TY  - JOUR
AU  - Stojadinović, Gordana
AU  - Martać, Ljiljana
AU  - Podgorac, Jelena
AU  - Spasić, Slađana
AU  - Petković, Branka
AU  - Sekulic, Slobodan
AU  - Kesic, Srdjan
PY  - 2020
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1386
AB  - A detailed analysis of the anesthetic-induced modulation of intracerebellar electrical activity is an important step to understand the functional brain responses to anesthesia. We examined the electrical activity recorded from different cortical layers: molecular layer (ML), Purkinje cell layer (PCL), granular layer (GL) and the white matter (WM) in the vermian part of rat cerebellar lobule V during Nembutal anesthesia using spectral and fractal analysis. Spectral analysis revealed a difference in the mean relative power of delta (0.1-4.0 Hz) and theta (4.1-8.0 Hz) frequencies through the cerebellar layers. Compared to the ML, delta activity increased significantly in the GL, while theta activity decreased in the GL and the WM. Fractal analysis revealed that the mean value of Higuchi's fractal dimension (HFD) increased, starting from the ML to the WM. Theta activity exhibited a negative correlation with the HFD value in the ML. In contrast, the gamma activity showed a positive correlation with the HFD value in the ML and the GL. The combined use of spectral and fractal analyses revealed that Nembutal displays different effects on rat cerebellar electrical activity, which largely depends on the neurochemical and electrophysiological organization of the cerebellar layers.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - The effects of Nembutal on the intracerebellar EEG activity revealed by spectral and fractal analysis
EP  - 432
IS  - 3
SP  - 425
VL  - 72
DO  - 10.2298/ABS200524036S
ER  - 

@article{
author = "Stojadinović, Gordana and Martać, Ljiljana and Podgorac, Jelena and Spasić, Slađana and Petković, Branka and Sekulic, Slobodan and Kesic, Srdjan",
year = "2020",
abstract = "A detailed analysis of the anesthetic-induced modulation of intracerebellar electrical activity is an important step to understand the functional brain responses to anesthesia. We examined the electrical activity recorded from different cortical layers: molecular layer (ML), Purkinje cell layer (PCL), granular layer (GL) and the white matter (WM) in the vermian part of rat cerebellar lobule V during Nembutal anesthesia using spectral and fractal analysis. Spectral analysis revealed a difference in the mean relative power of delta (0.1-4.0 Hz) and theta (4.1-8.0 Hz) frequencies through the cerebellar layers. Compared to the ML, delta activity increased significantly in the GL, while theta activity decreased in the GL and the WM. Fractal analysis revealed that the mean value of Higuchi's fractal dimension (HFD) increased, starting from the ML to the WM. Theta activity exhibited a negative correlation with the HFD value in the ML. In contrast, the gamma activity showed a positive correlation with the HFD value in the ML and the GL. The combined use of spectral and fractal analyses revealed that Nembutal displays different effects on rat cerebellar electrical activity, which largely depends on the neurochemical and electrophysiological organization of the cerebellar layers.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "The effects of Nembutal on the intracerebellar EEG activity revealed by spectral and fractal analysis",
pages = "432-425",
number = "3",
volume = "72",
doi = "10.2298/ABS200524036S"
}

Stojadinović, G., Martać, L., Podgorac, J., Spasić, S., Petković, B., Sekulic, S.,& Kesic, S.. (2020). The effects of Nembutal on the intracerebellar EEG activity revealed by spectral and fractal analysis. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 72(3), 425-432.
https://doi.org/10.2298/ABS200524036S

Stojadinović G, Martać L, Podgorac J, Spasić S, Petković B, Sekulic S, Kesic S. The effects of Nembutal on the intracerebellar EEG activity revealed by spectral and fractal analysis. in Archives of Biological Sciences. 2020;72(3):425-432.
doi:10.2298/ABS200524036S .

Stojadinović, Gordana, Martać, Ljiljana, Podgorac, Jelena, Spasić, Slađana, Petković, Branka, Sekulic, Slobodan, Kesic, Srdjan, "The effects of Nembutal on the intracerebellar EEG activity revealed by spectral and fractal analysis" in Archives of Biological Sciences, 72, no. 3 (2020):425-432,
https://doi.org/10.2298/ABS200524036S . .

