TY  - CONF
AU  - Milenković, Ivana
AU  - Algarra, Manuel
AU  - Joksimović, Kristina
AU  - Beškoski, Vladimir
AU  - Bandosz, Teresa J
AU  - Rodriguez-Castellon, Enrique
AU  - Radotić, Ksenija
PY  - 2022
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1853
AB  - Bacterial and fungal resistance is an increasingly severe problem. The high microbial resistance appears to be the consequence of the unconsidered use of antibiotics and antifungal drugs, and poor infection control in hospitals. Fighting microbial resistance by using new substances based on organic nanoparticles, carbon dots (CDs) may be a promising strategy in developing new therapeutic approaches. The metal-organic frameworks (MOFs), due to their unique features including high cargo loading, biodegradability, and ability of modification have become an attractive group of nanomaterials used in several fields including nanomedicine. In the current study, we synthesized N- and S-CDs@AgMOFs nanocomposites, new substances based on organic CDs nanoparticles inserted in MOFs structures. One Gram-positive (Bacillus subtilis), one Gram-negative (Escherichia coli) bacteria, and one fungi (Candida albicans) were treated with different concentrations (15.625, 31.25, 62.5, 125, 250, 500, 1000, and 2000 mg/L) of N- and S-CDs@AgMOFs nanocomposites during 48 h. The results showed the bactericidal effect of N- and S-CDs@AgMOFs on Bacillus subtillis and the antifungal effect on Candida albicans. The effect of S-CDs@AgMOFs was stronger on bacterial cells compared to the N-CDs@AgMOFs, while both agents affected fungi in equal concentrations, indicating different mechanisms in the two types of microorganisms. In Candida albicans, minimal inhibitory concentration (MIK) of both nanocomposites was 125 mg/L, while in Bacillus subtilis MIK of N-CDs@AgMOFs was 500 mg/L and for S-CDs@AgMOFs was 250 mg/L. It can be concluded that tested nanocomposites are safe for the environment because they are not toxic in the concentrations in which they can be found in the environment.
PB  - University in Banjaluka, Faculty of Technology
C3  - International conference ˮXIV Conference of Chemists, Technologists, and Environmentalists of Republic of Srpska“
T1  - Antibacterial and antifungal effect of S- and N-AgMOF-CDs nanocomposites
SP  - 157
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_1853
ER  - 

@conference{
author = "Milenković, Ivana and Algarra, Manuel and Joksimović, Kristina and Beškoski, Vladimir and Bandosz, Teresa J and Rodriguez-Castellon, Enrique and Radotić, Ksenija",
year = "2022",
abstract = "Bacterial and fungal resistance is an increasingly severe problem. The high microbial resistance appears to be the consequence of the unconsidered use of antibiotics and antifungal drugs, and poor infection control in hospitals. Fighting microbial resistance by using new substances based on organic nanoparticles, carbon dots (CDs) may be a promising strategy in developing new therapeutic approaches. The metal-organic frameworks (MOFs), due to their unique features including high cargo loading, biodegradability, and ability of modification have become an attractive group of nanomaterials used in several fields including nanomedicine. In the current study, we synthesized N- and S-CDs@AgMOFs nanocomposites, new substances based on organic CDs nanoparticles inserted in MOFs structures. One Gram-positive (Bacillus subtilis), one Gram-negative (Escherichia coli) bacteria, and one fungi (Candida albicans) were treated with different concentrations (15.625, 31.25, 62.5, 125, 250, 500, 1000, and 2000 mg/L) of N- and S-CDs@AgMOFs nanocomposites during 48 h. The results showed the bactericidal effect of N- and S-CDs@AgMOFs on Bacillus subtillis and the antifungal effect on Candida albicans. The effect of S-CDs@AgMOFs was stronger on bacterial cells compared to the N-CDs@AgMOFs, while both agents affected fungi in equal concentrations, indicating different mechanisms in the two types of microorganisms. In Candida albicans, minimal inhibitory concentration (MIK) of both nanocomposites was 125 mg/L, while in Bacillus subtilis MIK of N-CDs@AgMOFs was 500 mg/L and for S-CDs@AgMOFs was 250 mg/L. It can be concluded that tested nanocomposites are safe for the environment because they are not toxic in the concentrations in which they can be found in the environment.",
publisher = "University in Banjaluka, Faculty of Technology",
journal = "International conference ˮXIV Conference of Chemists, Technologists, and Environmentalists of Republic of Srpska“",
title = "Antibacterial and antifungal effect of S- and N-AgMOF-CDs nanocomposites",
pages = "157",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_1853"
}

