Avarol effectively inhibits bacillus cereus growth
Abstract
This work extends in vitro screening of antibacterial activity of avarol on four selected pathogenic bacteria associated with psoriasis (Bacillus cereus, Clostridium sporogenes, Enterococcus faecalis and Staphylococcus aureus). Avarol exhibited a moderate activity with minimum inhibitory and minimum bactericidal concentrations ranged from 0.78-1.56 and 3.12-18.75 μg/mL, respectively. It proved to be more effective against B. cereus in comparison to the both positive controls applied, gentamycin and ampicillin. According to the experimental data, this marine natural product may inspire development of new antibiotics with an enhanced therapeutic index, at first place those targeting B. cereus.
Keywords:
Psoriasis / Porifera / Marine natural product / Dysidea avara / Antibacterial activitySource:
Asian Journal of Chemistry, 2014, 26, 23, 8255-8256Publisher:
- Chemical Publishing Co.
Collections
Institution/Community
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Kartali, T. AU - Stanimirović, Bojana AU - Karaman, M. PY - 2014 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/745 AB - This work extends in vitro screening of antibacterial activity of avarol on four selected pathogenic bacteria associated with psoriasis (Bacillus cereus, Clostridium sporogenes, Enterococcus faecalis and Staphylococcus aureus). Avarol exhibited a moderate activity with minimum inhibitory and minimum bactericidal concentrations ranged from 0.78-1.56 and 3.12-18.75 μg/mL, respectively. It proved to be more effective against B. cereus in comparison to the both positive controls applied, gentamycin and ampicillin. According to the experimental data, this marine natural product may inspire development of new antibiotics with an enhanced therapeutic index, at first place those targeting B. cereus. PB - Chemical Publishing Co. T2 - Asian Journal of Chemistry T1 - Avarol effectively inhibits bacillus cereus growth EP - 8256 IS - 23 SP - 8255 VL - 26 DO - 10.14233/ajchem.2014.17640 ER -
@article{ author = "Pejin, Boris and Kartali, T. and Stanimirović, Bojana and Karaman, M.", year = "2014", abstract = "This work extends in vitro screening of antibacterial activity of avarol on four selected pathogenic bacteria associated with psoriasis (Bacillus cereus, Clostridium sporogenes, Enterococcus faecalis and Staphylococcus aureus). Avarol exhibited a moderate activity with minimum inhibitory and minimum bactericidal concentrations ranged from 0.78-1.56 and 3.12-18.75 μg/mL, respectively. It proved to be more effective against B. cereus in comparison to the both positive controls applied, gentamycin and ampicillin. According to the experimental data, this marine natural product may inspire development of new antibiotics with an enhanced therapeutic index, at first place those targeting B. cereus.", publisher = "Chemical Publishing Co.", journal = "Asian Journal of Chemistry", title = "Avarol effectively inhibits bacillus cereus growth", pages = "8256-8255", number = "23", volume = "26", doi = "10.14233/ajchem.2014.17640" }
Pejin, B., Kartali, T., Stanimirović, B.,& Karaman, M.. (2014). Avarol effectively inhibits bacillus cereus growth. in Asian Journal of Chemistry Chemical Publishing Co.., 26(23), 8255-8256. https://doi.org/10.14233/ajchem.2014.17640
Pejin B, Kartali T, Stanimirović B, Karaman M. Avarol effectively inhibits bacillus cereus growth. in Asian Journal of Chemistry. 2014;26(23):8255-8256. doi:10.14233/ajchem.2014.17640 .
Pejin, Boris, Kartali, T., Stanimirović, Bojana, Karaman, M., "Avarol effectively inhibits bacillus cereus growth" in Asian Journal of Chemistry, 26, no. 23 (2014):8255-8256, https://doi.org/10.14233/ajchem.2014.17640 . .