TY  - CONF
AU  - Stojadinović, Gordana
AU  - Yadollahpour, Ali
AU  - Kesić, Srđan Ž.
AU  - Spasić, Slađana
PY  - 2019-07-10
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2467
AB  - Aims: Electroencephalography (EEG) measures could be a potential markers for prediction of repetitive transcranial magnetic stimulation (rTMS) outcomes in depression. The aim of this study was to investigate the value of alpha asymmetric index (AAI) in predicting treatment response in two different protocols of rTMS in patients with intractable major depression. 
Methods: Patients with intractable major depression (n=34) were divided into two treatment groups underwent two different rTMS protocols. The first group  received ten sessions 20 Hz rTMS  The second group received 10 Hz rTMS . The EEGs were recorded in all subjects pre- and post-intervention using a 19-channel, 10-20 electrodes placement protocol. Hamilton depression rating scale-17 items (HDRS-17) was used to divide the patients into responders and non-responder. The AAI in prefrontal (Fp1-Fp2), frontal (F3-F4 and F7-F8), and temporal (T3-T4) regions were calculated and compared between pre- and post-intervention in each group and between the responder and non-responder groups.
Results: In the 20 Hz rTMS group responders, 6 patients responded to the treatment, whereas 10 Hz rTMS showed 8 responders. In the responders of 20 Hz rTMS, the AAI at Fp1-Fp2, F3-F4, and T3-T4significantly decreased after the intervention (P=0.011, P=0.042, and P=0.035). The responders of 10 Hz rTMS showed significant reduction in the AAI at Fp1-Fp2 and T3-T4 regions after intervention (P= 0.023 and P=0.044). 
Conclusions: It seems AAI at prefrontal and temporal region scould be used for prediction of treatment response, regardless of rTMS protocol.
C3  - FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.
T1  - Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2467
ER  - 

@conference{
author = "Stojadinović, Gordana and Yadollahpour, Ali and Kesić, Srđan Ž. and Spasić, Slađana",
year = "2019-07-10",
abstract = "Aims: Electroencephalography (EEG) measures could be a potential markers for prediction of repetitive transcranial magnetic stimulation (rTMS) outcomes in depression. The aim of this study was to investigate the value of alpha asymmetric index (AAI) in predicting treatment response in two different protocols of rTMS in patients with intractable major depression. 
Methods: Patients with intractable major depression (n=34) were divided into two treatment groups underwent two different rTMS protocols. The first group  received ten sessions 20 Hz rTMS  The second group received 10 Hz rTMS . The EEGs were recorded in all subjects pre- and post-intervention using a 19-channel, 10-20 electrodes placement protocol. Hamilton depression rating scale-17 items (HDRS-17) was used to divide the patients into responders and non-responder. The AAI in prefrontal (Fp1-Fp2), frontal (F3-F4 and F7-F8), and temporal (T3-T4) regions were calculated and compared between pre- and post-intervention in each group and between the responder and non-responder groups.
Results: In the 20 Hz rTMS group responders, 6 patients responded to the treatment, whereas 10 Hz rTMS showed 8 responders. In the responders of 20 Hz rTMS, the AAI at Fp1-Fp2, F3-F4, and T3-T4significantly decreased after the intervention (P=0.011, P=0.042, and P=0.035). The responders of 10 Hz rTMS showed significant reduction in the AAI at Fp1-Fp2 and T3-T4 regions after intervention (P= 0.023 and P=0.044). 
Conclusions: It seems AAI at prefrontal and temporal region scould be used for prediction of treatment response, regardless of rTMS protocol.",
journal = "FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.",
title = "Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2467"
}

Stojadinović, G., Yadollahpour, A., Kesić, S. Ž.,& Spasić, S.. (2019-07-10). Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609..
https://hdl.handle.net/21.15107/rcub_rimsi_2467

Stojadinović G, Yadollahpour A, Kesić SŽ, Spasić S. Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609.. 2019;.
https://hdl.handle.net/21.15107/rcub_rimsi_2467 .

Stojadinović, Gordana, Yadollahpour, Ali, Kesić, Srđan Ž., Spasić, Slađana, "Alpha asymmetry index of prefrontal and temporal regions predicts treatment response to repetitive transcranial magnetic stimulation" in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 609. (2019-07-10),
https://hdl.handle.net/21.15107/rcub_rimsi_2467 .

