TY  - JOUR
AU  - Karaman, Maja
AU  - Tesanović, Kristina
AU  - Gorjanović, Stanislava
AU  - Pastor, Ferenc
AU  - Simonović, Mladen
AU  - Glumac, Miodrag
AU  - Pejin, Boris
PY  - 2021
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1510
AB  - This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 +/- 0.2%mu L-1) being approximate to 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient
EP  - 1716
IS  - 10
SP  - 1711
VL  - 35
DO  - 10.1080/14786419.2019.1628753
ER  - 

@article{
author = "Karaman, Maja and Tesanović, Kristina and Gorjanović, Stanislava and Pastor, Ferenc and Simonović, Mladen and Glumac, Miodrag and Pejin, Boris",
year = "2021",
abstract = "This study was focused on in vitro screening of the total antioxidant activity of the selected extracts of the mushroom Coprinus comatus and quinic acid, one of their antidiabetic ingredients, by an uncommon electrochemical assay. Indeed, direct current (DC) polarographic HydroxoPerhydroxo Mercury(II) Complex (HPMC) assay based on decrease of anodic limiting current originating from HPMC formation in alkaline solutions of hydrogen peroxide at potential of mercury dissolution, observed upon gradual addition of antioxidants, was applied herein for the estimation of the natural products' antioxidativity. Quinic acid was found to exhibit most promising antioxidant potential (4.0 +/- 0.2%mu L-1) being approximate to 2-fold more active than the screened C. comatus extract samples. Actually, such a finding puts some light on the antioxidativity of cyclic polyols, well understimated class of organic compounds, compared to aromatic (poly)phenolics. As a low cost, easy-to handle and accurate this polarographic assay may be thoroughly recommended for much broader use.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient",
pages = "1716-1711",
number = "10",
volume = "35",
doi = "10.1080/14786419.2019.1628753"
}

Karaman, M., Tesanović, K., Gorjanović, S., Pastor, F., Simonović, M., Glumac, M.,& Pejin, B.. (2021). Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 35(10), 1711-1716.
https://doi.org/10.1080/14786419.2019.1628753

Karaman M, Tesanović K, Gorjanović S, Pastor F, Simonović M, Glumac M, Pejin B. Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient. in Natural Product Research. 2021;35(10):1711-1716.
doi:10.1080/14786419.2019.1628753 .

Karaman, Maja, Tesanović, Kristina, Gorjanović, Stanislava, Pastor, Ferenc, Simonović, Mladen, Glumac, Miodrag, Pejin, Boris, "Polarography as a technique of choice for the evaluation of total antioxidant activity: The case study of selected Coprinus Comatus extracts and quinic acid, their antidiabetic ingredient" in Natural Product Research, 35, no. 10 (2021):1711-1716,
https://doi.org/10.1080/14786419.2019.1628753 . .

TY  - JOUR
AU  - Karaman, Maja
AU  - Tesanović, Kristina
AU  - Novaković, Aleksandra
AU  - Jakovljević, Dragica
AU  - Janjusević, Ljiljana
AU  - Sibul, Filip
AU  - Pejin, Boris
PY  - 2020
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1318
AB  - In vitroacetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroomCoprinus comatus(encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study.C. comatusF extract exhibited rather potent anti-AChE activity (73.0 +/- 1.5%) atin liquidconditions, comparable to those of the conventional drug donepezil (80.6 +/- 1.4%). Also, the same extract exhibited high anti-AChE activity (1 mu g)in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 mu g g(-1)d.w.) was found to affect the observed bioactivity (59.8 +/- 0.9%). This is the first report of profound anti-AChE activity of anyC. comatusextract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Coprinus comatusfiltrate extract, a novel neuroprotective agent of natural origin
EP  - 2350
IS  - 16
SP  - 2346
VL  - 34
DO  - 10.1080/14786419.2018.1533831
ER  - 

