TY  - JOUR
AU  - Grbic, G.
AU  - Culic, M.
AU  - Martać, Ljiljana
AU  - Soković, Marina
AU  - Spasić, Slađana
AU  - Doković, D.
PY  - 2008
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/239
AB  - The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intraperitoneal administration of camphor essential oil (450-675 mu l/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of ictal ECoG sequences were lower than those before camphor oil administration.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes
EP  - 553
IS  - 4
SP  - 547
VL  - 60
DO  - 10.2298/ABS0804547G
ER  - 

@article{
author = "Grbic, G. and Culic, M. and Martać, Ljiljana and Soković, Marina and Spasić, Slađana and Doković, D.",
year = "2008",
abstract = "The aim of our study was to investigate the effect of camphor essential oil on rat cerebral cortex activity by fractal analysis. Fractal dimension (FD) values of the parietal electrocortical activity were calculated before and after intraperitoneal administration of camphor essential oil (450-675 mu l/kg) in anesthetized rats. Camphor oil induced seizure-like activity with single and multiple spiking of high amplitudes in the parietal electrocorticogram and occasional clonic limb convulsions. The FD values of cortical activity after camphor oil administration increased on the average. Only FD values of ictal ECoG sequences were lower than those before camphor oil administration.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes",
pages = "553-547",
number = "4",
volume = "60",
doi = "10.2298/ABS0804547G"
}

Grbic, G., Culic, M., Martać, L., Soković, M., Spasić, S.,& Doković, D.. (2008). Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 60(4), 547-553.
https://doi.org/10.2298/ABS0804547G

Grbic G, Culic M, Martać L, Soković M, Spasić S, Doković D. Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes. in Archives of Biological Sciences. 2008;60(4):547-553.
doi:10.2298/ABS0804547G .

Grbic, G., Culic, M., Martać, Ljiljana, Soković, Marina, Spasić, Slađana, Doković, D., "Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes" in Archives of Biological Sciences, 60, no. 4 (2008):547-553,
https://doi.org/10.2298/ABS0804547G . .

TY  - JOUR
AU  - Grbic, G
AU  - Martać, Ljiljana
AU  - Culic, M
AU  - Todorović, V
AU  - Mitrović, O
AU  - Spasić, Slađana
PY  - 2005
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/118
PB  - Elsevier, Amsterdam
T2  - European Neuropsychopharmacology
T1  - Insulin-like growth factor immunoreactivity in rat cerebellum after acute and repeated unilateral brain injury
EP  - S245
SP  - S245
VL  - 15
DO  - 10.1016/S0924-977X(05)80481-X
ER  - 

@article{
author = "Grbic, G and Martać, Ljiljana and Culic, M and Todorović, V and Mitrović, O and Spasić, Slađana",
year = "2005",
publisher = "Elsevier, Amsterdam",
journal = "European Neuropsychopharmacology",
title = "Insulin-like growth factor immunoreactivity in rat cerebellum after acute and repeated unilateral brain injury",
pages = "S245-S245",
volume = "15",
doi = "10.1016/S0924-977X(05)80481-X"
}

Grbic, G., Martać, L., Culic, M., Todorović, V., Mitrović, O.,& Spasić, S.. (2005). Insulin-like growth factor immunoreactivity in rat cerebellum after acute and repeated unilateral brain injury. in European Neuropsychopharmacology
Elsevier, Amsterdam., 15, S245-S245.
https://doi.org/10.1016/S0924-977X(05)80481-X

Grbic G, Martać L, Culic M, Todorović V, Mitrović O, Spasić S. Insulin-like growth factor immunoreactivity in rat cerebellum after acute and repeated unilateral brain injury. in European Neuropsychopharmacology. 2005;15:S245-S245.
doi:10.1016/S0924-977X(05)80481-X .

Grbic, G, Martać, Ljiljana, Culic, M, Todorović, V, Mitrović, O, Spasić, Slađana, "Insulin-like growth factor immunoreactivity in rat cerebellum after acute and repeated unilateral brain injury" in European Neuropsychopharmacology, 15 (2005):S245-S245,
https://doi.org/10.1016/S0924-977X(05)80481-X . .

