TY  - JOUR
AU  - Auger, Sandrine
AU  - Henry, Celine
AU  - Pechaux, Christine
AU  - Lejal, Nathalie
AU  - Zanet, Valentina
AU  - Nikolić, Maria Vesna
AU  - Manzano, Marisa
AU  - Vidic, Jasmina
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1202
AB  - The environmental contamination of soil by metal oxide nanomaterials is a growing global concern because of their potential toxicity. We investigated the effects of Mg doped ZnO (Mg-nZnO) nanoparticles on a model soil microorganism Bacillus subtilis. Mg-nZnO exhibited only a moderate toxic effect on B. subtilis vegetative cells but was able to prevent biofilm formation and destroy already formed biofilms. Similarly, Mg-nZnO ( lt = 1 mg/mL) was moderately toxic towards Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Salmonella enterica, Saccharomyces cerevisiae and murine macrophages. Engineered Mg-nZnO produced H2O2 and O-2(center dot-) radicals in solutions of various salt and organic molecule compositions. A quantitative proteomic analysis of B. subtilis membrane proteins showed that Mg-nZnO increased the expression of proteins involved in detoxification of ROS, translation and biofilm formation. Overall, our results suggest that Mg-nZnO released into the environment may hinder the spreading, colonization and biofilm formation by B. subtilis but also induce a mechanism of bacterial adaptation.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Ecotoxicology and Environmental Safety
T1  - Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis
VL  - 182
DO  - 10.1016/j.ecoenv.2019.109421
ER  - 

@article{
author = "Auger, Sandrine and Henry, Celine and Pechaux, Christine and Lejal, Nathalie and Zanet, Valentina and Nikolić, Maria Vesna and Manzano, Marisa and Vidic, Jasmina",
year = "2019",
abstract = "The environmental contamination of soil by metal oxide nanomaterials is a growing global concern because of their potential toxicity. We investigated the effects of Mg doped ZnO (Mg-nZnO) nanoparticles on a model soil microorganism Bacillus subtilis. Mg-nZnO exhibited only a moderate toxic effect on B. subtilis vegetative cells but was able to prevent biofilm formation and destroy already formed biofilms. Similarly, Mg-nZnO ( lt = 1 mg/mL) was moderately toxic towards Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Salmonella enterica, Saccharomyces cerevisiae and murine macrophages. Engineered Mg-nZnO produced H2O2 and O-2(center dot-) radicals in solutions of various salt and organic molecule compositions. A quantitative proteomic analysis of B. subtilis membrane proteins showed that Mg-nZnO increased the expression of proteins involved in detoxification of ROS, translation and biofilm formation. Overall, our results suggest that Mg-nZnO released into the environment may hinder the spreading, colonization and biofilm formation by B. subtilis but also induce a mechanism of bacterial adaptation.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Ecotoxicology and Environmental Safety",
title = "Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis",
volume = "182",
doi = "10.1016/j.ecoenv.2019.109421"
}

Auger, S., Henry, C., Pechaux, C., Lejal, N., Zanet, V., Nikolić, M. V., Manzano, M.,& Vidic, J.. (2019). Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis. in Ecotoxicology and Environmental Safety
Academic Press Inc Elsevier Science, San Diego., 182.
https://doi.org/10.1016/j.ecoenv.2019.109421

Auger S, Henry C, Pechaux C, Lejal N, Zanet V, Nikolić MV, Manzano M, Vidic J. Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis. in Ecotoxicology and Environmental Safety. 2019;182.
doi:10.1016/j.ecoenv.2019.109421 .

Auger, Sandrine, Henry, Celine, Pechaux, Christine, Lejal, Nathalie, Zanet, Valentina, Nikolić, Maria Vesna, Manzano, Marisa, Vidic, Jasmina, "Exploring the impact of Mg-doped ZnO nanoparticles on a model soil microorganism Bacillus subtilis" in Ecotoxicology and Environmental Safety, 182 (2019),
https://doi.org/10.1016/j.ecoenv.2019.109421 . .