science Policy Office
dc.relationEuropean Space Agency (ESA) PRODEX program (Yeast Bioreactor project)
dc.relationResearch Council of the Vrije Universiteit Brussel (Belgium) support the International Joint Research Group (IJRG) VUB-EPFL BioNanotechnology & NanoMedicine (NANO) and the Strategic Research Program [SRP11-M3D2]
dc.relationSwiss National Grants [200021-144321, 407240-167137, CRSII5_173863]
dc.relationGebert Ruf Stiftung [GRS-024/14]
dc.relationNASANational Aeronautics & Space Administration (NASA) [NNH16ZDA001N-CLDTCH]
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173017/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.sourceScience Advances
dc.subjectyeast
dc.subjectnanomotion
dc.subjectoptical microscopy
dc.subjectmetabolic state
dc.subjectantifungals
dc.subjecttemperature
dc.titleSingle yeast cell nanomotions correlate with cellular activityen
dc.typearticle
dc.rights.licenseBY-NC
dc.citation.issue26
dc.citation.other6(26): -
dc.citation.rankaM21
dc.citation.volume6
dc.identifier.doi10.1126/sciadv.aba3139
dc.identifier.fulltexthttp://rimsi.imsi.bg.ac.rs/bitstream/id/272/1332.pdf
dc.identifier.pmid32637604
dc.identifier.scopus2-s2.0-85087475349
dc.identifier.wos000543504100018
dc.type.versionpublishedVersion


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