TY  - CONF
AU  - Lukičić, Jovana
AU  - Rodić, Ivanka
AU  - Žižić, Milan
AU  - Zakrzewska, Joanna
AU  - Cvetic Antic, Tijana
AU  - Živić, Miroslav
AU  - Stanić, Marina
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2418
AB  - Vanadium enters mycelium of fungus P. blakesleeanus in both +5 and +4 oxidation states. Mycelium in three stages of growth (20h, 36h and 56h) was treated with three concentrations of V+5 (1, 5 and 10 mM) for 1h or 5h. The decrease in viability of mycelium was noticed only at 36h for all applied concentrations. Glutathione has a role in reduction of V+5 to a less toxic form V+4 , so we assayed the changes in total glutathione. Mycelium in early exponential phase of growth (20 h), after 1h or 5h treatment, showed concentration dependent decrease in glutathione, with the largest decrease of 40±4% after 1h and 22±9% after 5h treatment induced by 10 mM V+5. In stationary phase of growth (56h), changes in glutathione concentration were noticed only after 1h of treatment, and the largest decrease (36±6%) was induced by 1 mM V+5. Activities of glutathione reductase (GR), glutathione transferase (GST) and glutathione peroxidase (GPx), have also been examined. Increase in the activities of GPx and GST was noticed in 56h old mycelia treated for 5h with 5 mM and 10 mM V+5, but the only statistically significant increase (54±20%) was noticed in GST activity after 5h of 10 mM V+5 treatment.
PB  - Faculty of Chemistry, Serbian Biochemical Society
C3  - Serbian Biochemical Society Ninth Conference, “Diversity in Biochemistry”. 14-16.11.2019. Belgrade, Serbia
T1  - Effects of vanadate on glutathione metabolism in mycelium of fungus Phycomyces blakesleeanus
EP  - 118
SP  - 118
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2418
ER  - 

@conference{
author = "Lukičić, Jovana and Rodić, Ivanka and Žižić, Milan and Zakrzewska, Joanna and Cvetic Antic, Tijana and Živić, Miroslav and Stanić, Marina",
year = "2019",
abstract = "Vanadium enters mycelium of fungus P. blakesleeanus in both +5 and +4 oxidation states. Mycelium in three stages of growth (20h, 36h and 56h) was treated with three concentrations of V+5 (1, 5 and 10 mM) for 1h or 5h. The decrease in viability of mycelium was noticed only at 36h for all applied concentrations. Glutathione has a role in reduction of V+5 to a less toxic form V+4 , so we assayed the changes in total glutathione. Mycelium in early exponential phase of growth (20 h), after 1h or 5h treatment, showed concentration dependent decrease in glutathione, with the largest decrease of 40±4% after 1h and 22±9% after 5h treatment induced by 10 mM V+5. In stationary phase of growth (56h), changes in glutathione concentration were noticed only after 1h of treatment, and the largest decrease (36±6%) was induced by 1 mM V+5. Activities of glutathione reductase (GR), glutathione transferase (GST) and glutathione peroxidase (GPx), have also been examined. Increase in the activities of GPx and GST was noticed in 56h old mycelia treated for 5h with 5 mM and 10 mM V+5, but the only statistically significant increase (54±20%) was noticed in GST activity after 5h of 10 mM V+5 treatment.",
publisher = "Faculty of Chemistry, Serbian Biochemical Society",
journal = "Serbian Biochemical Society Ninth Conference, “Diversity in Biochemistry”. 14-16.11.2019. Belgrade, Serbia",
title = "Effects of vanadate on glutathione metabolism in mycelium of fungus Phycomyces blakesleeanus",
pages = "118-118",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2418"
}

Lukičić, J., Rodić, I., Žižić, M., Zakrzewska, J., Cvetic Antic, T., Živić, M.,& Stanić, M.. (2019). Effects of vanadate on glutathione metabolism in mycelium of fungus Phycomyces blakesleeanus. in Serbian Biochemical Society Ninth Conference, “Diversity in Biochemistry”. 14-16.11.2019. Belgrade, Serbia
Faculty of Chemistry, Serbian Biochemical Society., 118-118.
https://hdl.handle.net/21.15107/rcub_rimsi_2418

Lukičić J, Rodić I, Žižić M, Zakrzewska J, Cvetic Antic T, Živić M, Stanić M. Effects of vanadate on glutathione metabolism in mycelium of fungus Phycomyces blakesleeanus. in Serbian Biochemical Society Ninth Conference, “Diversity in Biochemistry”. 14-16.11.2019. Belgrade, Serbia. 2019;:118-118.
https://hdl.handle.net/21.15107/rcub_rimsi_2418 .

Lukičić, Jovana, Rodić, Ivanka, Žižić, Milan, Zakrzewska, Joanna, Cvetic Antic, Tijana, Živić, Miroslav, Stanić, Marina, "Effects of vanadate on glutathione metabolism in mycelium of fungus Phycomyces blakesleeanus" in Serbian Biochemical Society Ninth Conference, “Diversity in Biochemistry”. 14-16.11.2019. Belgrade, Serbia (2019):118-118,
https://hdl.handle.net/21.15107/rcub_rimsi_2418 .