@article{
author = "Karaman, Maja and Tesanović, Kristina and Novaković, Aleksandra and Jakovljević, Dragica and Janjusević, Ljiljana and Sibul, Filip and Pejin, Boris",
year = "2020",
abstract = "In vitroacetylholinesterase (AChE) inhibitory activity of an autochthonous sample of the mushroomCoprinus comatus(encompassing fruiting body FB, mycelia M and filtrate F from the submerged cultivation) was the subject of this study.C. comatusF extract exhibited rather potent anti-AChE activity (73.0 +/- 1.5%) atin liquidconditions, comparable to those of the conventional drug donepezil (80.6 +/- 1.4%). Also, the same extract exhibited high anti-AChE activity (1 mu g)in solid. While its FTIR spectrum indicated the presence of phenolic compounds, quercetin (28.1 mu g g(-1)d.w.) was found to affect the observed bioactivity (59.8 +/- 0.9%). This is the first report of profound anti-AChE activity of anyC. comatusextract, a medicinal mushroom that has been successfully cultivated in P.R. China, due to the demanding needs of food industry.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Coprinus comatusfiltrate extract, a novel neuroprotective agent of natural origin",
pages = "2350-2346",
number = "16",
volume = "34",
doi = "10.1080/14786419.2018.1533831"
}

Karaman, M., Tesanović, K., Novaković, A., Jakovljević, D., Janjusević, L., Sibul, F.,& Pejin, B.. (2020). Coprinus comatusfiltrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 34(16), 2346-2350.
https://doi.org/10.1080/14786419.2018.1533831

Karaman M, Tesanović K, Novaković A, Jakovljević D, Janjusević L, Sibul F, Pejin B. Coprinus comatusfiltrate extract, a novel neuroprotective agent of natural origin. in Natural Product Research. 2020;34(16):2346-2350.
doi:10.1080/14786419.2018.1533831 .

Karaman, Maja, Tesanović, Kristina, Novaković, Aleksandra, Jakovljević, Dragica, Janjusević, Ljiljana, Sibul, Filip, Pejin, Boris, "Coprinus comatusfiltrate extract, a novel neuroprotective agent of natural origin" in Natural Product Research, 34, no. 16 (2020):2346-2350,
https://doi.org/10.1080/14786419.2018.1533831 . .

TY  - JOUR
AU  - Karaman, Maja
AU  - Atlagic, Kristina
AU  - Novaković, Aleksandra
AU  - Sibul, Filip
AU  - Zivić, Miroslav
AU  - Stevanović, Katarina
AU  - Pejin, Boris
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1198
AB  - Compared to plants, nowadays mushrooms attract more attention as functional foods, due to a number of advantages in manipulating them. This study aimed to screen the chemical composition (fatty acids and phenolics) and antioxidant potential (OH center dot, 2,2-diphenyl-1-picrylhydrazyl (DPPH center dot) and ferric reducing ability of plasma (FRAP)) of two edible mushrooms, Coprinus comatus and Coprinellus truncorum, collected from nature and submerged cultivation. Partial least square regression analysis has pointed out the importance of some fatty acids-more precisely, unsaturated fatty acids (UFAs) followed by fatty acids possessing both short (C6:0 and C8:0) and long (C23:0 and C24:0) saturated chains-and phenolic compounds (such as protocatechuic acid, daidzein, p-hydroxybenzoic acid, genistein and vanillic acid) for promising anti-OH center dot, FRAP and anti-DPPH center dot activities, respectively. However, other fatty acids (C16:0, C18:0 and C18:3n3) along with the flavonol isorhamnetin are actually suspected to negatively affect (by acting pro-oxidative) the aforementioned parameters, respectively. Taken together, design of new food supplements targeting oxidative stress might be predominantly based on the various UFAs combinations (C18:2n6, C20:1, C20:2, C20:4n6, C22:2, C22:1n9, etc.), particularly if OH center dot is suspected to play an important role.
PB  - MDPI, Basel
T2  - Antioxidants
T1  - Fatty Acids Predominantly Affect Anti-Hydroxyl Radical Activity and FRAP Value: The Case Study of Two Edible Mushrooms
IS  - 10
VL  - 8
DO  - 10.3390/antiox8100480
ER  - 

