TY  - CONF
AU  - Spasic, Snezana
AU  - Miletic, Srdjan
AU  - Minić, Simeon
AU  - Lugonja, Nikoleta
AU  - Marinković, Vesna
AU  - Spasojević, Ivan
AU  - Vrvic, Miroslav
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2940
AB  - Background and Aims Health benefits of mother’s milk depend on the level of the total antioxidant capacity (TAC). In mother’s milk, the TAC should refer to the sum of activities derived from active enzymatic antioxidant systems (e.g. superoxide dismutase, catalase, glutathione peroxidase etc.), nonenzymatic antioxidants, such as vitamins C and E, and the presence of other bioactive factors (e.g. lactoferrin, uric acid etc.). Measuring oxidation-reduction potential (ORP) using RedoxSYS Analyzer may be an alternative to classic methods of measuring TAC. We compared the results of OPR and ascorbic acid content in milk from mothers of preterm infants. Method Milk was obtained from ten mothers of preterm infants (gestational age 28-36 weeks; birth weight 900-2,470 g). Milk samples were obtained within the first 4 days after delivery (colostrum), from day 4 to two weeks (transient),  and 6 weeks and later (mature milk). Static oxidation−reduction potential (ORP) of milk from mothers of preterm infants was measured using RedoxSYS Analyzer (Luoxis Diagnostics, Englewood, CO). Ascorbic acid content was measured in milk samples and results were expressed as mg/l. Procedure suggested by the manufacturer was used (Reflect quant® ascorbic acid test for reflectometerRQflex®, Merck KGaA, Germany, 2006). Results There are similarities in the results of OPR and vitamin C concentration in colostrum, transient and mature milk from mothers of preterm infants. Conclusion Vitamin C concentration influenced the value of OPR most.
PB  - International Conferences on Nutrition & Growth
C3  - 3rd International Conference on Nutrition & Growth, March 17-19, 2016, Vienna, Austria
T1  - Oxidation-reduction potential in the milk from mothers of preterm infants
SP  - 110
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2940
ER  - 

@conference{
author = "Spasic, Snezana and Miletic, Srdjan and Minić, Simeon and Lugonja, Nikoleta and Marinković, Vesna and Spasojević, Ivan and Vrvic, Miroslav",
year = "2016",
abstract = "Background and Aims Health benefits of mother’s milk depend on the level of the total antioxidant capacity (TAC). In mother’s milk, the TAC should refer to the sum of activities derived from active enzymatic antioxidant systems (e.g. superoxide dismutase, catalase, glutathione peroxidase etc.), nonenzymatic antioxidants, such as vitamins C and E, and the presence of other bioactive factors (e.g. lactoferrin, uric acid etc.). Measuring oxidation-reduction potential (ORP) using RedoxSYS Analyzer may be an alternative to classic methods of measuring TAC. We compared the results of OPR and ascorbic acid content in milk from mothers of preterm infants. Method Milk was obtained from ten mothers of preterm infants (gestational age 28-36 weeks; birth weight 900-2,470 g). Milk samples were obtained within the first 4 days after delivery (colostrum), from day 4 to two weeks (transient),  and 6 weeks and later (mature milk). Static oxidation−reduction potential (ORP) of milk from mothers of preterm infants was measured using RedoxSYS Analyzer (Luoxis Diagnostics, Englewood, CO). Ascorbic acid content was measured in milk samples and results were expressed as mg/l. Procedure suggested by the manufacturer was used (Reflect quant® ascorbic acid test for reflectometerRQflex®, Merck KGaA, Germany, 2006). Results There are similarities in the results of OPR and vitamin C concentration in colostrum, transient and mature milk from mothers of preterm infants. Conclusion Vitamin C concentration influenced the value of OPR most.",
publisher = "International Conferences on Nutrition & Growth",
journal = "3rd International Conference on Nutrition & Growth, March 17-19, 2016, Vienna, Austria",
title = "Oxidation-reduction potential in the milk from mothers of preterm infants",
pages = "110",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2940"
}

Spasic, S., Miletic, S., Minić, S., Lugonja, N., Marinković, V., Spasojević, I.,& Vrvic, M.. (2016). Oxidation-reduction potential in the milk from mothers of preterm infants. in 3rd International Conference on Nutrition & Growth, March 17-19, 2016, Vienna, Austria
International Conferences on Nutrition & Growth., 110.
https://hdl.handle.net/21.15107/rcub_rimsi_2940

Spasic S, Miletic S, Minić S, Lugonja N, Marinković V, Spasojević I, Vrvic M. Oxidation-reduction potential in the milk from mothers of preterm infants. in 3rd International Conference on Nutrition & Growth, March 17-19, 2016, Vienna, Austria. 2016;:110.
https://hdl.handle.net/21.15107/rcub_rimsi_2940 .

