TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Kien-Thai, Yong
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/756
AB  - The moss Rhodobryum ontariense tea has been claimed by Traditional Chinese medicine for its beneficial effects in the treatment of wide range of cardiovascular diseases including hypertension. The antiradical activity of R. ontariense tea (L e. its lyophilised water extract) was evaluated by electron paramagnetic resonance spectroscopy/against superoxide anion(center dot O-2(-)), nitric-oxide (center dot NO), 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH), carbon-dioxide anion (center dot CO2-) and methoxy (center dot CH2OH) radicals/ and fluorescence spectroscopy/against hydroxyl (center dot OH) radicals/ in in vitro conditions. It reduced the production of majority of radical species tested, but in a varying degree. The most activity was observed against center dot OH, center dot DPPH and center dot CO2- radicals (95 +/- 10%, 78 +/- 4% and 67 +/- 5%, respectively). In addition, the extract was shown to be active against center dot CH2OH and center dot NO radicals (55 +/- 8% and 45 +/- 8%, respectively). On the contrary, no any antiradical activity was observed against center dot O(2)(-)radicals. According to the experimental data obtained, R. ontariense tea can be considered as a promising resource of natural products with antiradical activity and may be of some interest to research in heart disease.
PB  - Adac-Cryptogamie, Paris
T2  - Cryptogamie Bryologie
T1  - Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy
EP  - 179
IS  - 2
SP  - 173
VL  - 35
DO  - 10.7872/cryb.v35.iss2.2014.173
ER  - 

@article{
author = "Pejin, Boris and Savić, Aleksandar G and Kien-Thai, Yong and Mojović, Miloš",
year = "2014",
abstract = "The moss Rhodobryum ontariense tea has been claimed by Traditional Chinese medicine for its beneficial effects in the treatment of wide range of cardiovascular diseases including hypertension. The antiradical activity of R. ontariense tea (L e. its lyophilised water extract) was evaluated by electron paramagnetic resonance spectroscopy/against superoxide anion(center dot O-2(-)), nitric-oxide (center dot NO), 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH), carbon-dioxide anion (center dot CO2-) and methoxy (center dot CH2OH) radicals/ and fluorescence spectroscopy/against hydroxyl (center dot OH) radicals/ in in vitro conditions. It reduced the production of majority of radical species tested, but in a varying degree. The most activity was observed against center dot OH, center dot DPPH and center dot CO2- radicals (95 +/- 10%, 78 +/- 4% and 67 +/- 5%, respectively). In addition, the extract was shown to be active against center dot CH2OH and center dot NO radicals (55 +/- 8% and 45 +/- 8%, respectively). On the contrary, no any antiradical activity was observed against center dot O(2)(-)radicals. According to the experimental data obtained, R. ontariense tea can be considered as a promising resource of natural products with antiradical activity and may be of some interest to research in heart disease.",
publisher = "Adac-Cryptogamie, Paris",
journal = "Cryptogamie Bryologie",
title = "Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy",
pages = "179-173",
number = "2",
volume = "35",
doi = "10.7872/cryb.v35.iss2.2014.173"
}

Pejin, B., Savić, A. G., Kien-Thai, Y.,& Mojović, M.. (2014). Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy. in Cryptogamie Bryologie
Adac-Cryptogamie, Paris., 35(2), 173-179.
https://doi.org/10.7872/cryb.v35.iss2.2014.173

Pejin B, Savić AG, Kien-Thai Y, Mojović M. Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy. in Cryptogamie Bryologie. 2014;35(2):173-179.
doi:10.7872/cryb.v35.iss2.2014.173 .

Pejin, Boris, Savić, Aleksandar G, Kien-Thai, Yong, Mojović, Miloš, "Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy" in Cryptogamie Bryologie, 35, no. 2 (2014):173-179,
https://doi.org/10.7872/cryb.v35.iss2.2014.173 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Belic, D.
AU  - Vucković, G.
AU  - Kien-Thai, Yong
AU  - Stanimirović, Bojana
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/649
AB  - The content of sodium, potassium, magnesium, calcium, selenium, phosphorus, nitrite and nitrate in the moss Rhodobryum ontariense and its tea was investigated for medicinal reason. The aim of this study was preliminary estimation of R. ontariense minerals' contribution to the treatment of hypertension, claimed for the moss tea by Traditional Chinese Medicine. Majority of cations were determined by EPA methods, while phosphorus was determined with an appropriate ISO method. The anions nitrite and nitrate were determined by ion chromatography. Potassium was the most abundant mineral in the investigated tea (5895.20 +/- 1.22 mg/kg) and might be speculated as one of its beneficial ingredients for the treatment of elevated blood pressure conditions.
PB  - Codon Publications
T2  - Italian Journal of Food Science
T1  - Mineral content of a moss tea for hypertension
EP  - 237
IS  - 2
SP  - 235
VL  - 25
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_649
ER  - 

