Приказ основних података о документу

dc.creatorPejin, Boris
dc.creatorGlumac, Miodrag
dc.date.accessioned2022-04-05T15:19:07Z
dc.date.available2022-04-05T15:19:07Z
dc.date.issued2019
dc.identifier.issn1478-6419
dc.identifier.urihttp://rimsi.imsi.bg.ac.rs/handle/123456789/1209
dc.description.abstractNowadays, the mangrove biome is considered to be a profound resource of natural products usually possessing cytotoxicity of a broader range. Covering the period 2007-2015, a total of 21 new naturally occurring compounds has stood out. For example, xylogranin B and swietephragmin C were found to exhibit very potent cytotoxic activity against the colon HCT-116 cells reaching IC50 values of 0.05 and 0.06 mu M, respectively. Bearing in mind the efficacy of the majority compounds in the preliminary in vitro screens, these studies should be expanded to both ex vivo and in vivo screens including the evaluation of the relevant toxicological profiles. [GRAPHICS] .en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectorganic compoundsen
dc.subjectMangrovesen
dc.subjectcanceren
dc.titleNew cytotoxic natural products from the mangrove biome: covering the period 2007-2015en
dc.typearticle
dc.rights.licenseARR
dc.citation.epage1628
dc.citation.issue11
dc.citation.other33(11): 1624-1628
dc.citation.rankM22
dc.citation.spage1624
dc.citation.volume33
dc.identifier.doi10.1080/14786419.2018.1425854
dc.identifier.pmid29334263
dc.identifier.scopus2-s2.0-85041098943
dc.identifier.wos000472185900013
dc.type.versionpublishedVersion


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