Milenković, I., Algarra, M., Joksimović, K., Beškoski, V., Bandosz, T. J., Rodriguez-Castellon, E.,& Radotić, K.. (2022). Antibacterial and antifungal effect of S- and N-AgMOF-CDs nanocomposites. in International conference ˮXIV Conference of Chemists, Technologists, and Environmentalists of Republic of Srpska“
University in Banjaluka, Faculty of Technology., 157.
https://hdl.handle.net/21.15107/rcub_rimsi_1853

Milenković I, Algarra M, Joksimović K, Beškoski V, Bandosz TJ, Rodriguez-Castellon E, Radotić K. Antibacterial and antifungal effect of S- and N-AgMOF-CDs nanocomposites. in International conference ˮXIV Conference of Chemists, Technologists, and Environmentalists of Republic of Srpska“. 2022;:157.
https://hdl.handle.net/21.15107/rcub_rimsi_1853 .

Milenković, Ivana, Algarra, Manuel, Joksimović, Kristina, Beškoski, Vladimir, Bandosz, Teresa J, Rodriguez-Castellon, Enrique, Radotić, Ksenija, "Antibacterial and antifungal effect of S- and N-AgMOF-CDs nanocomposites" in International conference ˮXIV Conference of Chemists, Technologists, and Environmentalists of Republic of Srpska“ (2022):157,
https://hdl.handle.net/21.15107/rcub_rimsi_1853 .

TY  - CONF
AU  - Jovanović, Jelena
AU  - Ćirković, Jovana
AU  - Radojković, Aleksandar
AU  - Joksimović, Kristina
AU  - Omerović, Nejra
AU  - Branković, Goran
AU  - Branković, Zorica
PY  - 2022
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1740
AB  - The subject of this research was the development of biodegradable and eco-friendly material based on natural biopolymers from renewable sources, with the addition of active components for application in active food packaging. The main principle was the incorporation of the active components (lemongrass (Cymbopogon citratus L.) essential oil, ZnO nanoparticles, or Zn(CH3COO)2∙2H2O) with antimicrobial activity in the polymer matrix (chitosan, pectin, and gelatin), and their slow release during the time. All of the used components are listed as GRAS (Generally Recognized as Safe) by the U.S. Food and Drug Administration. Different formulations of emulsions and dispersions were processed for mutual comparison. The stability of chitosan and pectin emulsions was determined by using laser diffraction methods. Chitosan emulsions exhibited higher stability during 30 days of storage. The chitosan emulsions and dispersions exhibited a higher antibacterial effect in vitro against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Biopolymer coatings were formed by the spraying of emulsions on existing packaging. The effects of biopolymer coatings on the development of microorganisms on fresh raspberries (Rubus idaeus L.) were performed in vivo during eight days of raspberry storage at refrigerator temperature. The tested coatings extended the shelf life of stored raspberries from four to eight days. The synergistic effect between lemongrass essential oil and ZnO nanoparticles or Zn(CH3COO)2∙2H2O was observed both in vivo and in vitro.
PB  - University of Novi Sad, Faculty of Technology Novi Sad
C3  - 2nd International Conference on Advanced Production and Processing (ICAPP), Novi Sad, Serbia
T1  - CHITOSAN- AND PECTIN-BASED COATINGS WITH
INCORPORATED ACTIVE COMPONENTS FOR APPLICATION IN
ACTIVE FOOD PACKAGING
SP  - 115
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_1740
ER  - 

