TY  - JOUR
AU  - Todorović, Tamara
AU  - Vukašinović, Jelena
AU  - Portalone, Gustavo
AU  - suleiman, sherif
AU  - Gligorijević, Nevenka
AU  - Bjelogrlic, Snezana K.
AU  - Jovanovic, Katarina
AU  - Radulović, Sinisa S
AU  - Andjelkovic, Katarina
AU  - Cassar, Analisse
AU  - Filipović, Nenad
AU  - Schembri-WIsmayer, Pierre
PY  - 2017
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2027
AB  - Cobaltcomplexeswithsemi-andthiosemicarbazonesof8-quinolinecarboxaldehydehavebeensynthesizedandcharacterizedbyX-raydiffractionanalysis.Thesenovelcomplexesandapreviouslysynthesized cobaltcomplexwithaselenium-basedselenosemicarbazoneligandshowedmyeloiddifferentiationactivity onalltransretinoicacidresistantHL-60acutemyeloidleukaemiacells.Theyalsoshowedvaryinglevelsof cytotoxicityonfivehumantumorcelllines:cervixcarcinomacells(HeLa),lungadenocarcinomacells (A549),colorectaladenocarcinomacells(LS-174),breastcarcinomacells(MDA-MB-361),andchronicmyeloidleukaemia(K562)aswellasonenormalhumancellline:fetallungfibroblastcells(MRC-5).Leukaemia differentiationwasmoststronglyinducedbyametal-freeoxygenligandandtheseleniumligand,whilst thelatterandthecobaltIJII)complexwithanoxygenligandshowedthestrongestdose-dependentcytotoxic activity.Infouroutoffiveinvestigatedtumorcelllines,itwasofthesameorderofmagnitudeascisplatin. Thesebestcompounds,however,hadlowertoxicityonnon-transformedMRC-5cellsthancisplatin.
PB  - RSC Publishing
T2  - MedChemComm
T1  - (Chalcogen)semicarbazones and their cobalt complexes differentiate HL-60 myeloid leukaemia cells and are cytotoxic towards tumor cell lines
EP  - 111
IS  - 1
SP  - 103
VL  - 8
DO  - https://doi.org/10.1039/c6md00501b
ER  - 

@article{
author = "Todorović, Tamara and Vukašinović, Jelena and Portalone, Gustavo and suleiman, sherif and Gligorijević, Nevenka and Bjelogrlic, Snezana K. and Jovanovic, Katarina and Radulović, Sinisa S and Andjelkovic, Katarina and Cassar, Analisse and Filipović, Nenad and Schembri-WIsmayer, Pierre",
year = "2017",
abstract = "Cobaltcomplexeswithsemi-andthiosemicarbazonesof8-quinolinecarboxaldehydehavebeensynthesizedandcharacterizedbyX-raydiffractionanalysis.Thesenovelcomplexesandapreviouslysynthesized cobaltcomplexwithaselenium-basedselenosemicarbazoneligandshowedmyeloiddifferentiationactivity onalltransretinoicacidresistantHL-60acutemyeloidleukaemiacells.Theyalsoshowedvaryinglevelsof cytotoxicityonfivehumantumorcelllines:cervixcarcinomacells(HeLa),lungadenocarcinomacells (A549),colorectaladenocarcinomacells(LS-174),breastcarcinomacells(MDA-MB-361),andchronicmyeloidleukaemia(K562)aswellasonenormalhumancellline:fetallungfibroblastcells(MRC-5).Leukaemia differentiationwasmoststronglyinducedbyametal-freeoxygenligandandtheseleniumligand,whilst thelatterandthecobaltIJII)complexwithanoxygenligandshowedthestrongestdose-dependentcytotoxic activity.Infouroutoffiveinvestigatedtumorcelllines,itwasofthesameorderofmagnitudeascisplatin. Thesebestcompounds,however,hadlowertoxicityonnon-transformedMRC-5cellsthancisplatin.",
publisher = "RSC Publishing",
journal = "MedChemComm",
title = "(Chalcogen)semicarbazones and their cobalt complexes differentiate HL-60 myeloid leukaemia cells and are cytotoxic towards tumor cell lines",
pages = "111-103",
number = "1",
volume = "8",
doi = "https://doi.org/10.1039/c6md00501b"
}