Spasic, Snezana, Miletic, Srdjan, Minić, Simeon, Lugonja, Nikoleta, Marinković, Vesna, Spasojević, Ivan, Vrvic, Miroslav, "Oxidation-reduction potential in the milk from mothers of preterm infants" in 3rd International Conference on Nutrition & Growth, March 17-19, 2016, Vienna, Austria (2016):110,
https://hdl.handle.net/21.15107/rcub_rimsi_2940 .

TY  - JOUR
AU  - Marinković, Vesna
AU  - Rankovic-Janevski, Milica
AU  - Spasic, Snežana
AU  - Nikolić-Kokić, Aleksandra
AU  - Lugonja, Nikoleta
AU  - Djurović, Dijana
AU  - Miletic, Srdjan
AU  - Vrvić, Miroslav M.
AU  - Spasojević, Ivan
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/974
AB  - Objectives: Milk banks collect, pasteurize, and freeze/store human milk. The processing may alter redox properties of milk, but the effects have not been fully examined. Methods: We collected 10 mature milk and 10 colostrum samples and applied a battery of biochemical assays and electron paramagnetic resonance spectroscopy to inspect changes that milk undergoes with pasteurization and 30 days storage at -20 degrees C. Results: Pasteurization and storage of raw milk did not affect total nonenzymatic antioxidative capacity, but specific components and features were altered. Urate radical and ascorbyl radical emerge as products of exposure of milk to hydroxyl radical-generating system. Processing shifted the load of antioxidative activity from ascorbate to urate and lowered the capacity of milk to diminish hydroxyl radical. Pasteurization caused a significant drop in the activity of 2 major antioxidative enzymes-superoxide dismutase and glutathione peroxidase, whereas freezing/storage of raw milk affected only superoxide dismutase. Colostrum showed drastically higher total nonenzymatic antioxidative capacity, hydroxyl radical scavenging ability, and glutathione reductase activity compared with mature milk. Conclusions: Pasteurization and storage affect nonenzymatic and enzymatic antioxidative agents in human milk. It appears that nonenzymatic antioxidative systems in colostrum and milk are different. The effects of processing may be partially compensated by fortification/spiking with ascorbate before use.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Journal of Pediatric Gastroenterology and Nutrition
T1  - Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage
EP  - 906
IS  - 6
SP  - 901
VL  - 62
DO  - 10.1097/MPG.0000000000001090
ER  - 

@article{
author = "Marinković, Vesna and Rankovic-Janevski, Milica and Spasic, Snežana and Nikolić-Kokić, Aleksandra and Lugonja, Nikoleta and Djurović, Dijana and Miletic, Srdjan and Vrvić, Miroslav M. and Spasojević, Ivan",
year = "2016",
abstract = "Objectives: Milk banks collect, pasteurize, and freeze/store human milk. The processing may alter redox properties of milk, but the effects have not been fully examined. Methods: We collected 10 mature milk and 10 colostrum samples and applied a battery of biochemical assays and electron paramagnetic resonance spectroscopy to inspect changes that milk undergoes with pasteurization and 30 days storage at -20 degrees C. Results: Pasteurization and storage of raw milk did not affect total nonenzymatic antioxidative capacity, but specific components and features were altered. Urate radical and ascorbyl radical emerge as products of exposure of milk to hydroxyl radical-generating system. Processing shifted the load of antioxidative activity from ascorbate to urate and lowered the capacity of milk to diminish hydroxyl radical. Pasteurization caused a significant drop in the activity of 2 major antioxidative enzymes-superoxide dismutase and glutathione peroxidase, whereas freezing/storage of raw milk affected only superoxide dismutase. Colostrum showed drastically higher total nonenzymatic antioxidative capacity, hydroxyl radical scavenging ability, and glutathione reductase activity compared with mature milk. Conclusions: Pasteurization and storage affect nonenzymatic and enzymatic antioxidative agents in human milk. It appears that nonenzymatic antioxidative systems in colostrum and milk are different. The effects of processing may be partially compensated by fortification/spiking with ascorbate before use.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
title = "Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage",
pages = "906-901",
number = "6",
volume = "62",
doi = "10.1097/MPG.0000000000001090"
}