@conference{
author = "Jovanović, Jelena and Ćirković, Jovana and Radojković, Aleksandar and Joksimović, Kristina and Omerović, Nejra and Branković, Goran and Branković, Zorica",
year = "2022",
abstract = "The subject of this research was the development of biodegradable and eco-friendly material based on natural biopolymers from renewable sources, with the addition of active components for application in active food packaging. The main principle was the incorporation of the active components (lemongrass (Cymbopogon citratus L.) essential oil, ZnO nanoparticles, or Zn(CH3COO)2∙2H2O) with antimicrobial activity in the polymer matrix (chitosan, pectin, and gelatin), and their slow release during the time. All of the used components are listed as GRAS (Generally Recognized as Safe) by the U.S. Food and Drug Administration. Different formulations of emulsions and dispersions were processed for mutual comparison. The stability of chitosan and pectin emulsions was determined by using laser diffraction methods. Chitosan emulsions exhibited higher stability during 30 days of storage. The chitosan emulsions and dispersions exhibited a higher antibacterial effect in vitro against Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Biopolymer coatings were formed by the spraying of emulsions on existing packaging. The effects of biopolymer coatings on the development of microorganisms on fresh raspberries (Rubus idaeus L.) were performed in vivo during eight days of raspberry storage at refrigerator temperature. The tested coatings extended the shelf life of stored raspberries from four to eight days. The synergistic effect between lemongrass essential oil and ZnO nanoparticles or Zn(CH3COO)2∙2H2O was observed both in vivo and in vitro.",
publisher = "University of Novi Sad, Faculty of Technology Novi Sad",
journal = "2nd International Conference on Advanced Production and Processing (ICAPP), Novi Sad, Serbia",
title = "CHITOSAN- AND PECTIN-BASED COATINGS WITH
INCORPORATED ACTIVE COMPONENTS FOR APPLICATION IN
ACTIVE FOOD PACKAGING",
pages = "115",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_1740"
}

Jovanović, J., Ćirković, J., Radojković, A., Joksimović, K., Omerović, N., Branković, G.,& Branković, Z.. (2022). CHITOSAN- AND PECTIN-BASED COATINGS WITH
INCORPORATED ACTIVE COMPONENTS FOR APPLICATION IN
ACTIVE FOOD PACKAGING. in 2nd International Conference on Advanced Production and Processing (ICAPP), Novi Sad, Serbia
University of Novi Sad, Faculty of Technology Novi Sad., 115.
https://hdl.handle.net/21.15107/rcub_rimsi_1740

Jovanović J, Ćirković J, Radojković A, Joksimović K, Omerović N, Branković G, Branković Z. CHITOSAN- AND PECTIN-BASED COATINGS WITH
INCORPORATED ACTIVE COMPONENTS FOR APPLICATION IN
ACTIVE FOOD PACKAGING. in 2nd International Conference on Advanced Production and Processing (ICAPP), Novi Sad, Serbia. 2022;:115.
https://hdl.handle.net/21.15107/rcub_rimsi_1740 .

Jovanović, Jelena, Ćirković, Jovana, Radojković, Aleksandar, Joksimović, Kristina, Omerović, Nejra, Branković, Goran, Branković, Zorica, "CHITOSAN- AND PECTIN-BASED COATINGS WITH
INCORPORATED ACTIVE COMPONENTS FOR APPLICATION IN
ACTIVE FOOD PACKAGING" in 2nd International Conference on Advanced Production and Processing (ICAPP), Novi Sad, Serbia (2022):115,
https://hdl.handle.net/21.15107/rcub_rimsi_1740 .

TY  - JOUR
AU  - Jovanović, Jelena
AU  - Ćirković, Jovana
AU  - Radojković, Aleksandar
AU  - Mutavdžić, Dragosav
AU  - Tanasijević, Gordana
AU  - Joksimović, Kristina
AU  - Bakic, Gordana
AU  - Branković, Goran
AU  - Branković, Zorica
PY  - 2021
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1422
AB  - This investigation was aimed to develop films and coatings based on natural biopolymers and active components, with physicochemical and functional properties for application in antimicrobial packaging. Biopolymer films were obtained from emulsions and dispersions by casting method. Coatings were formed by the application of emulsions on existing packaging. Synthesis of emulsions and dispersions were performed by combining biopolymers (chitosan-gelatin, pectin-gelatin) with lemongrass essential oil (LEO), Zn(CH3COO)2.2H2O, or ZnO, as active components. Fourier transform infrared (FTIR) spectra of the films showed that the addition of glycerol contributed to the forming of strong hydrogen bonds between glycerol and chitosan-gelatin or pectin-gelatin composites, facilitating the process of polymer branching, which is substantial for encapsulation. Thermal analyses revealed two characteristic processes occurring at 110 degrees C (water evaporation) and within 215-235 degrees C (degradation of polysaccharide and glycerol). Major weight losses were observed at 290 degrees C (chitosan-gelatin films) and 215 degrees C (pectin-gelatin films). The chitosan-gelatin films exhibited a lower degree of solubility (31-21%), and better mechanical properties comparing with the pectin-gelatin films. The chitosan-gelatin emulsions and dispersions exhibited a higher antibacterial effect in vitro against E. coli, B. subtilis, and S. aureus. In the case of the pectin-gelatin emulsions, the impact of LEO on the antibacterial activity was evident. The effects of biopolymer coatings on the development of microorganisms on fresh raspberries (Rubus idaeus L.) were performed in vivo during eight days of raspberry storage at refrigerator temperature. The tested coatings extended the shelf life of stored raspberries from four to eight days. The synergistic effect between LEO and ZnO or Zn-Ac was observed both in vivo and in vitro.
PB  - Elsevier Science Sa, Lausanne
T2  - Progress in Organic Coatings
T1  - Chitosan and pectin-based films and coatings with active components for application in antimicrobial food packaging
VL  - 158
DO  - 10.1016/j.porgcoat.2021.106349
ER  - 