TY  - JOUR
AU  - Culic, M.
AU  - Blanusa, L.M.
AU  - Grbic, G.
AU  - Spasić, Slađana
AU  - Janković, B.
AU  - Kalauzi, Aleksandar
PY  - 2005
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/147
AB  - We investigated cerebellar electrocortical activity before and after unilateral brain injury in anesthetized rats. Spectral analysis of cerebellar activity was obtained by Fast Fourier Transformation. There was a dominance of delta frequency range, while the wide gamma range presented no more than 5% of the total mean power spectra of cerebellar activity before brain injury. A few minutes after brain injury and within the first 90 minutes, there was a decrease of total mean power spectra and a relative decrease of delta range power to about 30%, some increase of beta range, and an increase of gamma range to 20-25%. Relative increase of gamma range in the cerebellar mean power spectra was still present 120 min after the brain injury, while other changes started to diminish. We suggest that spectral changes within slow and fast (gamma) frequency ranges of cerebellar activity may be indicators of the brain state after acute injury.
PB  - Nencki Institute of Experimental Biology
T2  - Acta Neurobiologiae Experimentalis
T1  - Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats
EP  - 17
IS  - 1
SP  - 11
VL  - 65
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_147
ER  - 

@article{
author = "Culic, M. and Blanusa, L.M. and Grbic, G. and Spasić, Slađana and Janković, B. and Kalauzi, Aleksandar",
year = "2005",
abstract = "We investigated cerebellar electrocortical activity before and after unilateral brain injury in anesthetized rats. Spectral analysis of cerebellar activity was obtained by Fast Fourier Transformation. There was a dominance of delta frequency range, while the wide gamma range presented no more than 5% of the total mean power spectra of cerebellar activity before brain injury. A few minutes after brain injury and within the first 90 minutes, there was a decrease of total mean power spectra and a relative decrease of delta range power to about 30%, some increase of beta range, and an increase of gamma range to 20-25%. Relative increase of gamma range in the cerebellar mean power spectra was still present 120 min after the brain injury, while other changes started to diminish. We suggest that spectral changes within slow and fast (gamma) frequency ranges of cerebellar activity may be indicators of the brain state after acute injury.",
publisher = "Nencki Institute of Experimental Biology",
journal = "Acta Neurobiologiae Experimentalis",
title = "Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats",
pages = "17-11",
number = "1",
volume = "65",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_147"
}

Culic, M., Blanusa, L.M., Grbic, G., Spasić, S., Janković, B.,& Kalauzi, A.. (2005). Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats. in Acta Neurobiologiae Experimentalis
Nencki Institute of Experimental Biology., 65(1), 11-17.
https://hdl.handle.net/21.15107/rcub_rimsi_147

Culic M, Blanusa L, Grbic G, Spasić S, Janković B, Kalauzi A. Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats. in Acta Neurobiologiae Experimentalis. 2005;65(1):11-17.
https://hdl.handle.net/21.15107/rcub_rimsi_147 .

Culic, M., Blanusa, L.M., Grbic, G., Spasić, Slađana, Janković, B., Kalauzi, Aleksandar, "Spectral analysis of cerebellar activity after acute brain injury in anesthetized rats" in Acta Neurobiologiae Experimentalis, 65, no. 1 (2005):11-17,
https://hdl.handle.net/21.15107/rcub_rimsi_147 .

TY  - JOUR
AU  - Spasić, Slađana
AU  - Kalauzi, Aleksandar
AU  - Culic, M
AU  - Grbic, G
AU  - Martać, Ljiljana
PY  - 2005
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/136
AB  - We recorded electrocortical activity in anesthetized rats and constructed kmax new self-similar time series, applying Higuchi's algorithm. The aim of this study was to estimate value of the parameter k(max). in order to obtain fractal dimension values as an optimum measure of biosignal change. After our analysis, electrocortical activity recordings resulted in a family of curves f(k(max)). Three regions could be distinguished 2  lt = k(max).  lt  8, with a U-shape; 8  lt = k(max)  lt = 30, with a steeper quasilinear increase; and k(max) >= 30, with a smaller slope quasilinear increase. We suggest the optimum region for k(max): 8  lt  k(max)  lt  18, specifically k(max) = 8.
PB  - New York Acad Sciences, New York
T2  - Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus
T1  - Estimation of parameter k(max) in fractal analysis of rat brain activity
EP  - 429
SP  - 427
VL  - 1048
DO  - 10.1196/annals.1342.054
ER  - 