@article{
author = "Pejin, Boris and Belic, D. and Vucković, G. and Kien-Thai, Yong and Stanimirović, Bojana",
year = "2013",
abstract = "The content of sodium, potassium, magnesium, calcium, selenium, phosphorus, nitrite and nitrate in the moss Rhodobryum ontariense and its tea was investigated for medicinal reason. The aim of this study was preliminary estimation of R. ontariense minerals' contribution to the treatment of hypertension, claimed for the moss tea by Traditional Chinese Medicine. Majority of cations were determined by EPA methods, while phosphorus was determined with an appropriate ISO method. The anions nitrite and nitrate were determined by ion chromatography. Potassium was the most abundant mineral in the investigated tea (5895.20 +/- 1.22 mg/kg) and might be speculated as one of its beneficial ingredients for the treatment of elevated blood pressure conditions.",
publisher = "Codon Publications",
journal = "Italian Journal of Food Science",
title = "Mineral content of a moss tea for hypertension",
pages = "237-235",
number = "2",
volume = "25",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_649"
}

Pejin, B., Belic, D., Vucković, G., Kien-Thai, Y.,& Stanimirović, B.. (2013). Mineral content of a moss tea for hypertension. in Italian Journal of Food Science
Codon Publications., 25(2), 235-237.
https://hdl.handle.net/21.15107/rcub_rimsi_649

Pejin B, Belic D, Vucković G, Kien-Thai Y, Stanimirović B. Mineral content of a moss tea for hypertension. in Italian Journal of Food Science. 2013;25(2):235-237.
https://hdl.handle.net/21.15107/rcub_rimsi_649 .

Pejin, Boris, Belic, D., Vucković, G., Kien-Thai, Yong, Stanimirović, Bojana, "Mineral content of a moss tea for hypertension" in Italian Journal of Food Science, 25, no. 2 (2013):235-237,
https://hdl.handle.net/21.15107/rcub_rimsi_649 .

TY  - JOUR
AU  - Pejin, Boris
AU  - Tovilović, Gordana I
AU  - Ignjatović, Djurdjica S
AU  - Kien-Thai, Yong
AU  - Tomic, Mirko D
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/635
AB  - This is the first study designed to explore behavioral effects of the water extract of the moss Rhodobryum ontariense (ROE). Experimental adult animals received intraperitoneal injections of ROE (50-400 mg/kg; vs. saline) 45 min before behavioural evaluation. Motor effects of ROE were estimated in male mice using the open field test (OFT), whereas the elevated plus maze (EPM) model of anxiety was applied on male rats. Single ROE treatments significantly decreased motor activity of mice in OFT (p lt 0.001) by reducing both the percentage of activity time and the distance travelled in 15 min Also, ROE in rats significantly increased (p lt 0.05) the percentage of time spent in open arms and the number of open-arm-entries during 5 min, which was similar to the actions of diazepam in rats (1 mg/kg). These results demonstrated that ROE produced motor sedation and anxiolytic-like effects in rodents.
PB  - Adac-Cryptogamie, Paris
T2  - Cryptogamie Bryologie
T1  - Sedative and anxiolytic-like activities of the moss Rhodobryum ontariense water extract in rodents: a preliminary study
EP  - 54
IS  - 1
SP  - 49
VL  - 34
DO  - 10.7872/cryb.v34.iss1.2013.49
ER  - 