Marinković, V., Rankovic-Janevski, M., Spasic, S., Nikolić-Kokić, A., Lugonja, N., Djurović, D., Miletic, S., Vrvić, M. M.,& Spasojević, I.. (2016). Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage. in Journal of Pediatric Gastroenterology and Nutrition
Lippincott Williams & Wilkins, Philadelphia., 62(6), 901-906.
https://doi.org/10.1097/MPG.0000000000001090

Marinković V, Rankovic-Janevski M, Spasic S, Nikolić-Kokić A, Lugonja N, Djurović D, Miletic S, Vrvić MM, Spasojević I. Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage. in Journal of Pediatric Gastroenterology and Nutrition. 2016;62(6):901-906.
doi:10.1097/MPG.0000000000001090 .

Marinković, Vesna, Rankovic-Janevski, Milica, Spasic, Snežana, Nikolić-Kokić, Aleksandra, Lugonja, Nikoleta, Djurović, Dijana, Miletic, Srdjan, Vrvić, Miroslav M., Spasojević, Ivan, "Antioxidative Activity of Colostrum and Human Milk: Effects of Pasteurization and Storage" in Journal of Pediatric Gastroenterology and Nutrition, 62, no. 6 (2016):901-906,
https://doi.org/10.1097/MPG.0000000000001090 . .

TY  - CONF
AU  - Vrvic, Miroslav
AU  - Miletic, Srdjan
AU  - Lugonja, Nikoleta
AU  - Spasic, Snezana
AU  - Marinković, Vesna
AU  - Rankovic-Janevski, Milica
AU  - Spasojević, Ivan
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2878
AB  - Mothers milk have antioxidative effects against Fenton system via HO radical scavenging. Mother's milk from woman's after preterm delivery antioxidative properties are not examined in details. We examined hydroxil radical scavenging activity of preterm mothers milks in the Fenton system.
PB  - Bulgarian Food Safety Agency
C3  - 2nd National Food Conference, March 20th -21st, 2015, Sofia, Bulgaria
T1  - Hydroxil Radical Scavenging Activity of Preterm Mothers Milks in the Fenton System
SP  - 43
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2878
ER  - 

@conference{
author = "Vrvic, Miroslav and Miletic, Srdjan and Lugonja, Nikoleta and Spasic, Snezana and Marinković, Vesna and Rankovic-Janevski, Milica and Spasojević, Ivan",
year = "2015",
abstract = "Mothers milk have antioxidative effects against Fenton system via HO radical scavenging. Mother's milk from woman's after preterm delivery antioxidative properties are not examined in details. We examined hydroxil radical scavenging activity of preterm mothers milks in the Fenton system.",
publisher = "Bulgarian Food Safety Agency",
journal = "2nd National Food Conference, March 20th -21st, 2015, Sofia, Bulgaria",
title = "Hydroxil Radical Scavenging Activity of Preterm Mothers Milks in the Fenton System",
pages = "43",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2878"
}

Vrvic, M., Miletic, S., Lugonja, N., Spasic, S., Marinković, V., Rankovic-Janevski, M.,& Spasojević, I.. (2015). Hydroxil Radical Scavenging Activity of Preterm Mothers Milks in the Fenton System. in 2nd National Food Conference, March 20th -21st, 2015, Sofia, Bulgaria
Bulgarian Food Safety Agency., 43.
https://hdl.handle.net/21.15107/rcub_rimsi_2878

Vrvic M, Miletic S, Lugonja N, Spasic S, Marinković V, Rankovic-Janevski M, Spasojević I. Hydroxil Radical Scavenging Activity of Preterm Mothers Milks in the Fenton System. in 2nd National Food Conference, March 20th -21st, 2015, Sofia, Bulgaria. 2015;:43.
https://hdl.handle.net/21.15107/rcub_rimsi_2878 .

Vrvic, Miroslav, Miletic, Srdjan, Lugonja, Nikoleta, Spasic, Snezana, Marinković, Vesna, Rankovic-Janevski, Milica, Spasojević, Ivan, "Hydroxil Radical Scavenging Activity of Preterm Mothers Milks in the Fenton System" in 2nd National Food Conference, March 20th -21st, 2015, Sofia, Bulgaria (2015):43,
https://hdl.handle.net/21.15107/rcub_rimsi_2878 .