@article{
author = "Karaman, Maja and Atlagic, Kristina and Novaković, Aleksandra and Sibul, Filip and Zivić, Miroslav and Stevanović, Katarina and Pejin, Boris",
year = "2019",
abstract = "Compared to plants, nowadays mushrooms attract more attention as functional foods, due to a number of advantages in manipulating them. This study aimed to screen the chemical composition (fatty acids and phenolics) and antioxidant potential (OH center dot, 2,2-diphenyl-1-picrylhydrazyl (DPPH center dot) and ferric reducing ability of plasma (FRAP)) of two edible mushrooms, Coprinus comatus and Coprinellus truncorum, collected from nature and submerged cultivation. Partial least square regression analysis has pointed out the importance of some fatty acids-more precisely, unsaturated fatty acids (UFAs) followed by fatty acids possessing both short (C6:0 and C8:0) and long (C23:0 and C24:0) saturated chains-and phenolic compounds (such as protocatechuic acid, daidzein, p-hydroxybenzoic acid, genistein and vanillic acid) for promising anti-OH center dot, FRAP and anti-DPPH center dot activities, respectively. However, other fatty acids (C16:0, C18:0 and C18:3n3) along with the flavonol isorhamnetin are actually suspected to negatively affect (by acting pro-oxidative) the aforementioned parameters, respectively. Taken together, design of new food supplements targeting oxidative stress might be predominantly based on the various UFAs combinations (C18:2n6, C20:1, C20:2, C20:4n6, C22:2, C22:1n9, etc.), particularly if OH center dot is suspected to play an important role.",
publisher = "MDPI, Basel",
journal = "Antioxidants",
title = "Fatty Acids Predominantly Affect Anti-Hydroxyl Radical Activity and FRAP Value: The Case Study of Two Edible Mushrooms",
number = "10",
volume = "8",
doi = "10.3390/antiox8100480"
}

Karaman, M., Atlagic, K., Novaković, A., Sibul, F., Zivić, M., Stevanović, K.,& Pejin, B.. (2019). Fatty Acids Predominantly Affect Anti-Hydroxyl Radical Activity and FRAP Value: The Case Study of Two Edible Mushrooms. in Antioxidants
MDPI, Basel., 8(10).
https://doi.org/10.3390/antiox8100480

Karaman M, Atlagic K, Novaković A, Sibul F, Zivić M, Stevanović K, Pejin B. Fatty Acids Predominantly Affect Anti-Hydroxyl Radical Activity and FRAP Value: The Case Study of Two Edible Mushrooms. in Antioxidants. 2019;8(10).
doi:10.3390/antiox8100480 .

Karaman, Maja, Atlagic, Kristina, Novaković, Aleksandra, Sibul, Filip, Zivić, Miroslav, Stevanović, Katarina, Pejin, Boris, "Fatty Acids Predominantly Affect Anti-Hydroxyl Radical Activity and FRAP Value: The Case Study of Two Edible Mushrooms" in Antioxidants, 8, no. 10 (2019),
https://doi.org/10.3390/antiox8100480 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Tesanović, Kristina
AU  - Jakovljević, Dragica
AU  - Kaisarević, Sonja
AU  - Sibul, Filip
AU  - Raseta, Milena
AU  - Karaman, Maja
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1277
AB  - The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 +/- 0.07 and 0.61 +/- 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained beta-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer's disease. [GRAPHICS] .
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity
EP  - 754
IS  - 5
SP  - 750
VL  - 33
DO  - 10.1080/14786419.2017.1405417
ER  - 

@article{
author = "Pejin, Boris and Tesanović, Kristina and Jakovljević, Dragica and Kaisarević, Sonja and Sibul, Filip and Raseta, Milena and Karaman, Maja",
year = "2019",
abstract = "The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 +/- 0.07 and 0.61 +/- 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained beta-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer's disease. [GRAPHICS] .",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity",
pages = "754-750",
number = "5",
volume = "33",
doi = "10.1080/14786419.2017.1405417"
}

Pejin, B., Tesanović, K., Jakovljević, D., Kaisarević, S., Sibul, F., Raseta, M.,& Karaman, M.. (2019). The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 33(5), 750-754.
https://doi.org/10.1080/14786419.2017.1405417

Pejin B, Tesanović K, Jakovljević D, Kaisarević S, Sibul F, Raseta M, Karaman M. The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity. in Natural Product Research. 2019;33(5):750-754.
doi:10.1080/14786419.2017.1405417 .