@article{
author = "Pejin, Boris and Tovilović, Gordana I and Ignjatović, Djurdjica S and Kien-Thai, Yong and Tomic, Mirko D",
year = "2013",
abstract = "This is the first study designed to explore behavioral effects of the water extract of the moss Rhodobryum ontariense (ROE). Experimental adult animals received intraperitoneal injections of ROE (50-400 mg/kg; vs. saline) 45 min before behavioural evaluation. Motor effects of ROE were estimated in male mice using the open field test (OFT), whereas the elevated plus maze (EPM) model of anxiety was applied on male rats. Single ROE treatments significantly decreased motor activity of mice in OFT (p lt 0.001) by reducing both the percentage of activity time and the distance travelled in 15 min Also, ROE in rats significantly increased (p lt 0.05) the percentage of time spent in open arms and the number of open-arm-entries during 5 min, which was similar to the actions of diazepam in rats (1 mg/kg). These results demonstrated that ROE produced motor sedation and anxiolytic-like effects in rodents.",
publisher = "Adac-Cryptogamie, Paris",
journal = "Cryptogamie Bryologie",
title = "Sedative and anxiolytic-like activities of the moss Rhodobryum ontariense water extract in rodents: a preliminary study",
pages = "54-49",
number = "1",
volume = "34",
doi = "10.7872/cryb.v34.iss1.2013.49"
}

Pejin, B., Tovilović, G. I., Ignjatović, D. S., Kien-Thai, Y.,& Tomic, M. D.. (2013). Sedative and anxiolytic-like activities of the moss Rhodobryum ontariense water extract in rodents: a preliminary study. in Cryptogamie Bryologie
Adac-Cryptogamie, Paris., 34(1), 49-54.
https://doi.org/10.7872/cryb.v34.iss1.2013.49

Pejin B, Tovilović GI, Ignjatović DS, Kien-Thai Y, Tomic MD. Sedative and anxiolytic-like activities of the moss Rhodobryum ontariense water extract in rodents: a preliminary study. in Cryptogamie Bryologie. 2013;34(1):49-54.
doi:10.7872/cryb.v34.iss1.2013.49 .

Pejin, Boris, Tovilović, Gordana I, Ignjatović, Djurdjica S, Kien-Thai, Yong, Tomic, Mirko D, "Sedative and anxiolytic-like activities of the moss Rhodobryum ontariense water extract in rodents: a preliminary study" in Cryptogamie Bryologie, 34, no. 1 (2013):49-54,
https://doi.org/10.7872/cryb.v34.iss1.2013.49 . .

TY  - JOUR
AU  - Pejin, Boris
AU  - Kien-Thai, Yong
AU  - Bogdanović Pristov, Jelena
AU  - Pejin, I.
AU  - Spasojević, Ivan
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/598
AB  - The ability to modulate erythrocyte membrane fluidity, the capacity to release nitric oxide and the ABTS [2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)] cation scavenging activity including the total phenolic content screening of the moss Rhodobryum ontariense tea, a traditional Chinese herbal medicine for hypertension and a wide range of cardiovascular diseases, were conducted in vitro in this study. This medicinal tea did not affect human erythrocyte membrane fluidity, did not contain reservoir of nitric oxide to be eliminated in blood and it showed low ABTS cation scavenging activity including meager content of total phenolic compounds. The obtained results excluded in a great extent some possible mechanisms of action of R. ontariense tea in relation to highlighted medical conditions.
PB  - Inst Materials Physics
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - In vitro investigation of the antihypertensive effect of the moss rhodobryum ontariense (kindb.) (kindb.)
EP  - 359
IS  - 1
SP  - 353
VL  - 7
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_598
ER  - 

@article{
author = "Pejin, Boris and Kien-Thai, Yong and Bogdanović Pristov, Jelena and Pejin, I. and Spasojević, Ivan",
year = "2012",
abstract = "The ability to modulate erythrocyte membrane fluidity, the capacity to release nitric oxide and the ABTS [2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid)] cation scavenging activity including the total phenolic content screening of the moss Rhodobryum ontariense tea, a traditional Chinese herbal medicine for hypertension and a wide range of cardiovascular diseases, were conducted in vitro in this study. This medicinal tea did not affect human erythrocyte membrane fluidity, did not contain reservoir of nitric oxide to be eliminated in blood and it showed low ABTS cation scavenging activity including meager content of total phenolic compounds. The obtained results excluded in a great extent some possible mechanisms of action of R. ontariense tea in relation to highlighted medical conditions.",
publisher = "Inst Materials Physics",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "In vitro investigation of the antihypertensive effect of the moss rhodobryum ontariense (kindb.) (kindb.)",
pages = "359-353",
number = "1",
volume = "7",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_598"
}