@article{
author = "Spasić, Slađana and Kalauzi, Aleksandar and Culic, M and Grbic, G and Martać, Ljiljana",
year = "2005",
abstract = "We recorded electrocortical activity in anesthetized rats and constructed kmax new self-similar time series, applying Higuchi's algorithm. The aim of this study was to estimate value of the parameter k(max). in order to obtain fractal dimension values as an optimum measure of biosignal change. After our analysis, electrocortical activity recordings resulted in a family of curves f(k(max)). Three regions could be distinguished 2  lt = k(max).  lt  8, with a U-shape; 8  lt = k(max)  lt = 30, with a steeper quasilinear increase; and k(max) >= 30, with a smaller slope quasilinear increase. We suggest the optimum region for k(max): 8  lt  k(max)  lt  18, specifically k(max) = 8.",
publisher = "New York Acad Sciences, New York",
journal = "Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus",
title = "Estimation of parameter k(max) in fractal analysis of rat brain activity",
pages = "429-427",
volume = "1048",
doi = "10.1196/annals.1342.054"
}

Spasić, S., Kalauzi, A., Culic, M., Grbic, G.,& Martać, L.. (2005). Estimation of parameter k(max) in fractal analysis of rat brain activity. in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus
New York Acad Sciences, New York., 1048, 427-429.
https://doi.org/10.1196/annals.1342.054

Spasić S, Kalauzi A, Culic M, Grbic G, Martać L. Estimation of parameter k(max) in fractal analysis of rat brain activity. in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus. 2005;1048:427-429.
doi:10.1196/annals.1342.054 .

Spasić, Slađana, Kalauzi, Aleksandar, Culic, M, Grbic, G, Martać, Ljiljana, "Estimation of parameter k(max) in fractal analysis of rat brain activity" in Biophysics From Molecules to Brain: in Memory of Radoslav K. Andjus, 1048 (2005):427-429,
https://doi.org/10.1196/annals.1342.054 . .

TY  - JOUR
AU  - Spasić, Slađana
AU  - Kalauzi, Aleksandar
AU  - Grbic, G
AU  - Martać, Ljiljana
AU  - Culic, M
PY  - 2005
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/128
AB  - With application of the Higuchi algorithm, fractal dimension (FD) values of the electrocortical activity of the rat parietal cerebral and paravermal cerebellar cortex were calculated, before and after unilateral discrete injury of the left parietal cortex. Immediately following the first acute injury, in a group of six rats, a reversible increase in mean FD was found at the left (ipsilateral side to the injury) cerebral cortex, from 1.38 to 1.59, and at the left cerebellar cortex from 1.51 to 1.73. In addition, an indication of plastic changes after repeated (third) injury was found as an irreversible increase in mean FD: 1.54 on the left and 1.48 on the right side of parietal cortex.
PB  - Springer Heidelberg, Heidelberg
T2  - Medical & Biological Engineering & Computing
T1  - Fractal analysis of rat brain activity after injury
EP  - 348
IS  - 3
SP  - 345
VL  - 43
DO  - 10.1007/BF02345811
ER  - 

@article{
author = "Spasić, Slađana and Kalauzi, Aleksandar and Grbic, G and Martać, Ljiljana and Culic, M",
year = "2005",
abstract = "With application of the Higuchi algorithm, fractal dimension (FD) values of the electrocortical activity of the rat parietal cerebral and paravermal cerebellar cortex were calculated, before and after unilateral discrete injury of the left parietal cortex. Immediately following the first acute injury, in a group of six rats, a reversible increase in mean FD was found at the left (ipsilateral side to the injury) cerebral cortex, from 1.38 to 1.59, and at the left cerebellar cortex from 1.51 to 1.73. In addition, an indication of plastic changes after repeated (third) injury was found as an irreversible increase in mean FD: 1.54 on the left and 1.48 on the right side of parietal cortex.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Medical & Biological Engineering & Computing",
title = "Fractal analysis of rat brain activity after injury",
pages = "348-345",
number = "3",
volume = "43",
doi = "10.1007/BF02345811"
}

Spasić, S., Kalauzi, A., Grbic, G., Martać, L.,& Culic, M.. (2005). Fractal analysis of rat brain activity after injury. in Medical & Biological Engineering & Computing
Springer Heidelberg, Heidelberg., 43(3), 345-348.
https://doi.org/10.1007/BF02345811

Spasić S, Kalauzi A, Grbic G, Martać L, Culic M. Fractal analysis of rat brain activity after injury. in Medical & Biological Engineering & Computing. 2005;43(3):345-348.
doi:10.1007/BF02345811 .