Todorović, T., Vukašinović, J., Portalone, G., suleiman, s., Gligorijević, N., Bjelogrlic, S. K., Jovanovic, K., Radulović, S. S., Andjelkovic, K., Cassar, A., Filipović, N.,& Schembri-WIsmayer, P.. (2017). (Chalcogen)semicarbazones and their cobalt complexes differentiate HL-60 myeloid leukaemia cells and are cytotoxic towards tumor cell lines. in MedChemComm
RSC Publishing., 8(1), 103-111.
https://doi.org/https://doi.org/10.1039/c6md00501b

Todorović T, Vukašinović J, Portalone G, suleiman S, Gligorijević N, Bjelogrlic SK, Jovanovic K, Radulović SS, Andjelkovic K, Cassar A, Filipović N, Schembri-WIsmayer P. (Chalcogen)semicarbazones and their cobalt complexes differentiate HL-60 myeloid leukaemia cells and are cytotoxic towards tumor cell lines. in MedChemComm. 2017;8(1):103-111.
doi:https://doi.org/10.1039/c6md00501b .

Todorović, Tamara, Vukašinović, Jelena, Portalone, Gustavo, suleiman, sherif, Gligorijević, Nevenka, Bjelogrlic, Snezana K., Jovanovic, Katarina, Radulović, Sinisa S, Andjelkovic, Katarina, Cassar, Analisse, Filipović, Nenad, Schembri-WIsmayer, Pierre, "(Chalcogen)semicarbazones and their cobalt complexes differentiate HL-60 myeloid leukaemia cells and are cytotoxic towards tumor cell lines" in MedChemComm, 8, no. 1 (2017):103-111,
https://doi.org/https://doi.org/10.1039/c6md00501b . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Jovanović, Katarina K
AU  - Savić, Aleksandar G
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/851
AB  - This review covers the 2003-2012 literature data published for natural products originating from marine red algae. The focus is on new antitumour substances, together with details related to the organism sourced. It emphasises 14 promising compounds (isolated from 13 species) whose chemical structures are briefly discussed.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Mini-Reviews in Medicinal Chemistry
T1  - New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012
EP  - 730
IS  - 9
SP  - 720
VL  - 15
DO  - 10.2174/1389557515666150511152251
ER  - 

@article{
author = "Pejin, Boris and Jovanović, Katarina K and Savić, Aleksandar G",
year = "2015",
abstract = "This review covers the 2003-2012 literature data published for natural products originating from marine red algae. The focus is on new antitumour substances, together with details related to the organism sourced. It emphasises 14 promising compounds (isolated from 13 species) whose chemical structures are briefly discussed.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Mini-Reviews in Medicinal Chemistry",
title = "New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012",
pages = "730-720",
number = "9",
volume = "15",
doi = "10.2174/1389557515666150511152251"
}

Pejin, B., Jovanović, K. K.,& Savić, A. G.. (2015). New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012. in Mini-Reviews in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 15(9), 720-730.
https://doi.org/10.2174/1389557515666150511152251

Pejin B, Jovanović KK, Savić AG. New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012. in Mini-Reviews in Medicinal Chemistry. 2015;15(9):720-730.
doi:10.2174/1389557515666150511152251 .

Pejin, Boris, Jovanović, Katarina K, Savić, Aleksandar G, "New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012" in Mini-Reviews in Medicinal Chemistry, 15, no. 9 (2015):720-730,
https://doi.org/10.2174/1389557515666150511152251 . .