Pejin, B., Kien-Thai, Y., Bogdanović Pristov, J., Pejin, I.,& Spasojević, I.. (2012). In vitro investigation of the antihypertensive effect of the moss rhodobryum ontariense (kindb.) (kindb.). in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics., 7(1), 353-359.
https://hdl.handle.net/21.15107/rcub_rimsi_598

Pejin B, Kien-Thai Y, Bogdanović Pristov J, Pejin I, Spasojević I. In vitro investigation of the antihypertensive effect of the moss rhodobryum ontariense (kindb.) (kindb.). in Digest Journal of Nanomaterials and Biostructures. 2012;7(1):353-359.
https://hdl.handle.net/21.15107/rcub_rimsi_598 .

Pejin, Boris, Kien-Thai, Yong, Bogdanović Pristov, Jelena, Pejin, I., Spasojević, Ivan, "In vitro investigation of the antihypertensive effect of the moss rhodobryum ontariense (kindb.) (kindb.)" in Digest Journal of Nanomaterials and Biostructures, 7, no. 1 (2012):353-359,
https://hdl.handle.net/21.15107/rcub_rimsi_598 .

TY  - JOUR
AU  - Pejin, Boris
AU  - Kien-Thai, Yong
AU  - Stanimirović, Bojana
AU  - Vucković, Gordana N
AU  - Belic, Danijela
AU  - Sabovljević, Marko S
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/593
AB  - The content of various heavy metals (arsenic, cadmium, chromium, copper, iron, lead, mercury, nickel, manganese and zinc) in the moss species Rhodobryum ontariense (Kindb.) Kindb. and its tea are presented in this study. Pursuant to the use of this tea in traditional Chinese medicine for hypertension, the aim of this study was to examine its safety in regard to the metals. All heavy metals were determined by adequate EPA methods. The concentrations of all metals for daily intake in its tea were below the safety levels for human consumption. These results indicate the importance of manganese in R. ontariense tea traditionally used for hypertension and other heart disorders.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Heavy metal content of a medicinal moss tea for hypertension
EP  - 2242
IS  - 23
SP  - 2239
VL  - 26
DO  - 10.1080/14786419.2011.648190
ER  - 

@article{
author = "Pejin, Boris and Kien-Thai, Yong and Stanimirović, Bojana and Vucković, Gordana N and Belic, Danijela and Sabovljević, Marko S",
year = "2012",
abstract = "The content of various heavy metals (arsenic, cadmium, chromium, copper, iron, lead, mercury, nickel, manganese and zinc) in the moss species Rhodobryum ontariense (Kindb.) Kindb. and its tea are presented in this study. Pursuant to the use of this tea in traditional Chinese medicine for hypertension, the aim of this study was to examine its safety in regard to the metals. All heavy metals were determined by adequate EPA methods. The concentrations of all metals for daily intake in its tea were below the safety levels for human consumption. These results indicate the importance of manganese in R. ontariense tea traditionally used for hypertension and other heart disorders.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Heavy metal content of a medicinal moss tea for hypertension",
pages = "2242-2239",
number = "23",
volume = "26",
doi = "10.1080/14786419.2011.648190"
}

Pejin, B., Kien-Thai, Y., Stanimirović, B., Vucković, G. N., Belic, D.,& Sabovljević, M. S.. (2012). Heavy metal content of a medicinal moss tea for hypertension. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 26(23), 2239-2242.
https://doi.org/10.1080/14786419.2011.648190

Pejin B, Kien-Thai Y, Stanimirović B, Vucković GN, Belic D, Sabovljević MS. Heavy metal content of a medicinal moss tea for hypertension. in Natural Product Research. 2012;26(23):2239-2242.
doi:10.1080/14786419.2011.648190 .

Pejin, Boris, Kien-Thai, Yong, Stanimirović, Bojana, Vucković, Gordana N, Belic, Danijela, Sabovljević, Marko S, "Heavy metal content of a medicinal moss tea for hypertension" in Natural Product Research, 26, no. 23 (2012):2239-2242,
https://doi.org/10.1080/14786419.2011.648190 . .