Spasić, Slađana, Kalauzi, Aleksandar, Grbic, G, Martać, Ljiljana, Culic, M, "Fractal analysis of rat brain activity after injury" in Medical & Biological Engineering & Computing, 43, no. 3 (2005):345-348,
https://doi.org/10.1007/BF02345811 . .

TY  - JOUR
AU  - Kalauzi, Aleksandar
AU  - Spasić, Slađana
AU  - Culic, M
AU  - Grbic, G
AU  - Martać, Ljiljana
PY  - 2005
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/123
AB  - We propose a new method for calculating fractal dimension (DF) of a signal y(t), based on coefficients m(y)((n)), mean absolute values of its nth order derivatives (consecutive finite differences for sampled signals). We found that logarithms of m(y)((n)), = 2, 3,..., n(max), exhibited linear dependence on n: log (m(y)((n))) = (slope)n + Y(int) with stable slopes and Y-intercepts proportional to signal DF values. Using a family of Weierstrass functions, we established a link between Y-intercepts and signal fractal dimension: DF = A(n(max))Y(int) + B(n(max)), and calculated parameters A(n(max)) and B(n(max)) for n(max) = 3,..., 7. Compared to Higuchi's algorithm, advantages of this method include greater speed and eliminating the need to choose value for k(max), since the smallest error was obtained with n(max) = 3.
PB  - World Scientific Publ Co Pte Ltd, Singapore
T2  - Fractals-Complex Geometry Patterns and Scaling in Nature and Society
T1  - Consecutive differences as a method of signal fractal analysis
EP  - 292
IS  - 4
SP  - 283
VL  - 13
DO  - 10.1142/S0218348X05002933
ER  - 

@article{
author = "Kalauzi, Aleksandar and Spasić, Slađana and Culic, M and Grbic, G and Martać, Ljiljana",
year = "2005",
abstract = "We propose a new method for calculating fractal dimension (DF) of a signal y(t), based on coefficients m(y)((n)), mean absolute values of its nth order derivatives (consecutive finite differences for sampled signals). We found that logarithms of m(y)((n)), = 2, 3,..., n(max), exhibited linear dependence on n: log (m(y)((n))) = (slope)n + Y(int) with stable slopes and Y-intercepts proportional to signal DF values. Using a family of Weierstrass functions, we established a link between Y-intercepts and signal fractal dimension: DF = A(n(max))Y(int) + B(n(max)), and calculated parameters A(n(max)) and B(n(max)) for n(max) = 3,..., 7. Compared to Higuchi's algorithm, advantages of this method include greater speed and eliminating the need to choose value for k(max), since the smallest error was obtained with n(max) = 3.",
publisher = "World Scientific Publ Co Pte Ltd, Singapore",
journal = "Fractals-Complex Geometry Patterns and Scaling in Nature and Society",
title = "Consecutive differences as a method of signal fractal analysis",
pages = "292-283",
number = "4",
volume = "13",
doi = "10.1142/S0218348X05002933"
}

Kalauzi, A., Spasić, S., Culic, M., Grbic, G.,& Martać, L.. (2005). Consecutive differences as a method of signal fractal analysis. in Fractals-Complex Geometry Patterns and Scaling in Nature and Society
World Scientific Publ Co Pte Ltd, Singapore., 13(4), 283-292.
https://doi.org/10.1142/S0218348X05002933

Kalauzi A, Spasić S, Culic M, Grbic G, Martać L. Consecutive differences as a method of signal fractal analysis. in Fractals-Complex Geometry Patterns and Scaling in Nature and Society. 2005;13(4):283-292.
doi:10.1142/S0218348X05002933 .

Kalauzi, Aleksandar, Spasić, Slađana, Culic, M, Grbic, G, Martać, Ljiljana, "Consecutive differences as a method of signal fractal analysis" in Fractals-Complex Geometry Patterns and Scaling in Nature and Society, 13, no. 4 (2005):283-292,
https://doi.org/10.1142/S0218348X05002933 . .