TY  - JOUR
AU  - Jovanović, Katarina K
AU  - Savić, Aleksandar G
AU  - Janković, Radmila N
AU  - Radulović, Sinisa S
AU  - Spasić, Slađana
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/702
AB  - The key method for therapies of various cancer types could be the molecular-targeted therapy, based on individual gene profile for each patient. One of the main procedures used for genetic testing is the real-time polymerase chain reaction (real-time PCR). Physical principle behind real-time PCR procedure is the fluorescence. Fluorescence labeled probes (primers) is attached to quenchers. Upon reaction of polymerization, quenchers are removed, and the fluorescence emission intensity increases in time. Emission spectra shape and its maximum position can differ if the fluorophore was present in different microenvironment. That property is widely exploited in fluorescence spectroscopy and chromatography. This paper, for the first time, describes utilization of full spectroscopic potential of multichannel excitation/emission filter sets in real-time PCR device. Instead of monitoring fluorescence intensity in time for a single fluorescence emission channel, the ratio values of three different kinetics curves were calculated and analyzed by applying k-means clustering and dendrogram analysis. Obtained results have shown that described analytical improvement provides identification of nine different groups of mutations if the commercial QIAGEN (R) EGFR PCR Kit was used. Method can be applied to any kit, capable to simultaneously detect several different mutations.
PB  - Churchill Livingstone, Edinburgh
T2  - Medical Hypotheses
T1  - Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR
EP  - 379
IS  - 4
SP  - 376
VL  - 80
DO  - 10.1016/j.mehy.2013.01.004
ER  - 

@article{
author = "Jovanović, Katarina K and Savić, Aleksandar G and Janković, Radmila N and Radulović, Sinisa S and Spasić, Slađana and Radotić, Ksenija",
year = "2013",
abstract = "The key method for therapies of various cancer types could be the molecular-targeted therapy, based on individual gene profile for each patient. One of the main procedures used for genetic testing is the real-time polymerase chain reaction (real-time PCR). Physical principle behind real-time PCR procedure is the fluorescence. Fluorescence labeled probes (primers) is attached to quenchers. Upon reaction of polymerization, quenchers are removed, and the fluorescence emission intensity increases in time. Emission spectra shape and its maximum position can differ if the fluorophore was present in different microenvironment. That property is widely exploited in fluorescence spectroscopy and chromatography. This paper, for the first time, describes utilization of full spectroscopic potential of multichannel excitation/emission filter sets in real-time PCR device. Instead of monitoring fluorescence intensity in time for a single fluorescence emission channel, the ratio values of three different kinetics curves were calculated and analyzed by applying k-means clustering and dendrogram analysis. Obtained results have shown that described analytical improvement provides identification of nine different groups of mutations if the commercial QIAGEN (R) EGFR PCR Kit was used. Method can be applied to any kit, capable to simultaneously detect several different mutations.",
publisher = "Churchill Livingstone, Edinburgh",
journal = "Medical Hypotheses",
title = "Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR",
pages = "379-376",
number = "4",
volume = "80",
doi = "10.1016/j.mehy.2013.01.004"
}

Jovanović, K. K., Savić, A. G., Janković, R. N., Radulović, S. S., Spasić, S.,& Radotić, K.. (2013). Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR. in Medical Hypotheses
Churchill Livingstone, Edinburgh., 80(4), 376-379.
https://doi.org/10.1016/j.mehy.2013.01.004

Jovanović KK, Savić AG, Janković RN, Radulović SS, Spasić S, Radotić K. Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR. in Medical Hypotheses. 2013;80(4):376-379.
doi:10.1016/j.mehy.2013.01.004 .