Pejin, Boris, Tesanović, Kristina, Jakovljević, Dragica, Kaisarević, Sonja, Sibul, Filip, Raseta, Milena, Karaman, Maja, "The polysaccharide extracts from the fungi Coprinus comatus and Coprinellus truncorum do exhibit AChE inhibitory activity" in Natural Product Research, 33, no. 5 (2019):750-754,
https://doi.org/10.1080/14786419.2017.1405417 . .

TY  - JOUR
AU  - Žižić, Milan
AU  - Zakrzewska, Joanna
AU  - Tesanović, Kristina
AU  - Bosković, Eleonora
AU  - Nesović, Milica
AU  - Karaman, Maja
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1119
AB  - Vanadate is proposed to play a pivotal role in application of edible fungus Coprinus comatus for medical purposes. In this study the concentration of extracellular vanadate acceptable for the submerged cultivation of C. comatus mycelium was established. The mycelium could grow, and overcome vanadate toxic effects, up to the concentration of 3.3 mM. Moreover, in this condition, at the end of the exponential phase of growth, biomass yield was almost identical to that in the control. P-31 NMR spectroscopy showed that addition of 10 mM vanadate to the mycelium in the exponential phase of growth provoked instantaneous increase of a sugar phosphates level which could be related to changes in activities of glycolytic enzymes. Exposure to higher vanadate concentration was toxic for the cell. V-51 NMR measurements revealed that monomer of vanadate is present in the cytoplasm causing the metabolic changes. C. comatus has also capacity for vanadate reduction, as shown by EPR measurements, but vanadyl uptake is significantly less comparing to vanadate.
PB  - Elsevier Gmbh, Munich
T2  - Journal of Trace Elements in Medicine and Biology
T1  - Effects of vanadate on the mycelium of edible fungus Coprinus comatus
EP  - 326
SP  - 320
VL  - 50
DO  - 10.1016/j.jtemb.2018.07.017
ER  - 

@article{
author = "Žižić, Milan and Zakrzewska, Joanna and Tesanović, Kristina and Bosković, Eleonora and Nesović, Milica and Karaman, Maja",
year = "2018",
abstract = "Vanadate is proposed to play a pivotal role in application of edible fungus Coprinus comatus for medical purposes. In this study the concentration of extracellular vanadate acceptable for the submerged cultivation of C. comatus mycelium was established. The mycelium could grow, and overcome vanadate toxic effects, up to the concentration of 3.3 mM. Moreover, in this condition, at the end of the exponential phase of growth, biomass yield was almost identical to that in the control. P-31 NMR spectroscopy showed that addition of 10 mM vanadate to the mycelium in the exponential phase of growth provoked instantaneous increase of a sugar phosphates level which could be related to changes in activities of glycolytic enzymes. Exposure to higher vanadate concentration was toxic for the cell. V-51 NMR measurements revealed that monomer of vanadate is present in the cytoplasm causing the metabolic changes. C. comatus has also capacity for vanadate reduction, as shown by EPR measurements, but vanadyl uptake is significantly less comparing to vanadate.",
publisher = "Elsevier Gmbh, Munich",
journal = "Journal of Trace Elements in Medicine and Biology",
title = "Effects of vanadate on the mycelium of edible fungus Coprinus comatus",
pages = "326-320",
volume = "50",
doi = "10.1016/j.jtemb.2018.07.017"
}

Žižić, M., Zakrzewska, J., Tesanović, K., Bosković, E., Nesović, M.,& Karaman, M.. (2018). Effects of vanadate on the mycelium of edible fungus Coprinus comatus. in Journal of Trace Elements in Medicine and Biology
Elsevier Gmbh, Munich., 50, 320-326.
https://doi.org/10.1016/j.jtemb.2018.07.017

Žižić M, Zakrzewska J, Tesanović K, Bosković E, Nesović M, Karaman M. Effects of vanadate on the mycelium of edible fungus Coprinus comatus. in Journal of Trace Elements in Medicine and Biology. 2018;50:320-326.
doi:10.1016/j.jtemb.2018.07.017 .