TY  - CONF
AU  - Kesić, Srđan Ž.
AU  - Yadollahpour, Ali
AU  - Riahi, F.
AU  - Naraghi, M.
AU  - Stojadinović, Gordana
AU  - Spasić, Slađana
PY  - 2019
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2383
AB  - Background and Aims: Neurofeedback treatment (NFT) may enhance attention performance in healthy individuals. This study investigated the effects of single session NFT on attention in healthy individuals performing a visual attention task. 
Methods: This was an open-label single-blinded trial conducted on 14 healthy university students (n=14; mean=23.35±0.58 years) of a major medical university in Iran. The subjects underwent a single session NFT while performing attentional network task (ANT). The NFT protocol was theta suppression/beta-1enhancement applied at Cz for 20 min. Before and immediately after NFT, EEG signals were recorded in subjects while performing ANT. EEGs were recorded using a 19 channel device and 10-20 placement protocol.
Results: The single session NFT increased the theta/beta-1 ratio in most of the electrode sites and the increase was statistically significant compared to the pre-intervention in the T6 site (p=0.011). The ratio decreased in just three sites of C3, Fz, and Cz, of them Fz showed a significant reduction (p=0.026). Contrary, the theta/alpha ratio decreased in most of the electrodes where the reductions were statistically significant in P3, P4, Cz, Pz (p<0.05), and C3 (p<0.01). The F7, F8, T3, and T4 showed no significant increased theta/alpha ratio. The central, temporal and occipital regions were involved in the NFT induced changes. Single NFT did not significantly change alerting, executive, or orienting networks of ANT.
Conclusions: Theta/beta-1 and theta/alpha ratios can be reliably used to assess NFT induced attention enhancement. However, single NFT did not induce clinical outcomes and repeated sessions seem necessary to modulate alerting, executive, or orienting networks of ANT.
C3  - FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369
T1  - Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention
IS  - 369
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2383
ER  - 

@conference{
author = "Kesić, Srđan Ž. and Yadollahpour, Ali and Riahi, F. and Naraghi, M. and Stojadinović, Gordana and Spasić, Slađana",
year = "2019",
abstract = "Background and Aims: Neurofeedback treatment (NFT) may enhance attention performance in healthy individuals. This study investigated the effects of single session NFT on attention in healthy individuals performing a visual attention task. 
Methods: This was an open-label single-blinded trial conducted on 14 healthy university students (n=14; mean=23.35±0.58 years) of a major medical university in Iran. The subjects underwent a single session NFT while performing attentional network task (ANT). The NFT protocol was theta suppression/beta-1enhancement applied at Cz for 20 min. Before and immediately after NFT, EEG signals were recorded in subjects while performing ANT. EEGs were recorded using a 19 channel device and 10-20 placement protocol.
Results: The single session NFT increased the theta/beta-1 ratio in most of the electrode sites and the increase was statistically significant compared to the pre-intervention in the T6 site (p=0.011). The ratio decreased in just three sites of C3, Fz, and Cz, of them Fz showed a significant reduction (p=0.026). Contrary, the theta/alpha ratio decreased in most of the electrodes where the reductions were statistically significant in P3, P4, Cz, Pz (p<0.05), and C3 (p<0.01). The F7, F8, T3, and T4 showed no significant increased theta/alpha ratio. The central, temporal and occipital regions were involved in the NFT induced changes. Single NFT did not significantly change alerting, executive, or orienting networks of ANT.
Conclusions: Theta/beta-1 and theta/alpha ratios can be reliably used to assess NFT induced attention enhancement. However, single NFT did not induce clinical outcomes and repeated sessions seem necessary to modulate alerting, executive, or orienting networks of ANT.",
journal = "FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369",
title = "Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention",
number = "369",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2383"
}

Kesić, S. Ž., Yadollahpour, A., Riahi, F., Naraghi, M., Stojadinović, G.,& Spasić, S.. (2019). Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369(369).
https://hdl.handle.net/21.15107/rcub_rimsi_2383

Kesić SŽ, Yadollahpour A, Riahi F, Naraghi M, Stojadinović G, Spasić S. Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention. in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369. 2019;(369).
https://hdl.handle.net/21.15107/rcub_rimsi_2383 .

Kesić, Srđan Ž., Yadollahpour, Ali, Riahi, F., Naraghi, M., Stojadinović, Gordana, Spasić, Slađana, "Single session neurofeedback treatment alters theta/beta-1 and theta/alpha ratios but not sufficient to induce clinical enhancement in attention" in FENS Regional Meeting, 10-13 July 2019, Belgrade-Serbia, Abstract p. 369, no. 369 (2019),
https://hdl.handle.net/21.15107/rcub_rimsi_2383 .

