Prikaz osnovnih podataka o dokumentu

dc.creatorKaraman, Maja
dc.creatorJanjusević, Ljiljana
dc.creatorJakovljević, Dragica
dc.creatorSibul, Filip
dc.creatorPejin, Boris
dc.date.accessioned2022-04-05T15:18:30Z
dc.date.available2022-04-05T15:18:30Z
dc.date.issued2019
dc.identifier.issn1478-6419
dc.identifier.urihttp://rimsi.imsi.bg.ac.rs/handle/123456789/1200
dc.description.abstractThis study outlines antioxidant and anti-AChE activities of the polysaccharide (PSH) extract from the mushroom species Amanita strobiliformis. Both the presence of alpha and ss glucans within the aforementioned extract was recorded. PSH extract displayed a profound scavenging activity of OH radicals (IC50 value, 11.86 +/- 0.59 mu g/mL) and high potential for reduction of Fe3+ ions (174.11 +/- 8.70 mg eq. AA/g d.w.) being almost 48- and 5-fold more effective than mannitol and butylated hydroxytoluene used as a positive control, respectively. Compared with galanthamine (0.001 mu g), the same extract exhibited a moderate anti-AChE activity (10 mu g) in solid. Since purified PSH extract exhibited higher bioactivity (IC50 value 7.27 +/- 0.31 mu g/mL, 197.68 +/- 9.47 mg eq. AA/g d.w. and 0.1 mu g, respectively), it can be predominantly ascribed to the polysaccharide compounds. A. strobiliformis PSH extract may be considered as a promising resource of potent bioactive polysaccharides of natural origin successfully addressing both oxidative stress and lack of acetylcholine.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43002/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43004/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectpolar extracten
dc.subjectMushroomsen
dc.subjectbiological activityen
dc.subjectAmanitaceaeen
dc.titleAnti-hydroxyl radical activity, redox potential and anti-AChE activity of Amanita strobiliformis polysaccharide extracten
dc.typearticle
dc.rights.licenseARR
dc.citation.epage1526
dc.citation.issue10
dc.citation.other33(10): 1522-1526
dc.citation.rankM22
dc.citation.spage1522
dc.citation.volume33
dc.identifier.doi10.1080/14786419.2017.1422183
dc.identifier.pmid29295625
dc.identifier.scopus2-s2.0-85039854192
dc.identifier.wos000469243700024
dc.type.versionpublishedVersion


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Prikaz osnovnih podataka o dokumentu