@article{
author = "Jovanović, Jelena and Ćirković, Jovana and Radojković, Aleksandar and Mutavdžić, Dragosav and Tanasijević, Gordana and Joksimović, Kristina and Bakic, Gordana and Branković, Goran and Branković, Zorica",
year = "2021",
abstract = "This investigation was aimed to develop films and coatings based on natural biopolymers and active components, with physicochemical and functional properties for application in antimicrobial packaging. Biopolymer films were obtained from emulsions and dispersions by casting method. Coatings were formed by the application of emulsions on existing packaging. Synthesis of emulsions and dispersions were performed by combining biopolymers (chitosan-gelatin, pectin-gelatin) with lemongrass essential oil (LEO), Zn(CH3COO)2.2H2O, or ZnO, as active components. Fourier transform infrared (FTIR) spectra of the films showed that the addition of glycerol contributed to the forming of strong hydrogen bonds between glycerol and chitosan-gelatin or pectin-gelatin composites, facilitating the process of polymer branching, which is substantial for encapsulation. Thermal analyses revealed two characteristic processes occurring at 110 degrees C (water evaporation) and within 215-235 degrees C (degradation of polysaccharide and glycerol). Major weight losses were observed at 290 degrees C (chitosan-gelatin films) and 215 degrees C (pectin-gelatin films). The chitosan-gelatin films exhibited a lower degree of solubility (31-21%), and better mechanical properties comparing with the pectin-gelatin films. The chitosan-gelatin emulsions and dispersions exhibited a higher antibacterial effect in vitro against E. coli, B. subtilis, and S. aureus. In the case of the pectin-gelatin emulsions, the impact of LEO on the antibacterial activity was evident. The effects of biopolymer coatings on the development of microorganisms on fresh raspberries (Rubus idaeus L.) were performed in vivo during eight days of raspberry storage at refrigerator temperature. The tested coatings extended the shelf life of stored raspberries from four to eight days. The synergistic effect between LEO and ZnO or Zn-Ac was observed both in vivo and in vitro.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Progress in Organic Coatings",
title = "Chitosan and pectin-based films and coatings with active components for application in antimicrobial food packaging",
volume = "158",
doi = "10.1016/j.porgcoat.2021.106349"
}

Jovanović, J., Ćirković, J., Radojković, A., Mutavdžić, D., Tanasijević, G., Joksimović, K., Bakic, G., Branković, G.,& Branković, Z.. (2021). Chitosan and pectin-based films and coatings with active components for application in antimicrobial food packaging. in Progress in Organic Coatings
Elsevier Science Sa, Lausanne., 158.
https://doi.org/10.1016/j.porgcoat.2021.106349

Jovanović J, Ćirković J, Radojković A, Mutavdžić D, Tanasijević G, Joksimović K, Bakic G, Branković G, Branković Z. Chitosan and pectin-based films and coatings with active components for application in antimicrobial food packaging. in Progress in Organic Coatings. 2021;158.
doi:10.1016/j.porgcoat.2021.106349 .

Jovanović, Jelena, Ćirković, Jovana, Radojković, Aleksandar, Mutavdžić, Dragosav, Tanasijević, Gordana, Joksimović, Kristina, Bakic, Gordana, Branković, Goran, Branković, Zorica, "Chitosan and pectin-based films and coatings with active components for application in antimicrobial food packaging" in Progress in Organic Coatings, 158 (2021),
https://doi.org/10.1016/j.porgcoat.2021.106349 . .