TY  - JOUR
AU  - Kalauzi, Aleksandar
AU  - Culic, M
AU  - Martać, Ljiljana
AU  - Grbic, G
AU  - Šaponjić, Jasna
AU  - Jovanović, A
AU  - Janković, B
AU  - Spasić, Slađana
PY  - 2003
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/85
AB  - The aim of this study was to reveal the nature and meaning of interspike background activity (RBA) recorded in Purkinje cell layer of rat cerebellum. We compared Fourier amplitude spectra of recorded, extracted and averaged simple spike(s) - SS and complex spike(s) - CS with the mean amplitude spectrum of the remaining interspike RBA. A much greater similarity of spectral characteristics was noticed between SS and RBA, than between CS and RBA. Then, we simulated background activity (SBA), by superimposing averaged SS with randomized amplitudes and time delays. There was a significant correlation (p lt 0.005) between linearly transformed simulated and recorded amplitude spectra. Mean amplitude spectra of SBA were positively correlated with the number of superimposed SS. We propose to use this fact as a qualitative indication about the direction of change in the mean activity of surrounding neuronal population.
PB  - Wiley, Hoboken
T2  - Neuroscience Research Communications
T1  - New view on cerebellar cortical background activity in rat: Simulation
EP  - 217
IS  - 3
SP  - 211
VL  - 32
DO  - 10.1002/nrc.10075
ER  - 

@article{
author = "Kalauzi, Aleksandar and Culic, M and Martać, Ljiljana and Grbic, G and Šaponjić, Jasna and Jovanović, A and Janković, B and Spasić, Slađana",
year = "2003",
abstract = "The aim of this study was to reveal the nature and meaning of interspike background activity (RBA) recorded in Purkinje cell layer of rat cerebellum. We compared Fourier amplitude spectra of recorded, extracted and averaged simple spike(s) - SS and complex spike(s) - CS with the mean amplitude spectrum of the remaining interspike RBA. A much greater similarity of spectral characteristics was noticed between SS and RBA, than between CS and RBA. Then, we simulated background activity (SBA), by superimposing averaged SS with randomized amplitudes and time delays. There was a significant correlation (p lt 0.005) between linearly transformed simulated and recorded amplitude spectra. Mean amplitude spectra of SBA were positively correlated with the number of superimposed SS. We propose to use this fact as a qualitative indication about the direction of change in the mean activity of surrounding neuronal population.",
publisher = "Wiley, Hoboken",
journal = "Neuroscience Research Communications",
title = "New view on cerebellar cortical background activity in rat: Simulation",
pages = "217-211",
number = "3",
volume = "32",
doi = "10.1002/nrc.10075"
}

Kalauzi, A., Culic, M., Martać, L., Grbic, G., Šaponjić, J., Jovanović, A., Janković, B.,& Spasić, S.. (2003). New view on cerebellar cortical background activity in rat: Simulation. in Neuroscience Research Communications
Wiley, Hoboken., 32(3), 211-217.
https://doi.org/10.1002/nrc.10075

Kalauzi A, Culic M, Martać L, Grbic G, Šaponjić J, Jovanović A, Janković B, Spasić S. New view on cerebellar cortical background activity in rat: Simulation. in Neuroscience Research Communications. 2003;32(3):211-217.
doi:10.1002/nrc.10075 .

Kalauzi, Aleksandar, Culic, M, Martać, Ljiljana, Grbic, G, Šaponjić, Jasna, Jovanović, A, Janković, B, Spasić, Slađana, "New view on cerebellar cortical background activity in rat: Simulation" in Neuroscience Research Communications, 32, no. 3 (2003):211-217,
https://doi.org/10.1002/nrc.10075 . .