Žižić, Milan, Zakrzewska, Joanna, Tesanović, Kristina, Bosković, Eleonora, Nesović, Milica, Karaman, Maja, "Effects of vanadate on the mycelium of edible fungus Coprinus comatus" in Journal of Trace Elements in Medicine and Biology, 50 (2018):320-326,
https://doi.org/10.1016/j.jtemb.2018.07.017 . .

TY  - JOUR
AU  - Janjusević, Ljiljana
AU  - Pejin, Boris
AU  - Kaisarević, Sonja
AU  - Gorjanović, Stanislava
AU  - Pastor, Ferenc
AU  - Tesanović, Kristina
AU  - Karaman, Maja
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1154
AB  - This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] .
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement
EP  - 967
IS  - 8
SP  - 963
VL  - 32
DO  - 10.1080/14786419.2017.1366484
ER  - 

@article{
author = "Janjusević, Ljiljana and Pejin, Boris and Kaisarević, Sonja and Gorjanović, Stanislava and Pastor, Ferenc and Tesanović, Kristina and Karaman, Maja",
year = "2018",
abstract = "This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O-2(center dot-) and NO center dot (29.62 and 52.48g/mL, respectively). It also showed a good AO activity in the polarographic HPMC assay (950%/mL). p-Hydroxybenzoic acid may be one of the responsible compounds for the afore-mentioned activities. The same extract also exhibited a concentration-dependent cytotoxicity against MCF-7 and HepG2 tumour cell lines reaching IC50 values of 123.51 and 134.29g/mL, respectively with no cytotoxic activity against normal MRC-5 cells. Gentisic, syringic and protocatechuic acids may be among the bioactive principles for the observed cytotoxicity. Taken all together, T. versicolor ethanol extract can be considered as a promising candidate for development of health promoting food supplement. [GRAPHICS] .",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement",
pages = "967-963",
number = "8",
volume = "32",
doi = "10.1080/14786419.2017.1366484"
}

Janjusević, L., Pejin, B., Kaisarević, S., Gorjanović, S., Pastor, F., Tesanović, K.,& Karaman, M.. (2018). Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 32(8), 963-967.
https://doi.org/10.1080/14786419.2017.1366484

Janjusević L, Pejin B, Kaisarević S, Gorjanović S, Pastor F, Tesanović K, Karaman M. Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement. in Natural Product Research. 2018;32(8):963-967.
doi:10.1080/14786419.2017.1366484 .

Janjusević, Ljiljana, Pejin, Boris, Kaisarević, Sonja, Gorjanović, Stanislava, Pastor, Ferenc, Tesanović, Kristina, Karaman, Maja, "Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement" in Natural Product Research, 32, no. 8 (2018):963-967,
https://doi.org/10.1080/14786419.2017.1366484 . .

TY  - JOUR
AU  - Tesanović, Kristina
AU  - Pejin, Boris
AU  - Sibul, Filip
AU  - Matavulj, Milan
AU  - Raseta, Milena
AU  - Janjusević, Ljiljana
AU  - Karaman, Maja
PY  - 2017
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1095
AB  - Bioactive properties of fungi considerably differ between the fruiting body (FB) and the submerged culture as regards mycelia (M) and the fermentation broth (F). Antioxidant properties of hot-water extracts obtained from three different fungal origins: FB, M and F of two autochthonous fungal species (Northern Serbia), Coprinus comatus and Coprinellus truncorum were investigated. Free radical scavenging capacity (RSC) was evaluated in vitro by the DPPH assay and reducing power ability (FRAP assay). Considering possible bioactive properties of different compounds present in fungal extracts, the content of total proteins (TP), phenols (TC) and flavonoids (TF) were investigated colorimetrically. The chemical characterisation of the examined extracts was evaluated using the HPLC-MS/MS method. C. comatus showed the strongest RSC activity; more precisely, fermentation broth extract (FCc) on DPPH radicals (IC50 = 5.06 mu g mL(-1)) and fruiting body extract (FBCc) for the FRAP assay (42.86 mg ascorbic acid equivalents (AAE)/g). Submerged M extract of both species showed the highest TC (MCc 81.95 mg gallic acid eq (GAE)/g d.w.; MCt 81.64 mg GAE/g d.w.), while FB extracts contained the highest content of TP. Comparing LC-MS phenolic profiles between species-interspecifically and among different fungal origins-intraspecifically (fruiting bodies and submerged cultures), high variations were noticed. In submerged M or F extracts of C. comatus, vanillic, gallic, gentisic and cinnamic acids were detected, as opposed to FB. Considering that diverse phenolic profiles of detected antioxidant compounds were obtained by submerged cultivation, this type of cultivation is promising for the production of antioxidant substances.
PB  - Springer India, New Delhi
T2  - Journal of Food Science and Technology-Mysore
T1  - A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum
EP  - 438
IS  - 2
SP  - 430
VL  - 54
DO  - 10.1007/s13197-016-2479-2
ER  - 

