Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction
Апстракт
An analysis of the reaction of dihydroxyacetone with hydrogen peroxide was performed using HPLC with electrochemical and spectrophotometric detection and EPR spectroscopy of the reactants and products. Glycolate production in such a reaction has been documented, and the glycolate yield analyzed at different pH values. The participation of hydroxyl free radical is shown with DEPMPO spin trap. Two types of mechanisms are proposed, one at higher pH values and pronounced participation of free radicals (enhanced by the presence of metal ions and Fenton reaction) and the other at lower pH values, with decreased free radical production and lower glycolate yield.
Кључне речи:
sugar autoxidation / ketomosaccharides / hydroxyl radical / hydrogen peroxide / glycolate / Fenton reaction / electron spin resonanceИзвор:
Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus, 2005, 1048, 461-465Издавач:
- New York Acad Sciences, New York
DOI: 10.1196/annals.1342.067
ISSN: 0077-8923
PubMed: 16154978
WoS: 000233712300062
Scopus: 2-s2.0-25144438518
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Maksimović, Vuk AU - Mojović, Miloš AU - Neumann, G AU - Vučinić, Željko PY - 2005 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/130 AB - An analysis of the reaction of dihydroxyacetone with hydrogen peroxide was performed using HPLC with electrochemical and spectrophotometric detection and EPR spectroscopy of the reactants and products. Glycolate production in such a reaction has been documented, and the glycolate yield analyzed at different pH values. The participation of hydroxyl free radical is shown with DEPMPO spin trap. Two types of mechanisms are proposed, one at higher pH values and pronounced participation of free radicals (enhanced by the presence of metal ions and Fenton reaction) and the other at lower pH values, with decreased free radical production and lower glycolate yield. PB - New York Acad Sciences, New York T2 - Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus T1 - Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction EP - 465 SP - 461 VL - 1048 DO - 10.1196/annals.1342.067 ER -
@article{ author = "Maksimović, Vuk and Mojović, Miloš and Neumann, G and Vučinić, Željko", year = "2005", abstract = "An analysis of the reaction of dihydroxyacetone with hydrogen peroxide was performed using HPLC with electrochemical and spectrophotometric detection and EPR spectroscopy of the reactants and products. Glycolate production in such a reaction has been documented, and the glycolate yield analyzed at different pH values. The participation of hydroxyl free radical is shown with DEPMPO spin trap. Two types of mechanisms are proposed, one at higher pH values and pronounced participation of free radicals (enhanced by the presence of metal ions and Fenton reaction) and the other at lower pH values, with decreased free radical production and lower glycolate yield.", publisher = "New York Acad Sciences, New York", journal = "Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus", title = "Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction", pages = "465-461", volume = "1048", doi = "10.1196/annals.1342.067" }
Maksimović, V., Mojović, M., Neumann, G.,& Vučinić, Ž.. (2005). Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction. in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus New York Acad Sciences, New York., 1048, 461-465. https://doi.org/10.1196/annals.1342.067
Maksimović V, Mojović M, Neumann G, Vučinić Ž. Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction. in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus. 2005;1048:461-465. doi:10.1196/annals.1342.067 .
Maksimović, Vuk, Mojović, Miloš, Neumann, G, Vučinić, Željko, "Nonenzymatic reaction of dihydroxyacetone with hydrogen peroxide enhanced via a Fenton reaction" in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus, 1048 (2005):461-465, https://doi.org/10.1196/annals.1342.067 . .