TY  - JOUR
AU  - Culic, M
AU  - Grbic, G
AU  - Martać, Ljiljana
AU  - Todorović, V
AU  - Drndarević, N
AU  - Nikolic, JA
AU  - Kalauzi, Aleksandar
AU  - Spasić, Slađana
PY  - 2002
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/71
AB  - Vršena su istraživanja insulinu sličnog faktora rasta (IGF-I) na mišićno i koštano tkivo, ali je posvećena mala pažnja efektu na mozak u toku starenja. Mi smo ispitivali sadržaj IGF-I u moždanom tkivu pacova različite starosti. Nađeno je da su IGF-I koncentracije u kori malog mozga kao i velikog mozga mladih pacova (4-5 dana starih) više u poređenju sa sadržajima grupe tek-odraslih pacova starosti 2,5 meseca i grupe nešto starijih odraslih pacova (7,5-9 meseci starih). Međutim, smanjenje koncentracije IGF-I sadržaja samo u kori malog mozga nešto starijih pacova (7,5-9 meseci) bilo je značajno u odnosu na vrednosti u novorođenih (4-5 dana starih pacova). Naši rezultati ukazuju da IGF-I opada tokom života i moguće - selektivno u određenim moždanim regionima.
AB  - Although there has been extensive research on the effect of IGF-I on muscles and bone tissue, the effect on brain aging has received little attention. We investigated the IGF-I content in brains of differently aged rats. The IGF-I contents in cerebellar and cerebral cortex were found to be higher in immature rats (4-5 days old) compared to young adult (2.5 months old) and middle-aged (7.5-9 months old) rats. However, the decrease of mean IGF-I in middle-aged rats compared to immature animals was statistically significant only in the cerebellar codex. Our results indicate that IGF-I content decreases through the lifespan and maybe selectively in some brain regions.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Starosne promene u sadržaju insulin - sličnom faktora rasta i u mozgu pacova
T1  - Age-related changes in the content of insulin: Like growth factor-l in rat brain
EP  - 303
IS  - 5-6
SP  - 299
VL  - 52
DO  - 10.2298/AVB0206299C
ER  - 

@article{
author = "Culic, M and Grbic, G and Martać, Ljiljana and Todorović, V and Drndarević, N and Nikolic, JA and Kalauzi, Aleksandar and Spasić, Slađana",
year = "2002",
abstract = "Vršena su istraživanja insulinu sličnog faktora rasta (IGF-I) na mišićno i koštano tkivo, ali je posvećena mala pažnja efektu na mozak u toku starenja. Mi smo ispitivali sadržaj IGF-I u moždanom tkivu pacova različite starosti. Nađeno je da su IGF-I koncentracije u kori malog mozga kao i velikog mozga mladih pacova (4-5 dana starih) više u poređenju sa sadržajima grupe tek-odraslih pacova starosti 2,5 meseca i grupe nešto starijih odraslih pacova (7,5-9 meseci starih). Međutim, smanjenje koncentracije IGF-I sadržaja samo u kori malog mozga nešto starijih pacova (7,5-9 meseci) bilo je značajno u odnosu na vrednosti u novorođenih (4-5 dana starih pacova). Naši rezultati ukazuju da IGF-I opada tokom života i moguće - selektivno u određenim moždanim regionima., Although there has been extensive research on the effect of IGF-I on muscles and bone tissue, the effect on brain aging has received little attention. We investigated the IGF-I content in brains of differently aged rats. The IGF-I contents in cerebellar and cerebral cortex were found to be higher in immature rats (4-5 days old) compared to young adult (2.5 months old) and middle-aged (7.5-9 months old) rats. However, the decrease of mean IGF-I in middle-aged rats compared to immature animals was statistically significant only in the cerebellar codex. Our results indicate that IGF-I content decreases through the lifespan and maybe selectively in some brain regions.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Starosne promene u sadržaju insulin - sličnom faktora rasta i u mozgu pacova, Age-related changes in the content of insulin: Like growth factor-l in rat brain",
pages = "303-299",
number = "5-6",
volume = "52",
doi = "10.2298/AVB0206299C"
}

Culic, M., Grbic, G., Martać, L., Todorović, V., Drndarević, N., Nikolic, J., Kalauzi, A.,& Spasić, S.. (2002). Starosne promene u sadržaju insulin - sličnom faktora rasta i u mozgu pacova. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 52(5-6), 299-303.
https://doi.org/10.2298/AVB0206299C

Culic M, Grbic G, Martać L, Todorović V, Drndarević N, Nikolic J, Kalauzi A, Spasić S. Starosne promene u sadržaju insulin - sličnom faktora rasta i u mozgu pacova. in Acta Veterinaria-Beograd. 2002;52(5-6):299-303.
doi:10.2298/AVB0206299C .

Culic, M, Grbic, G, Martać, Ljiljana, Todorović, V, Drndarević, N, Nikolic, JA, Kalauzi, Aleksandar, Spasić, Slađana, "Starosne promene u sadržaju insulin - sličnom faktora rasta i u mozgu pacova" in Acta Veterinaria-Beograd, 52, no. 5-6 (2002):299-303,
https://doi.org/10.2298/AVB0206299C . .