Savić, Aleksandar G

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Authority KeyName Variants
12478c68-b67e-4a4a-a6f8-0fc6ae990843
  • Savić, Aleksandar G (22)
  • Savić, Aleksandar (5)
Projects
Study of structure-function relationships in the plant cell wall and modifications of the wall structure by enzyme engineering Biomarkers in neurodegenerative and malignant processes
The membranes as sites of interaction between the intracellular and apoplastic environments: studies of the bioenergetics and signaling using biophysical and biochemical techniques. Natural products of wild, cultivated and edible plants: structure and bioactivity determination
Fishes as water quality indicators in open waters of Serbia Pharmacodynamic and pharmacogenomic research of new drugs in the treatment of solid tumors
Characterization and application of fungal metabolites and assessment of new biofungicides potential European CommissionEuropean CommissionEuropean Commission Joint Research Centre
Synthesis, processing and characterization of nanostructured materials for application in the field of energy, mechanical engineering, environmental protection and biomedicine Italian Ministry of Foreign AffairsMinistry of Foreign Affairs and International Cooperation (Italy)
project Algain [EE2.3.30.0059] Algatech Plus [MSMT LO1416]
bilateral project "Advanced image analysis on micron scale in biology and medicine" of the Republic of Serbia bilateral project "Structural anisotropy of plant cell walls of various origin and their constituent polymers, using differential-polarized laser scanning microscopy (DP-LSM)", of the Republic of Serbia
Ciencia 2007 program (FCT-Portugal) Department of Agricultural and Food Sciences, Alma Mater Studiorum, University of Bologna, Italy
Erasmus Mundus fellowship under EMECW FCTPortuguese Foundation for Science and TechnologyEuropean Commission [E-15/11]
Hungarian Science Foundation (OTKA)Orszagos Tudomanyos Kutatasi Alapprogramok (OTKA) [K77840] II-20080239]
Molecular mechanisms of redox signalling in homeostasis: adaptation and pathology The effects of magnetic fields and other environmental stressors on the physiological responses and behavior of different species
Micromorphological, phytochemical and molecular investigations of plants - systematic, ecological and applicative aspects The role of autophagy in regulation of cancer cell death
Identification of predictive molecular markers for cancer progression, response to therapy and disease outcome Modulation of antioxidative metabolism in plants for improvement of plant abiotic stress tolerance and identification of new biomarkers for application in remediation and monitoring of degraded biotopes
Functional, Functionalized and Advanced Nanomaterials Multiscale structuring of polymer nanocomposites and functional materials based on different precursors
institutional projects Algatech [CZ.1.05/2.1.00/03.0110] MCINNEuropean Commission [AIB201OPT-00299]

Author's Bibliography

Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending

Nedzved, Aleksander; Mitrović, Aleksandra Lj.; Savić, Aleksandar G; Mutavdžić, Dragosav; Simonović Radosavljević, Jasna; Bogdanović Pristov, Jelena; Steinbach, Gabor; Garab, Gyozo; Starovoytov, Valery; Radotić, Ksenija

(Springer Heidelberg, Heidelberg, 2018)

TY  - JOUR
AU  - Nedzved, Aleksander
AU  - Mitrović, Aleksandra Lj.
AU  - Savić, Aleksandar G
AU  - Mutavdžić, Dragosav
AU  - Simonović Radosavljević, Jasna
AU  - Bogdanović Pristov, Jelena
AU  - Steinbach, Gabor
AU  - Garab, Gyozo
AU  - Starovoytov, Valery
AU  - Radotić, Ksenija
PY  - 2018
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/1116
AB  - Measurements of various anatomical characteristics of wood cells are of great importance in research of wood structure, either for the evaluation of environmental influences or for estimation of wood quality. We present and test an automatic image processing morphometric method for the analysis of tracheid double wall thickness. A new algorithm of image analysis was developed. It uses morphological processing of structural elements with the different orientations from distance maps to analyze tracheid double wall thickness distribution separately for radial walls, tangential walls, and cell corners. For testing the performance of the method, we used confocal laser scanning microscopy images of stem cross-sections of juvenile Picea omorika trees exposed to long-term static bending. As a response to mechanical stress, conifers form compression wood (CW), which occurs in a range of gradations from near normal wood (NW) to severe CW. However, visual detection of compression wood severity, more precisely the determination of mild CW, is difficult. One of the anatomic features that characterize CW is increased wall thickness. After testing proposed automatic image processing morphometric method for the analysis of tracheid double wall thickness separately for radial walls, tangential walls and cell corners, combined with statistical analysis, we could suggest it as a tool for estimation of compression wood severity, or for estimation and gradation of changes in tracheid cell wall thickness as a response to environmental influences during growth and developmental process.
PB  - Springer Heidelberg, Heidelberg
T2  - Trees-Structure and Function
T1  - Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending
EP  - 1356
IS  - 5
SP  - 1347
VL  - 32
DO  - 10.1007/s00468-018-1716-x
ER  - 
@article{
author = "Nedzved, Aleksander and Mitrović, Aleksandra Lj. and Savić, Aleksandar G and Mutavdžić, Dragosav and Simonović Radosavljević, Jasna and Bogdanović Pristov, Jelena and Steinbach, Gabor and Garab, Gyozo and Starovoytov, Valery and Radotić, Ksenija",
year = "2018",
abstract = "Measurements of various anatomical characteristics of wood cells are of great importance in research of wood structure, either for the evaluation of environmental influences or for estimation of wood quality. We present and test an automatic image processing morphometric method for the analysis of tracheid double wall thickness. A new algorithm of image analysis was developed. It uses morphological processing of structural elements with the different orientations from distance maps to analyze tracheid double wall thickness distribution separately for radial walls, tangential walls, and cell corners. For testing the performance of the method, we used confocal laser scanning microscopy images of stem cross-sections of juvenile Picea omorika trees exposed to long-term static bending. As a response to mechanical stress, conifers form compression wood (CW), which occurs in a range of gradations from near normal wood (NW) to severe CW. However, visual detection of compression wood severity, more precisely the determination of mild CW, is difficult. One of the anatomic features that characterize CW is increased wall thickness. After testing proposed automatic image processing morphometric method for the analysis of tracheid double wall thickness separately for radial walls, tangential walls and cell corners, combined with statistical analysis, we could suggest it as a tool for estimation of compression wood severity, or for estimation and gradation of changes in tracheid cell wall thickness as a response to environmental influences during growth and developmental process.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Trees-Structure and Function",
title = "Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending",
pages = "1356-1347",
number = "5",
volume = "32",
doi = "10.1007/s00468-018-1716-x"
}
Nedzved, A., Mitrović, A. Lj., Savić, A. G., Mutavdžić, D., Simonović Radosavljević, J., Bogdanović Pristov, J., Steinbach, G., Garab, G., Starovoytov, V.,& Radotić, K.. (2018). Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending. in Trees-Structure and Function
Springer Heidelberg, Heidelberg., 32(5), 1347-1356.
https://doi.org/10.1007/s00468-018-1716-x
Nedzved A, Mitrović AL, Savić AG, Mutavdžić D, Simonović Radosavljević J, Bogdanović Pristov J, Steinbach G, Garab G, Starovoytov V, Radotić K. Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending. in Trees-Structure and Function. 2018;32(5):1347-1356.
doi:10.1007/s00468-018-1716-x .
Nedzved, Aleksander, Mitrović, Aleksandra Lj., Savić, Aleksandar G, Mutavdžić, Dragosav, Simonović Radosavljević, Jasna, Bogdanović Pristov, Jelena, Steinbach, Gabor, Garab, Gyozo, Starovoytov, Valery, Radotić, Ksenija, "Automatic image processing morphometric method for the analysis of tracheid double wall thickness tested on juvenile Picea omorika trees exposed to static bending" in Trees-Structure and Function, 32, no. 5 (2018):1347-1356,
https://doi.org/10.1007/s00468-018-1716-x . .
4
5

Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity

Savić, Aleksandar; Mitrović, Aleksandra Lj.; Donaldson, Loyd; Simonović Radosavljević, Jasna; Bogdanović Pristov, Jelena; Steinbach, Gabor; Garab, Gozyo; Radotić, Ksenija

(Faculty of Sciences and Mathematics (Niš). Depattment of Biology and Ecology, 2016)

TY  - CONF
AU  - Savić, Aleksandar
AU  - Mitrović, Aleksandra Lj.
AU  - Donaldson, Loyd
AU  - Simonović Radosavljević, Jasna
AU  - Bogdanović Pristov, Jelena
AU  - Steinbach, Gabor
AU  - Garab, Gozyo
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2969
PB  - Faculty of Sciences and Mathematics (Niš). Depattment of Biology and Ecology
PB  - Biological Society "Dr Sava Petrović" Niš
C3  - 12th Symposium on the Flora of Southeastern Serbia and Neighboring Regions
T1  - Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity
SP  - 78
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2969
ER  - 
@conference{
author = "Savić, Aleksandar and Mitrović, Aleksandra Lj. and Donaldson, Loyd and Simonović Radosavljević, Jasna and Bogdanović Pristov, Jelena and Steinbach, Gabor and Garab, Gozyo and Radotić, Ksenija",
year = "2016",
publisher = "Faculty of Sciences and Mathematics (Niš). Depattment of Biology and Ecology, Biological Society "Dr Sava Petrović" Niš",
journal = "12th Symposium on the Flora of Southeastern Serbia and Neighboring Regions",
title = "Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity",
pages = "78",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2969"
}
Savić, A., Mitrović, A. Lj., Donaldson, L., Simonović Radosavljević, J., Bogdanović Pristov, J., Steinbach, G., Garab, G.,& Radotić, K.. (2016). Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity. in 12th Symposium on the Flora of Southeastern Serbia and Neighboring Regions
Faculty of Sciences and Mathematics (Niš). Depattment of Biology and Ecology., 78.
https://hdl.handle.net/21.15107/rcub_rimsi_2969
Savić A, Mitrović AL, Donaldson L, Simonović Radosavljević J, Bogdanović Pristov J, Steinbach G, Garab G, Radotić K. Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity. in 12th Symposium on the Flora of Southeastern Serbia and Neighboring Regions. 2016;:78.
https://hdl.handle.net/21.15107/rcub_rimsi_2969 .
Savić, Aleksandar, Mitrović, Aleksandra Lj., Donaldson, Loyd, Simonović Radosavljević, Jasna, Bogdanović Pristov, Jelena, Steinbach, Gabor, Garab, Gozyo, Radotić, Ksenija, "Cellulose fibril order in radial wood cell walls of juvenile Serbian spruce: estimation of compression wood severity" in 12th Symposium on the Flora of Southeastern Serbia and Neighboring Regions (2016):78,
https://hdl.handle.net/21.15107/rcub_rimsi_2969 .

Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity

Savić, Aleksandar G; Mitrović, Aleksandra Lj.; Donaldson, Lloyd; Simonović Radosavljević, Jasna; Bogdanović Pristov, Jelena; Steinbach, Gabor; Garab, Gyozo; Radotić, Ksenija

(Cambridge Univ Press, New York, 2016)

TY  - JOUR
AU  - Savić, Aleksandar G
AU  - Mitrović, Aleksandra Lj.
AU  - Donaldson, Lloyd
AU  - Simonović Radosavljević, Jasna
AU  - Bogdanović Pristov, Jelena
AU  - Steinbach, Gabor
AU  - Garab, Gyozo
AU  - Radotić, Ksenija
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/989
AB  - Fluorescence-detected linear dichroism (FDLD) microscopy provides observation of structural order in a microscopic sample and its expression in numerical terms, enabling both quantitative and qualitative comparison among different samples. We applied FDLD microscopy to compare the distribution and alignment of cellulose fibrils in cell walls of compression wood (CW) and normal wood (NW) on stem cross-sections of juvenile Picea omorika trees. Our data indicate a decrease in cellulose fibril order in CW compared with NW. Radial and tangential walls differ considerably in both NW and CW. In radial walls, cellulose fibril order shows a gradual decrease from NW to severe CW, in line with the increase in CW severity. This indicates that FDLD analysis of cellulose fibril order in radial cell walls is a valuable method for estimation of CW severity.
PB  - Cambridge Univ Press, New York
T2  - Microscopy and Microanalysis
T1  - Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity
EP  - 367
IS  - 2
SP  - 361
VL  - 22
DO  - 10.1017/S143192761600009X
ER  - 
@article{
author = "Savić, Aleksandar G and Mitrović, Aleksandra Lj. and Donaldson, Lloyd and Simonović Radosavljević, Jasna and Bogdanović Pristov, Jelena and Steinbach, Gabor and Garab, Gyozo and Radotić, Ksenija",
year = "2016",
abstract = "Fluorescence-detected linear dichroism (FDLD) microscopy provides observation of structural order in a microscopic sample and its expression in numerical terms, enabling both quantitative and qualitative comparison among different samples. We applied FDLD microscopy to compare the distribution and alignment of cellulose fibrils in cell walls of compression wood (CW) and normal wood (NW) on stem cross-sections of juvenile Picea omorika trees. Our data indicate a decrease in cellulose fibril order in CW compared with NW. Radial and tangential walls differ considerably in both NW and CW. In radial walls, cellulose fibril order shows a gradual decrease from NW to severe CW, in line with the increase in CW severity. This indicates that FDLD analysis of cellulose fibril order in radial cell walls is a valuable method for estimation of CW severity.",
publisher = "Cambridge Univ Press, New York",
journal = "Microscopy and Microanalysis",
title = "Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity",
pages = "367-361",
number = "2",
volume = "22",
doi = "10.1017/S143192761600009X"
}
Savić, A. G., Mitrović, A. Lj., Donaldson, L., Simonović Radosavljević, J., Bogdanović Pristov, J., Steinbach, G., Garab, G.,& Radotić, K.. (2016). Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity. in Microscopy and Microanalysis
Cambridge Univ Press, New York., 22(2), 361-367.
https://doi.org/10.1017/S143192761600009X
Savić AG, Mitrović AL, Donaldson L, Simonović Radosavljević J, Bogdanović Pristov J, Steinbach G, Garab G, Radotić K. Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity. in Microscopy and Microanalysis. 2016;22(2):361-367.
doi:10.1017/S143192761600009X .
Savić, Aleksandar G, Mitrović, Aleksandra Lj., Donaldson, Lloyd, Simonović Radosavljević, Jasna, Bogdanović Pristov, Jelena, Steinbach, Gabor, Garab, Gyozo, Radotić, Ksenija, "Fluorescence-Detected Linear Dichroism of Wood Cell Walls in Juvenile Serbian Spruce: Estimation of Compression Wood Severity" in Microscopy and Microanalysis, 22, no. 2 (2016):361-367,
https://doi.org/10.1017/S143192761600009X . .
7
4
8

The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System

Milić Komić, Sonja; Bogdanović Pristov, Jelena; Mutavdžić, Dragosav; Savić, Aleksandar G; Spasić, Mihajlo; Spasojević, Ivan

(Amer Chemical Soc, Washington, 2015)

TY  - JOUR
AU  - Milić Komić, Sonja
AU  - Bogdanović Pristov, Jelena
AU  - Mutavdžić, Dragosav
AU  - Savić, Aleksandar G
AU  - Spasić, Mihajlo
AU  - Spasojević, Ivan
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/853
AB  - Herein we compared antioxidative activities (AA) of 25 free L-amino acids (FAA) against Fenton system-mediated hydroxyl radical (HO center dot) production in aqueous solution, and examined the relation between AA and a set of physicochemical properties. The tank order according -to AA was: Tip > notleucine > Phe, Lett > Ile > His >3,4-dihydrOxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydtoxyproline > alpha-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy. AA showed a general positive correlation with hydrophobicity. However, when taken separately, uncharged FAA exhibited strong positive correlation of AA with hydrophobicity whereas charged FAA showed negative or no significant correlation depending on the scale applied. A general strong negative correlation was found between AA and polarity. Steric parameters and hydration numbers correlated positively with AA of rtoripolar side-chain FAA. In addition) a decrease of temperature which promotes hydrophobic hydration resulted in increased AA. This implies that HO-provoked oxidation of FAA is strongly affected by hydrophobic hydration. Our findings are important for the understanding of oxidation processes in natural and waste waters.
PB  - Amer Chemical Soc, Washington
T2  - Environmental Science & Technology
T1  - The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System
EP  - 4254
IS  - 7
SP  - 4245
VL  - 49
DO  - 10.1021/es5053396
ER  - 
@article{
author = "Milić Komić, Sonja and Bogdanović Pristov, Jelena and Mutavdžić, Dragosav and Savić, Aleksandar G and Spasić, Mihajlo and Spasojević, Ivan",
year = "2015",
abstract = "Herein we compared antioxidative activities (AA) of 25 free L-amino acids (FAA) against Fenton system-mediated hydroxyl radical (HO center dot) production in aqueous solution, and examined the relation between AA and a set of physicochemical properties. The tank order according -to AA was: Tip > notleucine > Phe, Lett > Ile > His >3,4-dihydrOxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydtoxyproline > alpha-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy. AA showed a general positive correlation with hydrophobicity. However, when taken separately, uncharged FAA exhibited strong positive correlation of AA with hydrophobicity whereas charged FAA showed negative or no significant correlation depending on the scale applied. A general strong negative correlation was found between AA and polarity. Steric parameters and hydration numbers correlated positively with AA of rtoripolar side-chain FAA. In addition) a decrease of temperature which promotes hydrophobic hydration resulted in increased AA. This implies that HO-provoked oxidation of FAA is strongly affected by hydrophobic hydration. Our findings are important for the understanding of oxidation processes in natural and waste waters.",
publisher = "Amer Chemical Soc, Washington",
journal = "Environmental Science & Technology",
title = "The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System",
pages = "4254-4245",
number = "7",
volume = "49",
doi = "10.1021/es5053396"
}
Milić Komić, S., Bogdanović Pristov, J., Mutavdžić, D., Savić, A. G., Spasić, M.,& Spasojević, I.. (2015). The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System. in Environmental Science & Technology
Amer Chemical Soc, Washington., 49(7), 4245-4254.
https://doi.org/10.1021/es5053396
Milić Komić S, Bogdanović Pristov J, Mutavdžić D, Savić AG, Spasić M, Spasojević I. The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System. in Environmental Science & Technology. 2015;49(7):4245-4254.
doi:10.1021/es5053396 .
Milić Komić, Sonja, Bogdanović Pristov, Jelena, Mutavdžić, Dragosav, Savić, Aleksandar G, Spasić, Mihajlo, Spasojević, Ivan, "The Relationship of Physicochemical Properties to the Antioxidative Activity of Free Amino Acids in Fenton System" in Environmental Science & Technology, 49, no. 7 (2015):4245-4254,
https://doi.org/10.1021/es5053396 . .
19
13
18

Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity

Pesic, Milica; Podolski-Renic, Ana; Stojković, Sonja; Matović, Branko; Zmejkoski, Danica; Kojić, Vesna; Bogdanović, Gordana; Pavicević, Aleksandra; Mojović, Miloš; Savić, Aleksandar G; Milenković, Ivana; Kalauzi, Aleksandar; Radotić, Ksenija

(Elsevier Ireland Ltd, Clare, 2015)

TY  - JOUR
AU  - Pesic, Milica
AU  - Podolski-Renic, Ana
AU  - Stojković, Sonja
AU  - Matović, Branko
AU  - Zmejkoski, Danica
AU  - Kojić, Vesna
AU  - Bogdanović, Gordana
AU  - Pavicević, Aleksandra
AU  - Mojović, Miloš
AU  - Savić, Aleksandar G
AU  - Milenković, Ivana
AU  - Kalauzi, Aleksandar
AU  - Radotić, Ksenija
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/931
AB  - Data on medical applications of cerium oxide nanoparticles CeO2 (CONP) are promising, yet information regarding their action in cells is incomplete and there are conflicting reports about in vitro toxicity. Herein, we have studied cytotoxic effect of CONP in several cancer and normal cell lines and their potential to change intracellular redox status. The IC50 was achieved only in two of eight tested cell lines, melanoma 518A2 and colorectal adenocarcinoma HT-29. Self-propagating room temperature method was applied to produce CONP with an average crystalline size of 4 nm. The results confirmed presence of Ce3+ and O2- vacancies. The induction of cell death by CONP and the production of reactive oxygen species (ROS) were analyzed by flow-cytometry. Free radicals related antioxidant capacity of the cells was studied by the reduction of stable free radical TEMPONE using electron spin resonance spectroscopy. CONP showed low or moderate cytotoxicity in cancer cell lines: adenocarcinoma DLD1 and multi-drug resistant DLD1-TxR, non-small cell lung carcinoma NCI-H460 and multi-drug resistant NCI-H460/R, while normal cell lines (keratinocytes HaCaT, lung fetal fibroblasts MRC-5) were insensitive. The most sensitive were 518A2 melanoma and HT-29 colorectal adenocarcinoma cell lines, with the IC50 values being between 100 and 200 mu M. Decreased rate of TEMPONE reduction and increased production of certain ROS species (peroxynitrite and hydrogen peroxide anion) indicates that free radical metabolism, thus redox status was changed, and antioxidant capacity damaged in the CONP treated 518A2 and HT-29 cells. In conclusion, changes in intracellular redox status induced by CONP are partly attributed to the prooxidant activity of the nanoparticles. Further, ROS induced cell damages might eventually lead to the cell death. However, low inhibitory potential of CONP in the other human cell lines tested indicates that CONP may be safe for human usage in industry and medicine.
PB  - Elsevier Ireland Ltd, Clare
T2  - Chemico-Biological Interactions
T1  - Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity
EP  - 93
SP  - 85
VL  - 232
DO  - 10.1016/j.cbi.2015.03.013
ER  - 
@article{
author = "Pesic, Milica and Podolski-Renic, Ana and Stojković, Sonja and Matović, Branko and Zmejkoski, Danica and Kojić, Vesna and Bogdanović, Gordana and Pavicević, Aleksandra and Mojović, Miloš and Savić, Aleksandar G and Milenković, Ivana and Kalauzi, Aleksandar and Radotić, Ksenija",
year = "2015",
abstract = "Data on medical applications of cerium oxide nanoparticles CeO2 (CONP) are promising, yet information regarding their action in cells is incomplete and there are conflicting reports about in vitro toxicity. Herein, we have studied cytotoxic effect of CONP in several cancer and normal cell lines and their potential to change intracellular redox status. The IC50 was achieved only in two of eight tested cell lines, melanoma 518A2 and colorectal adenocarcinoma HT-29. Self-propagating room temperature method was applied to produce CONP with an average crystalline size of 4 nm. The results confirmed presence of Ce3+ and O2- vacancies. The induction of cell death by CONP and the production of reactive oxygen species (ROS) were analyzed by flow-cytometry. Free radicals related antioxidant capacity of the cells was studied by the reduction of stable free radical TEMPONE using electron spin resonance spectroscopy. CONP showed low or moderate cytotoxicity in cancer cell lines: adenocarcinoma DLD1 and multi-drug resistant DLD1-TxR, non-small cell lung carcinoma NCI-H460 and multi-drug resistant NCI-H460/R, while normal cell lines (keratinocytes HaCaT, lung fetal fibroblasts MRC-5) were insensitive. The most sensitive were 518A2 melanoma and HT-29 colorectal adenocarcinoma cell lines, with the IC50 values being between 100 and 200 mu M. Decreased rate of TEMPONE reduction and increased production of certain ROS species (peroxynitrite and hydrogen peroxide anion) indicates that free radical metabolism, thus redox status was changed, and antioxidant capacity damaged in the CONP treated 518A2 and HT-29 cells. In conclusion, changes in intracellular redox status induced by CONP are partly attributed to the prooxidant activity of the nanoparticles. Further, ROS induced cell damages might eventually lead to the cell death. However, low inhibitory potential of CONP in the other human cell lines tested indicates that CONP may be safe for human usage in industry and medicine.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Chemico-Biological Interactions",
title = "Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity",
pages = "93-85",
volume = "232",
doi = "10.1016/j.cbi.2015.03.013"
}
Pesic, M., Podolski-Renic, A., Stojković, S., Matović, B., Zmejkoski, D., Kojić, V., Bogdanović, G., Pavicević, A., Mojović, M., Savić, A. G., Milenković, I., Kalauzi, A.,& Radotić, K.. (2015). Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity. in Chemico-Biological Interactions
Elsevier Ireland Ltd, Clare., 232, 85-93.
https://doi.org/10.1016/j.cbi.2015.03.013
Pesic M, Podolski-Renic A, Stojković S, Matović B, Zmejkoski D, Kojić V, Bogdanović G, Pavicević A, Mojović M, Savić AG, Milenković I, Kalauzi A, Radotić K. Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity. in Chemico-Biological Interactions. 2015;232:85-93.
doi:10.1016/j.cbi.2015.03.013 .
Pesic, Milica, Podolski-Renic, Ana, Stojković, Sonja, Matović, Branko, Zmejkoski, Danica, Kojić, Vesna, Bogdanović, Gordana, Pavicević, Aleksandra, Mojović, Miloš, Savić, Aleksandar G, Milenković, Ivana, Kalauzi, Aleksandar, Radotić, Ksenija, "Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity" in Chemico-Biological Interactions, 232 (2015):85-93,
https://doi.org/10.1016/j.cbi.2015.03.013 . .
136
85
136

