Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement
Само за регистроване кориснике
2018
Аутори
Janjusević, LjiljanaPejin, Boris
Kaisarević, Sonja
Gorjanović, Stanislava
Pastor, Ferenc
Tesanović, Kristina
Karaman, Maja
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] .
Кључне речи:
Trametes versicolor / hydroxybenzoic acids / ethanol extract / cytotoxic activity / antiradical activity / antioxidant activityИзвор:
Natural Product Research, 2018, 32, 8, 963-967Издавач:
- Taylor & Francis Ltd, Abingdon
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-172053)
- Биолошки активни природни производи као потенцијални извори нових лекова и дијететских суплемената (RS-172058)
DOI: 10.1080/14786419.2017.1366484
ISSN: 1478-6419
PubMed: 28817965
WoS: 000423771400015
Scopus: 2-s2.0-85027868180
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Janjusević, Ljiljana AU - Pejin, Boris AU - Kaisarević, Sonja AU - Gorjanović, Stanislava AU - Pastor, Ferenc AU - Tesanović, Kristina AU - Karaman, Maja PY - 2018 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/1154 AB - This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] . PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement EP - 967 IS - 8 SP - 963 VL - 32 DO - 10.1080/14786419.2017.1366484 ER -
@article{ author = "Janjusević, Ljiljana and Pejin, Boris and Kaisarević, Sonja and Gorjanović, Stanislava and Pastor, Ferenc and Tesanović, Kristina and Karaman, Maja", year = "2018", abstract = "This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] .", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement", pages = "967-963", number = "8", volume = "32", doi = "10.1080/14786419.2017.1366484" }
Janjusević, L., Pejin, B., Kaisarević, S., Gorjanović, S., Pastor, F., Tesanović, K.,& Karaman, M.. (2018). Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement. in Natural Product Research Taylor & Francis Ltd, Abingdon., 32(8), 963-967. https://doi.org/10.1080/14786419.2017.1366484
Janjusević L, Pejin B, Kaisarević S, Gorjanović S, Pastor F, Tesanović K, Karaman M. Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement. in Natural Product Research. 2018;32(8):963-967. doi:10.1080/14786419.2017.1366484 .
Janjusević, Ljiljana, Pejin, Boris, Kaisarević, Sonja, Gorjanović, Stanislava, Pastor, Ferenc, Tesanović, Kristina, Karaman, Maja, "Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement" in Natural Product Research, 32, no. 8 (2018):963-967, https://doi.org/10.1080/14786419.2017.1366484 . .