In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)
Nema prikaza
Autori
Pejin, BorisTalevska, Aleksandra
Ciric, Ana
Glamočlija, Jasmina
Nikolic, Milos
Talevski, Trajce
Soković, Marina
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepw...ater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity.
Ključne reči:
Porifera / Ohrid / fungi / extracts / endemic species / bacteriaIzvor:
Natural Product Research, 2014, 28, 18, 1489-1494Izdavač:
- Taylor & Francis Ltd, Abingdon
Finansiranje / projekti:
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-MESTD-Basic Research (BR or ON)-172053)
- Karakterizacija i primena metabolita gljiva i utvrđivanje potencijala novih biofungicida (RS-MESTD-Basic Research (BR or ON)-173032)
DOI: 10.1080/14786419.2014.911297
ISSN: 1478-6419
PubMed: 24804931
WoS: 000340273000012
Scopus: 2-s2.0-84905387420
Institucija/grupa
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Talevska, Aleksandra AU - Ciric, Ana AU - Glamočlija, Jasmina AU - Nikolic, Milos AU - Talevski, Trajce AU - Soković, Marina PY - 2014 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/784 AB - The antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepwater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity. PB - Taylor & Francis Ltd, Abingdon T2 - Natural Product Research T1 - In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) EP - 1494 IS - 18 SP - 1489 VL - 28 DO - 10.1080/14786419.2014.911297 ER -
@article{ author = "Pejin, Boris and Talevska, Aleksandra and Ciric, Ana and Glamočlija, Jasmina and Nikolic, Milos and Talevski, Trajce and Soković, Marina", year = "2014", abstract = "The antimicrobial activity of five crude extracts (aqueous, methanol, ethyl acetate, acetone and methylene chloride) of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937) was evaluated in vitro by using microdilution method against eight bacterial and eight fungal strains for the first time. The extracts were proven to be active in varying degrees against all the bacteria and fungi tested. O. rotunda methanol extract exhibited the highest antibacterial activity (minimum inhibitory concentration (MIC) 7.5-15.0 mu g/mL and minimum bactericidal concentration 15-30 mu g/mL), while its acetone extract exhibited the most promising antifungal activity (MIC 7.5-45.0 mu g/mL and minimum fungicidal concentration 15-60 mu g/mL). The extracts were more effective against the bacteria and fungi screened compared with the positive controls (streptomycin and ampicillin for bacteria and bifonazole and ketoconazole for fungi, respectively). According to the experimental data obtained, this deepwater sponge species may be considered as a gold mine of new antimicrobial substances with significant and broad-range activity.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Natural Product Research", title = "In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)", pages = "1494-1489", number = "18", volume = "28", doi = "10.1080/14786419.2014.911297" }
Pejin, B., Talevska, A., Ciric, A., Glamočlija, J., Nikolic, M., Talevski, T.,& Soković, M.. (2014). In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937). in Natural Product Research Taylor & Francis Ltd, Abingdon., 28(18), 1489-1494. https://doi.org/10.1080/14786419.2014.911297
Pejin B, Talevska A, Ciric A, Glamočlija J, Nikolic M, Talevski T, Soković M. In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937). in Natural Product Research. 2014;28(18):1489-1494. doi:10.1080/14786419.2014.911297 .
Pejin, Boris, Talevska, Aleksandra, Ciric, Ana, Glamočlija, Jasmina, Nikolic, Milos, Talevski, Trajce, Soković, Marina, "In vitro evaluation of antimicrobial activity of the freshwater sponge Ochridaspongia rotunda (Arndt, 1937)" in Natural Product Research, 28, no. 18 (2014):1489-1494, https://doi.org/10.1080/14786419.2014.911297 . .