New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012

Pejin, Boris; Jovanović, Katarina K; Savić, Aleksandar G

(Bentham Science Publ Ltd, Sharjah, 2015)

TY  - JOUR
AU  - Pejin, Boris
AU  - Jovanović, Katarina K
AU  - Savić, Aleksandar G
PY  - 2015
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/851
AB  - This review covers the 2003-2012 literature data published for natural products originating from marine red algae. The focus is on new antitumour substances, together with details related to the organism sourced. It emphasises 14 promising compounds (isolated from 13 species) whose chemical structures are briefly discussed.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Mini-Reviews in Medicinal Chemistry
T1  - New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012
EP  - 730
IS  - 9
SP  - 720
VL  - 15
DO  - 10.2174/1389557515666150511152251
ER  - 
@article{
author = "Pejin, Boris and Jovanović, Katarina K and Savić, Aleksandar G",
year = "2015",
abstract = "This review covers the 2003-2012 literature data published for natural products originating from marine red algae. The focus is on new antitumour substances, together with details related to the organism sourced. It emphasises 14 promising compounds (isolated from 13 species) whose chemical structures are briefly discussed.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Mini-Reviews in Medicinal Chemistry",
title = "New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012",
pages = "730-720",
number = "9",
volume = "15",
doi = "10.2174/1389557515666150511152251"
}
Pejin, B., Jovanović, K. K.,& Savić, A. G.. (2015). New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012. in Mini-Reviews in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 15(9), 720-730.
https://doi.org/10.2174/1389557515666150511152251
Pejin B, Jovanović KK, Savić AG. New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012. in Mini-Reviews in Medicinal Chemistry. 2015;15(9):720-730.
doi:10.2174/1389557515666150511152251 .
Pejin, Boris, Jovanović, Katarina K, Savić, Aleksandar G, "New Antitumour Natural Products from Marine Red Algae: Covering the Period from 2003 to 2012" in Mini-Reviews in Medicinal Chemistry, 15, no. 9 (2015):720-730,
https://doi.org/10.2174/1389557515666150511152251 . .
12
5
13

Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis

Adamović, Saša; Savić, Aleksandar; Milosavljević, Milan; Spasić, Slađana

(Univerzitet Singidunum, Beograd, 2014)

TY  - CONF
AU  - Adamović, Saša
AU  - Savić, Aleksandar
AU  - Milosavljević, Milan
AU  - Spasić, Slađana
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2389
AB  - Novel method for personal identification, based on adaptive size neighborhood entropy of iris images, was proposed. Through the process of segmentation, iris was extracted from other regions of the human eye, geometrically transformed and normalized. Entropy calculations performed for different neighborhood sizes allows simultaneous distinguishing of fine and global iris texture. Described method also allows recognition of images which contain artifacts and their removal from further analysis after application of principal component analysis (PCA). In the last analytical step, linear discriminant analysis (LDA) with training vector set was applied, allowing rigorous classification. Described procedure is suitable for the application in security systems with small number of authorized persons and a high degree of safety.
PB  - Univerzitet Singidunum, Beograd
C3  - Sinteza 2014 - Impact of the Internet on Business Activities in Serbia and Worldwide
T1  - Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis
DO  - 10.15308/sinteza-2014-658-660
ER  - 
@conference{
author = "Adamović, Saša and Savić, Aleksandar and Milosavljević, Milan and Spasić, Slađana",
year = "2014",
abstract = "Novel method for personal identification, based on adaptive size neighborhood entropy of iris images, was proposed. Through the process of segmentation, iris was extracted from other regions of the human eye, geometrically transformed and normalized. Entropy calculations performed for different neighborhood sizes allows simultaneous distinguishing of fine and global iris texture. Described method also allows recognition of images which contain artifacts and their removal from further analysis after application of principal component analysis (PCA). In the last analytical step, linear discriminant analysis (LDA) with training vector set was applied, allowing rigorous classification. Described procedure is suitable for the application in security systems with small number of authorized persons and a high degree of safety.",
publisher = "Univerzitet Singidunum, Beograd",
journal = "Sinteza 2014 - Impact of the Internet on Business Activities in Serbia and Worldwide",
title = "Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis",
doi = "10.15308/sinteza-2014-658-660"
}
Adamović, S., Savić, A., Milosavljević, M.,& Spasić, S.. (2014). Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis. in Sinteza 2014 - Impact of the Internet on Business Activities in Serbia and Worldwide
Univerzitet Singidunum, Beograd..
https://doi.org/10.15308/sinteza-2014-658-660
Adamović S, Savić A, Milosavljević M, Spasić S. Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis. in Sinteza 2014 - Impact of the Internet on Business Activities in Serbia and Worldwide. 2014;.
doi:10.15308/sinteza-2014-658-660 .
Adamović, Saša, Savić, Aleksandar, Milosavljević, Milan, Spasić, Slađana, "Texture analysis of iris biometrics based on adaptive size neighborhood entropy and linear discriminant analysis" in Sinteza 2014 - Impact of the Internet on Business Activities in Serbia and Worldwide (2014),
https://doi.org/10.15308/sinteza-2014-658-660 . .
1

Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces

Algarra, Manuel; Radotić, Ksenija; Kalauzi, Aleksandar; Mutavdžić, Dragosav; Savić, Aleksandar G; Jimenez-Jimenez, Jose; Rodriguez-Castellon, Enrique; Esteves da Silva, Joaquim C.G.; Jose Guerrero-Gonzalez, Juan

(Elsevier, Amsterdam, 2014)

TY  - JOUR
AU  - Algarra, Manuel
AU  - Radotić, Ksenija
AU  - Kalauzi, Aleksandar
AU  - Mutavdžić, Dragosav
AU  - Savić, Aleksandar G
AU  - Jimenez-Jimenez, Jose
AU  - Rodriguez-Castellon, Enrique
AU  - Esteves da Silva, Joaquim C.G.
AU  - Jose Guerrero-Gonzalez, Juan
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/794
AB  - A fluorescent nanocomposite based on the inclusion of CdSe quantum dots in porous phosphate heterostructures, functionalized with amino groups (PPH-NH2"CdSe), was synthesized, characterized and used for fingerprint detection. The main scopes of this work were first to develop a friendly chemical powder for detecting latent fingerprints, especially in non-porous surfaces; their further intercalation in PPH structure enables not to spread the fluorescent nanoparticles, for that reason very good fluorescent images can be obtained. The fingerprints, obtained on different non-porous surfaces such as iron tweezers, mobile telephone screen and magnetic band of a credit card, treated with this powder emit a pale orange luminescence under ultraviolet excitation. A further image processing consists of contrast enhancement that allows obtaining positive matches according to the information supplied from a police database, and showed to be more effective than that obtained with the non-processed images. Experimental results illustrate the effectiveness of proposed methods.
PB  - Elsevier, Amsterdam
T2  - Analytica Chimica Acta
T1  - Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces
EP  - 235
SP  - 228
VL  - 812
DO  - 10.1016/j.aca.2014.01.015
ER  - 
@article{
author = "Algarra, Manuel and Radotić, Ksenija and Kalauzi, Aleksandar and Mutavdžić, Dragosav and Savić, Aleksandar G and Jimenez-Jimenez, Jose and Rodriguez-Castellon, Enrique and Esteves da Silva, Joaquim C.G. and Jose Guerrero-Gonzalez, Juan",
year = "2014",
abstract = "A fluorescent nanocomposite based on the inclusion of CdSe quantum dots in porous phosphate heterostructures, functionalized with amino groups (PPH-NH2"CdSe), was synthesized, characterized and used for fingerprint detection. The main scopes of this work were first to develop a friendly chemical powder for detecting latent fingerprints, especially in non-porous surfaces; their further intercalation in PPH structure enables not to spread the fluorescent nanoparticles, for that reason very good fluorescent images can be obtained. The fingerprints, obtained on different non-porous surfaces such as iron tweezers, mobile telephone screen and magnetic band of a credit card, treated with this powder emit a pale orange luminescence under ultraviolet excitation. A further image processing consists of contrast enhancement that allows obtaining positive matches according to the information supplied from a police database, and showed to be more effective than that obtained with the non-processed images. Experimental results illustrate the effectiveness of proposed methods.",
publisher = "Elsevier, Amsterdam",
journal = "Analytica Chimica Acta",
title = "Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces",
pages = "235-228",
volume = "812",
doi = "10.1016/j.aca.2014.01.015"
}
Algarra, M., Radotić, K., Kalauzi, A., Mutavdžić, D., Savić, A. G., Jimenez-Jimenez, J., Rodriguez-Castellon, E., Esteves da Silva, J. C.G.,& Jose Guerrero-Gonzalez, J.. (2014). Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces. in Analytica Chimica Acta
Elsevier, Amsterdam., 812, 228-235.
https://doi.org/10.1016/j.aca.2014.01.015
Algarra M, Radotić K, Kalauzi A, Mutavdžić D, Savić AG, Jimenez-Jimenez J, Rodriguez-Castellon E, Esteves da Silva JC, Jose Guerrero-Gonzalez J. Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces. in Analytica Chimica Acta. 2014;812:228-235.
doi:10.1016/j.aca.2014.01.015 .
Algarra, Manuel, Radotić, Ksenija, Kalauzi, Aleksandar, Mutavdžić, Dragosav, Savić, Aleksandar G, Jimenez-Jimenez, Jose, Rodriguez-Castellon, Enrique, Esteves da Silva, Joaquim C.G., Jose Guerrero-Gonzalez, Juan, "Fingerprint detection and using intercalated CdSe nanoparticles on non-porous surfaces" in Analytica Chimica Acta, 812 (2014):228-235,
https://doi.org/10.1016/j.aca.2014.01.015 . .
36
14
37

Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata

Pejin, Boris; Nakarada, Dura; Novaković, Miroslav; Tešević, Vele; Savić, Aleksandar G; Radotić, Ksenija; Mojović, Miloš

(Taylor & Francis Ltd, Abingdon, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Nakarada, Dura
AU  - Novaković, Miroslav
AU  - Tešević, Vele
AU  - Savić, Aleksandar G
AU  - Radotić, Ksenija
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/773
AB  - Two volatile samples of the bryozoan Hyalinella punctata (seasonally collected from the same locality) were isolated (hydrodistillation, Clevenger apparatus), identified (GC and GC-MS) and screened in vitro (EPR) for anti-hydroxyl radical activity. The main components of sample 1 (2-ethyl-1-hexanol 37.00%, dodecanol 21.40% and hexanal 8.40%) and sample 2 (2-ethyl-1-hexanol 30.50%, 7-tridecanol 24.60% and 1-hexadecanol 11.80%) were relatively similar. However, more components were present in the sample 2 (17 and 25, respectively). EPR measurements indicated significant anti-hydroxyl radical activity of the both samples (75.00 +/- 6.00% and 87.00 +/- 8.00%, respectively) whereas the generation of other types of free radicals in reaction with hydroxyl radicals was not observed. According to the best of our knowledge, this is the first report of 31 organic compounds from the phylum Bryozoa. Alcohols, aldehydes, ketones, esters and ethers of lower molecular mass appear to be characteristic for the volatiles of these organisms commonly known as moss animals.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata
EP  - 1475
IS  - 18
SP  - 1471
VL  - 28
DO  - 10.1080/14786419.2014.905565
ER  - 
@article{
author = "Pejin, Boris and Nakarada, Dura and Novaković, Miroslav and Tešević, Vele and Savić, Aleksandar G and Radotić, Ksenija and Mojović, Miloš",
year = "2014",
abstract = "Two volatile samples of the bryozoan Hyalinella punctata (seasonally collected from the same locality) were isolated (hydrodistillation, Clevenger apparatus), identified (GC and GC-MS) and screened in vitro (EPR) for anti-hydroxyl radical activity. The main components of sample 1 (2-ethyl-1-hexanol 37.00%, dodecanol 21.40% and hexanal 8.40%) and sample 2 (2-ethyl-1-hexanol 30.50%, 7-tridecanol 24.60% and 1-hexadecanol 11.80%) were relatively similar. However, more components were present in the sample 2 (17 and 25, respectively). EPR measurements indicated significant anti-hydroxyl radical activity of the both samples (75.00 +/- 6.00% and 87.00 +/- 8.00%, respectively) whereas the generation of other types of free radicals in reaction with hydroxyl radicals was not observed. According to the best of our knowledge, this is the first report of 31 organic compounds from the phylum Bryozoa. Alcohols, aldehydes, ketones, esters and ethers of lower molecular mass appear to be characteristic for the volatiles of these organisms commonly known as moss animals.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata",
pages = "1475-1471",
number = "18",
volume = "28",
doi = "10.1080/14786419.2014.905565"
}
Pejin, B., Nakarada, D., Novaković, M., Tešević, V., Savić, A. G., Radotić, K.,& Mojović, M.. (2014). Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(18), 1471-1475.
https://doi.org/10.1080/14786419.2014.905565
Pejin B, Nakarada D, Novaković M, Tešević V, Savić AG, Radotić K, Mojović M. Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata. in Natural Product Research. 2014;28(18):1471-1475.
doi:10.1080/14786419.2014.905565 .
Pejin, Boris, Nakarada, Dura, Novaković, Miroslav, Tešević, Vele, Savić, Aleksandar G, Radotić, Ksenija, Mojović, Miloš, "Antioxidant volatiles of the freshwater bryozoan Hyalinella punctata" in Natural Product Research, 28, no. 18 (2014):1471-1475,
https://doi.org/10.1080/14786419.2014.905565 . .
4
3
5

Further in vitro evaluation of antiradical and antimicrobial activities of phytol

Pejin, Boris; Savić, Aleksandar G; Soković, Marina; Glamočlija, Jasmina; Ciric, Ana D; Nikolic, Milos MN; Radotić, Ksenija; Mojović, Miloš

(Taylor & Francis Ltd, Abingdon, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Soković, Marina
AU  - Glamočlija, Jasmina
AU  - Ciric, Ana D
AU  - Nikolic, Milos MN
AU  - Radotić, Ksenija
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/759
AB  - The antiradical activity of phytol was evaluated by electron paramagnetic resonance towards hydroxyl radical (root OH), superoxide anion radical (), methoxy radical (root CH2OH), carbon-dioxide anion radical (), as well as towards nitric-oxide radical (root NO) and 2,2-diphenyl-1-picrylhydrazyl (root DPPH) radical. It reduced the production of all tested radicals showing more promising activity against , root CH2OH and root DPPH radicals (56%, 50% and 48%, respectively) in comparison with root NO, and root OH radicals (38%, 23% and 15%, respectively). The antimicrobial activity of phytol was evaluated by the microdilution method against eight bacterial and eight fungal strains. To varying degrees, it was proven to be active against all tested bacteria and fungi (MIC 0.003-0.038mg/mL and MBC 0.013-0.052mg/mL, MIC 0.008-0.016mg/mL and MFC 0.090-0.520mg/mL, respectively). According to the obtained results, medical foods containing phytol may support development of new therapies for heart disease.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Further in vitro evaluation of antiradical and antimicrobial activities of phytol
EP  - 376
IS  - 6
SP  - 372
VL  - 28
DO  - 10.1080/14786419.2013.869692
ER  - 
@article{
author = "Pejin, Boris and Savić, Aleksandar G and Soković, Marina and Glamočlija, Jasmina and Ciric, Ana D and Nikolic, Milos MN and Radotić, Ksenija and Mojović, Miloš",
year = "2014",
abstract = "The antiradical activity of phytol was evaluated by electron paramagnetic resonance towards hydroxyl radical (root OH), superoxide anion radical (), methoxy radical (root CH2OH), carbon-dioxide anion radical (), as well as towards nitric-oxide radical (root NO) and 2,2-diphenyl-1-picrylhydrazyl (root DPPH) radical. It reduced the production of all tested radicals showing more promising activity against , root CH2OH and root DPPH radicals (56%, 50% and 48%, respectively) in comparison with root NO, and root OH radicals (38%, 23% and 15%, respectively). The antimicrobial activity of phytol was evaluated by the microdilution method against eight bacterial and eight fungal strains. To varying degrees, it was proven to be active against all tested bacteria and fungi (MIC 0.003-0.038mg/mL and MBC 0.013-0.052mg/mL, MIC 0.008-0.016mg/mL and MFC 0.090-0.520mg/mL, respectively). According to the obtained results, medical foods containing phytol may support development of new therapies for heart disease.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Further in vitro evaluation of antiradical and antimicrobial activities of phytol",
pages = "376-372",
number = "6",
volume = "28",
doi = "10.1080/14786419.2013.869692"
}
Pejin, B., Savić, A. G., Soković, M., Glamočlija, J., Ciric, A. D., Nikolic, M. M., Radotić, K.,& Mojović, M.. (2014). Further in vitro evaluation of antiradical and antimicrobial activities of phytol. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(6), 372-376.
https://doi.org/10.1080/14786419.2013.869692
Pejin B, Savić AG, Soković M, Glamočlija J, Ciric AD, Nikolic MM, Radotić K, Mojović M. Further in vitro evaluation of antiradical and antimicrobial activities of phytol. in Natural Product Research. 2014;28(6):372-376.
doi:10.1080/14786419.2013.869692 .
Pejin, Boris, Savić, Aleksandar G, Soković, Marina, Glamočlija, Jasmina, Ciric, Ana D, Nikolic, Milos MN, Radotić, Ksenija, Mojović, Miloš, "Further in vitro evaluation of antiradical and antimicrobial activities of phytol" in Natural Product Research, 28, no. 6 (2014):372-376,
https://doi.org/10.1080/14786419.2013.869692 . .
1
119
88
121

In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches

Pejin, Boris; Savić, Aleksandar G; Petković, Milena M; Radotić, Ksenija; Mojović, Miloš

(Wiley, Hoboken, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Petković, Milena M
AU  - Radotić, Ksenija
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/752
AB  - Fructooligosaccharides (FOS) are bioactive oligosaccharide fructans with beneficial health effects. Anti-hydroxyl radical activity is an important factor in the description of antioxidant capacity of any natural product. The aim of this study was to estimate in vitro anti-hydroxyl radical activity of the FOS 1-kestose and nystose by electron paramagnetic resonance spectroscopy (EPR) and fluorescence spectroscopy (FS) followed by a theoretical approach based on quantum chemistry calculations. A significant anti-hydroxyl radical potential of both compounds was observed (72% and 78% by EPR and 69% and 74% by FS, respectively), indicating the nystose to be a more active natural product. In addition, the computational results have confirmed that nystose follows the same pattern previously shown for 1-kestose, that is, that carbohydrates can react with hydroxyl radical. It is well known that FOS belong to cardioprotective nutraceuticals, so the study may be of some interest to research in heart disease.
PB  - Wiley, Hoboken
T2  - International Journal of Food Science and Technology
T1  - In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches
EP  - 1505
IS  - 6
SP  - 1500
VL  - 49
DO  - 10.1111/ijfs.12445
ER  - 
@article{
author = "Pejin, Boris and Savić, Aleksandar G and Petković, Milena M and Radotić, Ksenija and Mojović, Miloš",
year = "2014",
abstract = "Fructooligosaccharides (FOS) are bioactive oligosaccharide fructans with beneficial health effects. Anti-hydroxyl radical activity is an important factor in the description of antioxidant capacity of any natural product. The aim of this study was to estimate in vitro anti-hydroxyl radical activity of the FOS 1-kestose and nystose by electron paramagnetic resonance spectroscopy (EPR) and fluorescence spectroscopy (FS) followed by a theoretical approach based on quantum chemistry calculations. A significant anti-hydroxyl radical potential of both compounds was observed (72% and 78% by EPR and 69% and 74% by FS, respectively), indicating the nystose to be a more active natural product. In addition, the computational results have confirmed that nystose follows the same pattern previously shown for 1-kestose, that is, that carbohydrates can react with hydroxyl radical. It is well known that FOS belong to cardioprotective nutraceuticals, so the study may be of some interest to research in heart disease.",
publisher = "Wiley, Hoboken",
journal = "International Journal of Food Science and Technology",
title = "In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches",
pages = "1505-1500",
number = "6",
volume = "49",
doi = "10.1111/ijfs.12445"
}
Pejin, B., Savić, A. G., Petković, M. M., Radotić, K.,& Mojović, M.. (2014). In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches. in International Journal of Food Science and Technology
Wiley, Hoboken., 49(6), 1500-1505.
https://doi.org/10.1111/ijfs.12445
Pejin B, Savić AG, Petković MM, Radotić K, Mojović M. In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches. in International Journal of Food Science and Technology. 2014;49(6):1500-1505.
doi:10.1111/ijfs.12445 .
Pejin, Boris, Savić, Aleksandar G, Petković, Milena M, Radotić, Ksenija, Mojović, Miloš, "In vitro anti-hydroxyl radical activity of the fructooligosaccharides 1-kestose and nystose using spectroscopic and computational approaches" in International Journal of Food Science and Technology, 49, no. 6 (2014):1500-1505,
https://doi.org/10.1111/ijfs.12445 . .
14
7
13

Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension

Kesic, Srdjan; Nikolić, Ljiljana M.; Savić, Aleksandar G; Petković, Branka; Spasić, Slađana

(General Physiol And Biophysics, Bratislava, 2014)

TY  - JOUR
AU  - Kesic, Srdjan
AU  - Nikolić, Ljiljana M.
AU  - Savić, Aleksandar G
AU  - Petković, Branka
AU  - Spasić, Slađana
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/786
AB  - Aim of this study was to investigate the application of normalized mean of the empirical Higuchi fractal dimension (FD) distributions, as a new approach to analyze the spontaneous bioelectrical activity of garden snail (Helix pomatia) Br neuron. The effect of ouabain on modulation of Br neuron bursting activity before and after the exposure to 10 mT static magnetic field (SMF) was observed by analyzing the following parameters: action potential (AP), interspike interval (ISI) and interbursting interval (IBI) components. Normalized mean of the empirical FD distributions were formed for the following experimental conditions: Control 1, Ouabain 1, Control 2, SMF 2, ASMF 2, Control 3, SMF 3 and Ouabain ASMF 3. Our main results have shown that ouabain without SMF induced increase in participation of AP and a decrease in participation of IBI components compared to the first control condition. However, in the presence of 10 mT SMF, ouabain-induced changes of measured parameters of Br neuron activity were less pronounced compared to the third control condition. We have shown that normalized mean of the empirical FD distributions is a useful method for detecting the changes in AP, ISI, and IBI components of complex bursting activity in altered physiological states.
PB  - General Physiol And Biophysics, Bratislava
T2  - General Physiology and Biophysics
T1  - Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension
EP  - 344
IS  - 3
SP  - 335
VL  - 33
DO  - 10.4149/gpb_2014010
ER  - 
@article{
author = "Kesic, Srdjan and Nikolić, Ljiljana M. and Savić, Aleksandar G and Petković, Branka and Spasić, Slađana",
year = "2014",
abstract = "Aim of this study was to investigate the application of normalized mean of the empirical Higuchi fractal dimension (FD) distributions, as a new approach to analyze the spontaneous bioelectrical activity of garden snail (Helix pomatia) Br neuron. The effect of ouabain on modulation of Br neuron bursting activity before and after the exposure to 10 mT static magnetic field (SMF) was observed by analyzing the following parameters: action potential (AP), interspike interval (ISI) and interbursting interval (IBI) components. Normalized mean of the empirical FD distributions were formed for the following experimental conditions: Control 1, Ouabain 1, Control 2, SMF 2, ASMF 2, Control 3, SMF 3 and Ouabain ASMF 3. Our main results have shown that ouabain without SMF induced increase in participation of AP and a decrease in participation of IBI components compared to the first control condition. However, in the presence of 10 mT SMF, ouabain-induced changes of measured parameters of Br neuron activity were less pronounced compared to the third control condition. We have shown that normalized mean of the empirical FD distributions is a useful method for detecting the changes in AP, ISI, and IBI components of complex bursting activity in altered physiological states.",
publisher = "General Physiol And Biophysics, Bratislava",
journal = "General Physiology and Biophysics",
title = "Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension",
pages = "344-335",
number = "3",
volume = "33",
doi = "10.4149/gpb_2014010"
}
Kesic, S., Nikolić, L. M., Savić, A. G., Petković, B.,& Spasić, S.. (2014). Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension. in General Physiology and Biophysics
General Physiol And Biophysics, Bratislava., 33(3), 335-344.
https://doi.org/10.4149/gpb_2014010
Kesic S, Nikolić LM, Savić AG, Petković B, Spasić S. Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension. in General Physiology and Biophysics. 2014;33(3):335-344.
doi:10.4149/gpb_2014010 .
Kesic, Srdjan, Nikolić, Ljiljana M., Savić, Aleksandar G, Petković, Branka, Spasić, Slađana, "Ouabain modulation of snail Br neuron bursting activity after the exposure to 10 mT static magnetic field revealed by Higuchi fractal dimension" in General Physiology and Biophysics, 33, no. 3 (2014):335-344,
https://doi.org/10.4149/gpb_2014010 . .
5
4
6

A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity

Pejin, Boris; Savić, Aleksandar G; Hegediš, Aleksandar; Karaman, Ivo; Horvatović, Mladen; Mojović, Miloš

(Taylor & Francis Ltd, Abingdon, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Hegediš, Aleksandar
AU  - Karaman, Ivo
AU  - Horvatović, Mladen
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/770
AB  - The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (zOH), superoxide anion (center dot O-2(-)), methoxy (center dot CH2OH), carbon-dioxide anion (center dot CO2-), nitric-oxide (center dot NO) and 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH) radicals. The extracts reduced the production of all tested radicals but to a varying degree. The better activity was observed against center dot CO2- and center dot CH2OH radicals (54 +/- 5% and 44 +/- 4%, and 58 +/- 6% and 22 +/- 2%, respectively) than towards center dot DPPH, center dot NO, center dot OH and center dot O-2(-) radicals (59 +/- 6% and 1.0 +/- 0.1%, 46 +/- 5% and 14 +/- 1%, 7.0 +/- 0.5% and 34 +/- 3%, and 33 +/- 3% and 0%, respectively). FTIR spectra of the both extracts indicate the presence of cyclic peptides and polypeptides which might be responsible for the observed activity. According to the experimental data obtained, H. punctata water extract may be considered as a novel promising resource of natural products with anti center dot CO2- radical activity.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity
EP  - 2060
IS  - 22
SP  - 2057
VL  - 28
DO  - 10.1080/14786419.2014.921788
ER  - 
@article{
author = "Pejin, Boris and Savić, Aleksandar G and Hegediš, Aleksandar and Karaman, Ivo and Horvatović, Mladen and Mojović, Miloš",
year = "2014",
abstract = "The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (zOH), superoxide anion (center dot O-2(-)), methoxy (center dot CH2OH), carbon-dioxide anion (center dot CO2-), nitric-oxide (center dot NO) and 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH) radicals. The extracts reduced the production of all tested radicals but to a varying degree. The better activity was observed against center dot CO2- and center dot CH2OH radicals (54 +/- 5% and 44 +/- 4%, and 58 +/- 6% and 22 +/- 2%, respectively) than towards center dot DPPH, center dot NO, center dot OH and center dot O-2(-) radicals (59 +/- 6% and 1.0 +/- 0.1%, 46 +/- 5% and 14 +/- 1%, 7.0 +/- 0.5% and 34 +/- 3%, and 33 +/- 3% and 0%, respectively). FTIR spectra of the both extracts indicate the presence of cyclic peptides and polypeptides which might be responsible for the observed activity. According to the experimental data obtained, H. punctata water extract may be considered as a novel promising resource of natural products with anti center dot CO2- radical activity.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity",
pages = "2060-2057",
number = "22",
volume = "28",
doi = "10.1080/14786419.2014.921788"
}
Pejin, B., Savić, A. G., Hegediš, A., Karaman, I., Horvatović, M.,& Mojović, M.. (2014). A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(22), 2057-2060.
https://doi.org/10.1080/14786419.2014.921788
Pejin B, Savić AG, Hegediš A, Karaman I, Horvatović M, Mojović M. A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity. in Natural Product Research. 2014;28(22):2057-2060.
doi:10.1080/14786419.2014.921788 .
Pejin, Boris, Savić, Aleksandar G, Hegediš, Aleksandar, Karaman, Ivo, Horvatović, Mladen, Mojović, Miloš, "A bryozoan species may offer novel antioxidants with anti-carbon-dioxide anion radical activity" in Natural Product Research, 28, no. 22 (2014):2057-2060,
https://doi.org/10.1080/14786419.2014.921788 . .
3
3

Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat

Bukvicki, Danka R; Stojković, Dejan S; Soković, Marina; Vannini, Lucia; Montanari, Chiara; Pejin, Boris; Savić, Aleksandar G; Veljic, Milan M; Grujic, Slavica; Marin, Petar D.

(Elsevier Sci Ltd, Oxford, 2014)

TY  - JOUR
AU  - Bukvicki, Danka R
AU  - Stojković, Dejan S
AU  - Soković, Marina
AU  - Vannini, Lucia
AU  - Montanari, Chiara
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Veljic, Milan M
AU  - Grujic, Slavica
AU  - Marin, Petar D.
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/760
AB  - The dominant compounds in Satureja horvatii oil were p-cymene (33.14%), thymol (26.11%) and thymol methyl ether (15.08%). The minimum inhibitory concentration (MIC) varied from 0.03 to 0.57 mg/mL for bacteria, and from 0.56 to 2.23 mg/mL for yeast strains, while minimum bactericidal/yeast-cidal concentration (MBC/MYC) varied from 0.07 to 1.15 mg/mL and 1.11 to 5.57 mg/mL for bacteria and yeasts, respectively. The antiradical potential of the essential oil was evaluated using hydroxyl radical (center dot OH) generated in Fenton reaction. The meat preserving potential of essential oil from Satureja horvatii was investigated against L monocytogenes. Essential oil successfully inhibited development of L monocytogenes in pork meat. Sensorial evaluation on flavor and color of meat was performed. The color and flavor of meat treated with essential oil improved after 4 days of storage. S. horvatii essential oil can act as a potent inhibitor of food spoiling microorganisms, in meat products and also can be a useful source of natural antioxidants.
PB  - Elsevier Sci Ltd, Oxford
T2  - Meat Science
T1  - Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat
EP  - 1360
IS  - 3
SP  - 1355
VL  - 96
DO  - 10.1016/j.meatsci.2013.11.024
ER  - 
@article{
author = "Bukvicki, Danka R and Stojković, Dejan S and Soković, Marina and Vannini, Lucia and Montanari, Chiara and Pejin, Boris and Savić, Aleksandar G and Veljic, Milan M and Grujic, Slavica and Marin, Petar D.",
year = "2014",
abstract = "The dominant compounds in Satureja horvatii oil were p-cymene (33.14%), thymol (26.11%) and thymol methyl ether (15.08%). The minimum inhibitory concentration (MIC) varied from 0.03 to 0.57 mg/mL for bacteria, and from 0.56 to 2.23 mg/mL for yeast strains, while minimum bactericidal/yeast-cidal concentration (MBC/MYC) varied from 0.07 to 1.15 mg/mL and 1.11 to 5.57 mg/mL for bacteria and yeasts, respectively. The antiradical potential of the essential oil was evaluated using hydroxyl radical (center dot OH) generated in Fenton reaction. The meat preserving potential of essential oil from Satureja horvatii was investigated against L monocytogenes. Essential oil successfully inhibited development of L monocytogenes in pork meat. Sensorial evaluation on flavor and color of meat was performed. The color and flavor of meat treated with essential oil improved after 4 days of storage. S. horvatii essential oil can act as a potent inhibitor of food spoiling microorganisms, in meat products and also can be a useful source of natural antioxidants.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Meat Science",
title = "Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat",
pages = "1360-1355",
number = "3",
volume = "96",
doi = "10.1016/j.meatsci.2013.11.024"
}
Bukvicki, D. R., Stojković, D. S., Soković, M., Vannini, L., Montanari, C., Pejin, B., Savić, A. G., Veljic, M. M., Grujic, S.,& Marin, P. D.. (2014). Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. in Meat Science
Elsevier Sci Ltd, Oxford., 96(3), 1355-1360.
https://doi.org/10.1016/j.meatsci.2013.11.024
Bukvicki DR, Stojković DS, Soković M, Vannini L, Montanari C, Pejin B, Savić AG, Veljic MM, Grujic S, Marin PD. Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat. in Meat Science. 2014;96(3):1355-1360.
doi:10.1016/j.meatsci.2013.11.024 .
Bukvicki, Danka R, Stojković, Dejan S, Soković, Marina, Vannini, Lucia, Montanari, Chiara, Pejin, Boris, Savić, Aleksandar G, Veljic, Milan M, Grujic, Slavica, Marin, Petar D., "Satureja horvatii essential oil: In vitro antimicrobial and antiradical properties and in situ control of Listeria monocytogenes in pork meat" in Meat Science, 96, no. 3 (2014):1355-1360,
https://doi.org/10.1016/j.meatsci.2013.11.024 . .
72
45
71

