TY  - JOUR
AU  - Nikolic, Milos MN
AU  - Marković, Tatjana
AU  - Mojović, Miloš
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Peric, Tamara O
AU  - Marković, Dejan Lj
AU  - Stević, Tatjana R
AU  - Soković, Marina
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/675
AB  - The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops and Products
T1  - Chemical composition and biological activity of Gaultheria procumbens L. essential oil
EP  - 567
SP  - 561
VL  - 49
DO  - 10.1016/j.indcrop.2013.06.002
ER  - 

@article{
author = "Nikolic, Milos MN and Marković, Tatjana and Mojović, Miloš and Pejin, Boris and Savić, Aleksandar G and Peric, Tamara O and Marković, Dejan Lj and Stević, Tatjana R and Soković, Marina",
year = "2013",
abstract = "The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops and Products",
title = "Chemical composition and biological activity of Gaultheria procumbens L. essential oil",
pages = "567-561",
volume = "49",
doi = "10.1016/j.indcrop.2013.06.002"
}

Nikolic, M. M., Marković, T., Mojović, M., Pejin, B., Savić, A. G., Peric, T. O., Marković, D. L., Stević, T. R.,& Soković, M.. (2013). Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products
Elsevier, Amsterdam., 49, 561-567.
https://doi.org/10.1016/j.indcrop.2013.06.002

Nikolic MM, Marković T, Mojović M, Pejin B, Savić AG, Peric TO, Marković DL, Stević TR, Soković M. Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products. 2013;49:561-567.
doi:10.1016/j.indcrop.2013.06.002 .

Nikolic, Milos MN, Marković, Tatjana, Mojović, Miloš, Pejin, Boris, Savić, Aleksandar G, Peric, Tamara O, Marković, Dejan Lj, Stević, Tatjana R, Soković, Marina, "Chemical composition and biological activity of Gaultheria procumbens L. essential oil" in Industrial Crops and Products, 49 (2013):561-567,
https://doi.org/10.1016/j.indcrop.2013.06.002 . .

TY  - CONF
AU  - Kostić, Miroslav
AU  - Kostić, Igor
AU  - Marković, Tatjana
AU  - Jevđović, Radosav
AU  - Stanković, Slađan
AU  - Todorović, Goran
AU  - Nedić, Nebojša
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2803
AB  - Colorado potato beetle has a very high reproductive potential in Serbia due to favorable
climatic conditions and nutrition. Considering that it is an introduced species, the activity of
limiting biotic factors seems negligible. With the time, it developed resistance on commercial
insecticides, and consequently they cease to be used for this purpose. In recent years, not only
in the EU, a strong public pressure has been posed on production of safe food, i.e. food with
no pesticide residues which are harmful and dangerous to human health. For these reasons,
today we examine several alternative routes, such as: the creation of resistant potato varieties
(transgenic potatoes), joint cultivation of potatoes with plants with efficacy to repel or
confuse the potato beetle. A great number of herbal extracts and essential oil has been studied
so far in order to find natural solution that will replace conventional insecticides. In this
study, the possibility to disrupt the attractant properties of potato leaf on Colorado potato
beetles, by application of 95% ethanol solutions of sage essential oil and its fractions (F1-F5)
(0.5% concentration) was examined. Chemical composition of sage essential oil and its five
fractions used in experiment was presented. Tests were conducted at the Adult (female)
Leptinotarsa decemlineata Say in the olfactometer. The experiments were set up in five
replicates, in micro-climatic chamber, with following constant conditions: temperature 27°C
± 1°C, relative humidity 65% ± 5% and the illumination was 9400p cd. Results were
processed by the use of Analysis of variance and Duncan’s test. The most pronounced
disturbance was recorded with application of sage essential oil and the least one was achieved
with application of the fraction one (F1). The obtained results indicate possibility of using
secondary metabolites of Salvia officinalis L. in protection of potato foliage of its major pest
(L. decemlineata).
PB  - Association for Medicinal and Aromatic Plants of Southeast European Countries (AMAPSEEC) & Institute for Medicinal Plant Research “Dr Josif Pančić”, Belgrade, Srbija
C3  - Proceedings of the Seventh Conference on Medicinal and Aromatic Plants of Southeast European Countries
T1  - Disruption of attractant properties of potato foliage on Leptinotarsa decemlineata Say by the use of Salvia officinalis L. essential oil
VL  - 7
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2803
ER  - 

