TY  - JOUR
AU  - Gajić, Aleksa
AU  - Matić, Tamara
AU  - Obradović, Nataša
AU  - Baščarević, Zvezdana
AU  - Veljović, Đorđe
PY  - 2023
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2979
AB  - Limited bone bank capacity and risk of infection are some of the main drawbacks of autologous and allogenic grafts, giving rise to synthetic materials for bone tissue implants. The aim of this study was to process and evaluate the mechanical properties and bioactivity of magnesium and strontium doped hydroxyapatite (HAp) scaffolds and investigate the effect of adding zirconium oxide and gelatine coating the scaffolds. Doped nanosized hydroxyapatite powder was synthesized by the hydrothermal method and the scaffolds were made by the foam replica technique and sintered at different temperatures. Yttria-stabilized zirconium oxide (YSZ), synthesized by plasma technology, was used as reinforcement of calcium phosphate scaffolds. Element analysis, phase composition, morphology of the powders and microstructure of the scaffolds were investigated, as well as the compressive strength of the coated and uncoated scaffolds and bioactivity in simulated body fluid (SBF). A microporous structure was achieved with interconnected pores and bioactivity in SBF was confirmed in all cases. The best mechanical properties were given by the coated composite HAp/YSZ scaffolds, withstanding average stresses of over 1019 kPa. These results encourage the idea of use of these scaffolds in bone regenerative therapy and bone tissue engineering.
T2  - Science of Sintering
T1  - Processing of gelatine coated composite scaffolds based on magnesium and strontium doped hydroxyapatite and yttria-stabilized zirconium oxide
DO  - 10.2298/SOS220723019G
ER  - 

@article{
author = "Gajić, Aleksa and Matić, Tamara and Obradović, Nataša and Baščarević, Zvezdana and Veljović, Đorđe",
year = "2023",
abstract = "Limited bone bank capacity and risk of infection are some of the main drawbacks of autologous and allogenic grafts, giving rise to synthetic materials for bone tissue implants. The aim of this study was to process and evaluate the mechanical properties and bioactivity of magnesium and strontium doped hydroxyapatite (HAp) scaffolds and investigate the effect of adding zirconium oxide and gelatine coating the scaffolds. Doped nanosized hydroxyapatite powder was synthesized by the hydrothermal method and the scaffolds were made by the foam replica technique and sintered at different temperatures. Yttria-stabilized zirconium oxide (YSZ), synthesized by plasma technology, was used as reinforcement of calcium phosphate scaffolds. Element analysis, phase composition, morphology of the powders and microstructure of the scaffolds were investigated, as well as the compressive strength of the coated and uncoated scaffolds and bioactivity in simulated body fluid (SBF). A microporous structure was achieved with interconnected pores and bioactivity in SBF was confirmed in all cases. The best mechanical properties were given by the coated composite HAp/YSZ scaffolds, withstanding average stresses of over 1019 kPa. These results encourage the idea of use of these scaffolds in bone regenerative therapy and bone tissue engineering.",
journal = "Science of Sintering",
title = "Processing of gelatine coated composite scaffolds based on magnesium and strontium doped hydroxyapatite and yttria-stabilized zirconium oxide",
doi = "10.2298/SOS220723019G"
}

Gajić, A., Matić, T., Obradović, N., Baščarević, Z.,& Veljović, Đ.. (2023). Processing of gelatine coated composite scaffolds based on magnesium and strontium doped hydroxyapatite and yttria-stabilized zirconium oxide. in Science of Sintering.
https://doi.org/10.2298/SOS220723019G

Gajić A, Matić T, Obradović N, Baščarević Z, Veljović Đ. Processing of gelatine coated composite scaffolds based on magnesium and strontium doped hydroxyapatite and yttria-stabilized zirconium oxide. in Science of Sintering. 2023;.
doi:10.2298/SOS220723019G .

Gajić, Aleksa, Matić, Tamara, Obradović, Nataša, Baščarević, Zvezdana, Veljović, Đorđe, "Processing of gelatine coated composite scaffolds based on magnesium and strontium doped hydroxyapatite and yttria-stabilized zirconium oxide" in Science of Sintering (2023),
https://doi.org/10.2298/SOS220723019G . .