Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird
Аутори
Buehler, Deborah M.Bhola, Nina
Stanković, Daliborka
Goymann, Wolfgang
Schwabl, Ingrid
Tieleman, B. Irene
Piersma, Theunis
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Ecological immunologists are interested in how immune function changes during different seasons and under different environmental conditions. However, an obstacle to answering such questions is discerning the effects of biological factors of interest and investigation artifacts such as handling stress. Here we examined handling stress and its effects on constitutive (noninduced) immune function via two protocols on captive red knots (Calidris canutus). We investigated how constitutive immunity responds to handling stress, how quickly these changes take place, and the practical implications for researchers interested in sampling baseline immune levels. We found that Staphylococcus aureus and Candida albicans killing increased with handling stress while total leukocyte and lymphocyte concentrations decreased. However, although corticosterone increased significantly and rapidly in response to handling stress, none of the 10 measures of constitutive immunity that we tested differed signifi...cantly from baseline withinn20 or 30 min of capture. Thus, researchers interested in baseline immune function should sample animals as soon as possible after capture, but studies in species not easily sampled in less than 3 min (such as red knots) could still yield useful results.
Кључне речи:
Constitutive immune/corticosterone/stress/baseline/ShorebirdsИзвор:
Physiological and Biochemical Zoology, 2008, 81, 5, 673-681Издавач:
- The University of Chicago
Финансирање / пројекти:
- Natural Sciences and Engineering Research Council of Canada (NSERC) PGSB-267701-2003
- University of Groningen Ubbo Emmius Scholarship
- Schure-Beijerinck-Popping Fonds
- University of Groningen
- Royal Netherlands Institute for Sea Research
- Netherlands Organization for Scientific Research
Институција/група
Institut za multidisciplinarna istraživanjaTY - JOUR AU - Buehler, Deborah M. AU - Bhola, Nina AU - Stanković, Daliborka AU - Goymann, Wolfgang AU - Schwabl, Ingrid AU - Tieleman, B. Irene AU - Piersma, Theunis PY - 2008 UR - http://rimsi.imsi.bg.ac.rs/handle/123456789/2607 AB - Ecological immunologists are interested in how immune function changes during different seasons and under different environmental conditions. However, an obstacle to answering such questions is discerning the effects of biological factors of interest and investigation artifacts such as handling stress. Here we examined handling stress and its effects on constitutive (noninduced) immune function via two protocols on captive red knots (Calidris canutus). We investigated how constitutive immunity responds to handling stress, how quickly these changes take place, and the practical implications for researchers interested in sampling baseline immune levels. We found that Staphylococcus aureus and Candida albicans killing increased with handling stress while total leukocyte and lymphocyte concentrations decreased. However, although corticosterone increased significantly and rapidly in response to handling stress, none of the 10 measures of constitutive immunity that we tested differed significantly from baseline withinn20 or 30 min of capture. Thus, researchers interested in baseline immune function should sample animals as soon as possible after capture, but studies in species not easily sampled in less than 3 min (such as red knots) could still yield useful results. PB - The University of Chicago T2 - Physiological and Biochemical Zoology T1 - Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird EP - 681 IS - 5 SP - 673 VL - 81 DO - 10.1086/588591 ER -
@article{ author = "Buehler, Deborah M. and Bhola, Nina and Stanković, Daliborka and Goymann, Wolfgang and Schwabl, Ingrid and Tieleman, B. Irene and Piersma, Theunis", year = "2008", abstract = "Ecological immunologists are interested in how immune function changes during different seasons and under different environmental conditions. However, an obstacle to answering such questions is discerning the effects of biological factors of interest and investigation artifacts such as handling stress. Here we examined handling stress and its effects on constitutive (noninduced) immune function via two protocols on captive red knots (Calidris canutus). We investigated how constitutive immunity responds to handling stress, how quickly these changes take place, and the practical implications for researchers interested in sampling baseline immune levels. We found that Staphylococcus aureus and Candida albicans killing increased with handling stress while total leukocyte and lymphocyte concentrations decreased. However, although corticosterone increased significantly and rapidly in response to handling stress, none of the 10 measures of constitutive immunity that we tested differed significantly from baseline withinn20 or 30 min of capture. Thus, researchers interested in baseline immune function should sample animals as soon as possible after capture, but studies in species not easily sampled in less than 3 min (such as red knots) could still yield useful results.", publisher = "The University of Chicago", journal = "Physiological and Biochemical Zoology", title = "Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird", pages = "681-673", number = "5", volume = "81", doi = "10.1086/588591" }
Buehler, D. M., Bhola, N., Stanković, D., Goymann, W., Schwabl, I., Tieleman, B. I.,& Piersma, T.. (2008). Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird. in Physiological and Biochemical Zoology The University of Chicago., 81(5), 673-681. https://doi.org/10.1086/588591
Buehler DM, Bhola N, Stanković D, Goymann W, Schwabl I, Tieleman BI, Piersma T. Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird. in Physiological and Biochemical Zoology. 2008;81(5):673-681. doi:10.1086/588591 .
Buehler, Deborah M., Bhola, Nina, Stanković, Daliborka, Goymann, Wolfgang, Schwabl, Ingrid, Tieleman, B. Irene, Piersma, Theunis, "Constitutive Immune Function Responds More Slowly to Handling Stress than Corticosterone in a Shorebird" in Physiological and Biochemical Zoology, 81, no. 5 (2008):673-681, https://doi.org/10.1086/588591 . .