Novel and highly potent antitumour natural products from cnidarians of marine origin

Pejin, Boris; Mojović, Miloš; Savić, Aleksandar G

(Taylor & Francis Ltd, Abingdon, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Mojović, Miloš
AU  - Savić, Aleksandar G
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/805
AB  - This article covers the 2003-2012 literature published for marine natural products from the phylum Cnidaria. The focus is on new and highly potent antitumour substances, together with details related to the organism sourced. It describes 12 promising bioactives isolated from 7 species.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Novel and highly potent antitumour natural products from cnidarians of marine origin
EP  - 2244
IS  - 24
SP  - 2237
VL  - 28
DO  - 10.1080/14786419.2014.934241
ER  - 
@article{
author = "Pejin, Boris and Mojović, Miloš and Savić, Aleksandar G",
year = "2014",
abstract = "This article covers the 2003-2012 literature published for marine natural products from the phylum Cnidaria. The focus is on new and highly potent antitumour substances, together with details related to the organism sourced. It describes 12 promising bioactives isolated from 7 species.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Novel and highly potent antitumour natural products from cnidarians of marine origin",
pages = "2244-2237",
number = "24",
volume = "28",
doi = "10.1080/14786419.2014.934241"
}
Pejin, B., Mojović, M.,& Savić, A. G.. (2014). Novel and highly potent antitumour natural products from cnidarians of marine origin. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 28(24), 2237-2244.
https://doi.org/10.1080/14786419.2014.934241
Pejin B, Mojović M, Savić AG. Novel and highly potent antitumour natural products from cnidarians of marine origin. in Natural Product Research. 2014;28(24):2237-2244.
doi:10.1080/14786419.2014.934241 .
Pejin, Boris, Mojović, Miloš, Savić, Aleksandar G, "Novel and highly potent antitumour natural products from cnidarians of marine origin" in Natural Product Research, 28, no. 24 (2014):2237-2244,
https://doi.org/10.1080/14786419.2014.934241 . .
9
8
11

Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy

Pejin, Boris; Savić, Aleksandar G; Kien-Thai, Yong; Mojović, Miloš

(Adac-Cryptogamie, Paris, 2014)

TY  - JOUR
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Kien-Thai, Yong
AU  - Mojović, Miloš
PY  - 2014
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/756
AB  - The moss Rhodobryum ontariense tea has been claimed by Traditional Chinese medicine for its beneficial effects in the treatment of wide range of cardiovascular diseases including hypertension. The antiradical activity of R. ontariense tea (L e. its lyophilised water extract) was evaluated by electron paramagnetic resonance spectroscopy/against superoxide anion(center dot O-2(-)), nitric-oxide (center dot NO), 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH), carbon-dioxide anion (center dot CO2-) and methoxy (center dot CH2OH) radicals/ and fluorescence spectroscopy/against hydroxyl (center dot OH) radicals/ in in vitro conditions. It reduced the production of majority of radical species tested, but in a varying degree. The most activity was observed against center dot OH, center dot DPPH and center dot CO2- radicals (95 +/- 10%, 78 +/- 4% and 67 +/- 5%, respectively). In addition, the extract was shown to be active against center dot CH2OH and center dot NO radicals (55 +/- 8% and 45 +/- 8%, respectively). On the contrary, no any antiradical activity was observed against center dot O(2)(-)radicals. According to the experimental data obtained, R. ontariense tea can be considered as a promising resource of natural products with antiradical activity and may be of some interest to research in heart disease.
PB  - Adac-Cryptogamie, Paris
T2  - Cryptogamie Bryologie
T1  - Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy
EP  - 179
IS  - 2
SP  - 173
VL  - 35
DO  - 10.7872/cryb.v35.iss2.2014.173
ER  - 
@article{
author = "Pejin, Boris and Savić, Aleksandar G and Kien-Thai, Yong and Mojović, Miloš",
year = "2014",
abstract = "The moss Rhodobryum ontariense tea has been claimed by Traditional Chinese medicine for its beneficial effects in the treatment of wide range of cardiovascular diseases including hypertension. The antiradical activity of R. ontariense tea (L e. its lyophilised water extract) was evaluated by electron paramagnetic resonance spectroscopy/against superoxide anion(center dot O-2(-)), nitric-oxide (center dot NO), 2,2-diphenyl-1-picrylhydrazyl (center dot DPPH), carbon-dioxide anion (center dot CO2-) and methoxy (center dot CH2OH) radicals/ and fluorescence spectroscopy/against hydroxyl (center dot OH) radicals/ in in vitro conditions. It reduced the production of majority of radical species tested, but in a varying degree. The most activity was observed against center dot OH, center dot DPPH and center dot CO2- radicals (95 +/- 10%, 78 +/- 4% and 67 +/- 5%, respectively). In addition, the extract was shown to be active against center dot CH2OH and center dot NO radicals (55 +/- 8% and 45 +/- 8%, respectively). On the contrary, no any antiradical activity was observed against center dot O(2)(-)radicals. According to the experimental data obtained, R. ontariense tea can be considered as a promising resource of natural products with antiradical activity and may be of some interest to research in heart disease.",
publisher = "Adac-Cryptogamie, Paris",
journal = "Cryptogamie Bryologie",
title = "Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy",
pages = "179-173",
number = "2",
volume = "35",
doi = "10.7872/cryb.v35.iss2.2014.173"
}
Pejin, B., Savić, A. G., Kien-Thai, Y.,& Mojović, M.. (2014). Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy. in Cryptogamie Bryologie
Adac-Cryptogamie, Paris., 35(2), 173-179.
https://doi.org/10.7872/cryb.v35.iss2.2014.173
Pejin B, Savić AG, Kien-Thai Y, Mojović M. Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy. in Cryptogamie Bryologie. 2014;35(2):173-179.
doi:10.7872/cryb.v35.iss2.2014.173 .
Pejin, Boris, Savić, Aleksandar G, Kien-Thai, Yong, Mojović, Miloš, "Further in vitro evaluation of antiradical activity of the moss Rhodobryum ontariense tea using EPR and fluorescence spectroscopy" in Cryptogamie Bryologie, 35, no. 2 (2014):173-179,
https://doi.org/10.7872/cryb.v35.iss2.2014.173 . .
2
1

Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress

Savić, Aleksandar; Mitrović, Aleksandra Lj.; Simonović Radosavljević, Jasna; Bogdanović Pristov, Jelena; Steinbach, Gabor; Garab, G; Radotić, Ksenija

(Departmant of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, 2013)

TY  - CONF
AU  - Savić, Aleksandar
AU  - Mitrović, Aleksandra Lj.
AU  - Simonović Radosavljević, Jasna
AU  - Bogdanović Pristov, Jelena
AU  - Steinbach, Gabor
AU  - Garab, G
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2881
PB  - Departmant of Biology and Ecology, Faculty of Science and Mathematics, University of Niš
PB  - Biological Society "Dr Sava Petrović" Niš
C3  - 11th Symposium on the Flora of Southeastern Serbia and Neighbouring Regions
T1  - Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress
SP  - 120
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2881
ER  - 
@conference{
author = "Savić, Aleksandar and Mitrović, Aleksandra Lj. and Simonović Radosavljević, Jasna and Bogdanović Pristov, Jelena and Steinbach, Gabor and Garab, G and Radotić, Ksenija",
year = "2013",
publisher = "Departmant of Biology and Ecology, Faculty of Science and Mathematics, University of Niš, Biological Society "Dr Sava Petrović" Niš",
journal = "11th Symposium on the Flora of Southeastern Serbia and Neighbouring Regions",
title = "Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress",
pages = "120",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2881"
}
Savić, A., Mitrović, A. Lj., Simonović Radosavljević, J., Bogdanović Pristov, J., Steinbach, G., Garab, G.,& Radotić, K.. (2013). Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress. in 11th Symposium on the Flora of Southeastern Serbia and Neighbouring Regions
Departmant of Biology and Ecology, Faculty of Science and Mathematics, University of Niš., 120.
https://hdl.handle.net/21.15107/rcub_rimsi_2881
Savić A, Mitrović AL, Simonović Radosavljević J, Bogdanović Pristov J, Steinbach G, Garab G, Radotić K. Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress. in 11th Symposium on the Flora of Southeastern Serbia and Neighbouring Regions. 2013;:120.
https://hdl.handle.net/21.15107/rcub_rimsi_2881 .
Savić, Aleksandar, Mitrović, Aleksandra Lj., Simonović Radosavljević, Jasna, Bogdanović Pristov, Jelena, Steinbach, Gabor, Garab, G, Radotić, Ksenija, "Fluorescence detected linear dichroism of cellulose fibers in Picea omorika stems as a measure of mechanical stress" in 11th Symposium on the Flora of Southeastern Serbia and Neighbouring Regions (2013):120,
https://hdl.handle.net/21.15107/rcub_rimsi_2881 .

Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress

Govedarica, Marija; Tomović, Aleksandra; Kovačević, Jovana; Savić, Aleksandar; Simonović Radosavljević, Jasna; Maksimović, Vuk; Mutavdžić, Dragosav; Bogdanović Pristov, Jelena; Mitrović, Aleksandra Lj.; Radotić, Ksenija

(Serbian Plant Physiology Society, 2013)

TY  - CONF
AU  - Govedarica, Marija
AU  - Tomović, Aleksandra
AU  - Kovačević, Jovana
AU  - Savić, Aleksandar
AU  - Simonović Radosavljević, Jasna
AU  - Maksimović, Vuk
AU  - Mutavdžić, Dragosav
AU  - Bogdanović Pristov, Jelena
AU  - Mitrović, Aleksandra Lj.
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2883
PB  - Serbian Plant Physiology Society
PB  - Institute for Biological Research "Siniša Stankovic", University of Belgrade
C3  - 1st International Conference on Plant Biology, 20th Symposium of the Serbian Plant Physiology Society
T1  - Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress
EP  - 121
SP  - 120
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2883
ER  - 
@conference{
author = "Govedarica, Marija and Tomović, Aleksandra and Kovačević, Jovana and Savić, Aleksandar and Simonović Radosavljević, Jasna and Maksimović, Vuk and Mutavdžić, Dragosav and Bogdanović Pristov, Jelena and Mitrović, Aleksandra Lj. and Radotić, Ksenija",
year = "2013",
publisher = "Serbian Plant Physiology Society, Institute for Biological Research "Siniša Stankovic", University of Belgrade",
journal = "1st International Conference on Plant Biology, 20th Symposium of the Serbian Plant Physiology Society",
title = "Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress",
pages = "121-120",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2883"
}
Govedarica, M., Tomović, A., Kovačević, J., Savić, A., Simonović Radosavljević, J., Maksimović, V., Mutavdžić, D., Bogdanović Pristov, J., Mitrović, A. Lj.,& Radotić, K.. (2013). Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress. in 1st International Conference on Plant Biology, 20th Symposium of the Serbian Plant Physiology Society
Serbian Plant Physiology Society., 120-121.
https://hdl.handle.net/21.15107/rcub_rimsi_2883
Govedarica M, Tomović A, Kovačević J, Savić A, Simonović Radosavljević J, Maksimović V, Mutavdžić D, Bogdanović Pristov J, Mitrović AL, Radotić K. Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress. in 1st International Conference on Plant Biology, 20th Symposium of the Serbian Plant Physiology Society. 2013;:120-121.
https://hdl.handle.net/21.15107/rcub_rimsi_2883 .
Govedarica, Marija, Tomović, Aleksandra, Kovačević, Jovana, Savić, Aleksandar, Simonović Radosavljević, Jasna, Maksimović, Vuk, Mutavdžić, Dragosav, Bogdanović Pristov, Jelena, Mitrović, Aleksandra Lj., Radotić, Ksenija, "Compression wood formation as a response of Picea omorika (Pančić) Purkynĕ to static bending stress" in 1st International Conference on Plant Biology, 20th Symposium of the Serbian Plant Physiology Society (2013):120-121,
https://hdl.handle.net/21.15107/rcub_rimsi_2883 .

Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica

Ducic, Tanja; Borchert, Manuela; Savić, Aleksandar G; Kalauzi, Aleksandar; Mitrović, Aleksandra Lj.; Radotić, Ksenija

(Wiley-Blackwell, Hoboken, 2013)

TY  - JOUR
AU  - Ducic, Tanja
AU  - Borchert, Manuela
AU  - Savić, Aleksandar G
AU  - Kalauzi, Aleksandar
AU  - Mitrović, Aleksandra Lj.
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/696
AB  - Synchrotron-based X-ray microfluorescence (mu SXRF) is an analytical method suitable for in situ investigation of the distribution of micronutrient and macronutrient elements in several-micrometres-thick unstained biological samples, e. g. single cells and tissues. Elements are mapped and quantified at sub-p. p. m. concentrations. In this study the quantity, distribution and grouping/co-localization of various elements have been identified in straight and twisted internodes of the stems of the monocotyledonous climber D. balcanica Kosanin. Three different statistical methods were employed to analyse the macronutrient and micronutrient distributions and co-localization. Macronutrient elements (K, P, Ca, Cl) are distributed homogeneously in both straight and twisted internodes. Micronutrient elements are mostly grouped in the vasculature and in the sclerenchyma cell layer. In addition, co-localization of micronutrient elements is much more prominent in twisted than in straight internodes. These image analyses and statistical methods provided very similar outcomes and could be applied to various types of biological samples imaged by mSXRF.
PB  - Wiley-Blackwell, Hoboken
T2  - Journal of Synchrotron Radiation
T1  - Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica
EP  - 346
SP  - 339
VL  - 20
DO  - 10.1107/S0909049512050170
ER  - 
@article{
author = "Ducic, Tanja and Borchert, Manuela and Savić, Aleksandar G and Kalauzi, Aleksandar and Mitrović, Aleksandra Lj. and Radotić, Ksenija",
year = "2013",
abstract = "Synchrotron-based X-ray microfluorescence (mu SXRF) is an analytical method suitable for in situ investigation of the distribution of micronutrient and macronutrient elements in several-micrometres-thick unstained biological samples, e. g. single cells and tissues. Elements are mapped and quantified at sub-p. p. m. concentrations. In this study the quantity, distribution and grouping/co-localization of various elements have been identified in straight and twisted internodes of the stems of the monocotyledonous climber D. balcanica Kosanin. Three different statistical methods were employed to analyse the macronutrient and micronutrient distributions and co-localization. Macronutrient elements (K, P, Ca, Cl) are distributed homogeneously in both straight and twisted internodes. Micronutrient elements are mostly grouped in the vasculature and in the sclerenchyma cell layer. In addition, co-localization of micronutrient elements is much more prominent in twisted than in straight internodes. These image analyses and statistical methods provided very similar outcomes and could be applied to various types of biological samples imaged by mSXRF.",
publisher = "Wiley-Blackwell, Hoboken",
journal = "Journal of Synchrotron Radiation",
title = "Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica",
pages = "346-339",
volume = "20",
doi = "10.1107/S0909049512050170"
}
Ducic, T., Borchert, M., Savić, A. G., Kalauzi, A., Mitrović, A. Lj.,& Radotić, K.. (2013). Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica. in Journal of Synchrotron Radiation
Wiley-Blackwell, Hoboken., 20, 339-346.
https://doi.org/10.1107/S0909049512050170
Ducic T, Borchert M, Savić AG, Kalauzi A, Mitrović AL, Radotić K. Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica. in Journal of Synchrotron Radiation. 2013;20:339-346.
doi:10.1107/S0909049512050170 .
Ducic, Tanja, Borchert, Manuela, Savić, Aleksandar G, Kalauzi, Aleksandar, Mitrović, Aleksandra Lj., Radotić, Ksenija, "Enhancement in statistical and image analysis for in situ mu SXRF studies of elemental distribution and co-localization, using Dioscorea balcanica" in Journal of Synchrotron Radiation, 20 (2013):339-346,
https://doi.org/10.1107/S0909049512050170 . .
3
3
3

Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins

Savić, Aleksandar G; Kardos, Roland; Nyitrai, Miklos; Radotić, Ksenija

(Springer/Plenum Publishers, New York, 2013)

TY  - JOUR
AU  - Savić, Aleksandar G
AU  - Kardos, Roland
AU  - Nyitrai, Miklos
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/735
AB  - Despite of widely application of multivariate analysis in chemometrics, problem of resolving closely positioned components in the fluorescence spectra remained unsolved, thus limiting the usage of fluorescence spectroscopy in analytical purpose. In this paper we have described a novel procedure, adapted especially for the analysis of complex fluorescence spectra with multiple, closely positioned components' maxima. The method was first tested on the simulated spectra and then applied on the spectra of proteins whose fluorophores have similar properties of both the excitation and the emission spectra. In this paper, simple but efficient modification of the method was applied. Instead of analyzing full size emission matrix (12 spectra), 9 spectra wide windows were analyzed, and 4 factors (greatest possible number of factors with physical meaning both for actin and simulated spectra) were extracted in each pass. Obtained factor scores were grouped by using the K-means algorithm. Groups of factor scores obtained from K-means algorithm were passed through the one more factor analysis (FA) in order to find one factor that represents each group. Our approach provides resolution of extremely closed spectral components, which is a vital data for protein conformation analysis based on fluorescence spectroscopy.
PB  - Springer/Plenum Publishers, New York
T2  - Journal of Fluorescence
T1  - Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins
EP  - 610
IS  - 3
SP  - 605
VL  - 23
DO  - 10.1007/s10895-013-1183-0
ER  - 
@article{
author = "Savić, Aleksandar G and Kardos, Roland and Nyitrai, Miklos and Radotić, Ksenija",
year = "2013",
abstract = "Despite of widely application of multivariate analysis in chemometrics, problem of resolving closely positioned components in the fluorescence spectra remained unsolved, thus limiting the usage of fluorescence spectroscopy in analytical purpose. In this paper we have described a novel procedure, adapted especially for the analysis of complex fluorescence spectra with multiple, closely positioned components' maxima. The method was first tested on the simulated spectra and then applied on the spectra of proteins whose fluorophores have similar properties of both the excitation and the emission spectra. In this paper, simple but efficient modification of the method was applied. Instead of analyzing full size emission matrix (12 spectra), 9 spectra wide windows were analyzed, and 4 factors (greatest possible number of factors with physical meaning both for actin and simulated spectra) were extracted in each pass. Obtained factor scores were grouped by using the K-means algorithm. Groups of factor scores obtained from K-means algorithm were passed through the one more factor analysis (FA) in order to find one factor that represents each group. Our approach provides resolution of extremely closed spectral components, which is a vital data for protein conformation analysis based on fluorescence spectroscopy.",
publisher = "Springer/Plenum Publishers, New York",
journal = "Journal of Fluorescence",
title = "Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins",
pages = "610-605",
number = "3",
volume = "23",
doi = "10.1007/s10895-013-1183-0"
}
Savić, A. G., Kardos, R., Nyitrai, M.,& Radotić, K.. (2013). Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins. in Journal of Fluorescence
Springer/Plenum Publishers, New York., 23(3), 605-610.
https://doi.org/10.1007/s10895-013-1183-0
Savić AG, Kardos R, Nyitrai M, Radotić K. Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins. in Journal of Fluorescence. 2013;23(3):605-610.
doi:10.1007/s10895-013-1183-0 .
Savić, Aleksandar G, Kardos, Roland, Nyitrai, Miklos, Radotić, Ksenija, "Decomposition of Complex Fluorescence Spectra Containing Components with Close Emission Maxima Positions and Similar Quantum Yields. Application to Fluorescence Spectra of Proteins" in Journal of Fluorescence, 23, no. 3 (2013):605-610,
https://doi.org/10.1007/s10895-013-1183-0 . .
2
2

Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR

Jovanović, Katarina K; Savić, Aleksandar G; Janković, Radmila N; Radulović, Sinisa S; Spasić, Slađana; Radotić, Ksenija

(Churchill Livingstone, Edinburgh, 2013)

TY  - JOUR
AU  - Jovanović, Katarina K
AU  - Savić, Aleksandar G
AU  - Janković, Radmila N
AU  - Radulović, Sinisa S
AU  - Spasić, Slađana
AU  - Radotić, Ksenija
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/702
AB  - The key method for therapies of various cancer types could be the molecular-targeted therapy, based on individual gene profile for each patient. One of the main procedures used for genetic testing is the real-time polymerase chain reaction (real-time PCR). Physical principle behind real-time PCR procedure is the fluorescence. Fluorescence labeled probes (primers) is attached to quenchers. Upon reaction of polymerization, quenchers are removed, and the fluorescence emission intensity increases in time. Emission spectra shape and its maximum position can differ if the fluorophore was present in different microenvironment. That property is widely exploited in fluorescence spectroscopy and chromatography. This paper, for the first time, describes utilization of full spectroscopic potential of multichannel excitation/emission filter sets in real-time PCR device. Instead of monitoring fluorescence intensity in time for a single fluorescence emission channel, the ratio values of three different kinetics curves were calculated and analyzed by applying k-means clustering and dendrogram analysis. Obtained results have shown that described analytical improvement provides identification of nine different groups of mutations if the commercial QIAGEN (R) EGFR PCR Kit was used. Method can be applied to any kit, capable to simultaneously detect several different mutations.
PB  - Churchill Livingstone, Edinburgh
T2  - Medical Hypotheses
T1  - Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR
EP  - 379
IS  - 4
SP  - 376
VL  - 80
DO  - 10.1016/j.mehy.2013.01.004
ER  - 
@article{
author = "Jovanović, Katarina K and Savić, Aleksandar G and Janković, Radmila N and Radulović, Sinisa S and Spasić, Slađana and Radotić, Ksenija",
year = "2013",
abstract = "The key method for therapies of various cancer types could be the molecular-targeted therapy, based on individual gene profile for each patient. One of the main procedures used for genetic testing is the real-time polymerase chain reaction (real-time PCR). Physical principle behind real-time PCR procedure is the fluorescence. Fluorescence labeled probes (primers) is attached to quenchers. Upon reaction of polymerization, quenchers are removed, and the fluorescence emission intensity increases in time. Emission spectra shape and its maximum position can differ if the fluorophore was present in different microenvironment. That property is widely exploited in fluorescence spectroscopy and chromatography. This paper, for the first time, describes utilization of full spectroscopic potential of multichannel excitation/emission filter sets in real-time PCR device. Instead of monitoring fluorescence intensity in time for a single fluorescence emission channel, the ratio values of three different kinetics curves were calculated and analyzed by applying k-means clustering and dendrogram analysis. Obtained results have shown that described analytical improvement provides identification of nine different groups of mutations if the commercial QIAGEN (R) EGFR PCR Kit was used. Method can be applied to any kit, capable to simultaneously detect several different mutations.",
publisher = "Churchill Livingstone, Edinburgh",
journal = "Medical Hypotheses",
title = "Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR",
pages = "379-376",
number = "4",
volume = "80",
doi = "10.1016/j.mehy.2013.01.004"
}
Jovanović, K. K., Savić, A. G., Janković, R. N., Radulović, S. S., Spasić, S.,& Radotić, K.. (2013). Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR. in Medical Hypotheses
Churchill Livingstone, Edinburgh., 80(4), 376-379.
https://doi.org/10.1016/j.mehy.2013.01.004
Jovanović KK, Savić AG, Janković RN, Radulović SS, Spasić S, Radotić K. Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR. in Medical Hypotheses. 2013;80(4):376-379.
doi:10.1016/j.mehy.2013.01.004 .
Jovanović, Katarina K, Savić, Aleksandar G, Janković, Radmila N, Radulović, Sinisa S, Spasić, Slađana, Radotić, Ksenija, "Detection of DNA mutations based on analysis of multiple wavelength excitation/emission fluorescence kinetics curves in real-time PCR" in Medical Hypotheses, 80, no. 4 (2013):376-379,
https://doi.org/10.1016/j.mehy.2013.01.004 . .
1
1
1

