TY  - JOUR
AU  - Kalauzi, Aleksandar
AU  - Spasić, Slađana
AU  - Petrović, Jelena
AU  - Ciric, Jelena
AU  - Šaponjić, Jasna
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/550
AB  - This study was aimed to explore the sleep/wake states related cortico-pontine theta carrier frequency phase shift following a systemically induced chemical axotomy of the monoaminergic afferents within a brain of the freely moving rats. Our experiments were performed in 14 adult, male Sprague Dawley rats, chronically implanted for sleep recording. We recorded sleep during baseline condition, following sham injection (saline i.p. 1 ml/kg), and every week for 5 weeks following injection of the systemic neurotoxins (DSP-4 or PCA; 1 ml/kg, i.p.) for chemical axotomy of the locus coeruleus (LC) and dorsal raphe (DR) axon terminals. After sleep/wake states identification, FFT analysis was performed on 5 s epochs. Theta carrier frequency phase shift (Delta Phi) was calculated for each epoch by averaging theta Fourier component phase shifts, and the Delta Phi values were plotted for each rat in control condition and 28 days following the monoaminergic lesions, as a time for permanently established DR or LC chemical axotomy. Calculated group averages have shown that Delta Phi increased between pons and cortex significantly in all sleep/wake states (Wake, NREM and REM) following the monoaminergic lesions, with respect to controls. Monoaminergic lesions established the pontine leading role in the brain theta oscillations during all sleep/wake states.
PB  - General Physiol And Biophysics, Bratislava
T2  - General Physiology and Biophysics
T1  - Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat
EP  - 171
IS  - 2
SP  - 163
VL  - 31
DO  - 10.4149/gpb_2012_018
ER  - 

@article{
author = "Kalauzi, Aleksandar and Spasić, Slađana and Petrović, Jelena and Ciric, Jelena and Šaponjić, Jasna",
year = "2012",
abstract = "This study was aimed to explore the sleep/wake states related cortico-pontine theta carrier frequency phase shift following a systemically induced chemical axotomy of the monoaminergic afferents within a brain of the freely moving rats. Our experiments were performed in 14 adult, male Sprague Dawley rats, chronically implanted for sleep recording. We recorded sleep during baseline condition, following sham injection (saline i.p. 1 ml/kg), and every week for 5 weeks following injection of the systemic neurotoxins (DSP-4 or PCA; 1 ml/kg, i.p.) for chemical axotomy of the locus coeruleus (LC) and dorsal raphe (DR) axon terminals. After sleep/wake states identification, FFT analysis was performed on 5 s epochs. Theta carrier frequency phase shift (Delta Phi) was calculated for each epoch by averaging theta Fourier component phase shifts, and the Delta Phi values were plotted for each rat in control condition and 28 days following the monoaminergic lesions, as a time for permanently established DR or LC chemical axotomy. Calculated group averages have shown that Delta Phi increased between pons and cortex significantly in all sleep/wake states (Wake, NREM and REM) following the monoaminergic lesions, with respect to controls. Monoaminergic lesions established the pontine leading role in the brain theta oscillations during all sleep/wake states.",
publisher = "General Physiol And Biophysics, Bratislava",
journal = "General Physiology and Biophysics",
title = "Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat",
pages = "171-163",
number = "2",
volume = "31",
doi = "10.4149/gpb_2012_018"
}

Kalauzi, A., Spasić, S., Petrović, J., Ciric, J.,& Šaponjić, J.. (2012). Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat. in General Physiology and Biophysics
General Physiol And Biophysics, Bratislava., 31(2), 163-171.
https://doi.org/10.4149/gpb_2012_018

Kalauzi A, Spasić S, Petrović J, Ciric J, Šaponjić J. Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat. in General Physiology and Biophysics. 2012;31(2):163-171.
doi:10.4149/gpb_2012_018 .

Kalauzi, Aleksandar, Spasić, Slađana, Petrović, Jelena, Ciric, Jelena, Šaponjić, Jasna, "Cortico-pontine theta carrier frequency phase shift across sleep/wake states following monoaminergic lesion in rat" in General Physiology and Biophysics, 31, no. 2 (2012):163-171,
https://doi.org/10.4149/gpb_2012_018 . .