In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata
2013
Аутори
Pejin, BorisStanimirović, Bojana
Đorđević, Neda O
Hegediš, Aleksandar
Karaman, Ivo M
Horvatović, Mladen
Radotić, Ksenija
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The objective of the present study was in vitro evaluation of radioprotective activity of the freshwater bryozoan Hyalinella punctata on cultured human peripheral blood lymphocytes after irradiation with 2 gy of Co-60 gamma-rays. Since its water extract at concentration 0.001 mg/mL reduced the incidence of radiation-induced micronuclei for almost 30 %, it could be considered as a promising source of new natural products with the aforementined activity. Both the content of sulphur (1.17%) determined by gravimetric method and infrared absorption frequences (76 % similarity with those of bacitracin) of the investigated extract indicate the presence of organic sulphur compound(s) such as cyclic peptides and polypeptides which might be responsible for the observed radioprotection
Кључне речи:
Plumatellidae / Lymphocytes / Ionising radiation / ExtractИзвор:
Asian Journal of Chemistry, 2013, 25, 8, 4713-4714Издавач:
- Asian Journal Of Chemistry, Sahibabad
Финансирање / пројекти:
- Радиосензитивност хуманог генома (RS-173046)
- Синтеза, процесирање и карактеризација наноструктурних материјала за примену у области енергије, механичког инжењерства, заштите животне стредине и биомедицине (RS-45012)
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-172053)
- Интеракције мембрана са унутарћелијским и апопластичним простором: изучавања биоенергетике и сингализације користећи биофизичке и биохемијске методе (RS-173040)
- Истраживање климатских промена и њиховог утицаја на животну средину - праћење утицаја, адаптација и ублажавање (RS-43007)
DOI: 10.14233/ajchem.2013.14917
ISSN: 0970-7077
WoS: 000317246400144
Scopus: 2-s2.0-84877251766
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Pejin, Boris AU - Stanimirović, Bojana AU - Đorđević, Neda O AU - Hegediš, Aleksandar AU - Karaman, Ivo M AU - Horvatović, Mladen AU - Radotić, Ksenija PY - 2013 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/651 AB - The objective of the present study was in vitro evaluation of radioprotective activity of the freshwater bryozoan Hyalinella punctata on cultured human peripheral blood lymphocytes after irradiation with 2 gy of Co-60 gamma-rays. Since its water extract at concentration 0.001 mg/mL reduced the incidence of radiation-induced micronuclei for almost 30 %, it could be considered as a promising source of new natural products with the aforementined activity. Both the content of sulphur (1.17%) determined by gravimetric method and infrared absorption frequences (76 % similarity with those of bacitracin) of the investigated extract indicate the presence of organic sulphur compound(s) such as cyclic peptides and polypeptides which might be responsible for the observed radioprotection PB - Asian Journal Of Chemistry, Sahibabad T2 - Asian Journal of Chemistry T1 - In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata EP - 4714 IS - 8 SP - 4713 VL - 25 DO - 10.14233/ajchem.2013.14917 ER -
@article{ author = "Pejin, Boris and Stanimirović, Bojana and Đorđević, Neda O and Hegediš, Aleksandar and Karaman, Ivo M and Horvatović, Mladen and Radotić, Ksenija", year = "2013", abstract = "The objective of the present study was in vitro evaluation of radioprotective activity of the freshwater bryozoan Hyalinella punctata on cultured human peripheral blood lymphocytes after irradiation with 2 gy of Co-60 gamma-rays. Since its water extract at concentration 0.001 mg/mL reduced the incidence of radiation-induced micronuclei for almost 30 %, it could be considered as a promising source of new natural products with the aforementined activity. Both the content of sulphur (1.17%) determined by gravimetric method and infrared absorption frequences (76 % similarity with those of bacitracin) of the investigated extract indicate the presence of organic sulphur compound(s) such as cyclic peptides and polypeptides which might be responsible for the observed radioprotection", publisher = "Asian Journal Of Chemistry, Sahibabad", journal = "Asian Journal of Chemistry", title = "In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata", pages = "4714-4713", number = "8", volume = "25", doi = "10.14233/ajchem.2013.14917" }
Pejin, B., Stanimirović, B., Đorđević, N. O., Hegediš, A., Karaman, I. M., Horvatović, M.,& Radotić, K.. (2013). In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata. in Asian Journal of Chemistry Asian Journal Of Chemistry, Sahibabad., 25(8), 4713-4714. https://doi.org/10.14233/ajchem.2013.14917
Pejin B, Stanimirović B, Đorđević NO, Hegediš A, Karaman IM, Horvatović M, Radotić K. In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata. in Asian Journal of Chemistry. 2013;25(8):4713-4714. doi:10.14233/ajchem.2013.14917 .
Pejin, Boris, Stanimirović, Bojana, Đorđević, Neda O, Hegediš, Aleksandar, Karaman, Ivo M, Horvatović, Mladen, Radotić, Ksenija, "In vitro Radioprotective Activity of the Bryozoan Hyalinella punctata" in Asian Journal of Chemistry, 25, no. 8 (2013):4713-4714, https://doi.org/10.14233/ajchem.2013.14917 . .