Chemical composition and biological activity of Gaultheria procumbens L. essential oil

Nikolic, Milos MN; Marković, Tatjana; Mojović, Miloš; Pejin, Boris; Savić, Aleksandar G; Peric, Tamara O; Marković, Dejan Lj; Stević, Tatjana R; Soković, Marina

(Elsevier, Amsterdam, 2013)

TY  - JOUR
AU  - Nikolic, Milos MN
AU  - Marković, Tatjana
AU  - Mojović, Miloš
AU  - Pejin, Boris
AU  - Savić, Aleksandar G
AU  - Peric, Tamara O
AU  - Marković, Dejan Lj
AU  - Stević, Tatjana R
AU  - Soković, Marina
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/675
AB  - The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.
PB  - Elsevier, Amsterdam
T2  - Industrial Crops and Products
T1  - Chemical composition and biological activity of Gaultheria procumbens L. essential oil
EP  - 567
SP  - 561
VL  - 49
DO  - 10.1016/j.indcrop.2013.06.002
ER  - 
@article{
author = "Nikolic, Milos MN and Marković, Tatjana and Mojović, Miloš and Pejin, Boris and Savić, Aleksandar G and Peric, Tamara O and Marković, Dejan Lj and Stević, Tatjana R and Soković, Marina",
year = "2013",
abstract = "The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e. food and oral bacteria and fungi, respectively (MIC 0.18-3.00 mg/ml and MBC 1.25-4.00 mg/ml; MIC 0.73-5.00 mg/ml and MFC 2.92-26.67 mg/ml); The oil effectively inhibited the biofilm formation of oral Streptococcus mutans and Candida albicans as well (MIC 25.00 MBC 50.00 mg/ml; MIC 12.50, MFC 50.00 mg/ml). In addition, oil exhibited a dose-dependent DPPH-radical-scavenging activity with IC50 value of 30.61 mg/ml. The specific fluorescence probe 2-[6-(4'-amino)phenoxy-3H-xanten-3-on-9-yl] benzoic acid (APP) and the the spin trap 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO), capable for simultaneous detection of different free radical specie were used in antiradical activity of the oil measurements. Oil showed a moderate antiradical activity, reducing quantity of produced hydroxyl radicals to about 20% of initial value. This study succeeds in creating directly comparable and quantitative data for the oil unsufficiently examined so far.",
publisher = "Elsevier, Amsterdam",
journal = "Industrial Crops and Products",
title = "Chemical composition and biological activity of Gaultheria procumbens L. essential oil",
pages = "567-561",
volume = "49",
doi = "10.1016/j.indcrop.2013.06.002"
}
Nikolic, M. M., Marković, T., Mojović, M., Pejin, B., Savić, A. G., Peric, T. O., Marković, D. L., Stević, T. R.,& Soković, M.. (2013). Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products
Elsevier, Amsterdam., 49, 561-567.
https://doi.org/10.1016/j.indcrop.2013.06.002
Nikolic MM, Marković T, Mojović M, Pejin B, Savić AG, Peric TO, Marković DL, Stević TR, Soković M. Chemical composition and biological activity of Gaultheria procumbens L. essential oil. in Industrial Crops and Products. 2013;49:561-567.
doi:10.1016/j.indcrop.2013.06.002 .
Nikolic, Milos MN, Marković, Tatjana, Mojović, Miloš, Pejin, Boris, Savić, Aleksandar G, Peric, Tamara O, Marković, Dejan Lj, Stević, Tatjana R, Soković, Marina, "Chemical composition and biological activity of Gaultheria procumbens L. essential oil" in Industrial Crops and Products, 49 (2013):561-567,
https://doi.org/10.1016/j.indcrop.2013.06.002 . .
3
68
51
76

New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012

Pejin, Boris; Jovanović, Katarina K; Mojović, Miloš; Savić, Aleksandar G

(Bentham Science Publ Ltd, Sharjah, 2013)

TY  - JOUR
AU  - Pejin, Boris
AU  - Jovanović, Katarina K
AU  - Mojović, Miloš
AU  - Savić, Aleksandar G
PY  - 2013
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/654
AB  - This review covers the 2003-2012 literature data published for antitumor natural products from marine-derived fungi. The focus is on new and highly potent cytotoxic compounds, together with details related to the relevant fungal species. It describes 22 promising bioactives, originating mainly from symbiotic fungi. The chemical structures of all highlighted organic molecules are briefly discussed.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Topics in Medicinal Chemistry
T1  - New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012
EP  - 2766
IS  - 21
SP  - 2745
VL  - 13
DO  - 10.2174/15680266113136660197
ER  - 
@article{
author = "Pejin, Boris and Jovanović, Katarina K and Mojović, Miloš and Savić, Aleksandar G",
year = "2013",
abstract = "This review covers the 2003-2012 literature data published for antitumor natural products from marine-derived fungi. The focus is on new and highly potent cytotoxic compounds, together with details related to the relevant fungal species. It describes 22 promising bioactives, originating mainly from symbiotic fungi. The chemical structures of all highlighted organic molecules are briefly discussed.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Topics in Medicinal Chemistry",
title = "New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012",
pages = "2766-2745",
number = "21",
volume = "13",
doi = "10.2174/15680266113136660197"
}
Pejin, B., Jovanović, K. K., Mojović, M.,& Savić, A. G.. (2013). New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012. in Current Topics in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 13(21), 2745-2766.
https://doi.org/10.2174/15680266113136660197
Pejin B, Jovanović KK, Mojović M, Savić AG. New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012. in Current Topics in Medicinal Chemistry. 2013;13(21):2745-2766.
doi:10.2174/15680266113136660197 .
Pejin, Boris, Jovanović, Katarina K, Mojović, Miloš, Savić, Aleksandar G, "New and Highly Potent Antitumor Natural Products from Marine-Derived Fungi: Covering the Period from 2003 to 2012" in Current Topics in Medicinal Chemistry, 13, no. 21 (2013):2745-2766,
https://doi.org/10.2174/15680266113136660197 . .
67
37
74

Advanced analysis of multi channel real-time PCR kinetics

Janković, Radmila; Katarina, Jovanović; Radulović, Siniša; Savić, Aleksandar; Spasić, Slađana; Radotić, Ksenija

(Biophysical Society of Serbia, Srbija, 2012)

TY  - CONF
AU  - Janković, Radmila
AU  - Katarina, Jovanović
AU  - Radulović, Siniša
AU  - Savić, Aleksandar
AU  - Spasić, Slađana
AU  - Radotić, Ksenija
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2823
PB  - Biophysical Society of Serbia, Srbija
C3  - Regional Biophysics Conference
T1  - Advanced analysis of multi channel real-time PCR kinetics
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2823
ER  - 
@conference{
author = "Janković, Radmila and Katarina, Jovanović and Radulović, Siniša and Savić, Aleksandar and Spasić, Slađana and Radotić, Ksenija",
year = "2012",
publisher = "Biophysical Society of Serbia, Srbija",
journal = "Regional Biophysics Conference",
title = "Advanced analysis of multi channel real-time PCR kinetics",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2823"
}
Janković, R., Katarina, J., Radulović, S., Savić, A., Spasić, S.,& Radotić, K.. (2012). Advanced analysis of multi channel real-time PCR kinetics. in Regional Biophysics Conference
Biophysical Society of Serbia, Srbija..
https://hdl.handle.net/21.15107/rcub_rimsi_2823
Janković R, Katarina J, Radulović S, Savić A, Spasić S, Radotić K. Advanced analysis of multi channel real-time PCR kinetics. in Regional Biophysics Conference. 2012;.
https://hdl.handle.net/21.15107/rcub_rimsi_2823 .
Janković, Radmila, Katarina, Jovanović, Radulović, Siniša, Savić, Aleksandar, Spasić, Slađana, Radotić, Ksenija, "Advanced analysis of multi channel real-time PCR kinetics" in Regional Biophysics Conference (2012),
https://hdl.handle.net/21.15107/rcub_rimsi_2823 .

Determination of gene point mutations by application of higher order central moments - Preliminary research

Savić, Aleksandar G; Jovanović, Katarina K; Janković, R.; Radotić, Ksenija; Spasić, Slađana

(2012)

TY  - CONF
AU  - Savić, Aleksandar G
AU  - Jovanović, Katarina K
AU  - Janković, R.
AU  - Radotić, Ksenija
AU  - Spasić, Slađana
PY  - 2012
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/563
AB  - Point mutations in conserved gene sequences are used as the trace marker for determination of evolutionary distance among the species. Novel method is based on calculation of nucleotide occurrence probability in fixed size moving window and determination of high order central moments. Description of nucleotide occurrence probability can provide high accuracy point mutation detection, and the insight into local sequence.
C3  - 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings
T1  - Determination of gene point mutations by application of higher order central moments - Preliminary research
EP  - 866
SP  - 863
DO  - 10.1109/TELFOR.2012.6419344
ER  - 
@conference{
author = "Savić, Aleksandar G and Jovanović, Katarina K and Janković, R. and Radotić, Ksenija and Spasić, Slađana",
year = "2012",
abstract = "Point mutations in conserved gene sequences are used as the trace marker for determination of evolutionary distance among the species. Novel method is based on calculation of nucleotide occurrence probability in fixed size moving window and determination of high order central moments. Description of nucleotide occurrence probability can provide high accuracy point mutation detection, and the insight into local sequence.",
journal = "2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings",
title = "Determination of gene point mutations by application of higher order central moments - Preliminary research",
pages = "866-863",
doi = "10.1109/TELFOR.2012.6419344"
}
Savić, A. G., Jovanović, K. K., Janković, R., Radotić, K.,& Spasić, S.. (2012). Determination of gene point mutations by application of higher order central moments - Preliminary research. in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings, 863-866.
https://doi.org/10.1109/TELFOR.2012.6419344
Savić AG, Jovanović KK, Janković R, Radotić K, Spasić S. Determination of gene point mutations by application of higher order central moments - Preliminary research. in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings. 2012;:863-866.
doi:10.1109/TELFOR.2012.6419344 .
Savić, Aleksandar G, Jovanović, Katarina K, Janković, R., Radotić, Ksenija, Spasić, Slađana, "Determination of gene point mutations by application of higher order central moments - Preliminary research" in 2012 20th Telecommunications Forum, TELFOR 2012 - Proceedings (2012):863-866,
https://doi.org/10.1109/TELFOR.2012.6419344 . .