TY  - JOUR
AU  - Spasić, Slađana
AU  - Kesic, Srdjan
AU  - Stojadinović, Gordana
AU  - Petković, Branka
AU  - Todorović, Dajana
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/830
AB  - To study the influence of a static magnetic field (SMF, 2 mT) and extremely low frequency magnetic field (ELF MF, 50 Hz, 2 mT) on the neuronal population activity, the experiments were performed on adult longhorn beetles Morimus funereus (Coleoptera, Cerambycidae). Based on a wavelet analysis of the local field potentials (LFPs), our study showed for the first time that the effects of prolonged and repeated exposure to the ELF MF on the LFPs were irreversible within investigated time frame. The relative wavelet energy (RWE) of 4-8 Hz frequency band was significantly increased after sine ELF MF (SnMF)/square ELF MF (SqMF) in comparison to the control value. The RWE of slower oscillations (1-2 Hz) was significantly decreased after the repeated exposures to either SnMF or SqMF. The SqMF induced decreasing of the faster waves in the range of 64-128 Hz. However, we did not prove with presented methods that exposure to the SMF for 5 min produces any effects on the neuronal population activity. This study has proved the wavelet transform as a valuable tool for measuring the effects of SMF and ELF MF on the neuronal population activity in M. funereus antennal lobe.
PB  - Elsevier Science Inc, New York
T2  - Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
T1  - Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis
EP  - 35
SP  - 27
VL  - 181
DO  - 10.1016/j.cbpa.2014.11.018
ER  - 

@article{
author = "Spasić, Slađana and Kesic, Srdjan and Stojadinović, Gordana and Petković, Branka and Todorović, Dajana",
year = "2015",
abstract = "To study the influence of a static magnetic field (SMF, 2 mT) and extremely low frequency magnetic field (ELF MF, 50 Hz, 2 mT) on the neuronal population activity, the experiments were performed on adult longhorn beetles Morimus funereus (Coleoptera, Cerambycidae). Based on a wavelet analysis of the local field potentials (LFPs), our study showed for the first time that the effects of prolonged and repeated exposure to the ELF MF on the LFPs were irreversible within investigated time frame. The relative wavelet energy (RWE) of 4-8 Hz frequency band was significantly increased after sine ELF MF (SnMF)/square ELF MF (SqMF) in comparison to the control value. The RWE of slower oscillations (1-2 Hz) was significantly decreased after the repeated exposures to either SnMF or SqMF. The SqMF induced decreasing of the faster waves in the range of 64-128 Hz. However, we did not prove with presented methods that exposure to the SMF for 5 min produces any effects on the neuronal population activity. This study has proved the wavelet transform as a valuable tool for measuring the effects of SMF and ELF MF on the neuronal population activity in M. funereus antennal lobe.",
publisher = "Elsevier Science Inc, New York",
journal = "Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology",
title = "Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis",
pages = "35-27",
volume = "181",
doi = "10.1016/j.cbpa.2014.11.018"
}

Spasić, S., Kesic, S., Stojadinović, G., Petković, B.,& Todorović, D.. (2015). Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis. in Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
Elsevier Science Inc, New York., 181, 27-35.
https://doi.org/10.1016/j.cbpa.2014.11.018

Spasić S, Kesic S, Stojadinović G, Petković B, Todorović D. Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis. in Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology. 2015;181:27-35.
doi:10.1016/j.cbpa.2014.11.018 .

Spasić, Slađana, Kesic, Srdjan, Stojadinović, Gordana, Petković, Branka, Todorović, Dajana, "Effects of the static and ELF magnetic fields on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe revealed by wavelet analysis" in Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology, 181 (2015):27-35,
https://doi.org/10.1016/j.cbpa.2014.11.018 . .

TY  - CONF
AU  - Kesić, Srđan Ž.
AU  - Spasić, Slađana
AU  - Stojadinović, Gordana
AU  - Petković, Branka
AU  - Todorović, Dajana
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2388
PB  - Belgrade: Serbian Physiological Society
C3  - 3rd Congress of Physiological Sciences of Serbia With International Participation
T1  - Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2388
ER  - 

@conference{
author = "Kesić, Srđan Ž. and Spasić, Slađana and Stojadinović, Gordana and Petković, Branka and Todorović, Dajana",
year = "2014",
publisher = "Belgrade: Serbian Physiological Society",
journal = "3rd Congress of Physiological Sciences of Serbia With International Participation",
title = "Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2388"
}

Kesić, S. Ž., Spasić, S., Stojadinović, G., Petković, B.,& Todorović, D.. (2014). Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe. in 3rd Congress of Physiological Sciences of Serbia With International Participation
Belgrade: Serbian Physiological Society..
https://hdl.handle.net/21.15107/rcub_rimsi_2388

Kesić SŽ, Spasić S, Stojadinović G, Petković B, Todorović D. Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe. in 3rd Congress of Physiological Sciences of Serbia With International Participation. 2014;.
https://hdl.handle.net/21.15107/rcub_rimsi_2388 .