@conference{
author = "Kostić, Miroslav and Kostić, Igor and Marković, Tatjana and Jevđović, Radosav and Stanković, Slađan and Todorović, Goran and Nedić, Nebojša",
year = "2012",
abstract = "Colorado potato beetle has a very high reproductive potential in Serbia due to favorable
climatic conditions and nutrition. Considering that it is an introduced species, the activity of
limiting biotic factors seems negligible. With the time, it developed resistance on commercial
insecticides, and consequently they cease to be used for this purpose. In recent years, not only
in the EU, a strong public pressure has been posed on production of safe food, i.e. food with
no pesticide residues which are harmful and dangerous to human health. For these reasons,
today we examine several alternative routes, such as: the creation of resistant potato varieties
(transgenic potatoes), joint cultivation of potatoes with plants with efficacy to repel or
confuse the potato beetle. A great number of herbal extracts and essential oil has been studied
so far in order to find natural solution that will replace conventional insecticides. In this
study, the possibility to disrupt the attractant properties of potato leaf on Colorado potato
beetles, by application of 95% ethanol solutions of sage essential oil and its fractions (F1-F5)
(0.5% concentration) was examined. Chemical composition of sage essential oil and its five
fractions used in experiment was presented. Tests were conducted at the Adult (female)
Leptinotarsa decemlineata Say in the olfactometer. The experiments were set up in five
replicates, in micro-climatic chamber, with following constant conditions: temperature 27°C
± 1°C, relative humidity 65% ± 5% and the illumination was 9400p cd. Results were
processed by the use of Analysis of variance and Duncan’s test. The most pronounced
disturbance was recorded with application of sage essential oil and the least one was achieved
with application of the fraction one (F1). The obtained results indicate possibility of using
secondary metabolites of Salvia officinalis L. in protection of potato foliage of its major pest
(L. decemlineata).",
publisher = "Association for Medicinal and Aromatic Plants of Southeast European Countries (AMAPSEEC) & Institute for Medicinal Plant Research “Dr Josif Pančić”, Belgrade, Srbija",
journal = "Proceedings of the Seventh Conference on Medicinal and Aromatic Plants of Southeast European Countries",
title = "Disruption of attractant properties of potato foliage on Leptinotarsa decemlineata Say by the use of Salvia officinalis L. essential oil",
volume = "7",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2803"
}

Kostić, M., Kostić, I., Marković, T., Jevđović, R., Stanković, S., Todorović, G.,& Nedić, N.. (2012). Disruption of attractant properties of potato foliage on Leptinotarsa decemlineata Say by the use of Salvia officinalis L. essential oil. in Proceedings of the Seventh Conference on Medicinal and Aromatic Plants of Southeast European Countries
Association for Medicinal and Aromatic Plants of Southeast European Countries (AMAPSEEC) & Institute for Medicinal Plant Research “Dr Josif Pančić”, Belgrade, Srbija., 7.
https://hdl.handle.net/21.15107/rcub_rimsi_2803

Kostić M, Kostić I, Marković T, Jevđović R, Stanković S, Todorović G, Nedić N. Disruption of attractant properties of potato foliage on Leptinotarsa decemlineata Say by the use of Salvia officinalis L. essential oil. in Proceedings of the Seventh Conference on Medicinal and Aromatic Plants of Southeast European Countries. 2012;7.
https://hdl.handle.net/21.15107/rcub_rimsi_2803 .

Kostić, Miroslav, Kostić, Igor, Marković, Tatjana, Jevđović, Radosav, Stanković, Slađan, Todorović, Goran, Nedić, Nebojša, "Disruption of attractant properties of potato foliage on Leptinotarsa decemlineata Say by the use of Salvia officinalis L. essential oil" in Proceedings of the Seventh Conference on Medicinal and Aromatic Plants of Southeast European Countries, 7 (2012),
https://hdl.handle.net/21.15107/rcub_rimsi_2803 .