TY  - CONF
AU  - Vukašinović, Jelena
AU  - Babic, Nikolina
AU  - Todorović, Tamara
AU  - Filipović, Nenad
PY  - 2016
UR  - http://rimsi.imsi.bg.ac.rs/handle/123456789/2079
AB  - The aim of this study was to elucidate the structure, geometry and biological activity of platinum(II) and palladium(II) complexes with different quinoline derivatives of thiosemicar-bazones. Four novel platinum(II) and palladium(II) complexes with 2-quinolinecarboxaldehyde thiosemikarbazone (H2QATSC) and 8-quinolinecarboxaldehyde thiosemikarbazone (H8QATSC) were synthesized. The complexes of platinum(II) and palladium(II) with H2QATSC ligand, [PtCl(2QATSC)] (1) and [PdCl(2QATSC)] (2), were synthesized by direct reaction and charac-terized by single crystal X-ray analysis. The complexes of platinum(II) and palladium(II) with H8QATSC ligand, [PtCl(8QATSC)] (3) and [PdCl(8QATSC)] (4), were characterized by NMR spectroscopy. In the complexes 1–4 ligands are coordinated tridentately via the quinoline and imine nitrogen atoms and thiosemicarbazone sulfur atom, forming two five-membered rings with metal ion. The geometry around metal ions is square-planar, where chloride ion occupies fourth coordination site. Antitumor activity of the complexes 1–4 was investigated and com-pared with the activity of cisplatin.
PB  - Serbian Chemical Society
C3  - 4th Conference of Young Chemists of Serbia, 5 November, 2016, Belgrade, Serbia
T1  - Synthesis, characterization and biological activity of platinum(II) and palladium(II) complexes with quinoline derivatives of thiosemicarbazones
SP  - 37
UR  - https://hdl.handle.net/21.15107/rcub_rimsi_2079
ER  - 

@conference{
author = "Vukašinović, Jelena and Babic, Nikolina and Todorović, Tamara and Filipović, Nenad",
year = "2016",
abstract = "The aim of this study was to elucidate the structure, geometry and biological activity of platinum(II) and palladium(II) complexes with different quinoline derivatives of thiosemicar-bazones. Four novel platinum(II) and palladium(II) complexes with 2-quinolinecarboxaldehyde thiosemikarbazone (H2QATSC) and 8-quinolinecarboxaldehyde thiosemikarbazone (H8QATSC) were synthesized. The complexes of platinum(II) and palladium(II) with H2QATSC ligand, [PtCl(2QATSC)] (1) and [PdCl(2QATSC)] (2), were synthesized by direct reaction and charac-terized by single crystal X-ray analysis. The complexes of platinum(II) and palladium(II) with H8QATSC ligand, [PtCl(8QATSC)] (3) and [PdCl(8QATSC)] (4), were characterized by NMR spectroscopy. In the complexes 1–4 ligands are coordinated tridentately via the quinoline and imine nitrogen atoms and thiosemicarbazone sulfur atom, forming two five-membered rings with metal ion. The geometry around metal ions is square-planar, where chloride ion occupies fourth coordination site. Antitumor activity of the complexes 1–4 was investigated and com-pared with the activity of cisplatin.",
publisher = "Serbian Chemical Society",
journal = "4th Conference of Young Chemists of Serbia, 5 November, 2016, Belgrade, Serbia",
title = "Synthesis, characterization and biological activity of platinum(II) and palladium(II) complexes with quinoline derivatives of thiosemicarbazones",
pages = "37",
url = "https://hdl.handle.net/21.15107/rcub_rimsi_2079"
}

Vukašinović, J., Babic, N., Todorović, T.,& Filipović, N.. (2016). Synthesis, characterization and biological activity of platinum(II) and palladium(II) complexes with quinoline derivatives of thiosemicarbazones. in 4th Conference of Young Chemists of Serbia, 5 November, 2016, Belgrade, Serbia
Serbian Chemical Society., 37.
https://hdl.handle.net/21.15107/rcub_rimsi_2079

Vukašinović J, Babic N, Todorović T, Filipović N. Synthesis, characterization and biological activity of platinum(II) and palladium(II) complexes with quinoline derivatives of thiosemicarbazones. in 4th Conference of Young Chemists of Serbia, 5 November, 2016, Belgrade, Serbia. 2016;:37.
https://hdl.handle.net/21.15107/rcub_rimsi_2079 .

Vukašinović, Jelena, Babic, Nikolina, Todorović, Tamara, Filipović, Nenad, "Synthesis, characterization and biological activity of platinum(II) and palladium(II) complexes with quinoline derivatives of thiosemicarbazones" in 4th Conference of Young Chemists of Serbia, 5 November, 2016, Belgrade, Serbia (2016):37,
https://hdl.handle.net/21.15107/rcub_rimsi_2079 .