TY  - JOUR
AU  - Spasić, Slađana
AU  - Culic, Milka
AU  - Grbic, Gordana
AU  - Martać, Ljiljana
AU  - Sekulic, Slobodan
AU  - Mutavdžić, Dragosav
PY  - 2008
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/253
AB  - The cerebellum, even when not directly damaged, is potentially interesting for understanding the adaptive responses to brain injury. Cerebellar electrocortical activity (ECoG) in rats was studied using spectral and fractal analysis after single and repeated unilateral injury of the parietal cortex. Local field potentials of cerebellar paravermal cortex were recorded before brain injury, in the acute phase (up to 2.5 hours) after a first injury of anesthetized rats, and then before and after second, third, and, in some cases, fourth injury. Relative gamma power (32.1-128.0 Hz) and fractal dimension of ECoGs were temporarily increased after the first injury. However, there was a permanent mild increase in gamma activity and a mild increase in the fractal dimension of cerebellar activity as a chronic change after repeated remote brain injury. There was a negative linear correlation between the normalized difference in fractal dimensions and normalized difference in gamma powers of cerebellar activity only in the case of repeated brain injury. This is the first study showing that correlation between the parameters of spectral and fractal analyses of cerebellar activity can discriminate between single and repeated brain injuries, and is, therefore, a promising approach for identifying specific pathophysiological states.
PB  - Springer, New York
T2  - Bulletin of Mathematical Biology
T1  - Spectral and fractal analysis of cerebellar activity after single and repeated brain injury
EP  - 1249
IS  - 4
SP  - 1235
VL  - 70
DO  - 10.1007/s11538-008-9306-5
ER  - 

@article{
author = "Spasić, Slađana and Culic, Milka and Grbic, Gordana and Martać, Ljiljana and Sekulic, Slobodan and Mutavdžić, Dragosav",
year = "2008",
abstract = "The cerebellum, even when not directly damaged, is potentially interesting for understanding the adaptive responses to brain injury. Cerebellar electrocortical activity (ECoG) in rats was studied using spectral and fractal analysis after single and repeated unilateral injury of the parietal cortex. Local field potentials of cerebellar paravermal cortex were recorded before brain injury, in the acute phase (up to 2.5 hours) after a first injury of anesthetized rats, and then before and after second, third, and, in some cases, fourth injury. Relative gamma power (32.1-128.0 Hz) and fractal dimension of ECoGs were temporarily increased after the first injury. However, there was a permanent mild increase in gamma activity and a mild increase in the fractal dimension of cerebellar activity as a chronic change after repeated remote brain injury. There was a negative linear correlation between the normalized difference in fractal dimensions and normalized difference in gamma powers of cerebellar activity only in the case of repeated brain injury. This is the first study showing that correlation between the parameters of spectral and fractal analyses of cerebellar activity can discriminate between single and repeated brain injuries, and is, therefore, a promising approach for identifying specific pathophysiological states.",
publisher = "Springer, New York",
journal = "Bulletin of Mathematical Biology",
title = "Spectral and fractal analysis of cerebellar activity after single and repeated brain injury",
pages = "1249-1235",
number = "4",
volume = "70",
doi = "10.1007/s11538-008-9306-5"
}

Spasić, S., Culic, M., Grbic, G., Martać, L., Sekulic, S.,& Mutavdžić, D.. (2008). Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. in Bulletin of Mathematical Biology
Springer, New York., 70(4), 1235-1249.
https://doi.org/10.1007/s11538-008-9306-5

Spasić S, Culic M, Grbic G, Martać L, Sekulic S, Mutavdžić D. Spectral and fractal analysis of cerebellar activity after single and repeated brain injury. in Bulletin of Mathematical Biology. 2008;70(4):1235-1249.
doi:10.1007/s11538-008-9306-5 .

Spasić, Slađana, Culic, Milka, Grbic, Gordana, Martać, Ljiljana, Sekulic, Slobodan, Mutavdžić, Dragosav, "Spectral and fractal analysis of cerebellar activity after single and repeated brain injury" in Bulletin of Mathematical Biology, 70, no. 4 (2008):1235-1249,
https://doi.org/10.1007/s11538-008-9306-5 . .