Kesić, Srđan Ž., Spasić, Slađana, Stojadinović, Gordana, Petković, Branka, Todorović, Dajana, "Relative wavelet energy as a measure of the magnetic fields effects on the neuronal population activity in Morimus funereus (Coleoptera, Cerambycidae) antennal lobe" in 3rd Congress of Physiological Sciences of Serbia With International Participation (2014),
https://hdl.handle.net/21.15107/rcub_rimsi_2388 .

TY  - JOUR
AU  - Spasić, Slađana
AU  - Culic, Milka
AU  - Grbic, Gordana
AU  - Martać, Ljiljana
AU  - Sekulic, Slobodan
AU  - Mutavdžić, Dragosav
PY  - 2008
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/253
AB  - The cerebellum, even when not directly damaged, is potentially interesting for understanding the adaptive responses to brain injury. Cerebellar electrocortical activity (ECoG) in rats was studied using spectral and fractal analysis after single and repeated unilateral injury of the parietal cortex. Local field potentials of cerebellar paravermal cortex were recorded before brain injury, in the acute phase (up to 2.5 hours) after a first injury of anesthetized rats, and then before and after second, third, and, in some cases, fourth injury. Relative gamma power (32.1-128.0 Hz) and fractal dimension of ECoGs were temporarily increased after the first injury. However, there was a permanent mild increase in gamma activity and a mild increase in the fractal dimension of cerebellar activity as a chronic change after repeated remote brain injury. There was a negative linear correlation between the normalized difference in fractal dimensions and normalized difference in gamma powers of cerebellar activity only in the case of repeated brain injury. This is the first study showing that correlation between the parameters of spectral and fractal analyses of cerebellar activity can discriminate between single and repeated brain injuries, and is, therefore, a promising approach for identifying specific pathophysiological states.
PB  - Springer, New York
T2  - Bulletin of Mathematical Biology
T1  - Spectral and fractal analysis of cerebellar activity after single and repeated brain injury
EP  - 1249
IS  - 4
SP  - 1235
VL  - 70
DO  - 10.1007/s11538-008-9306-5
ER  - 

@article{
author = "Spasić, Slađana and Culic, Milka and Grbic, Gordana and Martać, Ljiljana and Sekulic, Slobodan and Mutavdžić, Dragosav",
year = "2008",
abstract = "The cerebellum, even when not directly damaged, is potentially interesting for understanding the adaptive responses to brain injury. Cerebellar electrocortical activity (ECoG) in rats was studied using spectral and fractal analysis after single and repeated unilateral injury of the parietal cortex. Local field potentials of cerebellar paravermal cortex were recorded before brain injury, in the acute phase (up to 2.5 hours) after a first injury of anesthetized rats, and then before and after second, third, and, in some cases, fourth injury. Relative gamma power (32.1-128.0 Hz) and fractal dimension of ECoGs were temporarily increased after the first injury. However, there was a permanent mild increase in gamma activity and a mild increase in the fractal dimension of cerebellar activity as a chronic change after repeated remote brain injury. There was a negative linear correlation between the normalized difference in fractal dimensions and normalized difference in gamma powers of cerebellar activity only in the case of repeated brain injury. This is the first study showing that correlation between the parameters of spectral and fractal analyses of cerebellar activity can discriminate between single and repeated brain injuries, and is, therefore, a promising approach for identifying specific pathophysiological states.",
publisher = "Springer, New York",
journal = "Bulletin of Mathematical Biology",
title = "Spectral and fractal analysis of cerebellar activity after single and repeated brain injury",
pages = "1249-1235",
number = "4",
volume = "70",
doi = "10.1007/s11538-008-9306-5"
}

Spasić, S., Culic, M., Grbic, G., Martać, L., Sekulic, S.,& Mutavdžić, D.. (2008). Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. in Bulletin of Mathematical Biology
Springer, New York., 70(4), 1235-1249.
https://doi.org/10.1007/s11538-008-9306-5

Spasić S, Culic M, Grbic G, Martać L, Sekulic S, Mutavdžić D. Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. in Bulletin of Mathematical Biology. 2008;70(4):1235-1249.
doi:10.1007/s11538-008-9306-5 .

Spasić, Slađana, Culic, Milka, Grbic, Gordana, Martać, Ljiljana, Sekulic, Slobodan, Mutavdžić, Dragosav, "Spectral and fractal analysis of cerebellar activity after single and repeated brain injury" in Bulletin of Mathematical Biology, 70, no. 4 (2008):1235-1249,
https://doi.org/10.1007/s11538-008-9306-5 . .