Jovanović, Katarina K, Savić, Aleksandar G, Janković, Radmila N, Radulović, Sinisa S, Spasić, Slađana, Radotić, Ksenija, "Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR" in Medical Hypotheses, 80, no. 4 (2013):376-379,
https://doi.org/10.1016/j.mehy.2013.01.004 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Jovanović, Katarina K
AU  - Mojović, Miloš
AU  - Savić, Aleksandar G
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/654
AB  - This review covers the 2003-2012 literature data published for antitumor natural products from marine-derived fungi. The focus is on new and highly potent cytotoxic compounds, together with details related to the relevant fungal species. It describes 22 promising bioactives, originating mainly from symbiotic fungi. The chemical structures of all highlighted organic molecules are briefly discussed.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Topics in Medicinal Chemistry
T1  - New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012
EP  - 2766
IS  - 21
SP  - 2745
VL  - 13
DO  - 10.2174/15680266113136660197
ER  - 

@article{
author = "Pejin, Boris and Jovanović, Katarina K and Mojović, Miloš and Savić, Aleksandar G",
year = "2013",
abstract = "This review covers the 2003-2012 literature data published for antitumor natural products from marine-derived fungi. The focus is on new and highly potent cytotoxic compounds, together with details related to the relevant fungal species. It describes 22 promising bioactives, originating mainly from symbiotic fungi. The chemical structures of all highlighted organic molecules are briefly discussed.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Topics in Medicinal Chemistry",
title = "New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012",
pages = "2766-2745",
number = "21",
volume = "13",
doi = "10.2174/15680266113136660197"
}

Pejin, B., Jovanović, K. K., Mojović, M.,& Savić, A. G.. (2013). New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012. in Current Topics in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 13(21), 2745-2766.
https://doi.org/10.2174/15680266113136660197

Pejin B, Jovanović KK, Mojović M, Savić AG. New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012. in Current Topics in Medicinal Chemistry. 2013;13(21):2745-2766.
doi:10.2174/15680266113136660197 .

Pejin, Boris, Jovanović, Katarina K, Mojović, Miloš, Savić, Aleksandar G, "New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012" in Current Topics in Medicinal Chemistry, 13, no. 21 (2013):2745-2766,
https://doi.org/10.2174/15680266113136660197 . .

TY  - CONF
AU  - Savić, Aleksandar G
AU  - Jovanović, Katarina K
AU  - Janković, R.
AU  - Radotić, Ksenija
AU  - Spasić, Slađana
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/563
AB  - Point mutations in conserved gene sequences are used as the trace marker for determination of evolutionary distance among the species. Novel method is based on calculation of nucleotide occurrence probability in fixed size moving window and determination of high order central moments. Description of nucleotide occurrence probability can provide high accuracy point mutation detection, and the insight into local sequence.
C3  - 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings
T1  - Determination of gene point mutations by application of higher order central moments - Preliminary research
EP  - 866
SP  - 863
DO  - 10.1109/TELFOR.2012.6419344
ER  - 

@conference{
author = "Savić, Aleksandar G and Jovanović, Katarina K and Janković, R. and Radotić, Ksenija and Spasić, Slađana",
year = "2012",
abstract = "Point mutations in conserved gene sequences are used as the trace marker for determination of evolutionary distance among the species. Novel method is based on calculation of nucleotide occurrence probability in fixed size moving window and determination of high order central moments. Description of nucleotide occurrence probability can provide high accuracy point mutation detection, and the insight into local sequence.",
journal = "2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings",
title = "Determination of gene point mutations by application of higher order central moments - Preliminary research",
pages = "866-863",
doi = "10.1109/TELFOR.2012.6419344"
}

Savić, A. G., Jovanović, K. K., Janković, R., Radotić, K.,& Spasić, S.. (2012). Determination of gene point mutations by application of higher order central moments - Preliminary research. in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings, 863-866.
https://doi.org/10.1109/TELFOR.2012.6419344

Savić AG, Jovanović KK, Janković R, Radotić K, Spasić S. Determination of gene point mutations by application of higher order central moments - Preliminary research. in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings. 2012;:863-866.
doi:10.1109/TELFOR.2012.6419344 .

Savić, Aleksandar G, Jovanović, Katarina K, Janković, R., Radotić, Ksenija, Spasić, Slađana, "Determination of gene point mutations by application of higher order central moments - Preliminary research" in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings (2012):863-866,
https://doi.org/10.1109/TELFOR.2012.6419344 . .