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Dynamic of tributyltin influence on DNA damage in haemocytes and cardiac activity of the Mediterranean mussel Mytilus galloprovincialis
(Institute of Experimental Medicine (Prague, Czech Republic) and the University of Kentucky (USA), 2016)
Adverse effects of antifouling paints containing organotin compound tributylin (TBT) marked this agent as one of the most toxic substances released into the sea; therefore, its usage is banned. Considering the lack of TBT ...
Application of comet assay in aquatic organisms – summary and lessons learned in past 10 years of field research
(EUROPEAN ENVIRONMENTAL MUTAGENESIS & GENOMICS SOCIETY, 2022)
Within the past decade, our research group placed great effort in exploration of the impact of treated/untreated wastewaters on aquatic ecosystems as less than 13 % of collected municipal wastewaters are processed before ...
Significance of genotoxicity and toxicity evaluation of freshwater bodies
(Institute of Marine Biology, University of Montenegro, 2019)
Fish communities are excellent indicators of biological and ecological integrity due to
their continuous exposure to water conditions. Freshwater biodiversity constitute a valu able natural resource but extensive pollution ...
Identification of hotspots of genotoxicological and faecal pollution along the Danube and Sava rivers – the whole river surveys
(University of Agriculture in Krakow, 2018)
The level of genotoxic pollution was assessed along the Danube River and its most significant tributary Sava River by measuring the level of DNA damage in aquatic organisms collected from the selected sites. The Danube ...
Evaluation of genotoxic potential of the middle section of the Danube River and its major tributaries
(EUROPEAN ENVIRONMENTAL MUTAGENESIS & GENOMICS SOCIETY, 2022)
The middle section of the Danube River basin in the previous three Joint Danube Surveys (JDS) was found to be under intensive pollution, mainly affected by wastewaters. As a consequence of the lack of wastewater treatment ...
Comet assay and cytogenetic findings in differential diagnosis of fanconi anemia
(Društvo genetičara Srbije, Beograd, 2019)
Fanconi anemia (FA) is a complex genetic disease with a variety of congenital and hematological symptoms, including the predisposition for cancer development. The main hallmark of FA cells, an increased chromosomal fragility, ...
Evaluation of genotoxic potential oftert-butylquinone and its derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2020)
Tert-butylquinone (TBQ) and its alkylamino and aralkylamino derivatives are of high interest as a potential antitumor agent. Therefore, it was necessary to investigate if the compounds exert undesirable activities such as ...
Raspberry seeds extract selectively inhibits the growth of human lung cancer cells in vitro
(Taylor & Francis Ltd, Abingdon, 2021)
This study was focused on in vitro cytotoxicity screening of the raspberry seeds methanol extract towards a number of cancer cell lines of human origin. The tested extract at the preferred concentrations (IC50 lt 30 mu ...
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
(Taylor & Francis Ltd, Abingdon, 2019)
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3 '-methoxyavarone, 4 '-(methylamino)avarone and 3 '-(methylamino)avarone was evaluated and compared to cytostatics ...
In vitro evaluation of cytotoxic and mutagenic activity of avarol
(Taylor & Francis Ltd, Abingdon, 2016)
The cytotoxicity of avarol, a main secondary metabolite of the Mediterranean sponge Dysidea avara, was in vitro screened by MTT assay against four human tumour cell lines. The colon HT-29 tumour cells practically showed ...