@article{
author = "Tesanović, Kristina and Pejin, Boris and Sibul, Filip and Matavulj, Milan and Raseta, Milena and Janjusević, Ljiljana and Karaman, Maja",
year = "2017",
abstract = "Bioactive properties of fungi considerably differ between the fruiting body (FB) and the submerged culture as regards mycelia (M) and the fermentation broth (F). Antioxidant properties of hot-water extracts obtained from three different fungal origins: FB, M and F of two autochthonous fungal species (Northern Serbia), Coprinus comatus and Coprinellus truncorum were investigated. Free radical scavenging capacity (RSC) was evaluated in vitro by the DPPH assay and reducing power ability (FRAP assay). Considering possible bioactive properties of different compounds present in fungal extracts, the content of total proteins (TP), phenols (TC) and flavonoids (TF) were investigated colorimetrically. The chemical characterisation of the examined extracts was evaluated using the HPLC-MS/MS method. C. comatus showed the strongest RSC activity; more precisely, fermentation broth extract (FCc) on DPPH radicals (IC50 = 5.06 mu g mL(-1)) and fruiting body extract (FBCc) for the FRAP assay (42.86 mg ascorbic acid equivalents (AAE)/g). Submerged M extract of both species showed the highest TC (MCc 81.95 mg gallic acid eq (GAE)/g d.w.; MCt 81.64 mg GAE/g d.w.), while FB extracts contained the highest content of TP. Comparing LC-MS phenolic profiles between species-interspecifically and among different fungal origins-intraspecifically (fruiting bodies and submerged cultures), high variations were noticed. In submerged M or F extracts of C. comatus, vanillic, gallic, gentisic and cinnamic acids were detected, as opposed to FB. Considering that diverse phenolic profiles of detected antioxidant compounds were obtained by submerged cultivation, this type of cultivation is promising for the production of antioxidant substances.",
publisher = "Springer India, New Delhi",
journal = "Journal of Food Science and Technology-Mysore",
title = "A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum",
pages = "438-430",
number = "2",
volume = "54",
doi = "10.1007/s13197-016-2479-2"
}

Tesanović, K., Pejin, B., Sibul, F., Matavulj, M., Raseta, M., Janjusević, L.,& Karaman, M.. (2017). A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum. in Journal of Food Science and Technology-Mysore
Springer India, New Delhi., 54(2), 430-438.
https://doi.org/10.1007/s13197-016-2479-2

Tesanović K, Pejin B, Sibul F, Matavulj M, Raseta M, Janjusević L, Karaman M. A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum. in Journal of Food Science and Technology-Mysore. 2017;54(2):430-438.
doi:10.1007/s13197-016-2479-2 .

Tesanović, Kristina, Pejin, Boris, Sibul, Filip, Matavulj, Milan, Raseta, Milena, Janjusević, Ljiljana, Karaman, Maja, "A comparative overview of antioxidative properties and phenolic profiles of different fungal origins: fruiting bodies and submerged cultures of Coprinus comatus and Coprinellus truncorum" in Journal of Food Science and Technology-Mysore, 54, no. 2 (2017):430-438,
https://doi.org/10.1007/s13197-016-2479-2 . .